In this paper, based on a class of multi-group epidemic models of SEIR type with bilinear incidences, we introduce a vaccination compartment, leading to multi-group SVEIR model. We establish that the global dynamics a...In this paper, based on a class of multi-group epidemic models of SEIR type with bilinear incidences, we introduce a vaccination compartment, leading to multi-group SVEIR model. We establish that the global dynamics are completely determined by the basic reproduction number R0V which is defined by the spectral radius of the next generation matrix. Our proofs of global stability of the equilibria utilize a graph-theoretical approach to the method of Lyapunov functionals. Mathematical results suggest that vaccination is helpful for disease control by decreasing the basic reproduction number. However, there is a necessary condition for successful elimination of disease. If the time for the vaccines to obtain immunity or the possibility for them to be infected before acquiring immunity is neglected in each group, this condition will be satisfied and the disease can always be eradicated by suitable vaccination strategies. This may lead to over evaluation for the effect of vaccination.展开更多
In this paper, the global properties of a mathematical modeling of hepatitis C virus （HCV） with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability o...In this paper, the global properties of a mathematical modeling of hepatitis C virus （HCV） with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability of the uninfected and infected steady states. It is shown that if the basic reproduction number R0 is less than unity, then the uninfected steady state is globally asymptotically stable. If the basic reproduction number R0 is larger than unity, then the infected steady state is globally asymptotically stable.展开更多
An epidemic model with a class of nonlinear incidence rates and distributed delay is analyzed. The nonlinear incidence is used to describe the saturated or the psychological effect of certain serious epidemics on the ...An epidemic model with a class of nonlinear incidence rates and distributed delay is analyzed. The nonlinear incidence is used to describe the saturated or the psychological effect of certain serious epidemics on the community when the number of infectives is getting larger. The distributed delay is derived to describe the dynamics of infectious diseases with varying immunity. Lyapunov functionals are used to show that the diseasefree equilibrium state is globally asymptotically stable when the basic reproduction number is less than or equal to one. Moreover, it is shown that the disease is permanent if the basic reproduction number is greater than one. Furthermore, the sufficient conditions under which the endemic equilibrium is locally and globally asymptotically stable are obtained.展开更多
文摘In this paper, based on a class of multi-group epidemic models of SEIR type with bilinear incidences, we introduce a vaccination compartment, leading to multi-group SVEIR model. We establish that the global dynamics are completely determined by the basic reproduction number R0V which is defined by the spectral radius of the next generation matrix. Our proofs of global stability of the equilibria utilize a graph-theoretical approach to the method of Lyapunov functionals. Mathematical results suggest that vaccination is helpful for disease control by decreasing the basic reproduction number. However, there is a necessary condition for successful elimination of disease. If the time for the vaccines to obtain immunity or the possibility for them to be infected before acquiring immunity is neglected in each group, this condition will be satisfied and the disease can always be eradicated by suitable vaccination strategies. This may lead to over evaluation for the effect of vaccination.
文摘In this paper, the global properties of a mathematical modeling of hepatitis C virus （HCV） with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability of the uninfected and infected steady states. It is shown that if the basic reproduction number R0 is less than unity, then the uninfected steady state is globally asymptotically stable. If the basic reproduction number R0 is larger than unity, then the infected steady state is globally asymptotically stable.
文摘An epidemic model with a class of nonlinear incidence rates and distributed delay is analyzed. The nonlinear incidence is used to describe the saturated or the psychological effect of certain serious epidemics on the community when the number of infectives is getting larger. The distributed delay is derived to describe the dynamics of infectious diseases with varying immunity. Lyapunov functionals are used to show that the diseasefree equilibrium state is globally asymptotically stable when the basic reproduction number is less than or equal to one. Moreover, it is shown that the disease is permanent if the basic reproduction number is greater than one. Furthermore, the sufficient conditions under which the endemic equilibrium is locally and globally asymptotically stable are obtained.
