影响论文录用的几类常见“硬伤”及其防范对策——以《军械士官》为例

《军械士官》未录用的稿件中,普遍存在一些经适当编辑加工后依然不能消除的"硬伤"。为提高办刊质量,采用分析归纳法对这些"硬伤"进行了梳理总结,并从探讨防范文体不符、选题不当、题文脱节、摘要不规范等常见问题入手,提出了论文选题、确定题名、归纳摘要时的一般方法及相应对策。以编者视角,阐述了编者面对这些问题时的编辑加工技巧,期望使作者和编者达到共赢。

电视连续剧《精忠岳飞》“硬伤”举隅

电视连续剧《精忠岳飞》在国内播映后,受到广泛关注。该剧虽宣称以"用最切合史料记载的方式来讲述岳飞的生平及他带领岳家军保卫南宋河山的传奇故事""展现史上最真实的岳飞",但由于该剧过度市场化、娱乐化的缺陷,导致了诸多谬误,潜移默化中给观众灌输了错误的历史观念与史实。历史剧创作应依据历史资料,遵循历史精神,避免历史和常识性错误,恰当塑造历史人物,坚持历史真实与艺术真实的有机统一。

消除“硬伤”,打造高效课堂的几点体会

高效课堂是每一位教师追求的目标,本文从消除"硬伤"这个角度列举几类常见的"硬伤"并结合自身教学实践给出了解决方案.

“硬伤”和“瑕疵”

央视播出的历史电视剧《汉武大帝》引起了许多观众的关注，收视率不断攀升。但剧中也存在着一些遗憾和不足，有人称之为是影视剧的“硬伤”和“瑕疵”。

“兰亭奖”部分提名奖作品“硬伤”分析

备受关注的全国书法专业最高奖——首届中国书法兰亭奖早已尘埃落定，据有关报道称，此次共收到创作稿件二万三千四百八十六件。经评委会评选，

防范习作“硬伤”

在写作训练中,老师应该着意引导学生明确习作常见的"硬伤",从而使他们在日常训练中通过刻意去避免这些"硬伤"来提升自己的习作水准。

Relationship between subsurface damage and surface roughness of ground optical materials

A theoretical model of relationship between subsurface damage and surface roughness was established to realize rapid and non-destructive measurement of subsurface damage of ground optical materials.Postulated condition of the model was that subsurface damage depth and peak-to-valley surface roughness are equal to depth of radial and lateral cracks in brittle surface induced by small-radius(radius≤200 μm)spherical indenter,respectively.And contribution of elastic stress field to the radial cracks propagation was also considered in the loading cycle.Subsurface damage depth of ground BK7 glasses was measured by magnetorheological finishing spot technique to validate theoretical ratio of subsurface damage to surface roughness.The results show that the ratio is directly proportional to load of abrasive grains and hardness of optical materials,while inversely proportional to granularity of abrasive grains and fracture toughness of optical materials.Moreover,the influence of the load and fracture toughness on the ratio is more significant than the granularity and hardness,respectively.The measured ratios of 80 grit and 120 grit fixed abrasive grinding of BK7 glasses are 5.8 and 5.4,respectively.

Cellular immune function and liver damage in post hepatitic cirrhosis

AIM To study the cellular immune function in patients with post hepatitic cirrhosis (PHC) and its relation with different liver damages.

Up-regulation of NAD(P)H quinone oxidoreductase 1 during human liver injury

AIM： To investigate the expression and activity of NAD（P）H quinone oxidoreductase 1 （NQO1） in human liver specimens obtained from patients with liver damage due to acetaminophen （APAP） overdose or primary biliary cirrhosis （PBC）. METHODS： NQOt activity was determined in cytosol from normal, APAP and PBC liver specimens. Western blot and immunohistochemical staining were used to determine patterns of NQO1 expression using a specific antibody against NQO1. RESULTS： NQO1 protein was very low in normal human livers. In both APAP and PBC livers, there was strong induction of NQO1 protein levels on Western blot. Correspondingly, significant up-regulation of enzyme activity （16- and 22-fold, P〈0.05） was also observed in APAP and PBC livers, respectively. Immunohistochemical analysis highlighted injury-specific patterns of NQO1 staining in both APAP and PBC livers. CONCLUSION： These data demonstrate that NQO1 protein and activity are markedly induced in human livers during both APAP overdose and PBC. Up-regulation of this cytoprotective enzyme may represent an adaptive stress response to limit further disease progression by detoxifying reactive species.

Pre-existing cirrhosis is associated with increased mortality of traumatic patients: Analysis of cases from a trauma center in East China

AIM:To determine the impact of cirrhosis on trauma patients and define the factors predicting death.METHODS:The data on patients admitted to the trauma center from January 2000-2005 were studied retrospectively.The clinical variables were recorded and compared to identify the factors differentiating cirrhotic trauma survivors from non survivors.Child's classification criteria were derived from the reviewed charts of cirrhotic trauma patients to evaluate their predictive value in cirrhotic trauma.Trauma registry was also used to generate a trauma control group by matching for age,sex,abbreviated injury score(AIS)over the same period of time.The outcome variables compared were mortality rate,time of ICU and hospital stay.Results were expressed as mean ± SD.These data were analyzed by SPSS.11.0 statistical software.Univariate analysis was performed to identify significant medical factors for survivor and non survivors subjected to chi-square test.Fisher's exact test and Student's t test were performed to determine the statistical difference between cirrhotic and control groups.P < 0.05 was considered statistically significant.RESULTS:Poor prognosis of traum patients was associated with one or more of the following findings:ascitcs,hyperbilirubinemia(more than 2 mg/dL),hypoalbuminemia(less than 3.5 mg/dL),and prolonged prothrombin time(more than 12.5 seconds).Although Child's classification was used to predict the outcome in cirrhotic patients undergoing portacaval shunt procedures,no significant difference was found in mortality rate as a function of Child's classification.CONCLUSION:Cirrhosis is associated with a highermortality,a longer time of ICU and hospital stay of trauma patients.It seems that treatment of trauma patients with pre-existing severe liver disease is a challenge to surgeons.

Oxidative damage,pro-inflammatory cytokines,TGF-αand c-myc in chronic HCV-related hepatitis and cirrhosis

AIM： To assess whether a correlation exists between oxidative DNA damage occurring in chronic HCV-related hepatitis and expression levels of pro-inflammatory cytokines, TGF-α and c-myc. METHODS： The series included 37 patients with chronic active HCV-related hepatitis and 11 with HCV-related compensated cirrhosis. Eight-hydroxydeoxyguanosine in liver biopsies was quantified using an electrochemical detector. The mRNA expression of TNF-α, IL-1β, TGF-α and c-myc in liver specimens was detected by semiquantitative comparaUve RT-PCR. RESULTS： TNF-α levels were significantly higher in hepatitis patients than in cirrhosis patients （P=0.05）. IL-1β was higher in cirrhosis patients （P=0.05）. A sig- nificant correlation was found between TNF-α and staging （P= 0.05） and between IL-1β levels and grading （P=0.04）. c-myc showed a significantly higher expression in cirrhosis patients （P=0.001）. Eight-hydroxydeoxyguanosine levels were significantly higher in cirrhosis patients （P=0.05） and in HCV genotype 1 （P=0.03）. Considering all patients, 8-hydroxydeoxyguanosine levels were found to be correlated with genotype （P=0.04） and grading （P=0.007）. Also multiple logistic regression analysis demonstrated a significant correlation among the number of DNA adducts, TNF-α expression and HCV genotype （P= 0.02）. CONCLUSION： In chronic HCV-related liver damage, oxidative DNA damage correlates with HCV genotype, grading and TNF-α levels. As HCV-related liver damage progresses, TNF-α levels drop while IL-1β and c-myc levels increase, which may be relevant to liver carcinogenesis.

Neurogenic bowel dysfunction in patients with spinal cord injury, myelomeningocele, multiple sclerosis and Parkinson’s disease

Exciting new features have been described concerning neurogenic bowel dysfunction,including interactions between the central nervous system,the enteric nervous system,axonal injury,neuronal loss,neurotransmission of noxious and non-noxious stimuli,and the fields of gastroenterology and neurology.Patients with spinal cord injury,myelomeningocele,multiple sclerosis and Parkinson's disease present with serious upper and lower bowel dysfunctions characterized by constipation,incontinence,gastrointestinal motor dysfunction and altered visceral sensitivity.Spinal cord injury is associated with severe autonomic dysfunction,and bowel dysfunction is a major physical and psychological burden for these patients.An adult myelomeningocele patient commonly has multiple problems reflecting the multisystemic nature of the disease.Multiple sclerosis is a neurodegenerative disorder in which axonal injury,neuronal loss,and atrophy of the central nervous system can lead to permanent neurological damage and clinical disability.Parkinson's disease is a multisystem disorder involving dopaminergic,noradrenergic,serotoninergic and cholinergic systems,characterizedby motor and non-motor symptoms.Parkinson's disease affects several neuronal structures outside the substantia nigra,among which is the enteric nervous system.Recent reports have shown that the lesions in the enteric nervous system occur in very early stages of the disease,even before the involvement of the central nervous system.This has led to the postulation that the enteric nervous system could be critical in the pathophysiology of Parkinson's disease,as it could represent the point of entry for a putative environmental factor to initiate the pathological process.This review covers the data related to the etiology,epidemiology,clinical expression,pathophysiology,genetic aspects,gastrointestinal motor dysfunction,visceral sensitivity,management,prevention and prognosis of neurogenic bowel dysfunction patients with these neurological diseases.Embryological,morphological and experimental studies on animal models and humans are also taken into account.

A nonlinear rheological damage model of hard rock

By adopting cyclic increment loading and unloading method, time-independent and time-dependent strains can be separated. It is more reasonable to describe the reversible and the irreversible deformations of sample separately during creep process. A nonlinear elastic-visco-plastic rheological model is presented to characterize the time-based deformational behavior of hard rock. Specifically, a spring element is used to describe reversible instantaneous elastic deformation. A reversible nonlinear visco-elastic （RNVE） model is developed to characterize recoverable visco-elastic response. A combined model, which contains a fractional derivative dashpot in series with another Hook’s body, and a St. Venant body in parallel with them, is proposed to describe irreversible visco-plastic deformation. Furthermore, a three-stage damage equation based on strain energy is developed in the visco-plastic portion and then nonlinear elastic-visco-plastic rheological damage model is established to explain the trimodal creep response of hard rock. Finally, the proposed model is validated by a laboratory triaxial rheological experiment. Comparing with theoretical and experimental results, this rheological damage model characterizes well the reversible and irreversible deformations of the sample, especially the tertiary creep behavior.

Sclerosing cholangitis following severe trauma: Description of a remarkable disease entity with emphasis on possible pathophysiologic mechanisms

MM： Persistent cholestasis is a rare complication of severe trauma or infections. Little is known about the possible pathomechanisms and the clinical course.METHODS： Secondary sclerosing cholangitis was diagnosed in five patients with persistent jaundice after severe trauma （one burn injury, three accidents, one power current injury）. Medical charts were retrospectively reviewed with regard to possible trigger mechanisms for cholestasis, and the clinical course was recorded.RESULTS： Diagnosis of secondary sclerosing cholangitis was based in all patients on the primary sclerosing cholangitis （PSC）-Iike destruction of the intrahepatic bile ducts at cholangiography after exclusion of PSC. In four patients, arterial hypotension with subsequent ischemia may have caused the bile duct damage, whereas in the case of power current injury direct thermal damage was assumed to be the trigger mechanism. The course of secondary liver fibrosis was rapidly progressive and proceeded to liver cirrhosis in all four patients with a follow-up 〉2 years. Therapeutic possibilities were limited.CONCLUSION： Posttraumatic sderosing cholangitis is a rare but rapidly progressive disease, probably caused by ischemia of the intrahepatic bile ducts via the peribiliary capillary plexus due to arterial hypotension.Gastroenterologists should be aware of this disease in patients with persistent cholestasis after severe trauma.

Chitosan that Dissolves in Hard Water Represses Mutagenicity

Chitosan is derived by deacetylation of chitin, a major component of the shells of crustacea such as crabs and shrimps. In this experiment using the Ames test, there was antimutagenic effect by the water-soluble chitosan that dissolved in hard water （CHW）. The Ames test was performed using Salmonella typhimurium TA98 and TA100. For the antimutagenic test, and the desmutagenic and bioantimutagenic tests, Trp-P-2, 2AA and AF-2 were used as mutagens. Tests for spontaneous mutation rate without mutagens were performed using S. typhimurium TA98 and TA100. When several concentrations of CHW were directly added to Minimal Glucose Plates, there were no changes in the number of His＋ revertants of TA98 and TA100. In desmutagenic and bioantimutagenic tests, the number of His^＋ revertants of TA98 and TA100 decreased. In the test for spontaneous mutation rate, the number of His＋ revertants of TA98 and TA 100 decreased slightly. When a concentration of CHW was added to examine antimutagenic effects, there was no change in the viable cell count of TA98 and TA100. From these results, AF-2 that is a direct mutagen may combine with CHW, and that may also be carrying out the inactivation. CHW possibly acts directly on the DNA by decreasing the rate at which mutation is caused to the strain＇s promutagens, Trp-P-2 and 2AA. This is evident from the decreased spontaneous mutation rate without a decreased viable cell count.

Withdrawing method of the stiffening tube incidentally inserted into the descending colon

We experienced a very rare complication of colonoscopy,a migration of stiffening tube into the colorectum. We herein introduce a withdrawing method of migrating stiffening tube incidentally inserted into the colorectum.A 65-year-old Japanese woman underwent colonoscopy because of abdominal discomfort. We used stiffening tube to insert the scope to the proximal colon because of her redundant sigmoid colon. When withdrawing the scope,we realized that the tube was fully inside the colorectum.We could not remove the tube instantly, and it reached the splenic flexure, finally. We reinserted the scope through the migrating tube, straightened the scope, and withdrew it holding a slight angle of the scope over the proximal end of the tube. Then, we could safely remove the tube along with the scope through the anus.

Coupled effects of stress damage and drilling fluid on strength of hard brittle shale

During well drilling process,original stress state of hard brittle shale will be changed due to stress redistribution and concentration,which leads to stress damage phenomenon around the borehole.Consequently,drilling fluid will invade into formation along the tiny cracks induced by stress damage,and then weaken the strength of hard brittle shale.Based on this problem,a theoretical model was set up to discuss damage level of shale under uniaxial compression tests using acoustic velocity data.And specifically,considering the coupled effect of stress damage and drilling fluid,the relationship between hard brittle shale strength and elapsed time was analyzed.

Office Furniture Design for Wheelchair User

There are an estimated 1.19 million wheelchair users in Spain. People use wheelchairs for a variety of reasons, the most common one is paralysis from spinal cord injuries. Current estimates indicate there are around 504,000 people alive in Spain with spinal cord injuries. Among other reasons for using wheelchairs are： fatigue from multiple sclerosis, muscle weakness from muscular dystrophy, lower limb spasticity from cerebral palsy, and missing limbs due to amputation. People who use wheelchairs may encounter a variety of obstacles at their workstations depending on their limitations. Some possible accommodations could be adjustable height desk or table for a person who cannot work comfortably at an existing desk, accessible filing system or office supplies, and frequently used materials on most accessible shelves or drawers for a person who cannot reach upper and lower shelves and drawers. This paper presents the graphical design of a workstation for wheelchair users, in this case, technical, anthropometric, ergonomic, aesthetics and scientists aspects have been analyzed. The design of composite structure conduct to explicit safety constraints applied to office furniture requirements kept continuously current and updated as part of innovation. Finally, results are showed in a three-dimensional model.

《大学语文》上册校订

普通高等学校少数民族预科教材《大学语文》存在诸多技术性失误和部分知识性失误。据初步统计,仅上册的"硬伤"即有77条(169处)。本文逐条加以校订,以期为预科师生提供教学方便,也为教材编委提供修订参考。

Traumatic subdural hydroma developing into chronic subdural hematoma

Objective: To probe the incidence, pathogenesis and clinical characteristics of traumatic subdural hydroma (TSH) developing into chronic subdural hematoma (CSDH). Methods: We retrospectively analyzed the clinical data of 32 patients with TSH developing into CSDH and reviewed related literature. Results: 16.7% of TSH developed into CSDH in this study. The time of evolution was from 22 to 100 days after head injury. All the patients were cured with hematoma drainage. Conclusions: TSH is one of the origins of CSDH. The clinical characteristics of TSH developing into CSDH follow that the ages of the patients are polarized, that the evolution often happens in the patients with small chronic hydromas and being treated conservatively, that the patients are usually injured deceleratedly and that the accompanying cerebral damage is often very mild.