The transfer of pressurized water reactor(PWR)technology from France to China is an important event in the history of Sino-French scientific and technological relations.China has gradually achieved self-reliance in th...The transfer of pressurized water reactor(PWR)technology from France to China is an important event in the history of Sino-French scientific and technological relations.China has gradually achieved self-reliance in the field of PWR technology through the introduction and subsequent absorption of France's 900 MW reactors.Compared with the process of introducing and absorbing similar technology from the United States by France,China's experience has been more complicated.This circumstance reflects the differences in the nuclear power technology systems between the two countries.France's industrial strength and early acquisition of nuclear power technology laid a solid foundation for mastering PWR technology.On the other hand,although China established a weak foundation through the implementation of the"728 Project,"and tried hard to negotiate with France,the substantive content of the technology transfer was very limited.By way of the policy transition from"unhooking of technology and trade"to"integration of technology and trade,"China ultimately accomplished the absorption and innovation of PWR technology through the Ling'ao NPP.展开更多
Loess soils are widely distributed worldwide and typical in northwest China,and excessive agricultural irrigation has caused landslides in the area,specifi cally in the Heifangtai loess region in Lanzhou,Gansu,China.G...Loess soils are widely distributed worldwide and typical in northwest China,and excessive agricultural irrigation has caused landslides in the area,specifi cally in the Heifangtai loess region in Lanzhou,Gansu,China.Geophysical exploration is an essential method in landslide engineering geological surveys,and geological surveying,drilling,geophysical prospecting,monitoring,and other methods are used for performing engineering geological evaluation and obtaining comprehensive basic data for landslide protection design and construction.The theoretical feasibility of using geophysical methods in loess landslide detection is essential.On the basis of the shallow geological structure of the Heifangtai landslide region in Lanzhou,Gansu,China,a typical geoelectric model of the magnetotelluric method was established,and the loess landslide area was modeled through a two-dimensional fi nite element method,forward numerical simulation,and engineering geological analysis.The distribution characteristics of the magnetotelluric field were determined.This is a typical application of the geological process analysis method in geophysical exploration.This study provides the typical stratigraphic structure and electrical characteristics of different groundwater distributions in Heifangtai,Gansu,China,verifi es the accuracy of forward modeling and calculation results,and provides a detailed theoretical basis for landslide detection through magnetotelluric methods.Through the numerical simulation of the forward modeling of the Heifangtai landslide region in Lanzhou,Gansu,China,this study can provide a detailed geophysical basis for landslide investigation,corroborate results of geological investigation and landslide design,and facilitate the sustainable development of agriculture in Heifangtai.展开更多
A wide range of terrain features and landforms,which are exemplified by intricate geological formations and diverse rock compositions,are found in the western mountainous regions of China.These areas frequently encoun...A wide range of terrain features and landforms,which are exemplified by intricate geological formations and diverse rock compositions,are found in the western mountainous regions of China.These areas frequently encounter geological disasters.As one of the natural disasters,landslides lead to considerable loss of human life and property.Considering mitigation of the losses caused by landslide disasters,a necessary measure for disaster prevention and mitigation involves conducting detailed investigations and monitoring of landslides,which is also the cornerstone of landslide warning.This study compares and analyzes the feasibility of the magnetotelluric detection method for landslides using the results of engineering geological surveys and landslide monitoring.The study aims to address the scientific problem of the validity of using magnetotelluric methods to detect landslide development processes.The Tangjiawan landslide signal on the left side of the K94+000~K94+145 section of the Wenma Expressway is analyzed by employing engineering geological survey,magnetotelluric detection,landslide monitoring,landslide analysis,and other methods.Analysis results provide the static electrical characteristics of lithology,structure,and groundwater,as well as the dynamic electrical characteristics of landslide development.This study focuses on analyzing the relationship between the methods of magnetotelluric detection and engineering geological surveys and the results of landslide monitoring.The workflow and methods for data collection,processing,inversion,interpretation,and analysis using the magnetotelluric method to detect the dynamic development process of landslides are presented in the conclusion.Preliminary conclusions indicate a strong correlation between the dynamic changes in magnetotelluric wave impedance with the surface displacement of landslides and the dynamic changes in groundwater.The use of the magnetotelluric method for landslide detection and monitoring is a feasible example.The research results can offer certain technical references for the detection and monitoring of landslides using magnetotelluric methods and also provide references and guidance for the selection of diversified landslide monitoring methods in the future.展开更多
Economic development around the Daya Bay, China has profoundly affected the marine environment in the bay area in recent years, particularly since the operation of Daya Bay Nuclear Power Station （DNPS） in 1994. This...Economic development around the Daya Bay, China has profoundly affected the marine environment in the bay area in recent years, particularly since the operation of Daya Bay Nuclear Power Station （DNPS） in 1994. This study analyzed the changes of water temperature and harmful algal blooms （HABs） for two periods： 1983-1993 and 1994-2004, using in situ and satellite data. Results showed that yearly mean surface water temperature （SWT） and Chl-a concentration （Chl-a） increased by 1.1 ℃ and 1.9 mg/m^3, respectively, after 1994. The monthly occurrence of HAB was found to have increased also. HABs appeared only in spring and autumn before 1994, but occurred all the year round after 1994. SWT, Chl-a and HABs all increased significantly in May. Those changes were associated with environmental changes in this area, such as thermal discharge from the DNPS and enhancement of eutrophication from human activities around the Daya Bay.展开更多
Based on the analysis of the conjugate gradient algorithm, we implement a threedimensional （3D） conjugate gradient inversion algorithm with magnetotelluric impedance data. During the inversion process, the 3D conjug...Based on the analysis of the conjugate gradient algorithm, we implement a threedimensional （3D） conjugate gradient inversion algorithm with magnetotelluric impedance data. During the inversion process, the 3D conjugate gradient inversion algorithm doesn＇ t need to compute and store the Jacobian matrix but directly updates the model from the computation of the Jacobian matrix. Requiring only one forward and four pseudo-forward modeling applications per frequency to produce the model update at each iteration, this algorithm efficiently reduces the computation of the inversion. From a trial inversion with synthetic magnetotelluric data, the validity and stability of the 3D conjugate gradient inversion algorithm is verified.展开更多
Novel schemes for a charge sensitive amplifier （CSA） and a CR-（RC）, semi-Gaussian shaper in a fully integrated CMOS readout circuit for particle detectors are presented. The CSA is designed with poly-resistors as ...Novel schemes for a charge sensitive amplifier （CSA） and a CR-（RC）, semi-Gaussian shaper in a fully integrated CMOS readout circuit for particle detectors are presented. The CSA is designed with poly-resistors as feedback components to reduce noise. Compared with conventional CSA, the input referred equivalent noise charge（ENC） is simulated to be reduced from 5036e to 2381e with a large detector capacitance of 150pF at the cost of 0.5V output swing loss. The CR-（RC）,semi-Gaussian shaper uses MOS transistors in the triode region in series with poly-resistors to compensate process variation without much linearity reduction.展开更多
Scalar CSAMT is only suitable for measurements in one and two dimensions perpendicular to geological structures. For complex 3D geoelectric structure, tensor CSAMT is more suitable. In this paper, we discuss 3D tensor...Scalar CSAMT is only suitable for measurements in one and two dimensions perpendicular to geological structures. For complex 3D geoelectric structure, tensor CSAMT is more suitable. In this paper, we discuss 3D tensor CSAMT forward modeling using the vector finite-element method. To verify the feasibility of the algorithm, we calculate the electric field, magnetic field, and tensor impedance of the 3D CSAMT far-zone field in layered media and compare them with theoretical solutions. In addition, a three-dimensional anomaly in half-space is also simulated, and the response characteristics of the impedance tensor and the apparent resistivity and impedance phase are analyzed. The results suggest that the vector finite-element method produces high-precision electromagnetic field and impedance tensor data, satisfies the electric field discontinuity, and does not require divergence correction using the vector finite-element method.展开更多
A monolithic integrated CMOS preamplifier is presented for neural recording applications. Two AC-coupied capacitors are used to eliminate the large and random DC offsets existing in the electrode-electrolyte interface...A monolithic integrated CMOS preamplifier is presented for neural recording applications. Two AC-coupied capacitors are used to eliminate the large and random DC offsets existing in the electrode-electrolyte interface. Diode-connected nMOS transistors with a negative voltage between the gate and source are candidates for the large resistors necessary for the preamplifier. A novel analysis is given to determine the noise power spectral density. Simulation results show that the two-stage CMOS preamplifier in a closed-loop capacitive feedback configuration provides an AC in-band gain of 38.8dB,a DC gain of 0,and an input-referred noise of 277nVmax, integrated from 0. 1Hz to 1kHz. The preamplifier can eliminate the DC offset voltage and has low input-referred noise by novel circuit configuration and theoretical analysis.展开更多
We implement a parallel algorithm with the advantage of MPI （Message Passing Interface） to speed up the rapid relaxation inversion for 3D magnetotelluric data. We test the parallel rapid relaxation algorithm with sy...We implement a parallel algorithm with the advantage of MPI （Message Passing Interface） to speed up the rapid relaxation inversion for 3D magnetotelluric data. We test the parallel rapid relaxation algorithm with synthetic and real data. The execution efficiency of the algorithm for several different situations is also compared. The results indicate that the parallel rapid relaxation algorithm for 3D magnetotelluric inversion is effective. This parallel algorithm implemented on a common PC promotes the practical application of 3D magnetotelluric inversion and can be suitable for the other geophysical 3D modeling and inversion.展开更多
Aim To investigate the synergistic effect of the combination of pinellia total alkaloid （PTA） and uncaria total alkaloid （UTA）, and explore the mechanism of anticonvulsant action. Methods Anticonvulsant and toxic ...Aim To investigate the synergistic effect of the combination of pinellia total alkaloid （PTA） and uncaria total alkaloid （UTA）, and explore the mechanism of anticonvulsant action. Methods Anticonvulsant and toxic effect profiles of combinations of PTA with UTA, alone and at three fixed ratios of 1：4, 1 ：1, 4：1, were evaluated in maximal electroshock （MES）-induced seizures and acute toxicity test in mice. Respective ED50 and LD50 were calculated with Bliss＇s method. Their synergistic effect were evaluated by isobolographic analysis and allowed the determination of benefit indices （BI） for respective combinations. The model of convulsive rats kindled by penicillin topically injected into cortex was used to investigated the content of Glu, Asp, Gly and GABA in hippocampus using high performance liquid chromatography （HPLC）. Results Combinations of PTA and UTA at the ratio of 4：1 were synergistic in MES test and antagonistic in acute toxicity test, showing the best profile for combinations of PTA with UTA. In contrast, the ratios of 1 ：4 and 1 ： 1, despite synergistic in MES test, were additive in acute toxicity test. The 4：1 combination and two drugs alone significantly decreased Glu level and increased GABA level in the hippocampus, but the GABA level in the 4：1 combination group was higher than that in the two drugs alone groups. They did not have significant influence on the levels of ASp and Gly. Conclusion Combinations of PTA and UTA at 4：1 ratio demonstrated synergistic effect in anticonvulsant action and antagonistic effect in toxicity. The anticonvulsant mechanism might be related to decreasing the excitability of Glutamatergic neurons and increasing the inhibition of GABAergic neurons.展开更多
基金a phase study of a key project of the Fourteenth Five-Year Plan of the Institute for the History of Natural Sciences,Chinese Academy of Sciences:“A Comparative Study of the Sino-Foreign History of Scientific and Technological Innovation:The Road to Scientific and Technological Self-Reliance and Self-Improvement”,E2291J01。
文摘The transfer of pressurized water reactor(PWR)technology from France to China is an important event in the history of Sino-French scientific and technological relations.China has gradually achieved self-reliance in the field of PWR technology through the introduction and subsequent absorption of France's 900 MW reactors.Compared with the process of introducing and absorbing similar technology from the United States by France,China's experience has been more complicated.This circumstance reflects the differences in the nuclear power technology systems between the two countries.France's industrial strength and early acquisition of nuclear power technology laid a solid foundation for mastering PWR technology.On the other hand,although China established a weak foundation through the implementation of the"728 Project,"and tried hard to negotiate with France,the substantive content of the technology transfer was very limited.By way of the policy transition from"unhooking of technology and trade"to"integration of technology and trade,"China ultimately accomplished the absorption and innovation of PWR technology through the Ling'ao NPP.
文摘Loess soils are widely distributed worldwide and typical in northwest China,and excessive agricultural irrigation has caused landslides in the area,specifi cally in the Heifangtai loess region in Lanzhou,Gansu,China.Geophysical exploration is an essential method in landslide engineering geological surveys,and geological surveying,drilling,geophysical prospecting,monitoring,and other methods are used for performing engineering geological evaluation and obtaining comprehensive basic data for landslide protection design and construction.The theoretical feasibility of using geophysical methods in loess landslide detection is essential.On the basis of the shallow geological structure of the Heifangtai landslide region in Lanzhou,Gansu,China,a typical geoelectric model of the magnetotelluric method was established,and the loess landslide area was modeled through a two-dimensional fi nite element method,forward numerical simulation,and engineering geological analysis.The distribution characteristics of the magnetotelluric field were determined.This is a typical application of the geological process analysis method in geophysical exploration.This study provides the typical stratigraphic structure and electrical characteristics of different groundwater distributions in Heifangtai,Gansu,China,verifi es the accuracy of forward modeling and calculation results,and provides a detailed theoretical basis for landslide detection through magnetotelluric methods.Through the numerical simulation of the forward modeling of the Heifangtai landslide region in Lanzhou,Gansu,China,this study can provide a detailed geophysical basis for landslide investigation,corroborate results of geological investigation and landslide design,and facilitate the sustainable development of agriculture in Heifangtai.
基金supported by the Construction S&T Project of Department of Transportation of Sichuan Province(Grant No.2023A02,No.2024A04,No.2020A01)the Sichuan Science and Technology Program(Grant No.2022YFG0141)+3 种基金the Research Project of Sichuan Highway Planning,Survey,Design,and Research Institute Ltd.(Grant No.KYXM2021000049,No.KYXM2022000038,No.KYXM2023000056)the National Natural Science Foundation of China(41630640)the National Science Foundation of Innovation Research Group(41521002)the National Natural Science Foundation of China(41790445).
文摘A wide range of terrain features and landforms,which are exemplified by intricate geological formations and diverse rock compositions,are found in the western mountainous regions of China.These areas frequently encounter geological disasters.As one of the natural disasters,landslides lead to considerable loss of human life and property.Considering mitigation of the losses caused by landslide disasters,a necessary measure for disaster prevention and mitigation involves conducting detailed investigations and monitoring of landslides,which is also the cornerstone of landslide warning.This study compares and analyzes the feasibility of the magnetotelluric detection method for landslides using the results of engineering geological surveys and landslide monitoring.The study aims to address the scientific problem of the validity of using magnetotelluric methods to detect landslide development processes.The Tangjiawan landslide signal on the left side of the K94+000~K94+145 section of the Wenma Expressway is analyzed by employing engineering geological survey,magnetotelluric detection,landslide monitoring,landslide analysis,and other methods.Analysis results provide the static electrical characteristics of lithology,structure,and groundwater,as well as the dynamic electrical characteristics of landslide development.This study focuses on analyzing the relationship between the methods of magnetotelluric detection and engineering geological surveys and the results of landslide monitoring.The workflow and methods for data collection,processing,inversion,interpretation,and analysis using the magnetotelluric method to detect the dynamic development process of landslides are presented in the conclusion.Preliminary conclusions indicate a strong correlation between the dynamic changes in magnetotelluric wave impedance with the surface displacement of landslides and the dynamic changes in groundwater.The use of the magnetotelluric method for landslide detection and monitoring is a feasible example.The research results can offer certain technical references for the detection and monitoring of landslides using magnetotelluric methods and also provide references and guidance for the selection of diversified landslide monitoring methods in the future.
基金This study was jointly supported by the following funds awarded to Professor Danling TANG:Guangdong Natural Science Foundation(05102008 and 04001306),ChinaKey Innovation Project of Chinese Academy of Sciences(CAS)(KZCX3-SW-227-3)+3 种基金"0ne Hundred Talents Program"of CAS(Ybrjh0403)Authors are grateful to projects of South China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences(2007TS10 and 2007ZD03)High-tech Research and Development Program of China(2006AA100303)Chinese Ecosystem Research Network(http://www.cerndata.ac.cn),Dr.Guifeng WEI of Jinan University and the Key Innovation Project of CAS(KZCX3-SW-214).
文摘Economic development around the Daya Bay, China has profoundly affected the marine environment in the bay area in recent years, particularly since the operation of Daya Bay Nuclear Power Station （DNPS） in 1994. This study analyzed the changes of water temperature and harmful algal blooms （HABs） for two periods： 1983-1993 and 1994-2004, using in situ and satellite data. Results showed that yearly mean surface water temperature （SWT） and Chl-a concentration （Chl-a） increased by 1.1 ℃ and 1.9 mg/m^3, respectively, after 1994. The monthly occurrence of HAB was found to have increased also. HABs appeared only in spring and autumn before 1994, but occurred all the year round after 1994. SWT, Chl-a and HABs all increased significantly in May. Those changes were associated with environmental changes in this area, such as thermal discharge from the DNPS and enhancement of eutrophication from human activities around the Daya Bay.
基金sponsored by National Natural Science Foundation of China (Grant Nos. 40774029, 40674037, and 40374024)the National Hi-tech Research and Development Program of China (863 Program) (No. 2007AA09Z310)the Program for New Century Excellent Talents in University (NCET).
文摘Based on the analysis of the conjugate gradient algorithm, we implement a threedimensional （3D） conjugate gradient inversion algorithm with magnetotelluric impedance data. During the inversion process, the 3D conjugate gradient inversion algorithm doesn＇ t need to compute and store the Jacobian matrix but directly updates the model from the computation of the Jacobian matrix. Requiring only one forward and four pseudo-forward modeling applications per frequency to produce the model update at each iteration, this algorithm efficiently reduces the computation of the inversion. From a trial inversion with synthetic magnetotelluric data, the validity and stability of the 3D conjugate gradient inversion algorithm is verified.
文摘Novel schemes for a charge sensitive amplifier （CSA） and a CR-（RC）, semi-Gaussian shaper in a fully integrated CMOS readout circuit for particle detectors are presented. The CSA is designed with poly-resistors as feedback components to reduce noise. Compared with conventional CSA, the input referred equivalent noise charge（ENC） is simulated to be reduced from 5036e to 2381e with a large detector capacitance of 150pF at the cost of 0.5V output swing loss. The CR-（RC）,semi-Gaussian shaper uses MOS transistors in the triode region in series with poly-resistors to compensate process variation without much linearity reduction.
基金supported by the National Natural Science Foundation of China(No.41104068)the Deep Exploration in China,Sino Probe-03-05
文摘Scalar CSAMT is only suitable for measurements in one and two dimensions perpendicular to geological structures. For complex 3D geoelectric structure, tensor CSAMT is more suitable. In this paper, we discuss 3D tensor CSAMT forward modeling using the vector finite-element method. To verify the feasibility of the algorithm, we calculate the electric field, magnetic field, and tensor impedance of the 3D CSAMT far-zone field in layered media and compare them with theoretical solutions. In addition, a three-dimensional anomaly in half-space is also simulated, and the response characteristics of the impedance tensor and the apparent resistivity and impedance phase are analyzed. The results suggest that the vector finite-element method produces high-precision electromagnetic field and impedance tensor data, satisfies the electric field discontinuity, and does not require divergence correction using the vector finite-element method.
文摘A monolithic integrated CMOS preamplifier is presented for neural recording applications. Two AC-coupied capacitors are used to eliminate the large and random DC offsets existing in the electrode-electrolyte interface. Diode-connected nMOS transistors with a negative voltage between the gate and source are candidates for the large resistors necessary for the preamplifier. A novel analysis is given to determine the noise power spectral density. Simulation results show that the two-stage CMOS preamplifier in a closed-loop capacitive feedback configuration provides an AC in-band gain of 38.8dB,a DC gain of 0,and an input-referred noise of 277nVmax, integrated from 0. 1Hz to 1kHz. The preamplifier can eliminate the DC offset voltage and has low input-referred noise by novel circuit configuration and theoretical analysis.
基金sponsored by National Natural Science Foundation of China(Grant No.40774029,40374024)the National Hi-tech Rsearch and Development Program of China(863 Program)(No.2007AA09Z310,)the Program for New Century Excellent Talents in University(NCET)
文摘We implement a parallel algorithm with the advantage of MPI （Message Passing Interface） to speed up the rapid relaxation inversion for 3D magnetotelluric data. We test the parallel rapid relaxation algorithm with synthetic and real data. The execution efficiency of the algorithm for several different situations is also compared. The results indicate that the parallel rapid relaxation algorithm for 3D magnetotelluric inversion is effective. This parallel algorithm implemented on a common PC promotes the practical application of 3D magnetotelluric inversion and can be suitable for the other geophysical 3D modeling and inversion.
基金Natural Science Foundation of Shanxi Province(No 20041109).
文摘Aim To investigate the synergistic effect of the combination of pinellia total alkaloid （PTA） and uncaria total alkaloid （UTA）, and explore the mechanism of anticonvulsant action. Methods Anticonvulsant and toxic effect profiles of combinations of PTA with UTA, alone and at three fixed ratios of 1：4, 1 ：1, 4：1, were evaluated in maximal electroshock （MES）-induced seizures and acute toxicity test in mice. Respective ED50 and LD50 were calculated with Bliss＇s method. Their synergistic effect were evaluated by isobolographic analysis and allowed the determination of benefit indices （BI） for respective combinations. The model of convulsive rats kindled by penicillin topically injected into cortex was used to investigated the content of Glu, Asp, Gly and GABA in hippocampus using high performance liquid chromatography （HPLC）. Results Combinations of PTA and UTA at the ratio of 4：1 were synergistic in MES test and antagonistic in acute toxicity test, showing the best profile for combinations of PTA with UTA. In contrast, the ratios of 1 ：4 and 1 ： 1, despite synergistic in MES test, were additive in acute toxicity test. The 4：1 combination and two drugs alone significantly decreased Glu level and increased GABA level in the hippocampus, but the GABA level in the 4：1 combination group was higher than that in the two drugs alone groups. They did not have significant influence on the levels of ASp and Gly. Conclusion Combinations of PTA and UTA at 4：1 ratio demonstrated synergistic effect in anticonvulsant action and antagonistic effect in toxicity. The anticonvulsant mechanism might be related to decreasing the excitability of Glutamatergic neurons and increasing the inhibition of GABAergic neurons.
