Objective: To explore the possible mechanisms of "JIN San Zhen" (JIN’s 3 acupoints groups) in treatment of mental retardation. Methods: A total of 38 female mice were randomly divided into normal control (n...Objective: To explore the possible mechanisms of "JIN San Zhen" (JIN’s 3 acupoints groups) in treatment of mental retardation. Methods: A total of 38 female mice were randomly divided into normal control (n=10), sham operation (n=10), model (n=8) and acupuncture (n=10) groups. "Si Shen Zhen" [4 points around "Baihui" (GV 20): 0.3 cm anterior, posterior, left and right to GV 20 respectively], and "Zhi San Zhen" ["Shenting" (GV 24) and bilateral "Benshen" (GB 13)] of "JIN San Zhen" series are used. The memory ability, AChE positive fiber density and mono amines transmitters of the brain are used as the indexes. Results: After 8 days’ treatment, cerebral ischemia induced mental retardation (decline of learning memory ability) was improved significantly shown by Y maze test (P<0.05-0.01), simultaneously, AChE positive fiber density of the frontal cerebral cortex and hippocampus, serotonie (5 HT), noradrenaline (NA) and dopamine (DA) contents of the brain increased significantly (P<0.05). Conclusion: Acupuncture induced increase of AChE, 5 HT, NA and DA in the brain may contribute to the effect of acupuncture in improving the memory capability of the RD mice.展开更多
Objective To observe the clinical effects on upper extremities function recovery of cerebral apoplexy induced hemiplegia by combination of JIN＇s 3-needle technique and motor function trai- ning. Methods Eight-seven c...Objective To observe the clinical effects on upper extremities function recovery of cerebral apoplexy induced hemiplegia by combination of JIN＇s 3-needle technique and motor function trai- ning. Methods Eight-seven cases of cerebral apoplexy induced hemiplegia were randomized into an observation group （44 cases） and a control group （43 cases）. JIN＇s 3-needle technique and motor function training were both adopted for the observation group. Three temporal acupuncture points on the affected side were selected. Three lower arm points, namely Qfichi （曲池 LI 11 ）, Waiguan （外关 TE 5） and Hegu （ 合谷 LI 4） were adopted for flaccid hemiplegia. While 3 upper arm points for relieving spasm, namely Jiquan （极泉HT 1）, Chize （尺泽 LU 5） and Neiguan （内关 PC 6） were chosen for spastic hemiplegia. Motor function training was applied alone for the control group. Treating courses for both groups were 5 weeks. And scores of Brunnstrom and FugI-Meyer assessments of the affected limbs were analyzed. Results Improvement on scores of FugI-Meyer and Brunnstrom assessments were observed for both groups after the treatment（P〈0. 05, P〈0. 01 ）. The post-treatment scores of the observation group was better than that of the control group after the treatment （ P〈0.05, P〈0.01 ）. Conclusion Treat- ment of combination of JIN＇s 3-needle technique with motor function training can obviously improve the motor function of the upper extremities of patients with cerebral apoplexy induced hemiplegia.展开更多
Objective： To observe the influence of acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） on cerebral vasomotoricity of ischemic stroke and its possible mechanism. Methods： All the appropriate cases were rando...Objective： To observe the influence of acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） on cerebral vasomotoricity of ischemic stroke and its possible mechanism. Methods： All the appropriate cases were randomly divided into treatment and control groups with 80 cases in each group. The routine treatment of cerebral apoplexy was given to the two groups. Zusanli （ST 36） and Xuanzhong （GB 39） were added to the treatment group. The change of velocity of blood blow of the cerebral central artery was observed by transfrontal Doppler ultrasound detecting method before and after treatment to evaluate the cerebral basomotoricity of the patients. Results： The cerebral vasomotoricity in the treatment group was greatly improved compared with pre-treatment （P〈0.05） and there was a significant difference compared with the control group （P〈0.05）. Conclusion： Acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） could obviously improve the cerebral vosomotoricity of the patients with cerebral ischemic stroke, which might be one of the action mechanisms of acupuncture treatment for cerebral ischemic stroke.展开更多
Objective： To investigate the effects of acupuncture therapy on acute cerebral infarction. Methods： Eighty patients with acute cerebral infarction were randomly divided into a treatment group of 40 cases and a contr...Objective： To investigate the effects of acupuncture therapy on acute cerebral infarction. Methods： Eighty patients with acute cerebral infarction were randomly divided into a treatment group of 40 cases and a control group of 40 cases. Xuanzhong（GB 39）-throughSanyinjiao（SP 6） acupuncture was performed as a main treatment. The curative effects were compared between the two groups and the sizes of cerebral infarct, between pretreatment and posttreatment after one course of treatment. Results. The total recovery rate was 88.5% in the treatment group and 57.5% in the control group after one course of treatment. There was a significant difference between the two（P〈 0.05）. The rate of change in the infarct for the better was significantly higher in the treatment group than in the control group. There was also a significant difference（P〈 0.05）, Conclusion： This treatment is an effective method for lowering the rate of apoplectic disability and raising the cure rate,展开更多
文摘Objective: To explore the possible mechanisms of "JIN San Zhen" (JIN’s 3 acupoints groups) in treatment of mental retardation. Methods: A total of 38 female mice were randomly divided into normal control (n=10), sham operation (n=10), model (n=8) and acupuncture (n=10) groups. "Si Shen Zhen" [4 points around "Baihui" (GV 20): 0.3 cm anterior, posterior, left and right to GV 20 respectively], and "Zhi San Zhen" ["Shenting" (GV 24) and bilateral "Benshen" (GB 13)] of "JIN San Zhen" series are used. The memory ability, AChE positive fiber density and mono amines transmitters of the brain are used as the indexes. Results: After 8 days’ treatment, cerebral ischemia induced mental retardation (decline of learning memory ability) was improved significantly shown by Y maze test (P<0.05-0.01), simultaneously, AChE positive fiber density of the frontal cerebral cortex and hippocampus, serotonie (5 HT), noradrenaline (NA) and dopamine (DA) contents of the brain increased significantly (P<0.05). Conclusion: Acupuncture induced increase of AChE, 5 HT, NA and DA in the brain may contribute to the effect of acupuncture in improving the memory capability of the RD mice.
文摘Researches in recent years have shown that cellular immune factor plays an important role in the generation and development of cerebral hemorrhage1-3.
基金National Science and Technology Pillar Program in the Eleventh Five-Year Plan Period:2006BI12B02-3
文摘Objective To observe the clinical effects on upper extremities function recovery of cerebral apoplexy induced hemiplegia by combination of JIN＇s 3-needle technique and motor function trai- ning. Methods Eight-seven cases of cerebral apoplexy induced hemiplegia were randomized into an observation group （44 cases） and a control group （43 cases）. JIN＇s 3-needle technique and motor function training were both adopted for the observation group. Three temporal acupuncture points on the affected side were selected. Three lower arm points, namely Qfichi （曲池 LI 11 ）, Waiguan （外关 TE 5） and Hegu （ 合谷 LI 4） were adopted for flaccid hemiplegia. While 3 upper arm points for relieving spasm, namely Jiquan （极泉HT 1）, Chize （尺泽 LU 5） and Neiguan （内关 PC 6） were chosen for spastic hemiplegia. Motor function training was applied alone for the control group. Treating courses for both groups were 5 weeks. And scores of Brunnstrom and FugI-Meyer assessments of the affected limbs were analyzed. Results Improvement on scores of FugI-Meyer and Brunnstrom assessments were observed for both groups after the treatment（P〈0. 05, P〈0. 01 ）. The post-treatment scores of the observation group was better than that of the control group after the treatment （ P〈0.05, P〈0.01 ）. Conclusion Treat- ment of combination of JIN＇s 3-needle technique with motor function training can obviously improve the motor function of the upper extremities of patients with cerebral apoplexy induced hemiplegia.
文摘Objective： To observe the influence of acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） on cerebral vasomotoricity of ischemic stroke and its possible mechanism. Methods： All the appropriate cases were randomly divided into treatment and control groups with 80 cases in each group. The routine treatment of cerebral apoplexy was given to the two groups. Zusanli （ST 36） and Xuanzhong （GB 39） were added to the treatment group. The change of velocity of blood blow of the cerebral central artery was observed by transfrontal Doppler ultrasound detecting method before and after treatment to evaluate the cerebral basomotoricity of the patients. Results： The cerebral vasomotoricity in the treatment group was greatly improved compared with pre-treatment （P〈0.05） and there was a significant difference compared with the control group （P〈0.05）. Conclusion： Acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） could obviously improve the cerebral vosomotoricity of the patients with cerebral ischemic stroke, which might be one of the action mechanisms of acupuncture treatment for cerebral ischemic stroke.
文摘Objective： To investigate the effects of acupuncture therapy on acute cerebral infarction. Methods： Eighty patients with acute cerebral infarction were randomly divided into a treatment group of 40 cases and a control group of 40 cases. Xuanzhong（GB 39）-throughSanyinjiao（SP 6） acupuncture was performed as a main treatment. The curative effects were compared between the two groups and the sizes of cerebral infarct, between pretreatment and posttreatment after one course of treatment. Results. The total recovery rate was 88.5% in the treatment group and 57.5% in the control group after one course of treatment. There was a significant difference between the two（P〈 0.05）. The rate of change in the infarct for the better was significantly higher in the treatment group than in the control group. There was also a significant difference（P〈 0.05）, Conclusion： This treatment is an effective method for lowering the rate of apoplectic disability and raising the cure rate,
