码头工程钻孔灌注桩施工产生的悬浮泥沙影响研究

本文建立了舟山金塘港区宏运物流有限公司通用码头附近海域二维水动力模型和悬浮物扩散预测模型,对潮流进行数值模拟,模拟结果可反映工程附近海域的潮流动力情况。进一步计算了概化桩基产生的悬浮泥沙源强,采取连续性移动点源模拟了码头桩基施工过程中产生的悬浮泥沙扩散,明确了悬浮泥沙扩散的范围和浓度,使得对钻孔灌注桩施工时产生的悬浮泥沙从定性描述细化到定量分析,有助于对周边敏感目标的影响分析和对海洋生物资源损失的定量计算。

Study on Near Field Dispersal of Fuel Air Explosive

Aim To study fuel dispersion in fuel air explosive(FAE) and computational ways of fuel dispersion velocity in the near area. Methods\ The dispersion process of fuel in FAE was analyzed by the use of results measured with KODAK EKTAPRO EM Motion Analyzer and setting up mechanical models. Results\ Computational methods for fuel dispersion velocity in the acceleration stage is given and taken as a base for the study of fuel dispersion in the intermediate and the far area. Conclusion\ When the fuel flow velocity is higher than that of the explosion gas in the center cavity, the fuel divides with the explosion gas and its velocity of flow reaches a maximum. The acceleration stage ends at that time. The fuel dispersion velocity at this time is the initial conditions for numeral analyses of dispersion process in the intermediate and far areas.

Fertilizer Overuse in China:Empirical Evidence from Farmers in Four Provinces

[Objective] This paper aims to empirically analyze the situation of fertilizer overuse in China, considering that fertilizer, important for China＇s crop production, has brought serious environmental pollution to China due to over application. [Method] Based on field survey data in four provinces of China, the magnitude of fertilizer overuse at farm level was empirically analyzed with Cobb-Douglas Produc- tion Function Method and profit optimization theory in the research. [Result] The resuits show that by average, 110.5 kg of chemical fertilizer were applied per mu of land, and 46.9 kg fertilizer was overused, occupying 42.5%. [Conclusion] There is large potential to reduce the overused amount and it is of great importance to re- duce fertilizer overuse effectively, which needs further intensive study.

Protective Effects of Tea Polyphenol on Cerebral Ischemia-Reperfusion Injury in Rats and Its Scavenging Oxy-radical and Anticerebral Lipid Peroxidation Effects

AIM To study the protective effects of tea polyphenol (TP) on cerebral ischemia reperfusion injury in rats and its scavenging oxygen free radical(OFR) activities and antilipid peroxidation in vitro . METHODS Cerebral ischemia reperfusion injury was produced by bilateral ligation of the common carotid arteries with vagus nerves and reperfusion for 45 min. The mitochondrial lipid peroxidation of rat brain induced by oxygen free radical was measured by thiobarbituric acid spectrophotometry. Superoxide anion (O 2) from xanthine xanthine oxidase system and hydroxyl radical (·OH) from Fe 2+ -H 2O 2 system were determined with spectrophotometry. RESULTS During Cerebral ischemia reperfusion,TP improved the activities of superoxide dismutase ( P 【0 05), GSH peroxidase( P 【0 01) and catalase( P 【0 01), while decreasing the maiondialdchyde content in the brain( P 【0 05) and brain water content ( P 【0 01). Tea polyphenol possessed significantly scavenging effects on ·OH produced by Fenton reaction and O 2 produced by xanthine xanthine oxidase system (the IC 50 were 2 2 mmol·L -1 and 1 9 mmol·L -1 respectively). Tea polyphenol could significant inhibit the lipid peroxidation of cerbral mitochondrial membrane induced by ·OH in a concentration dependent manner. CONCLUSION The results indicate that tea polyphenol could protect the injury on cerebral ischemia reperfusion in rats for OFR, these effects may be related to its scavenging effects on oxygen free radicals and antilipid peroxidant.

Study on the Soil Moisture Stress Level in Regulated Deficit Irrigation Experiment

On the basis of discussing the influencing mode of plant moisture stress on plant physiological process and the division of soil moisture availability range, the water suction values partitioning soil moisture were put forward, and then the corresponding water moistures under water stress were obtained by conversing together with characteristic curve of water moisture.

Application of Participatory Monitoring and Evaluation in Development of Animal Husbandry Technology

[Objective] This study aimed to provide references for the application of participatory monitoring and evaluation in the development of animal husbandry tech- nology. [Method] With the livelihood improvement program for agricultural and pas- toral area in northern Yunnan as the example, the development process of partici- patory animal husbandry was overviewed. And the monitoring and evaluation pro- cesses of participatory animal husbandry were introduced and analyzed. [Result] The monitoring and evaluation indicator system of participatory animal husbandry technol- ogy included 4 layers, namely technology, institutional system, personnel ability con- struction and effectiveness, and 11 third-level indicators, namely, technical characteristics, superiority-inferiority comparison, community and farmers, technical personnel, project personnel, economic indicators and social indicators. [Conclusion] This study provided the references for the application of participatory monitoring and evaluation in the development of animal husbandry technology.

A novel similarity measurement approach considering intrinsic user groups in collaborative filtering

To improve the similarity measurement between users, a similarity measurement approach incorporating clusters of intrinsic user groups（ SMCUG） is proposed considering the social information of users. The approach constructs the taxonomy trees for each categorical attribute of users. Based on the taxonomy trees, the distance between numerical and categorical attributes is computed in a unified framework via a proper weight. Then, using the proposed distance method, the nave k-means cluster method is modified to compute the intrinsic user groups. Finally, the user group information is incorporated to improve the performance of traditional similarity measurement. A series of experiments are performed on a real world dataset, M ovie Lens. Results demonstrate that the proposed approach considerably outperforms the traditional approaches in the prediction accuracy in collaborative filtering.

Monadically slicing programs with procedures

A two-phase monadic approach is presented for monadically slicing programs with procedures. In the monadic slice algorithm for interprocedural programs, phase 1 initializes the slice table of formal parameters in a procedure with the given labels, and then captures the callees＇ influence on callers when analyzing call statements. Phase 2 captures the callees＇ dependence on callers by replacing all given labels appearing in the corresponding sets of formal parameters. By the introduction of given labels, this slice method can obtain similar summary information in system-dependence-graph（SDG）-based algorithms for addressing the calling-context problem. With the use of the slice monad transformer, this monadic slicing approach achieves a high level of modularity and flexibility. It shows that the monadic interprocedural algorithm has less complexity and it is not less precise than SDG algorithms.

Colorectal mucosal histamine release by mucosa oxygenation in comparison with other established clinical tests in patients with gastrointestinally mediated allergy

AIM： This study evaluated colorectal mucosal histamine release in response to blinded food challenge-positive and-negative food antigens as a new diagnostic procedure. METHODS： 19 patients suffering from gastrointestinally mediated allergy confirmed by blinded oral provocation were investigated on grounds of their case history, skin prick tests, serum IgE detection and colorectal mucosal histamine release by ex vivo mucosa oxygenation. Intact tissue particles were incubated/stimulated in an oxygenated culture with different food antigens for 30 min. Specimens challenged with anti-human immunoglobulin E and without any stimulus served as positive and negative controls, respectively. Mucosal histamine release （% of total biopsy histamine content） was considered successful （positive）, when the rate of histamine release from biopsies in response to antigens reached more than twice that of the spontaneous release. Histamine measurement was performed by radioimmunoassay. RESULTS： The median （range） of spontaneous histamine release from colorectal mucosa was found to be 3.2 （0.1%-25.8%） of the total biopsy histamine content. Food antigens tolerated by oral provocation did not elicit mast cell degranulation 3.4 （0.4%-20.7%, P=0.4）, while anti-IgE and causative food allergens induced a significant histamine release of 5.4 （1.1%-25.6%, P = 0.04） and 8.1 （1.5%-57.9%, P = 0.008）, respectively. 12 of 19 patients （63.1%） showed positive colorectal mucosal histamine release in accordance with the blinded oral challenge responding to the same antigen （s）, while the specificity of the functional histamine release to accurately recognise tolerated foodstuffs was found to be 78.6%. In comparison with the outcome of blinded food challenge tests, sensitivity and specificity of history （30.8% and 57.1%）, skin tests （47.4% and 78.6%） or antigen-specific serum IgE determinations （57.9% and 50%） were found to be of lower diagnostic accuracy in gastrointestinally mediated allergy. CONCLUSION： Functional testing of the reactivity of colorectal mucosa upon antigenic stimulation in patients with gastrointestinally mediated allergy is of higher diagnostic efficacy.

Simplified Computation of Reflective Overpressure in Closed Cuboid Space Due to Internal Explosion

A simplified method is proposed for analyzing the overpressure history of an optional point on the walls of a closed cuboid due to its internal optional point-explosion. Firstly, the overpressure histories of all nodes on the walls of a cube with a side-length of 2 m are computed under a reference-charge explosion at each node of its inner space using the LS-DYNA software, and then are collected to form a reference database. Next, with the thought of the isoparametric finite element, an interpolating algori...

Changes of Protective Enzymes and Accumulation of Polyamines Induced by Boron Deficiency in Roots of Rape Seedlings

The effects of boron deficiency on the membrane permeability, the lipid peroxidation of membrane, the activities of the protective enzymes and the accumulation of polyamines in the roots of rape ( Brassica napus L. cv Zhongyou 821) plants were examined using solution culture experiment. Compared to the 20 mmol B m -3 treatment, boron deficient treatment (2 mmol B m -3 ) decreased root dry weight and increased the rate of solute leakage and malondialdehyde (MDA) concentration in the roots of rape. Similar patterns of change were observed in the level of lipid peroxidation (MDA concentration) and the rate of solute leakage under boron deficiency. Results suggested that a significant alteration of membrane composition had occurred under B deficiency. The concentration of putrescine and the ratio of putrescine to spermidine + spermine in the roots of rape increased significantly, and the activities of superoxide dismutase and catalase decreased in the roots of rape during B deficiency. But peroxidase activity in root of B deficient plant was higher than that of control plant.

Aerosol Filtration Application Using Fibrous Media—An Industrial Perspective

Filtration of aerosol particles using non-woven fibrous media is a common practice for air cleaning. It has found wide applications in industries and our daily lives. This paper overviews some of these applications and provides an industrial perspective. It starts from discussing aerosol filtration theory, followed by a brief review on the advancement of filtration media. After that, filtration applications in respiratory protection, dust collection, and engine in-take air cleaning are elaborated. These are the areas that the author sees as the typical needed ones in China's fast pace economical development endeavor, where air filtration enables the protection of human health, environment and equipment for sustainability.

Investigation on and industrial application of degrading of methanol feed in methanol to propylene process

At present, methanol to propylene(MTP) technology developed by Lurgi Company is adopted for commercial plants and refined methanol with the purity ≥99.85 wt% is required as the feed of MTP unit in Lurgi's technology.Therefore, high energy cost for refined methanol production is one of the bottlenecks to improve the economy of MTP technology. Reducing the grade of feed refined methanol may be an effective method to save energy and reduce operation costs in MTP process. In this work, experiments and process simulation were carried out to investigate the influence and feasibility of degrading the methanol feed. Experiments were conducted to investigate the influence of crude methanol feed on conversion and selectivity of MTP reaction as well as the performance of ZSM-5 catalyst. The experimental results showed that degrading the methanol feed had no obvious influence on the conversion and selectivity of MTP reactions and the catalyst deactivation was caused by the carbon accumulation and metals deposition on the active sites. The process simulation results showed that the influence on the conversion and selectivity as well as the stream load of MTP process was negligible if 98 mol% methanol was used as feed. Finally, industrial experiments were conducted by adjusting the operation parameters to degrade of feed methanol of the commercial 500 kt·a^(-1) MTP unit of Ningmei Group in China. The results of industrial application illustrated that annually 180 kt fuel coal and 150 kt desalted water as well as 1770 MW·h^(-1) electricity would be saved when the water content increased from 0.01% to 0.4%. This work has identified the feasibility to improve MTP technology by degrading the methanol feed.

ROUTE OPTIMIZING ALGORITHM OF AIRPORT SURFACE BASED ON GIS

The GIS technique is used for airport surface management to study the optimization of airplane taxiway for arrival and departure flights. The shortest paths are designed for just-arrived and ready-for-departing flights of the airport. Additionally, whether the flights could confront each other head-to-head on the taxiway is judged. In regard to the airport′s security and efficiency, airplanes must continuously taxi along the shortest route and the head-to-head confrontation should not occur. Two schemes are designed: One is to change the taxiing velocity of arrival flights, the other is to delay the starting time of departure flights. This algorithm is approved by a practical example.

Time-Ordered Collaborative Filtering for News Recommendation

Faced with hundreds of thousands of news articles in the news websites,it is difficult for users to find the news articles they are interested in.Therefore,various news recommender systems were built.In the news recommendation,these news articles read by a user is typically in the form of a time sequence.However,traditional news recommendation algorithms rarely consider the time sequence characteristic of user browsing behaviors.Therefore,the performance of traditional news recommendation algorithms is not good enough in predicting the next news article which a user will read.To solve this problem,this paper proposes a time-ordered collaborative filtering recommendation algorithm(TOCF),which takes the time sequence characteristic of user behaviors into account.Besides,a new method to compute the similarity among different users,named time-dependent similarity,is proposed.To demonstrate the efficiency of our solution,extensive experiments are conducted along with detailed performance analysis.

Mesalamine hypersensitivity and Kounis syndrome in a pediatric ulcerative colitis patient

5-aminosalicylic acid （mesalamine） rarely induces hyper- sensitivity reactions. If chest pain associated with atypical electrocardiographic changes are seen during its administration, one should always bear in mind type I variant of Kounis syndrome. This variant includes patients, of any age, with normal coronary arteries, without predisposing factors for coronary artery disease, in whom the acute release of inflammatory mediators from mast cells can induce either sudden coronary artery narrowing, without increase of cardiac enzymes and troponins, or coronary artery spasm that progresses to acute myocardial infarction, with elevated cardiac enzymes and troponins.

Prediction of Critical Endpoints Based on the PR Equation of State

In the design of chemical processes,such as catalytic cracking of bitumen and heavy oil,the knowledge of phase behavior at the critical endpoint is essential.Based on the PR equation of state,the algorithm developed by Heidemann and Khalil for calculating critical properties was used to compute critical points.An algorithm for determining the equilibrium phase of the critical point using the tangent plane criterion was developed,and was used to calculate the critical endpoints of different mixtures,including non-polar,polar and associating systems.The critical endpoint,representing the type of the phase behavior,was employed to fit the interaction parameter of mixtures in critical state at high pressure.Lines of critical endpoints for ternary mixtures were also determined with the algorithm.

Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line

AIM: To investigate synergism of inhibition of telomerase activity and proliferation of human colon cancer cells by combination of telomerase antisense oligonucleotides (ASODNs) simultaneously targeting human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) in vitro. METHODS: ASODN of hTR and ASODN of hTERT were transfected into human colon cancer SW480 cells by liposomal transfection reagents. Telomerase activity of SW480 cells was examined using telomeric repeat amplification protocol (TRAP)-enzyme-linked immunosorbent assay (PCR-ELISA). Proliferation activity of SW480 cells was tested by methyl thiazolyl tetrazolium assay. Apoptosis and cell cycle were analyzed by flow cytometry. RESULTS: The telomerase activity and cell survival rate in SW480 cells transfected with 0.2 μmol/L of ASODN of hTR or ASODN of hTERT for 24-72 h were significantly decreased in a time-dependent manner compared with those after treatment with sense oligonucleotides and untreated (telomerase activity: 24 h, 73%, 74% vs99%, 98%; 48 h, 61%, 55% vs98%, 99%; 72 h, 41%, 37% vs 99%, 97%; P<0.01; cell survival rate: 24 h, 88%, 86% vs594%, 98%; 48 h, 49%, 47% vs94%, 97%; 72 h, 44%, 42% vs92%, 96%; P<0.01). Moreover, the telomerase activity and the cell survival rate in SW480 cells treated by the combination of telomerase anti-hTR and anti-hTERT were more significantly suppressed than single anti-hTR or anti-hTERT (telomerase activity: 24 h, 59% vs 73%, 74%; 48 h, 43% vs61%, 55%; 72 h, 18% vs41%, 37%; P<0.01; cell survival rate: 24 h, 64% vs88%, 86%; 48 h, 37% vs49%, 47%; 72 h, 25% vs44%, 42%; P<0.01). Meanwhile, the apoptosis rates in the combination group were markedly increased compared with those in the single group (24 h, 18.0% vs7.2%, 7.4%; 48 h, 23.0% vs13.0%, 14.0%; 72 h, 28.6% vs 13.2%, 13.75; P<0.01). Cells in combination group were arrested at G0/G1 phase. CONCLUSION: Telomerase anti-hRT and anti-hTERT suppress telomerase activity, and inhibit growth of human colon cancer cells probably via induction of apoptosis and retardation of cell cycle. Additionally, combined use of telomerase ASODNs targeting both hTR and hTERT yields synergistic action selective for human colon cancer.

Oxidative stress and damage induced by abnormal free radical reactions and IgA nephropathy

Objective: To estimate the oxidative stress and oxidative damage induced by abnormal free radical reactions in IgA nephropathy (IgAN) patients' bodies. Methods: Seventy-two IgA N patients (IgANP) and 72 healthy adult volunteers (HAV) were enrolled in a random control study design, in which the levels of nitric oxide (NO) in plasma, lipoperoxide (LPO) in plasma and in erythrocytes, and vitamin C (VC), vitamin E (VE) and β-carotene (β-CAR) in plasma as well as the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) in erythrocytes were determined with spectrophotometric mothods. Results: Compared with the HAV group, the averages of NO in plasma, and LPO in plasma and in erythrocytes in the IgANP group were significantly increased (P＜0.0001), while those ofVC, VE and β-CAR in plasma as well as those of SOD, CAT and GPX in erythrocytes in the IgANP group were significantly decreased (P＜0.0001). Linear correlation analysis showed that with the increase of the values of NO, and LPO in plasma and in erythrocytes, and with the decrease of those ofVC, VE, β-CAR,SOD, CAT and GPX in the IgAN patients, the degree of histological damage of tubulointerstitial regions was increased gradually (P＜0.0001); and that with the prolongation of the duration of disease the values of NO, and LPO in plasma and erythrocytes were increased gradually, while those of VC, VE, β-CAR, SOD, CAT and GPX were decreased gradually (P＜0.005). The discriminatory correct rates of the above biochemical parameters reflecting oxidative damage of the IgAN patients were 73.8%-92.5%, and the correct rates for the HAV were 70.0%-91.3% when independent discriminant analysis was used; and the correct rate for the IgAN patients was increased to 98.8%, the correct rate for the HAV was increased to 100% when stepwise discriminant analysis was used. The above biochemical parameters' reliability coefficient (alpha) were used to estimate the oxidative damage of the IgAN patients as 0.8145, the standardized item alpha=0.9730, F=53273.5681, P＜0.0001. Conclusions: A series of free radical chain reactions caused serious pathological aggravation in the IgANP' bodies, thus resulting in oxidative damage in their bodies. In treating IgANP, therefore, it is necessary that suitable dose antioxidants should be supplemented to them so as to alleviate the oxidative damage in their bodies.

On the Dynamics of Controlled Diffusions

Treats of dynamical systems with finite number of degrees of freedom such that the time evolution of the configuration variables for given initial conditions can well be described by controlled diffusions.Two suitable forms of stochastic action associated with the controlled diffusions are introduced in the general framework of stochastic control theory.By discretizing the stochastic action,the dynamical equations for the controlled diffusions of the given systems are derived in terms of generalized coordinates.These equations,together with the continuity equation,describe exactly the probability approach of the diffusion motion.