道统论的突破与《宋元学案》的思想史构建——兼论“宋初三先生”思想史地位的确立

黄宗羲、黄百家父子基于一本万殊的思想史观,在《宋元学案》中突破了《宋史·道学传》以程朱理学为正统的道统思想史视域,主张废除"道学传"而统归"儒林传",体现了和会朱、陆、浙学等各派、重视自得创见的思想立场。基于此立场,黄氏父子高度评价并确立了"宋初三先生"作为宋学开山和道学先驱的思想史地位,为之设立学案并将其置于《宋元学案》的开端。全祖望基于人品与学问兼顾的史学家立场,只以胡瑗、孙复二人作为宋学开山,并进一步拓宽了黄氏父子道(道学)、儒(儒林)合一的思想史视域,兼容并包道、儒、文(文艺)等各派人物,从而填补了宋元儒学史上的诸多空白,完备了《宋元学案》中的思想史构建,体现了去短集长的会通思想史观。

Amelanotic malignant melanoma of the esophagus:Report of two cases with immunohistochemical and molecular genetic study of KIT and PDGFRA

The author reports herein two cases of amelanotic malignant melanoma of the esophagus. Case 1 is an 87-year-old woman who was admitted to our hospital because of nausea and vomiting. Endoscopic examination revealed an ulcerated tumor of the distal esophagus, and a biopsy was taken. The biopsy showed malignant polygonal and spindle cells. No melanin pigment was recognized. Immunohistochemically, the tumor cells were positive for melanosome （HMB45）, S100 protein, KIT and Platelet derived growth factor receptor-α （PDG- FRA）. The patient was treated by chemotherapy and radiation, but died of systemic metastasis 12 mo after the presentation. Case 2 is a 56-year-old man presenting with dysphagia. Endoscopic examination revealed a polypoid tumor in the middle esophagus, and a biopsy was obtained. The biopsy showed malignant spindle cells without melanin pigment. Immunohistochemically, the tumor cells were positively labeled for melanosome,S100 protein, KIT and PDGFRA. The patient refused operation, and was treated by palliative chemotherapy and radiation. He died of metastasis 7 mo aEer the admission. In both cases, molecular genetic analyses of gene （exons 9, 11, 13 and 17） and PDGFRA gene （exons 12 and 18） were performed by the PCR direct sequencing method, which showed no mutations of KIT and PDGFRA genes. This is the first report of esophageal malignant melanoma with an examination of the expression of KIT and PDGFRA and the mutational status of K/T and PDGFRA genes.

Morphological,kinetic,membrane biochemical and genetic aspects of intestinal enteroplasticity

The process of intestinal adaptation("enteroplasticity") is complex and multifaceted.Although a number of trophic nutrients and non-nutritive factors have been identified in animal studies,successful,reproducible clinical trials in humans are awaited.Understanding mechanisms underlying this adaptive process may direct research toward strategies that maximize intestinal function and impart a true clinical benefit to patients with short bowel syndrome,or to persons in whom nutrient absorption needs to be maximized.In this review,we consider the morphological,kinetic and membrane biochemical aspects of enteroplasticity,focus on the importance of nutritional factors,provide an overview of the many hormones that may alter the adaptive process,and consider some of the possible molecular profiles.While most of the data is derived from rodent studies,wherever possible,the results of human studies of intestinal enteroplasticity are provided.

Design of a multi-channel free space optical interconnection component

A multi-channel free space optical interconnection component, fiber optic rotary joint, was designed using a Dove prism. When the Dove prism is rotated an angle of at around the longitudinal axis, the image rotates an angle of 2 at. The optical interconnection component consists of the signal transmission system, Dove prim and driving mechanism. The planetary gears are used to achieve the speed ratio of 2：l between the total optical interconnection component and the Dove prism. The Clenses are employed to couple different optical signals in the signal transmission system. The coupling loss between the receiving fiber of stationary part and the transmitting fiber of rotary part is measured.

Investigations and thoughts of the ethics in genetic discrimination

A questionnaire research in ethics was conducted to get the view of students of medical universities in Shanghai on genomics and genetic discrimination. We find that 66% respondents indicated their willingness to understand the genetic information and 79% of respondents mind their own genetic information be aware of by other people. In contrast, 77% of the respondents believe that medical organization are not able to protect personal genetic information from disclose. Hence, it is significant to take some measures to preserve citizen's genetic information privacy. Depending on our results, we put forward our suggestion to this problem.

Role of genetics in the diagnosis and prognosis of Crohn's disease

Considering epidemiological,genetic and immunological data,we can conclude that the inflammatory bowel diseases are heterogeneous disorders of multifactorial etiology in which hereditability and environment interact to produce the disease.It is probable that patients have a genetic predisposition for the development of the disease coupled with disturbances in immunoregulation.Several genes have been so far related to the diagnosis of Crohn's disease.Those genes are related to innate pattern recognition receptors,to epithelial barrier homeostasis and maintenance of epithelial barrier integrity,to autophagy and to lymphocyte differentiation.So far,the most strong and replicated associations with Crohn's disease have been done with NOD2,IL23R and ATG16L1 genes.Many genes have so far been implicated in prognosis of Crohn's disease and many attempts have been made to classify genetic profiles in Crohn's disease.CARD15 seems not only a susceptibility gene,but also a disease-modifier gene for Crohn's disease.Enriching our understanding on Crohn's disease genetics is important but when combining genetic data with functional data the outcome could be of major importance to clinicians.

Q-learning-based energy transmission scheduling over a fading channel

To solve the problem of energy transmission in the Internet of Things(IoTs),an energy transmission schedule over a Rayleigh fading channel in the energy harvesting system(EHS)with a dedicated energy source(ES)is considered.According to the channel state information(CSI)and the battery state,the charging duration of the battery is determined to jointly minimize the energy consumption of ES,the battery's deficit charges and overcharges during energy transmission.Then,the joint optimization problem is formulated using the weighted sum method.Using the ideas from the Q-learning algorithm,a Q-learning-based energy scheduling algorithm is proposed to solve this problem.Then,the Q-learning-based energy scheduling algorithm is compared with a constant strategy and an on-demand dynamic strategy in energy consumption,the battery's deficit charges and the battery's overcharges.The simulation results show that the proposed Q-learning-based energy scheduling algorithm can effectively improve the system stability in terms of the battery's deficit charges and overcharges.

Teleportation of Multi-ionic GHZ States and Arbitrary Bipartite Ionic State via Linear Optics

We present a scheme for teleportation of multi-ionic GHZ states and arbitrary bipartite ionic state only by single-qubit measurements via linear optical elements. In our scheme, we avoid the difficulty of joint measurement and synchronizing the arrival time of the two scattered photons, which are faced by previous schemes. So our scheme can be realized easily within current experimental technology.

A Learning-Based Channel Model for Synergetic Transmission Technology

It is extensively approved that Channel State Information(CSI) plays an important role for synergetic transmission and interference management. However, pilot overhead to obtain CSI with enough precision is a significant issue for wireless communication networks with massive antennas and ultra-dense cell. This paper proposes a learning- based channel model, which can estimate, refine, and manage CSI for a synergetic transmission system. It decomposes the channel impulse response into multiple paths, and uses a learning-based algorithm to estimate paths' parameters without notable degradation caused by sparse pilots. Both indoor measurement and outdoor measurement are conducted to verify the feasibility of the proposed channel model preliminarily.

Managing Our Past, Managing Our Future： Is there a ＂Right＂ Way of Remembrance？

In the spring of 1944, the Auschwitz-Birkenau death factory was still a top secret of the Third Reich and the Nazis used numerous ploys to entice their prospective victims into it. On April 7, 1944, two Slovak Jewish prisoners, Rudolf Vrba and Alfred Wetzler managed to escape Auschwitz-Birkenau and reveal its secrets. They further warned that specific arrangements had been made in the camp for the annihilation of the Hungarian Jews. The precious information was disseminated without delay to the Western world. It is not clear whether it reached the prospective victims： All boarded in good faith the ＂resettlement trains＂ that carried them to the Auschwitz-Birkenau death camp, where most were immediately gassed. This specific story has been missing from most Israeli history textbooks in Hebrew. Following Winter＇s （2006） thesis, this paper tries to trace some of the official manipulation that were made in shaping the ＂right＂ form of remembrance.

Conductive Channel for Energy Transmission

Laser spark obtained by using a conical optics is much more appropriate to form conducting channels in atmosphere. Only two types of lasers are actively considered to be used in forming high-conductivity channels in atmosphere, controlled by laser spark： pulsed sub-microsecond gas and chemical lasers （CO2, DF （deuterium fluoride））, short pulse solid-state and UV （ultraviolet） lasers. Main advantage of short pulse lasers is their ability in forming of super long ionized channels with a characteristic diameter of- 100 mm in atmosphere along the beam propagation direction. At estimated electron densities below 1,016 cm3 in these filaments and laser wavelengths in the range of 0.5-1.0 mm, the plasma barely absorbs laser radiation. In this case, the length of the track composed of many filaments is determined by the laser intensity and may reach many kilometers at a femtosecond pulse energy of-100 mJ. However, these lasers could not be used to form high-conductivity long channels in atmosphere. The ohmic resistance of this type a conducting channels turned out to be very high, and the gas in the channels could not be strongly heated （〈 1 J）. An electric breakdown controlled by radiation of femtosecond solid-state laser was implemented in only at a length of 3 m with a voltage of 2 MV across the discharge gap （670 kV/m）. Not so long ago scientific group from P.N. Lebedev physical institute has improved that result, the discharge gap （-1m） had been broken under KrF laser irradiation when switching high-voltage （up to 390 kV/m） electric discharge by 100-ns UV pulses. Our previous result -16 m long conducting channel controlled by a laser spark at the voltage -3 MV was obtained more than 20 years ago in Russia and Japan by using pulsed CO2 laser with energy -0.5 kJ. An average electric field strength was 〈 190 kV/m. It is still too much for efficient applications.

Electrochemical creation of surface charge transfer channels on photoanodes for efficient solar water splitting

Electrochemical treatment is a popular and efficient method for improving the photoelectrochemical performance of water‐splitting photoelectrodes.In our previous study,the electrochemical activation of Mo‐doped BiVO_(4) electrodes was ascribed to the removal of MoO_(x) segregations,which are considered to be surface recombination centers for photoinduced electrons and holes.However,this proposed mechanism cannot explain why activated Mo‐doped BiVO_(4) electrodes gradually lose their activity when exposed to air.In this study,based on various characterizations,it is suggested that electrochemical treatment not only removes partial MoO_(x) segregations but also initiates the formation of H_(y)MoO_(x) surface defects,which provide charge transfer channels for photogenerated holes.The charge separation of the Mo‐doped BiVO_(4) electrode was significantly enhanced by these charge transfer channels.This study offers a new insight into the electrochemical activation of Mo‐doped BiVO_(4) photoanodes,and the new concept of surface charge transfer channels,a long overlooked factor,will be valuable for the development of other(photo)electrocatalytic systems.

Steric paper based ratio-type electrochemical biosensor with hollow-channel for sensitive detection of Zn2+

The construction of flexible platform possessing the functions of immobilizing, separating, rinsing, and high-throughput analysis plays a significant role in biological and clinical research. Herein, hollow- channel technique was integrated with lab-on-paper for the simultaneous determination of two different concentrations of Zn2＋ based on the origami principle, in which microfiuidic channels were first patterned on a cellulose paper using commercial solid-state wax printer. Hollow-channels were created by laser cutting method as the role of both injecting ending and reaction tank. After screen printing three elec- trodes system, the resulting planar paper sheets were then folded into steric structures and functional- ized by in-situ synthesized reduced graphene oxide. As a proof-of-concept, such lab-on-paper device was employed in the ratiometric electrochemical monitoring of zinc ion from the environment and HepG2 cells extract, by combining with co-catalysis of porous metal-organic frameworks and hemin/ G-quadruplex toward H202 in the linear range of 0.1-7,000 nmol/L. The results indicated that integrating hollow-channel with steric lab-on-paper offered a new methodological approach for the development of metal ions monitoring research. It is believed that it could be useful for various point-of-care related research fields, such as, on-site environmental monitoring, food safety, and disease diagnosis.

High-efficiency room temperature phosphorescence from amorphous metal-free copolymers

Photofunctional materials with room-temperature phosphorescence（RTP）commonly appeared in expensive metal-coordination complexes and rare-earth-based compounds.Recently,the metal-free organic RTP materials have been paid growing attention from scientific community because of the ease of molecular design,low cost as well as potential applications in molecular switches,chemical sensors and biological imaging.To date,efficient RTP materials with high quantum yield are still very limited due to the T_1-S_0 spinforbidden process and weak spin-orbital coupling.Current mechanism based on crystallization-induced or aggregationinduced phosphorescence may serve as an effective way to enhance the RTP[1,2];