Achieving optimal alignment in total knee arthroplasty(TKA)is a critical factor in ensuring optimal outcomes and long-term implant survival.Traditionally,mechanical alignment has been favored to achieve neutral post-o...Achieving optimal alignment in total knee arthroplasty(TKA)is a critical factor in ensuring optimal outcomes and long-term implant survival.Traditionally,mechanical alignment has been favored to achieve neutral post-operative joint alignment.However,contemporary approaches,such as kinematic alignments and hybrid techniques including adjusted mechanical,restricted kinematic,inverse kinematic,and functional alignments,are gaining attention for their ability to restore native joint kinematics and anatomical alignment,potentially leading to enhanced functional outcomes and greater patient satisfaction.The ongoing debate on optimal alignment strategies considers the following factors:long-term implant durability,functional improvement,and resolution of individual anatomical variations.Furthermore,advancements of computer-navigated and robotic-assisted surgery has augmented the precision in implant positioning and objective measurements of soft tissue balance.Despite ongoing debates on balancing implant longevity and functional outcomes,there is an increasing advocacy for personalized alignment strategies that are tailored to individual anatomical variations.This review evaluates the spectrum of various alignment techniques in TKA,including mechanical alignment,patient-specific kinematic approaches,and emerging hybrid methods.Each technique is scrutinized based on its fundamental principles,procedural techniques,inherent advantages,and potential limitations,while identifying significant clinical gaps that underscore the need for further investigation.展开更多
This paper presents an improved voice morphing algorithm based on Gaussian Mixture Model(GMM) which overcomes the traditional one in the terms of overly smoothed problems of the converted spectral and discontinuities ...This paper presents an improved voice morphing algorithm based on Gaussian Mixture Model(GMM) which overcomes the traditional one in the terms of overly smoothed problems of the converted spectral and discontinuities between frames.Firstly, a maximum likelihood estimation for the model is introduced for the alleviation of the inversion of high dimension matrixes caused by traditional conversion function.Then, in order to resolve the two problems associated with the baseline, a codebook compensation technique and a time domain medial filter are applied.The results of listening evaluations show that the quality of the speech converted by the proposed method is significantly better than that by the traditional GMM method, and the Mean Opinion Score(MOS) of the converted speech is improved from 2.5 to 3.1 and ABX score from 38% to 75%.展开更多
A new multifunctional testing device for rock fragmentation was introduced, which can conduct many experiments such as single cutting under static load, crushing under impact load, thrusting under static load and cutt...A new multifunctional testing device for rock fragmentation was introduced, which can conduct many experiments such as single cutting under static load, crushing under impact load, thrusting under static load and cutting-impact test under the dynamic and static load. The results of granite and concrete抯 experiments with polycrystalline diamond compact (PDC) flat cutters and carbide alloy cutters under different loadings show that the device has good performance, and the characteristics of broken rock under the combined loads are similar to that under the single static pressure or impact crushing the rock, and the combined loads can increase the effect of rock fragmentation obviously. The experimental methods and effects have the important meaning for studying new drill-ing tool on hard rock fragmentation.展开更多
A new method of prefetching data blocks from the NVCache to the page cache in main memory and cascading prefetching n-blocks from a hard disk to the NVCache together was proposed to reduce the spin-up frequency of a h...A new method of prefetching data blocks from the NVCache to the page cache in main memory and cascading prefetching n-blocks from a hard disk to the NVCache together was proposed to reduce the spin-up frequency of a hybrid hard disk drive and thus enhance I/O performance.The proposed method consists of three steps:1) Analyzing the pattern of read requests in block units;2) Determining the number of blocks prefetched to the NVCache;3) Replacing blocks in the NVCache according to the block replacement policy.The proposed method can reduce the latency time of a hybrid hard disk and optimize the power consumption of an IPTV set-top box.Experimental results show that the proposed method provides better average response time compared to an existing adaptive multistream prefetching(AMP) method by 25.17%.It also reduces by 20.83% the average power consumption over that of the existing external caching in energy saving storage system(EXCES) method.展开更多
The changes of several immune functions were observed in rats after they were inflicted with 6 Gy gamma rays irradiation, 15% TBSA full thickness brun and the combination of the 2 injuries. It was found that the funct...The changes of several immune functions were observed in rats after they were inflicted with 6 Gy gamma rays irradiation, 15% TBSA full thickness brun and the combination of the 2 injuries. It was found that the functions of thymocytes and splenocytes suffered the most severe suppression in the 24th to 72nd hour after radiation injury and began to recover on the 7th day. In the rats with burn injury, the suppression on thymocytes and splenocytes were significantly less severe than that after radiation and recovered more rapidly. The effects of combined radiation-burn injury showed several characteristics. The suppression on the thymocytes was more severe with slower recovery as compared with that after single radiation injury only. The suppression on the splenocytes as a whole was similar to that after single radiation injury , but in the early stage after combined injury, the suppression was far more severe than that after radiation Escharectomy and skin grafting on the burn wounds on the lst day after combined injury could accelerate the recovery on both the thymocytes and splenocytes. Our findings indicated that the severity of the suppression on the immune functions due to combined radiation-burn injury might depend on the size of the burn wounds.展开更多
To improve motion graph based motion synthesis,semantic control was introduced.Hybrid motion features including both numerical and user-defined semantic relational features were extracted to encode the characteristic ...To improve motion graph based motion synthesis,semantic control was introduced.Hybrid motion features including both numerical and user-defined semantic relational features were extracted to encode the characteristic aspects contained in the character's poses of the given motion sequences.Motion templates were then automatically derived from the training motions for capturing the spatio-temporal characteristics of an entire given class of semantically related motions.The data streams of motion documents were automatically annotated with semantic motion class labels by matching their respective motion class templates.Finally,the semantic control was introduced into motion graph based human motion synthesis.Experiments of motion synthesis demonstrate the effectiveness of the approach which enables users higher level of semantically intuitive control and high quality in human motion synthesis from motion capture database.展开更多
An approach was presented to intensify the mixing process. Firstly, a novel concept, the dissipation of mass transfer ability(DMA) associated with convective mass transfer, was defined via an analogy to the heat-work ...An approach was presented to intensify the mixing process. Firstly, a novel concept, the dissipation of mass transfer ability(DMA) associated with convective mass transfer, was defined via an analogy to the heat-work conversion. Accordingly, the focus on mass transfer enhancement can be shifted to seek the extremum of the DMA of the system. To this end, an optimization principle was proposed. A mathematical model was then developed to formulate the optimization into a variational problem. Subsequently, the intensification of the mixing process for a gas mixture in a micro-tube was provided to demonstrate the proposed principle. In the demonstration example, an optimized velocity field was obtained in which the mixing ability was improved, i.e., the mixing process should be intensified by adjusting the velocity field in related equipment. Therefore, a specific procedure was provided to produce a mixer with geometric irregularities associated with an ideal velocity.展开更多
Chromate and dichromate sodium as a function of oxidizer characteristics are used in several industrial areas; for example, in surface protection of coated parts of cadmium, zinc and aluminum (chromate coated treated...Chromate and dichromate sodium as a function of oxidizer characteristics are used in several industrial areas; for example, in surface protection of coated parts of cadmium, zinc and aluminum (chromate coated treated), corrosion inhibitors, the treatment of leather, the manufacture of pigments, etc. However, the use of such products has been questioned due to the problems of toxicity and pollution that can be caused in the environmental. The Brazilian environmental agency has established that the concentrations of chromate in water courses are less than 0.5 ppm. In order to reuse chromate (CrO42) from industrial effluent, laboratory experiments have been proposed based on chemical reduction or electrolytic processes, in order to transform these chromate ions in a final mix of oxides (in solid form), which can then be packed and sent to the production process of sodium chromate. The results of these experiments have become useful industrially (without regard to costs) considering the environmental reuse and the life cycle of the chemical compound.展开更多
OBJECTIVE: To explore the short and long-term efficacy of combining Fuzhengliqi mixture (FLM) with acupuncture in treating functional constipation (FC). METHODS: The 560 patients with confirmed diagnosis of FC were ra...OBJECTIVE: To explore the short and long-term efficacy of combining Fuzhengliqi mixture (FLM) with acupuncture in treating functional constipation (FC). METHODS: The 560 patients with confirmed diagnosis of FC were randomly assigned to four groups: FLM group, acupuncture group, combined therapy group, and control group. There were 140 cases in each group. The FLM group was administered FLM 60 mL twice a day, while the acupuncture group was treated with acupuncture at acupoints Tianshu (ST 25), Shangjuxu (ST 37), Zusanli (ST 36), Dachangshu (BL 25), and Zhigou (TE 6) twice a day, the combined therapy group with FLM and acupuncture, and the control group was administered mosapride (5 mg thrice a day) and Macrogol 4000 (10 g twice a day). The treatment lasted 6 weeks. The defecation interval, stool property, constipation symptoms, and accompanying symptomswere recorded, graded, and scored.The gastrointestinal transit time (GITT) and motilin (MTL) level in serum and life quality score were detected at three time points (pre-treatment, at the end of treatment, and 60 weeks post-treatment). Moreover, the adverse reactions were also observed. RESULTS: In the FLM group 2 cases were eliminated for not taking medication strictly according to the research plan and 1 case was lost to follow-up, while 2 cases in the acupuncture group and 2 cases in the combined therapy group were lost to follow-up. Compared with those detected pre-treat- ment, the defecation interval, stool property, consti- pation symptom grade, accompanying symptom grade, and GITT were all decreased markedly at the end of treatment in every group, while the MTL levels in serum and life quality score were increased markedly (P<0.01), the above-mentioned detecting indices were better in the combined therapy group than those in other groups (P<0.05). Compared with the end of treatment, above-mentioned detecting indices all recurred significantly in the FLM group and control group 60 weeks post-treatment (P>0.05), but these indices recurred insignificantly in the acupuncture and combined therapy groups (P>0.05). The short and long-term total effective rates in the combined therapy group were significantly different from those in other groups (P<0.05 or P<0.01). No serious adverse reactions were found in four groups. CONCLUSION: Both FLM and acupuncture can significantly shorten the defecation interval and GITT, increase MTL levels in serum, decrease the scores of stool property, constipation symptoms, and accompanying symptoms in patients with FC to increase their life quality. The combined therapy is much better in long-term efficacy and the safety is also good, worth spreading in clinical practice.展开更多
A highly pixelated and luminescent silica-coated quantum dot color filter(QDCF)was achieved by surface conjugation with epoxy functional group.Epoxy-functionalized silica-coated quantum dots(QDs)can be thoroughly mixe...A highly pixelated and luminescent silica-coated quantum dot color filter(QDCF)was achieved by surface conjugation with epoxy functional group.Epoxy-functionalized silica-coated quantum dots(QDs)can be thoroughly mixed with SU-8 photoresist up to 25 wt.%without aggregation.The quantum yield(QY)of the silica-coated QDCF can be significantly improved from 19.3%to 36.5%after epoxy treatment.The pristine QDCF experienced a 40%QY decrease,while the epoxied silica-coated QDCF maintained its luminescence even after irradiation(300 mW cm 2@450 nm)for over 25 days.The well-controlled epoxy cap plays a critical role in attaining the ideal optical properties of the QDCF.展开更多
We design a grey wolf optimizer hybridized with an interior point algorithm to correct a faulty antenna array. If a single sensor fails, the radiation power pattern of the entire array is disturbed in terms of sidelob...We design a grey wolf optimizer hybridized with an interior point algorithm to correct a faulty antenna array. If a single sensor fails, the radiation power pattern of the entire array is disturbed in terms of sidelobe level(SLL) and null depth level(NDL), and nulls are damaged and shifted from their original locations. All these issues can be solved by designing a new fitness function to reduce the error between the preferred and expected radiation power patterns and the null limitations. The hybrid algorithm has been designed to control the array's faulty radiation power pattern. Antenna arrays composed of 21 sensors are used in an example simulation scenario. The MATLAB simulation results confirm the good performance of the proposed method, compared with the existing methods in terms of SLL and NDL.展开更多
OBJECTIVE:To examine the clinical effects of a mixture of Chinese Yam and Epimedium in patients with stable moderate or severe chronic obstructive pulmonary disease(COPD).METHODS:Forty-nine patients with COPD were ran...OBJECTIVE:To examine the clinical effects of a mixture of Chinese Yam and Epimedium in patients with stable moderate or severe chronic obstructive pulmonary disease(COPD).METHODS:Forty-nine patients with COPD were randomly allocated to a group whose usual treatment was supplemented with oral Chinese Yam-Epimedium mixture,or a control group given placebo.For each patient,body mass index,airflow obstruction,dyspnea,and exercise capacity were measured and converted into the BODE index before treatment and at one and three months after initiation of treatment.Participants also completed the St George's Respiratory Questionnaire(SGRQ) at the same intervals.RESULTS:After one month,improvements were seen in the BODE index and SGRQ of participants taking Chinese Yam-Epimedium mixture compared to controls.There were statistically significant differences in the SGRQ:three of its components and the total SGRQ scores were significantly decreased(P<0.05),respiratory symptom scores had improved(P<0.01),and the dyspnea component of the BODE index had significantly decreased(P<0.05).Similar improvements were observed after three months of treatment,but exercise tolerance had also improved:the six-minute walking distance had significantly increased(P<0.05) in the treatment group when compared with controls.CONCLUSION:Chinese Yam-Epimedium mixture can significantly improve dyspnea,exercise capacity,and the quality of life of patients with stable moderate or severe COPD.展开更多
For a circular lobed nozzle with the exit plane displaced from the center body,adding a central plug at exit or replacing the nozzle with an alternating-lobe nozzle can improve the mixing effectiveness.In this study,n...For a circular lobed nozzle with the exit plane displaced from the center body,adding a central plug at exit or replacing the nozzle with an alternating-lobe nozzle can improve the mixing effectiveness.In this study,numerical investigations of jet mixing in the lobed nozzles with a central plug and alternating-lobe nozzles in pumping operation were conducted.The effects of the central plugs with the wake ranging from attached to separated flow on the mixing were analyzed,along with the mechanism of improving the mixing performance in a"sword"alternating-lobe nozzle.The simulation results reveal that the large-scale mixing rate,which is dominated by streamwise vortices,is related to the intensity of the attainable heat and mass transfer in the streamwise vortices.The effects of the streamwise vortices on the normal vortex ring are virtually a manifestation of the heat and mass transfer/mixing process of the streamwise vortices.The simulation results also show that the central plug with the attached rear-flow performs better in improving the mixing effectiveness and pumping performance;on the contrary,if the rear-flow is separated,more pressure loss will be induced.In particular,a completely separated flow over the rear of the central plug will severely degrade the attainable heat and mass transfer in the streamwise vortices.For the sword alternating-lobe nozzle,wider sword deep troughs help to increase the flux of the secondary stream around the core region and delay the confluence of the primary stream in the region between the deep and shallow troughs.Thus,the mixing is improved in the middle and posterior segments.Compared to the lobed nozzle with a central plug,the improved sword alternating-lobe nozzle can achieve a higher mixing effectiveness with much less pressure loss,which is preferred in situations when the power loss of the engine is restricted.展开更多
In this paper,we consider unusual event detection problem in a novel viewpoint and provide an algorithm to solve the problem.The actions or events in the scene is usual or not will eventually be reflected on the chang...In this paper,we consider unusual event detection problem in a novel viewpoint and provide an algorithm to solve the problem.The actions or events in the scene is usual or not will eventually be reflected on the changes of some basic features.We summarize these basic event features and propose special representation for each of them.Thus we can model these features in a uniform mode using adaptive Gaussian mixture model.Supervised and unsupervised unusual event detection algorithm can be designed to fit various situations based on this model.The superiority of our model is that it can detect unusual event automatically without to know the determinate model of unusual events.In conclusion,we provide two applications to verify the effectiveness of our model.展开更多
文摘Achieving optimal alignment in total knee arthroplasty(TKA)is a critical factor in ensuring optimal outcomes and long-term implant survival.Traditionally,mechanical alignment has been favored to achieve neutral post-operative joint alignment.However,contemporary approaches,such as kinematic alignments and hybrid techniques including adjusted mechanical,restricted kinematic,inverse kinematic,and functional alignments,are gaining attention for their ability to restore native joint kinematics and anatomical alignment,potentially leading to enhanced functional outcomes and greater patient satisfaction.The ongoing debate on optimal alignment strategies considers the following factors:long-term implant durability,functional improvement,and resolution of individual anatomical variations.Furthermore,advancements of computer-navigated and robotic-assisted surgery has augmented the precision in implant positioning and objective measurements of soft tissue balance.Despite ongoing debates on balancing implant longevity and functional outcomes,there is an increasing advocacy for personalized alignment strategies that are tailored to individual anatomical variations.This review evaluates the spectrum of various alignment techniques in TKA,including mechanical alignment,patient-specific kinematic approaches,and emerging hybrid methods.Each technique is scrutinized based on its fundamental principles,procedural techniques,inherent advantages,and potential limitations,while identifying significant clinical gaps that underscore the need for further investigation.
基金Supported by a grant from the National High Technology Research and Development Program of China (863 Program, No.2006AA010102)the National Natural Science Foundation of China (No.60872105).
文摘This paper presents an improved voice morphing algorithm based on Gaussian Mixture Model(GMM) which overcomes the traditional one in the terms of overly smoothed problems of the converted spectral and discontinuities between frames.Firstly, a maximum likelihood estimation for the model is introduced for the alleviation of the inversion of high dimension matrixes caused by traditional conversion function.Then, in order to resolve the two problems associated with the baseline, a codebook compensation technique and a time domain medial filter are applied.The results of listening evaluations show that the quality of the speech converted by the proposed method is significantly better than that by the traditional GMM method, and the Mean Opinion Score(MOS) of the converted speech is improved from 2.5 to 3.1 and ABX score from 38% to 75%.
文摘A new multifunctional testing device for rock fragmentation was introduced, which can conduct many experiments such as single cutting under static load, crushing under impact load, thrusting under static load and cutting-impact test under the dynamic and static load. The results of granite and concrete抯 experiments with polycrystalline diamond compact (PDC) flat cutters and carbide alloy cutters under different loadings show that the device has good performance, and the characteristics of broken rock under the combined loads are similar to that under the single static pressure or impact crushing the rock, and the combined loads can increase the effect of rock fragmentation obviously. The experimental methods and effects have the important meaning for studying new drill-ing tool on hard rock fragmentation.
基金supported in part by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2011-0004114)in part by the Ministry of Knowledge Economy (MKE) and Korea Institute for Advancement in Technology (KIAT) through the Workforce Development Program in Strategic Technology in part by the MKE (The Ministry of Knowledge Economy), Korea, under the CITRC (Convergence Information Technology Research Center) support program (NIPA-2012-C6150-1201-0001) supervised by the NIPA (National IT Industry Promotion Agency)
文摘A new method of prefetching data blocks from the NVCache to the page cache in main memory and cascading prefetching n-blocks from a hard disk to the NVCache together was proposed to reduce the spin-up frequency of a hybrid hard disk drive and thus enhance I/O performance.The proposed method consists of three steps:1) Analyzing the pattern of read requests in block units;2) Determining the number of blocks prefetched to the NVCache;3) Replacing blocks in the NVCache according to the block replacement policy.The proposed method can reduce the latency time of a hybrid hard disk and optimize the power consumption of an IPTV set-top box.Experimental results show that the proposed method provides better average response time compared to an existing adaptive multistream prefetching(AMP) method by 25.17%.It also reduces by 20.83% the average power consumption over that of the existing external caching in energy saving storage system(EXCES) method.
文摘The changes of several immune functions were observed in rats after they were inflicted with 6 Gy gamma rays irradiation, 15% TBSA full thickness brun and the combination of the 2 injuries. It was found that the functions of thymocytes and splenocytes suffered the most severe suppression in the 24th to 72nd hour after radiation injury and began to recover on the 7th day. In the rats with burn injury, the suppression on thymocytes and splenocytes were significantly less severe than that after radiation and recovered more rapidly. The effects of combined radiation-burn injury showed several characteristics. The suppression on the thymocytes was more severe with slower recovery as compared with that after single radiation injury only. The suppression on the splenocytes as a whole was similar to that after single radiation injury , but in the early stage after combined injury, the suppression was far more severe than that after radiation Escharectomy and skin grafting on the burn wounds on the lst day after combined injury could accelerate the recovery on both the thymocytes and splenocytes. Our findings indicated that the severity of the suppression on the immune functions due to combined radiation-burn injury might depend on the size of the burn wounds.
基金Project(60801053) supported by the National Natural Science Foundation of ChinaProject(4082025) supported by the Beijing Natural Science Foundation,China+4 种基金Project(20070004037) supported by the Doctoral Foundation of ChinaProject(2009JBM135,2011JBM023) supported by the Fundamental Research Funds for the Central Universities of ChinaProject(151139522) supported by the Hongguoyuan Innovative Talent Program of Beijing Jiaotong University,ChinaProject(YB20081000401) supported by the Beijing Excellent Doctoral Thesis Program,ChinaProject (2006CB303105) supported by the National Basic Research Program of China
文摘To improve motion graph based motion synthesis,semantic control was introduced.Hybrid motion features including both numerical and user-defined semantic relational features were extracted to encode the characteristic aspects contained in the character's poses of the given motion sequences.Motion templates were then automatically derived from the training motions for capturing the spatio-temporal characteristics of an entire given class of semantically related motions.The data streams of motion documents were automatically annotated with semantic motion class labels by matching their respective motion class templates.Finally,the semantic control was introduced into motion graph based human motion synthesis.Experiments of motion synthesis demonstrate the effectiveness of the approach which enables users higher level of semantically intuitive control and high quality in human motion synthesis from motion capture database.
基金Supported by the National Basic Research Program of China("973" Program,No.2012CB720500)the National Natural Science Foundation of China(No.21176171)
文摘An approach was presented to intensify the mixing process. Firstly, a novel concept, the dissipation of mass transfer ability(DMA) associated with convective mass transfer, was defined via an analogy to the heat-work conversion. Accordingly, the focus on mass transfer enhancement can be shifted to seek the extremum of the DMA of the system. To this end, an optimization principle was proposed. A mathematical model was then developed to formulate the optimization into a variational problem. Subsequently, the intensification of the mixing process for a gas mixture in a micro-tube was provided to demonstrate the proposed principle. In the demonstration example, an optimized velocity field was obtained in which the mixing ability was improved, i.e., the mixing process should be intensified by adjusting the velocity field in related equipment. Therefore, a specific procedure was provided to produce a mixer with geometric irregularities associated with an ideal velocity.
文摘Chromate and dichromate sodium as a function of oxidizer characteristics are used in several industrial areas; for example, in surface protection of coated parts of cadmium, zinc and aluminum (chromate coated treated), corrosion inhibitors, the treatment of leather, the manufacture of pigments, etc. However, the use of such products has been questioned due to the problems of toxicity and pollution that can be caused in the environmental. The Brazilian environmental agency has established that the concentrations of chromate in water courses are less than 0.5 ppm. In order to reuse chromate (CrO42) from industrial effluent, laboratory experiments have been proposed based on chemical reduction or electrolytic processes, in order to transform these chromate ions in a final mix of oxides (in solid form), which can then be packed and sent to the production process of sodium chromate. The results of these experiments have become useful industrially (without regard to costs) considering the environmental reuse and the life cycle of the chemical compound.
文摘OBJECTIVE: To explore the short and long-term efficacy of combining Fuzhengliqi mixture (FLM) with acupuncture in treating functional constipation (FC). METHODS: The 560 patients with confirmed diagnosis of FC were randomly assigned to four groups: FLM group, acupuncture group, combined therapy group, and control group. There were 140 cases in each group. The FLM group was administered FLM 60 mL twice a day, while the acupuncture group was treated with acupuncture at acupoints Tianshu (ST 25), Shangjuxu (ST 37), Zusanli (ST 36), Dachangshu (BL 25), and Zhigou (TE 6) twice a day, the combined therapy group with FLM and acupuncture, and the control group was administered mosapride (5 mg thrice a day) and Macrogol 4000 (10 g twice a day). The treatment lasted 6 weeks. The defecation interval, stool property, constipation symptoms, and accompanying symptomswere recorded, graded, and scored.The gastrointestinal transit time (GITT) and motilin (MTL) level in serum and life quality score were detected at three time points (pre-treatment, at the end of treatment, and 60 weeks post-treatment). Moreover, the adverse reactions were also observed. RESULTS: In the FLM group 2 cases were eliminated for not taking medication strictly according to the research plan and 1 case was lost to follow-up, while 2 cases in the acupuncture group and 2 cases in the combined therapy group were lost to follow-up. Compared with those detected pre-treat- ment, the defecation interval, stool property, consti- pation symptom grade, accompanying symptom grade, and GITT were all decreased markedly at the end of treatment in every group, while the MTL levels in serum and life quality score were increased markedly (P<0.01), the above-mentioned detecting indices were better in the combined therapy group than those in other groups (P<0.05). Compared with the end of treatment, above-mentioned detecting indices all recurred significantly in the FLM group and control group 60 weeks post-treatment (P>0.05), but these indices recurred insignificantly in the acupuncture and combined therapy groups (P>0.05). The short and long-term total effective rates in the combined therapy group were significantly different from those in other groups (P<0.05 or P<0.01). No serious adverse reactions were found in four groups. CONCLUSION: Both FLM and acupuncture can significantly shorten the defecation interval and GITT, increase MTL levels in serum, decrease the scores of stool property, constipation symptoms, and accompanying symptoms in patients with FC to increase their life quality. The combined therapy is much better in long-term efficacy and the safety is also good, worth spreading in clinical practice.
基金supported by the National Key Research and Development Program of China administrated by the Ministry of Science and Technology of China(2016YFB0401702)the National Natural Science Foundation of China(61674074,61704072 and61405089)+11 种基金Shenzhen Innovation Project(JCYJ20160301113537474)Shenzhen Basic Research Project(JCYJ20170817112012493)Development and Reform Commission of Shenzhen Project([2017]1395)Shenzhen Peacock Team Project(KQTD2016030111203005)Shenzhen Key Laboratory for Advanced Quantum Dot Displays and Lighting(ZDSYS201707281632549)Guangdong University Key Laboratory for Advanced Quantum Dot Displays and Lighting(2017KSYS007)Distinguished Young Scholar of National Natural Science Foundation of Guangdong(2017B030306010)Tianjin Zhonghuan Quantum Tech Co.,Ltd.(18YFZCGX00580)the start-up fund from Southern University of Science and Technologysupported by the Pico Center at SUSTech that received support from Presidential fundDevelopment and Reform Commission of Shenzhen MunicipalityChina Postdoctoral Science Foundation Grant(2018M631443)
文摘A highly pixelated and luminescent silica-coated quantum dot color filter(QDCF)was achieved by surface conjugation with epoxy functional group.Epoxy-functionalized silica-coated quantum dots(QDs)can be thoroughly mixed with SU-8 photoresist up to 25 wt.%without aggregation.The quantum yield(QY)of the silica-coated QDCF can be significantly improved from 19.3%to 36.5%after epoxy treatment.The pristine QDCF experienced a 40%QY decrease,while the epoxied silica-coated QDCF maintained its luminescence even after irradiation(300 mW cm 2@450 nm)for over 25 days.The well-controlled epoxy cap plays a critical role in attaining the ideal optical properties of the QDCF.
基金supported by the Ministry of Higher Education(MOHE)the Research Management Centre(RMC)+2 种基金the School of Postgraduate Studies(SPS)the Communication Engineering Department,the Faculty of Electrical Engineering(FKE)Universiti T¨ekùnolóogi Malaysia(UTM)Johor Bahru(Nos.12H09 and 03E20tan)
文摘We design a grey wolf optimizer hybridized with an interior point algorithm to correct a faulty antenna array. If a single sensor fails, the radiation power pattern of the entire array is disturbed in terms of sidelobe level(SLL) and null depth level(NDL), and nulls are damaged and shifted from their original locations. All these issues can be solved by designing a new fitness function to reduce the error between the preferred and expected radiation power patterns and the null limitations. The hybrid algorithm has been designed to control the array's faulty radiation power pattern. Antenna arrays composed of 21 sensors are used in an example simulation scenario. The MATLAB simulation results confirm the good performance of the proposed method, compared with the existing methods in terms of SLL and NDL.
文摘OBJECTIVE:To examine the clinical effects of a mixture of Chinese Yam and Epimedium in patients with stable moderate or severe chronic obstructive pulmonary disease(COPD).METHODS:Forty-nine patients with COPD were randomly allocated to a group whose usual treatment was supplemented with oral Chinese Yam-Epimedium mixture,or a control group given placebo.For each patient,body mass index,airflow obstruction,dyspnea,and exercise capacity were measured and converted into the BODE index before treatment and at one and three months after initiation of treatment.Participants also completed the St George's Respiratory Questionnaire(SGRQ) at the same intervals.RESULTS:After one month,improvements were seen in the BODE index and SGRQ of participants taking Chinese Yam-Epimedium mixture compared to controls.There were statistically significant differences in the SGRQ:three of its components and the total SGRQ scores were significantly decreased(P<0.05),respiratory symptom scores had improved(P<0.01),and the dyspnea component of the BODE index had significantly decreased(P<0.05).Similar improvements were observed after three months of treatment,but exercise tolerance had also improved:the six-minute walking distance had significantly increased(P<0.05) in the treatment group when compared with controls.CONCLUSION:Chinese Yam-Epimedium mixture can significantly improve dyspnea,exercise capacity,and the quality of life of patients with stable moderate or severe COPD.
基金supported by the Assembly Research Foundation of China
文摘For a circular lobed nozzle with the exit plane displaced from the center body,adding a central plug at exit or replacing the nozzle with an alternating-lobe nozzle can improve the mixing effectiveness.In this study,numerical investigations of jet mixing in the lobed nozzles with a central plug and alternating-lobe nozzles in pumping operation were conducted.The effects of the central plugs with the wake ranging from attached to separated flow on the mixing were analyzed,along with the mechanism of improving the mixing performance in a"sword"alternating-lobe nozzle.The simulation results reveal that the large-scale mixing rate,which is dominated by streamwise vortices,is related to the intensity of the attainable heat and mass transfer in the streamwise vortices.The effects of the streamwise vortices on the normal vortex ring are virtually a manifestation of the heat and mass transfer/mixing process of the streamwise vortices.The simulation results also show that the central plug with the attached rear-flow performs better in improving the mixing effectiveness and pumping performance;on the contrary,if the rear-flow is separated,more pressure loss will be induced.In particular,a completely separated flow over the rear of the central plug will severely degrade the attainable heat and mass transfer in the streamwise vortices.For the sword alternating-lobe nozzle,wider sword deep troughs help to increase the flux of the secondary stream around the core region and delay the confluence of the primary stream in the region between the deep and shallow troughs.Thus,the mixing is improved in the middle and posterior segments.Compared to the lobed nozzle with a central plug,the improved sword alternating-lobe nozzle can achieve a higher mixing effectiveness with much less pressure loss,which is preferred in situations when the power loss of the engine is restricted.
基金the National Natural Science Foundation of China (No. 60805001)
文摘In this paper,we consider unusual event detection problem in a novel viewpoint and provide an algorithm to solve the problem.The actions or events in the scene is usual or not will eventually be reflected on the changes of some basic features.We summarize these basic event features and propose special representation for each of them.Thus we can model these features in a uniform mode using adaptive Gaussian mixture model.Supervised and unsupervised unusual event detection algorithm can be designed to fit various situations based on this model.The superiority of our model is that it can detect unusual event automatically without to know the determinate model of unusual events.In conclusion,we provide two applications to verify the effectiveness of our model.