ISO 9000标准中“要求”定义里“通常隐含的”需求或期望,如果按中文“不言而喻”的一词来理解与应用,从理论到实践有可能存在一定疏漏或瑕疵,还可能给组织带来一定的损失。对此,用中文“可以意会的”替代“不言而喻的”,不仅更贴近ISO ...ISO 9000标准中“要求”定义里“通常隐含的”需求或期望,如果按中文“不言而喻”的一词来理解与应用,从理论到实践有可能存在一定疏漏或瑕疵,还可能给组织带来一定的损失。对此,用中文“可以意会的”替代“不言而喻的”,不仅更贴近ISO 9000的原义,甚至更能凸显其作为国际质量标准的先进性以及引领与增值作用。展开更多
AIM: To study the expression of ether à go-go (Eag1) potassium channel in colorectal cancer and the relation- ship between their expression and clinico-pathological features. METHODS: The expression levels of Eag...AIM: To study the expression of ether à go-go (Eag1) potassium channel in colorectal cancer and the relation- ship between their expression and clinico-pathological features. METHODS: The expression levels of Eag1 protein were determined in 76 cancer tissues with paired non- cancerous matched tissues as well as 9 colorectal adenoma tissues by immunohistochemistry. Eag1 mRNA expression was detected in 13 colorectal cancer tissues with paired non-cancerous matched tissues and 4 colorectal adenoma tissues as well as two colorectal cancer cell lines (LoVo and HT-29) by reverse transcription PCR. RESULTS: The frequency of positive expression of Eag1 protein was 76.3% (58/76) and Eag1 mRNA was 76.9% (10/13) in colorectal cancer tissue. Expression level of Eag1 protein was dependent on the tumor size, lymphatic node metastasis, other organ metastases and Dukes’ stage (P < 0.05), while not dependent on age, sex, site and degree of differentiation. Eag1 protein and mRNA were negative in normal colorectal tissue, and absolutely negative in colorectal adenomas except that one case was positively stained for Eag1 protein. CONCLUSION: Eag1 protein and mRNA are aberrantly expressed in colorectal cancer and occasionally expressed in colorectal adenoma. The high frequency of expression of Eag1 in tumors and the restriction of normal expression to the brain suggest the potential of this protein for diagnostic, prognostic and therapeutic purposes.展开更多
Increasing time-spent online has amplified users' exposure to tile tilreat oI miormanon leakage. Although existing security systems (such as firewalls and intrusion detection systems) can satisfy most of the securi...Increasing time-spent online has amplified users' exposure to tile tilreat oI miormanon leakage. Although existing security systems (such as firewalls and intrusion detection systems) can satisfy most of the security requirements of network administrators, they are not suitable for detecting the activities of applying the HTTP-tunnel technique to steal users' private information. This paper focuses on a network behavior-based method to address the limitations of the existing protection systems. At first, it analyzes the normal network behavior pattern over HTI'P traffic and select four features. Then, it pres- ents an anomaly-based detection model that applies a hierarchical clustering technique and a scoring mechanism. It also uses real-world data to validate that the selected features are useful. The experiments have demonstrated that the model could achieve over 93% hit-rate with only about 3% false- positive rate. It is regarded confidently that the approach is a complementary technique to the existing security systems.展开更多
This paper proposes Steepest Decreasing Constant Modulus Algorithm (SDCMA) detection in frequency dornain for MultiCarrier Direct Sequence-Code Division Multiple Access (MC DS-CDMA) systems. The proposed algorithm...This paper proposes Steepest Decreasing Constant Modulus Algorithm (SDCMA) detection in frequency dornain for MultiCarrier Direct Sequence-Code Division Multiple Access (MC DS-CDMA) systems. The proposed algorithm is used to equalize independent ladings of all subcarriers. At the same time we compare the SDCMA blind detection with subspace-based Minimum Mean-Squared Error (MMSE) detection. The simulation results show that the pertbrmance of SDCMA blind detection is superior to that of subspace-based MMSE detection and the complexity of the former is much lower than that of the latter.展开更多
The research intends to solve the problem of the occupation of bandwidth of local network by abnormal traffic which affects normal user's network behaviors.Firstly,a new algorithm in this paper named danger-theory...The research intends to solve the problem of the occupation of bandwidth of local network by abnormal traffic which affects normal user's network behaviors.Firstly,a new algorithm in this paper named danger-theory-based abnormal traffic detection was presented.Then an advanced ID3 algorithm was presented to classify the abnormal traffic.Finally a new model of anomaly traffic detection was built upon the two algorithms above and the detection results were integrated with firewall.The firewall limits the bandwidth based on different types of abnormal traffic.Experiments show the outstanding performance of the proposed approach in real-time property,high detection rate,and unsupervised learning.展开更多
In this paper, the authors explore the potential of several popular equalization techniques while overcoming their disadvantages. First, extensive literature survey on equalization is conducted. The focus is on popula...In this paper, the authors explore the potential of several popular equalization techniques while overcoming their disadvantages. First, extensive literature survey on equalization is conducted. The focus is on popular linear equalization algorithms such as the conventional least mean square (LMS ) algorithm, the recursive least squares ( RLS ) algorithm, the filtered X LMS algorithm and their development. To overcome the slow convergence problem while keeping the simplicity of the LMS based algorithms, an H 2 optimal initialization is proposed.展开更多
A multidisciplinary optimization was conducted to simultaneously improve the efficiency and reduce the radial force of a single-channel pump for wastewater treatment. A hybrid multi-objective evolutionary algorithm wa...A multidisciplinary optimization was conducted to simultaneously improve the efficiency and reduce the radial force of a single-channel pump for wastewater treatment. A hybrid multi-objective evolutionary algorithm was coupled with a surrogate model to optimize the geometry of the single-channel pump volute. Steady and unsteady Reynolds-averaged Navier-Stokes equations with a shear stress transport turbulence model were discretized using finite volume approximations and were then solved on tetrahedral grids to analyze the flow in the single-channel pump. The three objective functions represented the total efficiency, the sweep area of the radial force during one revolution, and the distance of the mass center of sweep area from the origin while the two design variables were related to the cross-sectional area of the internal flow of the volute. Latin hypercube sampling was employed to generate twelve design points within the design space, and response surface approximation models were constructed as surrogate models for the objectives based on the values of the objective function at the given design points. A fast non-dominated sorting genetic algorithm for local search was coupled with the surrogate models to determine the global Pareto-optimal solutions. The trade-off between the objectives was determined and was described in terms of the Pareto-optimal solutions. The results of the multi-objective optimization showed that the optimum design simultaneously improved the efficiency and reduced the radial force relative to those of the reference design.展开更多
Interannual variations in the surface and subsurface tropical Indian Ocean were studied using HadlSST and SODA datasets. Wind and heat flux datasets were used to discuss the mechanisms for these variations. Our result...Interannual variations in the surface and subsurface tropical Indian Ocean were studied using HadlSST and SODA datasets. Wind and heat flux datasets were used to discuss the mechanisms for these variations. Our results indicate that the surface and subsurface variations of the tropical Indian Ocean during Indian Ocean Dipole (IOD) events are significantly different. A prominent characteristic of the eastern pole is the SSTA rebound after a cooling process, which does not take place at the subsurface layer. In the western pole, the surface anomalies last longer than the subsurface anomalies. The subsurface anomalies are strongly correlated with ENSO, while the relationship between the surface anomalies and ENSO is much weaker. And the subsurface anomalies of the two poles are negatively correlated while they are positively correlated at the surface layer. The wind and surface heat flux analysis suggests that the thermocline depth variations are mainly determined by wind stress fields, while the heat flux effect is important on SST.展开更多
Theories with ingredients like the Higgs mechanism, gravitons, and inflaton fields rejuvenate the idea that relativistic kinematics is dynamically emergent. Eternal inflation treats the Hubble constant H as depending ...Theories with ingredients like the Higgs mechanism, gravitons, and inflaton fields rejuvenate the idea that relativistic kinematics is dynamically emergent. Eternal inflation treats the Hubble constant H as depending on location. Microscopic dynamics implies that H is over much smaller lengths than pocket universes to be understood as a local space reproduction rate. We illustrate this via discussing that even exponential inflation in TeV-gravity is slow on the relevant time scale. In our on small scales inhomogeneous cosmos, a reproduction rate H depends on position. We therefore discuss Einstein-Strauss vacuoles and a Lindquist-Wheeler like lattice to connect the local rate properly with the scaling of an expanding cosmos. Consistency allows H to locally depend on Weyl curvature similar to vacuum polarization. We derive a proportionality constant known from Kepler's third law and discuss the implications for the finiteness of the cosmological constant.展开更多
The Northern Indian Ocean (NIO) sea surface temperature (SST) warming, associated with the E1 Nifio/Southern Oscillations (ENSO) and the Indian Ocean Dipole (IOD) mode, is investigated using the International ...The Northern Indian Ocean (NIO) sea surface temperature (SST) warming, associated with the E1 Nifio/Southern Oscillations (ENSO) and the Indian Ocean Dipole (IOD) mode, is investigated using the International Comprehensive Ocean-Atmosphere Data Set (ICOADS) monthly data for the period 1979-2010. Statistical analy- ses are used to identify respective contribution from ENSO and IOD. The results indicate that the first NIO SST warming in September-November is associated with an IOD event, while the second NIO SST warming in spring-summer following the mature phase of ENSO is associated with an ENSO event. In the year that IOD co-occurred with ENSO, NIO SST warms twice, rising in the ENSO developing year and decay year. Both short- wave radiation and latent heat flux contribute to the NIO SST variation. The change in shortwave radiation is due to the change in cloudiness. A cloud-SST feedback plays an important role in NIO SST warming. The latent heat flux is related to the change in monsoonal wind. In the first NIO warming, the SST anomaly is mainly due to the change in the latent heat flux. In the second NIO warming, both factors are important.展开更多
Carbon monoxide (CO) intoxication is one of the most common types of poisoning in the modem world. To better tailor messages and communication needs to the public, a perception survey of CO and his risk was conducte...Carbon monoxide (CO) intoxication is one of the most common types of poisoning in the modem world. To better tailor messages and communication needs to the public, a perception survey of CO and his risk was conducted among the population of Rabat-Sale-Zemmour-Zaer. The authors included 400 people in this survey. The demographic characteristics of the respondents consisted of: 85.0% female, 92.9% adults, 29.7% had a high level of education, 49.6% unemployed, 89.5% were home owners and 53.9% lived in apartments. Water heaters were present in the homes of 91.0% of respondents and 6.5% of them used gas. Gas was used as fuel in 45.4% of cases. For water heaters, 20.8% had an exhaust duct, 9.9% were serviced regularly and 47.5% were installed in a well ventilated area. Regarding the media, television was the medium that allowed 73.4% of the CO to know, regardless of age, sex and level of education among the 94.3% of who ever heard of this deadly gas before the survey.展开更多
This paper presents numerical studies on the effects of atmospheric pressure fluctuations on hill-side coal fires and their surface anomalies. Based on the single-particle reaction–diffusion model, a formula to estim...This paper presents numerical studies on the effects of atmospheric pressure fluctuations on hill-side coal fires and their surface anomalies. Based on the single-particle reaction–diffusion model, a formula to estimate oxygen consumption rate at high temperature controlled by oxygen transport is proposed.Daily fluctuant atmospheric pressure was imposed on boundaries, including the abandoned gallery and cracks. Simulated results show that the effects of atmospheric pressure fluctuations on coal fires and surface anomalies depend on two factors: the fluctuant amplitude and the pressure difference between inlet(s) and outlet(s) of the air ventilation system. If the pressure difference is close to the fluctuant amplitude, atmospheric pressure fluctuations greatly enhance gas flow motion and temperatures of the combustion zone and outtake(s). If the pressure difference is much larger than the fluctuant amplitude, atmospheric pressure fluctuations exert no impact on underground coal fires and surface anomalies.展开更多
This paper is devoted to application of ordinary kriging method in Choghart north anomaly iron ore deposit in Yazd province, Iran. In order to estimate the deposit, 2329 input data gained from 26 boreholes were used. ...This paper is devoted to application of ordinary kriging method in Choghart north anomaly iron ore deposit in Yazd province, Iran. In order to estimate the deposit, 2329 input data gained from 26 boreholes were used. Fe grade was selected as the major regional variable on which the present research has focused. All of the available data were changed to 12.5 m composites so that statistical regularization could be reached. Studies indicated that iron grade input data had single-population characteristics. To carry out ordinary kriging, a spherical model was fitted over empirical variogram. Then the model was verified through cross validation method and proved to be valid with a coherence coefficient of 0.773 between the estimated and real data. Plotting the empirical variogram in different directions showed no geometric anisotropy for the deposit. To estimate the Iron grade, ordinary kriging method was used according to which, all of the exploitable blocks with dimensions 20 m x 20 m x 12.5 m were block esti- mated within the estimation space. Finally tonnage-grade curve has been drawn and reserve classified into measured, indicated and inferred.展开更多
文摘AIM: To study the expression of ether à go-go (Eag1) potassium channel in colorectal cancer and the relation- ship between their expression and clinico-pathological features. METHODS: The expression levels of Eag1 protein were determined in 76 cancer tissues with paired non- cancerous matched tissues as well as 9 colorectal adenoma tissues by immunohistochemistry. Eag1 mRNA expression was detected in 13 colorectal cancer tissues with paired non-cancerous matched tissues and 4 colorectal adenoma tissues as well as two colorectal cancer cell lines (LoVo and HT-29) by reverse transcription PCR. RESULTS: The frequency of positive expression of Eag1 protein was 76.3% (58/76) and Eag1 mRNA was 76.9% (10/13) in colorectal cancer tissue. Expression level of Eag1 protein was dependent on the tumor size, lymphatic node metastasis, other organ metastases and Dukes’ stage (P < 0.05), while not dependent on age, sex, site and degree of differentiation. Eag1 protein and mRNA were negative in normal colorectal tissue, and absolutely negative in colorectal adenomas except that one case was positively stained for Eag1 protein. CONCLUSION: Eag1 protein and mRNA are aberrantly expressed in colorectal cancer and occasionally expressed in colorectal adenoma. The high frequency of expression of Eag1 in tumors and the restriction of normal expression to the brain suggest the potential of this protein for diagnostic, prognostic and therapeutic purposes.
基金Supported by the National Natural Science Foundation of China(No.61070185,61003261)the Knowledge Innovation Program of the Chinese Academy of Sciences(No.XDA06030200)
文摘Increasing time-spent online has amplified users' exposure to tile tilreat oI miormanon leakage. Although existing security systems (such as firewalls and intrusion detection systems) can satisfy most of the security requirements of network administrators, they are not suitable for detecting the activities of applying the HTTP-tunnel technique to steal users' private information. This paper focuses on a network behavior-based method to address the limitations of the existing protection systems. At first, it analyzes the normal network behavior pattern over HTI'P traffic and select four features. Then, it pres- ents an anomaly-based detection model that applies a hierarchical clustering technique and a scoring mechanism. It also uses real-world data to validate that the selected features are useful. The experiments have demonstrated that the model could achieve over 93% hit-rate with only about 3% false- positive rate. It is regarded confidently that the approach is a complementary technique to the existing security systems.
基金Supported by the National Natural Science Foundation of China (No.60472104).
文摘This paper proposes Steepest Decreasing Constant Modulus Algorithm (SDCMA) detection in frequency dornain for MultiCarrier Direct Sequence-Code Division Multiple Access (MC DS-CDMA) systems. The proposed algorithm is used to equalize independent ladings of all subcarriers. At the same time we compare the SDCMA blind detection with subspace-based Minimum Mean-Squared Error (MMSE) detection. The simulation results show that the pertbrmance of SDCMA blind detection is superior to that of subspace-based MMSE detection and the complexity of the former is much lower than that of the latter.
基金Shanghai Education Commission Foundation for Excellent Young High Education Teachers,China(No.xqz05001No.YYY-07008)
文摘The research intends to solve the problem of the occupation of bandwidth of local network by abnormal traffic which affects normal user's network behaviors.Firstly,a new algorithm in this paper named danger-theory-based abnormal traffic detection was presented.Then an advanced ID3 algorithm was presented to classify the abnormal traffic.Finally a new model of anomaly traffic detection was built upon the two algorithms above and the detection results were integrated with firewall.The firewall limits the bandwidth based on different types of abnormal traffic.Experiments show the outstanding performance of the proposed approach in real-time property,high detection rate,and unsupervised learning.
文摘In this paper, the authors explore the potential of several popular equalization techniques while overcoming their disadvantages. First, extensive literature survey on equalization is conducted. The focus is on popular linear equalization algorithms such as the conventional least mean square (LMS ) algorithm, the recursive least squares ( RLS ) algorithm, the filtered X LMS algorithm and their development. To overcome the slow convergence problem while keeping the simplicity of the LMS based algorithms, an H 2 optimal initialization is proposed.
文摘A multidisciplinary optimization was conducted to simultaneously improve the efficiency and reduce the radial force of a single-channel pump for wastewater treatment. A hybrid multi-objective evolutionary algorithm was coupled with a surrogate model to optimize the geometry of the single-channel pump volute. Steady and unsteady Reynolds-averaged Navier-Stokes equations with a shear stress transport turbulence model were discretized using finite volume approximations and were then solved on tetrahedral grids to analyze the flow in the single-channel pump. The three objective functions represented the total efficiency, the sweep area of the radial force during one revolution, and the distance of the mass center of sweep area from the origin while the two design variables were related to the cross-sectional area of the internal flow of the volute. Latin hypercube sampling was employed to generate twelve design points within the design space, and response surface approximation models were constructed as surrogate models for the objectives based on the values of the objective function at the given design points. A fast non-dominated sorting genetic algorithm for local search was coupled with the surrogate models to determine the global Pareto-optimal solutions. The trade-off between the objectives was determined and was described in terms of the Pareto-optimal solutions. The results of the multi-objective optimization showed that the optimum design simultaneously improved the efficiency and reduced the radial force relative to those of the reference design.
基金supported by the National Natural Science Foundation of China(Grant Nos.40876001 and40890152)the Program for New Century Excellent Talents in University(Grant No.NCET-08-0510)the State Key Development Program for National Basic Research Program of China under contract(Grant No.2007CB-411803)
文摘Interannual variations in the surface and subsurface tropical Indian Ocean were studied using HadlSST and SODA datasets. Wind and heat flux datasets were used to discuss the mechanisms for these variations. Our results indicate that the surface and subsurface variations of the tropical Indian Ocean during Indian Ocean Dipole (IOD) events are significantly different. A prominent characteristic of the eastern pole is the SSTA rebound after a cooling process, which does not take place at the subsurface layer. In the western pole, the surface anomalies last longer than the subsurface anomalies. The subsurface anomalies are strongly correlated with ENSO, while the relationship between the surface anomalies and ENSO is much weaker. And the subsurface anomalies of the two poles are negatively correlated while they are positively correlated at the surface layer. The wind and surface heat flux analysis suggests that the thermocline depth variations are mainly determined by wind stress fields, while the heat flux effect is important on SST.
文摘Theories with ingredients like the Higgs mechanism, gravitons, and inflaton fields rejuvenate the idea that relativistic kinematics is dynamically emergent. Eternal inflation treats the Hubble constant H as depending on location. Microscopic dynamics implies that H is over much smaller lengths than pocket universes to be understood as a local space reproduction rate. We illustrate this via discussing that even exponential inflation in TeV-gravity is slow on the relevant time scale. In our on small scales inhomogeneous cosmos, a reproduction rate H depends on position. We therefore discuss Einstein-Strauss vacuoles and a Lindquist-Wheeler like lattice to connect the local rate properly with the scaling of an expanding cosmos. Consistency allows H to locally depend on Weyl curvature similar to vacuum polarization. We derive a proportionality constant known from Kepler's third law and discuss the implications for the finiteness of the cosmological constant.
基金supported by the National Basic Research Program of China(973 Program,2012CB955603 &2010 CB950302)the Knowledge Innovation Program of the Chinese Academy of Sciences(XDA05090404)the National Natural Science Foundation of China(41149908)
文摘The Northern Indian Ocean (NIO) sea surface temperature (SST) warming, associated with the E1 Nifio/Southern Oscillations (ENSO) and the Indian Ocean Dipole (IOD) mode, is investigated using the International Comprehensive Ocean-Atmosphere Data Set (ICOADS) monthly data for the period 1979-2010. Statistical analy- ses are used to identify respective contribution from ENSO and IOD. The results indicate that the first NIO SST warming in September-November is associated with an IOD event, while the second NIO SST warming in spring-summer following the mature phase of ENSO is associated with an ENSO event. In the year that IOD co-occurred with ENSO, NIO SST warms twice, rising in the ENSO developing year and decay year. Both short- wave radiation and latent heat flux contribute to the NIO SST variation. The change in shortwave radiation is due to the change in cloudiness. A cloud-SST feedback plays an important role in NIO SST warming. The latent heat flux is related to the change in monsoonal wind. In the first NIO warming, the SST anomaly is mainly due to the change in the latent heat flux. In the second NIO warming, both factors are important.
文摘Carbon monoxide (CO) intoxication is one of the most common types of poisoning in the modem world. To better tailor messages and communication needs to the public, a perception survey of CO and his risk was conducted among the population of Rabat-Sale-Zemmour-Zaer. The authors included 400 people in this survey. The demographic characteristics of the respondents consisted of: 85.0% female, 92.9% adults, 29.7% had a high level of education, 49.6% unemployed, 89.5% were home owners and 53.9% lived in apartments. Water heaters were present in the homes of 91.0% of respondents and 6.5% of them used gas. Gas was used as fuel in 45.4% of cases. For water heaters, 20.8% had an exhaust duct, 9.9% were serviced regularly and 47.5% were installed in a well ventilated area. Regarding the media, television was the medium that allowed 73.4% of the CO to know, regardless of age, sex and level of education among the 94.3% of who ever heard of this deadly gas before the survey.
文摘This paper presents numerical studies on the effects of atmospheric pressure fluctuations on hill-side coal fires and their surface anomalies. Based on the single-particle reaction–diffusion model, a formula to estimate oxygen consumption rate at high temperature controlled by oxygen transport is proposed.Daily fluctuant atmospheric pressure was imposed on boundaries, including the abandoned gallery and cracks. Simulated results show that the effects of atmospheric pressure fluctuations on coal fires and surface anomalies depend on two factors: the fluctuant amplitude and the pressure difference between inlet(s) and outlet(s) of the air ventilation system. If the pressure difference is close to the fluctuant amplitude, atmospheric pressure fluctuations greatly enhance gas flow motion and temperatures of the combustion zone and outtake(s). If the pressure difference is much larger than the fluctuant amplitude, atmospheric pressure fluctuations exert no impact on underground coal fires and surface anomalies.
基金the National Natural Science Foundation of China (Nos. 40772192 and 40372123)the Key Laboratory Project of Deep Rock Mechanics (No.PD1011)
文摘This paper is devoted to application of ordinary kriging method in Choghart north anomaly iron ore deposit in Yazd province, Iran. In order to estimate the deposit, 2329 input data gained from 26 boreholes were used. Fe grade was selected as the major regional variable on which the present research has focused. All of the available data were changed to 12.5 m composites so that statistical regularization could be reached. Studies indicated that iron grade input data had single-population characteristics. To carry out ordinary kriging, a spherical model was fitted over empirical variogram. Then the model was verified through cross validation method and proved to be valid with a coherence coefficient of 0.773 between the estimated and real data. Plotting the empirical variogram in different directions showed no geometric anisotropy for the deposit. To estimate the Iron grade, ordinary kriging method was used according to which, all of the exploitable blocks with dimensions 20 m x 20 m x 12.5 m were block esti- mated within the estimation space. Finally tonnage-grade curve has been drawn and reserve classified into measured, indicated and inferred.