目的:回顾性评价金叶败毒颗粒与连花清瘟胶囊治疗新冠重症患者的临床疗效。方法:选取2020年1月18日~2020年4月26日于华中科技大学同济医学院附属同济医院接受过金叶败毒颗粒或连花清瘟胶囊治疗≥5 d的新冠重症患者出院病历资料577例,按...目的:回顾性评价金叶败毒颗粒与连花清瘟胶囊治疗新冠重症患者的临床疗效。方法:选取2020年1月18日~2020年4月26日于华中科技大学同济医学院附属同济医院接受过金叶败毒颗粒或连花清瘟胶囊治疗≥5 d的新冠重症患者出院病历资料577例,按照治疗方法不同分为金叶败毒治疗组(159例)和连花清瘟治疗组(418例)。将以上患者按年龄、性别、基础疾病和接受治疗方式相同的标准进行1∶1匹配,采用倾向性评分匹配法平衡混杂因素,获得组间协变量均衡的样本,在此基础上比较两组患者的临床治愈率、住院时长、核酸转阴时间、胸部CT改善时间和用药前后实验室检查结果。结果:经倾向性评分匹配,两组各纳入157例重症患者,基线特征具有可比性。金叶败毒组与连花清瘟组在临床治愈率(93.63%vs 90.45%,P>0.05)、住院时长(27 d vs 32 d,P>0.05)、核酸转阴时间(24 d vs 27 d,P>0.05)和胸部CT改善时间(30 d vs 31 d,P>0.05)等方面无显著性差异。与连花清瘟相比,服用金叶败毒颗粒能显著提高重症患者的淋巴细胞水平(0.31×10^(9)/L vs 0.22×109/L,P<0.05)。结论:与连花清瘟胶囊相比,金叶败毒颗粒可能在提高新冠重症患者淋巴细胞方面具有优势。展开更多
Chrysosplenium fallax Koldaeva,recently discovered and collected in Yanji,Jilin Province,repre-sents a newly recorded species of Saxifragaceae in China.This species,native to the Russian Far East,was first described a...Chrysosplenium fallax Koldaeva,recently discovered and collected in Yanji,Jilin Province,repre-sents a newly recorded species of Saxifragaceae in China.This species,native to the Russian Far East,was first described as a new species in 2021.Based on precise field investigations and specimen examination,we provide a comprehensive description of C.fallax and its seed micromorphology.Phylogenetic analysis based on chloroplast genomes of 45 Chrysosplenium species confirmed the systematic position of C.fallax in Chrysosplenium.Voucher specimens were deposited in the Herbarium of South-Central Minzu University(HSN).展开更多
文摘目的:回顾性评价金叶败毒颗粒与连花清瘟胶囊治疗新冠重症患者的临床疗效。方法:选取2020年1月18日~2020年4月26日于华中科技大学同济医学院附属同济医院接受过金叶败毒颗粒或连花清瘟胶囊治疗≥5 d的新冠重症患者出院病历资料577例,按照治疗方法不同分为金叶败毒治疗组(159例)和连花清瘟治疗组(418例)。将以上患者按年龄、性别、基础疾病和接受治疗方式相同的标准进行1∶1匹配,采用倾向性评分匹配法平衡混杂因素,获得组间协变量均衡的样本,在此基础上比较两组患者的临床治愈率、住院时长、核酸转阴时间、胸部CT改善时间和用药前后实验室检查结果。结果:经倾向性评分匹配,两组各纳入157例重症患者,基线特征具有可比性。金叶败毒组与连花清瘟组在临床治愈率(93.63%vs 90.45%,P>0.05)、住院时长(27 d vs 32 d,P>0.05)、核酸转阴时间(24 d vs 27 d,P>0.05)和胸部CT改善时间(30 d vs 31 d,P>0.05)等方面无显著性差异。与连花清瘟相比,服用金叶败毒颗粒能显著提高重症患者的淋巴细胞水平(0.31×10^(9)/L vs 0.22×109/L,P<0.05)。结论:与连花清瘟胶囊相比,金叶败毒颗粒可能在提高新冠重症患者淋巴细胞方面具有优势。
文摘Chrysosplenium fallax Koldaeva,recently discovered and collected in Yanji,Jilin Province,repre-sents a newly recorded species of Saxifragaceae in China.This species,native to the Russian Far East,was first described as a new species in 2021.Based on precise field investigations and specimen examination,we provide a comprehensive description of C.fallax and its seed micromorphology.Phylogenetic analysis based on chloroplast genomes of 45 Chrysosplenium species confirmed the systematic position of C.fallax in Chrysosplenium.Voucher specimens were deposited in the Herbarium of South-Central Minzu University(HSN).
