试论企业“渠道”营销的风险及对策

企业营销具有很大风险，其中“渠道”营销是出现问题最多的一个环节，这个难题对企业的发展运行起到很大影响，“渠道”营销的成功与否关系到产品市场竞争的成败。本文通过解析“渠道”营销风险具有的重要性，分析“渠道”营销风险出现问题的原因，并探索解决问题的有效对策。

媒体融合中再论“内容”和“渠道”

新媒体时代,媒体融合是当下所有媒体单位都在思考的课题,除了技术和平台的打造,媒体本身的内容生产和渠道建设也是重中之重。在这个时代,只重"渠道为王"显然不妥,但只提"内容为王"似乎也行不通,传统纸媒该如何抉择?如果能把"渠道建设""内容建设""用户思维""优质运营"四者结合起来,传统媒体的这一场革命或许就能走上康庄大道。

客观认识和定位“渠道扁平化”

目前,企业界有盲目迷信“渠道扁平化”而忽视“深度分销”等有效渠道技术的倾向,对企业行为形成误导。本文提出,“渠道扁平化”是一种趋势,客观上它能够提高渠道效率和效益,但在当今中国,渠道的“扁平化”存在诸多可能的误区和应用局限,“深度分销”仍是一种必然。企业应该“顺势而为”,综合运用各种渠道技术,树立科学、辩证的渠道观,才能保证企业分销工作持续、健康的发展。

“家电下乡”活动的分销渠道建设思考——以湖北省为例

该文在全国开展的"家电下乡"活动的背景下,以湖北省为例,认为农村家电市场消费具有注重经济实用性、消费时间集中、市场分布广、品牌意识逐渐增强等特征,预测了活动持续期间农村家电市场的需求,对目前较成熟的区域代理分销模式、大型连锁终端分销模式、企业自建渠道分销模式、直销模式等四种家电产品分销渠道进行了分析,并给出了针对农村市场的分销渠道创新建议。

“渠道精耕”在电信运营商渠道管理中的应用

1 电信市场销售渠道现状 长期以来,由于电信垄断的特点,我国电信运营企业一直采用“用户申请-运营商安装”的直销方式。

2004年——广东邮政的“渠道建设年”

广东省邮政局党组将2004年确定为全省邮政的"渠道建设年",动员全省各级邮政对明年和后五年的工作早思考、早谋划、早运作,努力"疏通"制约市场业务拓展的"渠道",使邮政的资源优势、市场优势和业务拓展优势得到更好地发挥。

Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarclnoma

There is evidence to suggest that follicle-stimulating hormone （FSH） can facilitate the neovascularization of ovarian cancers by increasing vascular endothelial growth factor （VEGF） expression in cancer cells, although the underlying molecular mechanism of this process is not well known. Therefore, we investigated the effect of FSH on VEGF expression in the ovarian cancer cell lines SKOV-3 and ES-2. Treatment with FSH significantly increased VEGF expression in a dose- and time-dependent manner. In addition, FSH treatment enhanced the expression of survivin and hypoxlainducible factor-1 （HIF-1α）. Knockdown of survivin or HIF-1α suppressed VEGF expression, but only knockdown of survivin inhibited FSH-stimulated VEGF expression. Pretreatment with LY294002, a phosphoinositide 3-kinase （PI3K）/AKT inhibitor, neutralized the enhanced expression of survivin induced by FSH, but treatment with U0126, a mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor, had no such effect. We further showed that ovarian serous cystadenocarcinoma samples had much higher incidence of positive AKT and phosphorylated AKT （pAKT） protein staining than did benign ovarian cystadenoma samples （p 〈 0.01）. The 5-year survival rate was only about 15% in patients with ovarian serous cystadenocarcinoma who had AKT and pAKT expression, whereas it was about 80% in those who did not have AKT or pAKT expression. Taken together, these results indicate that FSH increases the expression of VEGF by upregulating the expression of survivin, which is activated by the PI3K/AKT signaling pathway. Understanding the role of the PI3K/AKT pathway in FSH-stimulated expression of survivin and VEGF will be beneficial for evaluating the prognosis for patients with ovarian serous cystadenocarcinoma and for pursulug effective treatment against this disease.

Calcium signaling and T-type calcium channels in cancer cell cycling

Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is essential for cells to enter and accomplish the S phase and the M phase of the cell cycle. In contrast, cancerous cells can pass these phases of the cell cycle with much lower cytoplasmic free calcium concentrations, indicating an alternative mechanism has developed for fulfilling the intracellular calcium requirement for an increased rate of DNA synthesis and mitosis of fast replicating cancerous cells. The detailed mechanism underlying the altered calcium loading pathway remains unclear; however, there is a growing body of evidence that suggests the T-type Ca2+ channel is abnormally expressed in cancerous cells and that blockade of these channels may reduce cell proliferation in addition to inducing apoptosis. Recent studies also show that the expression of T-type Ca2+ channels in breast cancer cells is proliferation state dependent, i.e. the channels are expressed at higher levels during the fast-replication period, and once the cells are in a non-proliferation state, expression of this channel isminimal. Therefore, selectively blocking calcium entry into cancerous cells may be a valuable approach for preventing tumor growth. Since T-type Ca2+ channels are not expressed in epithelial cells, selective T-type Ca2+ channel blockers may be useful in the treatment of certain types of cancers.

Centrifugal and field studies on water infiltration characteristics below canals under wetting-drying-freezing-thawing cycles

Seepage is one of the main causes for the deformation and instability of canal slopes in Xinjiang,China.In this study,centrifugal model tests under wetting-drying(WD)and wetting-drying-freezing-thawing(WDFT)cycles were performed to investigate the water infiltration characteristics below a canal.The results show that the shallow soil of the canal models was fully saturated in the wetting process.Compared with the canal model under the WD cycles,the canal model under the WDFT cycles had larger saturated areas and a higher degree of saturation below the canal top after each cycle,indicating that the freezing-thawing(FT)process in the WDFT cycles promoted the water infiltration behavior below the canal slope.The cracks on the surface of the canal model under the cyclic action of WDFT developed further and had a higher connectivity,which provided the conditions for slope instability from a transverse tensile crack running through the canal top.On this basis,a field test was conducted to understand the water infiltration distribution below a typical canal in Xinjiang,China,which also verified the accuracy of the centrifugal results.This study provides a preliminary basis for the maintenance and seepage treatment of canals in Xinjiang,China.

UWB channel modeling for indoor line-of-sight environment

SV/IEEE 802.15.3a model has been the standard model for Ultra-wide bandwidth (UWB) indoor non-line-of-sight (NLOS) wireless propagation,but for line-of-sight (LOS) case,it is not well defined. In this paper,a new statistical distribution model exclusively used for LOS environment is proposed based on investigation of the experimental data. By reducing the number of the visible random arriving clusters,the model itself and the parameters estimating of the corresponding model are simplified in comparison with SV/IEEE 802.15.3a model. The simulation result indicates that the proposed model is more accurate in modeling small-scale LOS environment than SV/IEEE 802.15.3a model when considering cumulative distribution functions (CDFs) for the three key channel impulse response (CIR) statistics.

Characteristics of transmitting channel wave in a coal seam

An embedded underground coal seam carries channel waves of low seismic velocity along a stratigraphic rock-coal-rock sequence.In a homogeneous and isotropic seam, seismic waves propagate as trapped waves within the seam, which leads to propagation of channel waves.We describe how to set up a field test for transmission in order to acquire channel waves in a coal seam.Because channel wave signals are non-stationary in their frequencies and amplitudes, a necessary velocity spectrum and wavelet transformation analysis are applied to interpret the characteristics of channel waves.The advantage of using a wavelet transformation is that different resolutions can be obtained at different times and different frequencies.According to analysis of the seismic signals acquired in the S7 sensor hole, it was clearly shown that the characteristics of channel waves are lower frequencies and attenuation which can guide an effective wave for detecting voids, boundaries and faults in coal seams with strong roofs and floors.

On the structural features of fiber suspensions in converging channel flow

The structural features of fiber suspensions are dependent on the fiber alignment in the flows. In this work the orientation distribution function and orientation tensors for semi-concentrated fiber suspensions in converging channel flow were calculated, and the evolutions of the fiber alignment and the bulk effective vis-cosity were analyzed. The results showed that the bulk stress and the effective viscosity were functions of therate-of-strain tensor and the fiber orientation state ; and that the fiber suspensions evolved to steady alignment and tended to concentrate to some preferred directions close to but not same as the directions of local stream-lines. The bulk effective viscosity depended on the product of Reynolds number and time. The decrease of ef-fective viscosity near the boundary benefited the increase of the rate of flow. Finally when the fiber alignment went into steady state, the structural features of fiber suspensions were not dependent on the Reynolds numberbut on the converging channel angle.

Tripartite Arbitrary Two-Qutrit Quantum State Sharing

A tripartite scheme for securely sharing an arbitrary unknown two-qutrit state is proposed, where two generalized Greenberger-Horne-Zeilinger （GHZ） states serve as the quantum channel linking the three legitimate parties. The quantum information （i.e., the arbitrary unknown two-qutrit state） from the sender can be split in such a way that it can be reconstructed deterministically by any agent via a proper unitary operation provided that both agents collaborates together. Moreover, the generalization of the tripartite scheme to more-party case is also outlined.

Analysis of microscopic pore structures of rocks before and after water absorption

Hydrophilic characteristics of rocks are affected by their microscopic pore structures,which clearly change after water absorption.Water absorption tests and scanning electron microscopic（SEM） experiments on rock samples,located at a site in Tibet,China,were carried out Changes of rock pore structures before and after water absorption were studied with the distribution of pore sizes and fractal characteristics of pores.The results show that surface porosities,fractal dimensions of pores and the complexity of pore structures increased because the number of new small pores produced increased or the original macropore flow channels were expanded after rocks absorbed water.There were points of inflection on their water absorption curves.After water absorption of other rocks,surface porosities and fractal dimensions of pores and complexity of pore structures decreased as the original pore flow channels became filled.Water absorption curves did not change.Surface porosity and the pore fractal dimensions of rocks have good linear relationships before and after water absorption.

Single channel blind source separation based on ICA feature extraction

A new technique is proposed to solve the blind source separation (BSS) given only a single channel observation. The basis functions and the density of the coefficients of source signals learned by ICA are used as the prior knowledge. Based on the learned prior information the learning rules of single channel BSS are presented by maximizing the joint log likelihood of the mixed sources to obtain source signals from single observation, in which the posterior density of the given measurements is maximized. The experimental results exhibit a successful separation performance for mixtures of speech and music signals.

Placement of percutaneous transhepatic biliary stent using a silicone drain with channels

This report describes a method for percutaneous transhepatic biliary stenting with a BLAKE Silicone Drain, and discusses the usefulness of placement of the drain connected to a J-VAC Suction Reservoir for the treatment of stenotic hepaticojejunostomy. Percutaneous transhepatic biliary drainage was performed under ultrasonographic guidance in a patient with stenotic hepaticojejunostomy after hepatectomy for hepatic hilum malignancy. The technique used was as follows. After dilatation of the drainage root, an 11-FF tube with several side holes was passed through the stenosis of the hepaticojejunostomy. A 10-Fr BLAKE Silicone Drain is flexible, which precludes onestep insertion. One week after insertion of the 11-Fr tube, a 0.035-inch guidewire was inserted into the tube. After removal of the 11-Fr tube, the guidewire was put into the channel of a 10-Fr BLAKE Silicone Drain. The drain was inserted into the jejunal limb through the intrahepatic bile duct and was connected to a J-VAC Suction Reservoir. Low-pressure continued suction was applied. Patients can be discharged after insertion of the 10-Fr BLAKE Silicone Drain connected to the J-VAC Suction Reservoir. Placement of a percutaneous transhepaUc biliary stent using a 10-Fr BLAKE Silicone Drain connected to a J-VAC Suction Reservoir is useful for the treatment of stenotic hepaticojejunostomy.

Design of a multi-channel free space optical interconnection component

A multi-channel free space optical interconnection component, fiber optic rotary joint, was designed using a Dove prism. When the Dove prism is rotated an angle of at around the longitudinal axis, the image rotates an angle of 2 at. The optical interconnection component consists of the signal transmission system, Dove prim and driving mechanism. The planetary gears are used to achieve the speed ratio of 2：l between the total optical interconnection component and the Dove prism. The Clenses are employed to couple different optical signals in the signal transmission system. The coupling loss between the receiving fiber of stationary part and the transmitting fiber of rotary part is measured.

Revisiting Controlled Quantum Secure Direct Communication Using a Non-symmetric Quantum Channel with Quantum Superdense Coding

Recently Xia and Song [Phys. Lett. A 364 （2007） 117] have proposed a controlled quantum secure direct communication （CQSDC） protocol. They claimed that in their protocol only with the help of the controller Charlie, the receiver Alice can successfully extract the secret message from the sender Bob. In this letter, first we will show that within their protocol the controller Charlie＇s role could have been excluded if it were not for their unreasonable design. We then revise the Xia-Song CQSDC protocol such that its original advantages are reta/ned and the CQSDC can be really realized.

Entanglement Dynamics of Two-Qubit System in Different Types of Noisy Channels

In this paper, we study entanglement dynamics of a two-qubit extended Werner-like state locally, interacting with independent noisy channels, i.e., amplitude damping, phase damping, and depolarizing channels. We show that the purity of initial entangled state has direct impacts on the entanglement robustness in each noisy channel. That is, if the initial entangled state is prepared in mixed instead of pure form, the state may exhibit entanglement sudden death （ESD） and/or be decreased for the critical probability at which the entanglement disappear.