名酒防伪包装的设计原则及应用

许多名优产品生产厂家多在其产品上应用一项或多项包装防伪技术，以达到打击假冒、保护真品的目的，但效果并不令人满意。究其原因在于，一方面企业采用的包装防伪技术本身根本不能有效遏制假冒产品，另一方面，其所采用的防伪技术的使用位置。

An investigation into the occupational protection status of clinical nursing staff exposed to anti-tumor drugs

Objective:To investigate the occupational protection status of clinical nursing staff vocationally exposed to anti-tumor drugs.Methods:A self-designed questionnaire was used to survey 180 clinical nursing staff vocationally exposed to anti-tumor drugs.Results:Recognition of the need for protection and dependent occupational protection behaviors were very poor in clinical nursing staff vocationally exposed to anti-tumor drugs.The management of the occupational protection of clinical nursing staff vocationally exposed to anti-tumor drugs was also seriously underdeveloped.Conclusion:There is deficiency in the understanding and related protection practices of clinical nursing staff vocationally exposed to anti-tumor drugs in our hospital.The protection measures currently employed in medical practice are inadequate in virtually every aspect considered.It is recommended that all clinical nursing staff should receive full occupational protection training in these matters.The training must raise nursing staff's awareness of the need for occupational protection and standardize their occupational protection behaviors to conform to "best practice" models.These "best practice" models should be quickly established and all staff made cognizant of them forthwith.In addition,where occupational protection systems are already in place,they should be improved to come into line with the new "best practice" models instigated.

Integrated Control of Tetranychus cinnabarinus by Five Kinds of Pesticides Combined with Neoseiulus cucumeris

To find the method for the integrated control of Tetranychus cinnabarinus （carmine spider mite） and delay its resistance to pesticides, the joint actions of each of five commonly pesticides （abamectin, azadirachtin, matrine, pyrethrins and imidacloprid）, and Neoseiulus cucumeris （Oudemans）, the natural enemy of cotton red spider mite, were studied. N. cucumeris was released after application of pesticides for seven days （for 0,3% azadirachtin EC） or six days （for other pesticides）. The results showed that the combined action of 1.8% abamectin EW （1：8 000） and N. cucumeris had the best control efficacy of 96.63% at 20 days after N. cucumeris releasing. The control efficacies of N. cucumeds and 0.3% azadirachtin EC （1：250） were 59.7% and 90.1% after one day and 20 days, respectively, after N. cucumeris releasing. The control efficacy of N. cucumeris and 0.5% matrine AS （1：2 000） was 82.65% at 20 days after N. cucumeris releasing. The results provide options for sustainable control of T. cinnabarinus and for the delay of pesticides resistance.

Network Pharmacology Approach to Investigate the Preventive Mechanism of Hunan Expert Group Recommended Chinese Medicine Prevention No.2 Prescription Against COVID-19

Objective To explore the possible preventive mechanism of Hunan expert group recommended Chinese medicine prescription of No.2(Pre-No.2)against coronavirus disease 2019(COVID-19)by network pharmacology method.Methods The target proteins of effective components and active compounds in Pre-No.2 were screened by searching the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP).A component-target-disease interaction network of Pre-No.2 was constructed by Cytoscape 3.7.2,gene ontology(GO)analysis,and Kyoto encyclopedia of genes and genomes(KEGG)analysis of target protein pathway by DAVID.Results A total of 163 compounds and 278 target protein targets in Pre-No.2 were collected from the TCMSP database.Kaempferol,wogonin,7-methoxy-2-methyl isoflavone,formononetin,isorhamnetin,and licochalcone A were the most frequent targets in the regulatory network.GO enrichment analysis showed that Pre-No.2 regulated response to virus,viral processes,humoral immune responses,defense responses to virus and viral entry into host cells.KEGG enrichment analysis showed that the formula regulated the NF-κB signaling pathway,B cell receptor signaling pathway,viral carcinogenesis,T cell signaling pathway and FcγR-mediated phagocytosis signaling pathway.Conclusions Pre-No.2 may play a preventive role against COVID-19 through regulation of the Toll-like signaling,T cell signaling,B cell signaling and other signaling pathways.It may regulate the immune system to protect against anti-influenza virus.

Study on the Relationship of Seismic Design Ground Motion at Different Fortification Levels in the Xinjiang Region

The seismic risk analysis results of 79 cities in Xinjiang are presented, and the bedrock peak ground accelerations under three seismic levels and their ratios are discussed. Then, the relationship between earthquake environments and the seismic risk analysis results of different exceeding probabilities are researched. The results show that minor and major earthquake motion parameters calculated from moderate earthquakes do not have a consistent probability and the ratio of bedrock peak accelerations under different exceedance probabilities are dosdy correlated with earthquake environments.

Peroxisome proliferator-activated receptorγexpression correlates with tumor angiogenesis in human hepatocellular carcinoma

Objective： To observe the association of the expression of peroxisome proliferator-activated receptor y （PPARy） with microvessel density （MVD） and vascularization mimicry （VM） in hepatocellular carcinoma （HCC） and explore their clinical significance. Methods： The expressions of PPARy and MVD and VM were tested by CD34 immunohistochemical （IHC） staining and periodic acid-Schiff （PAS） reaction in 34 cases of HCC tissues and its paired non-cancerous tissues. Their biological behaviors were analyzed and associated with the clinicopathological features. Results： PPARy was over-expressed （24/34） in HCC tissues, it was associated with tumor size （〉 5 cm, P = 0.027）, broken capsule （P = 0.014）, tendency to metastasis and recurrence （P = 0.001）. The MVD was higher （23/24） in HCC tissues than that in corresponding para-cancerous tissues （t = 18.925, P 〈 0.05）. There was a significant positive correlation between the over-expression of PPARy and high MVD （r = 0.519）. Kaplan-Meier analysis indicated that positive expression of PPARy and VM and high MVD could be used for predicating the survival rate of HCC patients （P = 0.013, 0.036 and 0.022, respectively; log-rank test）. Cox hazard model analysis showed that positive PPARy expression and high MVD were the independent prognostic factors for HCC. Conclusion： The PPARy correlated with the development of microcirculatory in HCC. PPARy is a novel prognostic indicator for evaluating of HCC.

Preventive measures of financial risks under the network environment

With the rapid development of computer networking technology, the whole world has become a ＂global village.＂ At the same time, the insistent combination of Networking technology and financial services made the traditional financial concept undergo profound changes. Financial Network is the general trend. Financial innovation has come to an Internet-based and service- oriented way of innovative rapid development stage. As the improvements of the degree of financial services network, how to effectively guard against financial risks under control network environment is an important issue we face.

Research on the Prevention Methodologies and Environmental Protection Countermeasures for Oil Pollution based on Latest Techniques from China and Abroad

In this paper, we conduct research on the prevention methodologies and environmental protection countermeasures for oil pollution based on latest techniques from China and abroad. Petroleum and petrochemical industry will also be able to have serious water pollution. Against oil pollution increasingly serious phenomenon, about how to control oil pollution has also carried on the thorough research and accumulated in the process of specific management experiences and lessons. We conduct theoretical analysis between the state-of-the-art methods of environmental protection countermeasures with examples, We firmly believe that more advances will occur in the future.

Key technology and innovation of Sutong Bridge

Sutong Bridge is a cable-stayed bridge across Yangtze River with the main span of 1 088 m. This article outlines technical challenges,key technology and innovation in the design and construction such as scour protection,lowering steel cofferdam,construction platform establishment,construction and control of pylons,fabrication and damping of long cables,erection and control of steel box girders.

A case study of the role of climate, humans, and ecological setting in Holocene fire history of northwestern Europe

We present the major results from studies of fire history over the last 11000 years(Holocene) in southern Sweden, on the basis of palaeoecological analyses of peat sequences from three small peat bogs. The main objective is to emphasize the value of multiple, continuous sedimentary records of macroscopic charcoal(macro-C) for the reconstruction of local to regional past changes in fire regimes, the importance of multi-proxy studies, and the advantage of model-based estimates of plant cover from pollen data to assess the role of tree composition and human impact in fire history. The chronologies at the three study sites are based on a large number of 14 C dates from terrestrial plant remains and age-depth models are achieved using Bayesian statistics. Fire history is inferred from continuous records of macro-C and microscopic charcoal counts on pollen slides. The Landscape Reconstruction Algorithm(LRA) for pollen-based quantitative reconstruction of local vegetation cover is applied on the three pollen records for plant cover reconstruction over the entire Holocene. The results are as follows:(1) the long-term trends in fire regimes are similar between sites, i.e., frequent fires during the early Holocene until ca. 9 ka BP, low fire frequency during the mid-Holocene, and higher fire frequency from ca. 2.5 ka BP;(2) this broad trend agrees with the overall fire history of northwestern and western Europe north of the Mediterranean area, and is due to climate forcing in the early and mid-Holocene, and to anthropogenic land-use in the late Holocene;(3) the LRA estimates of plant cover at the three sites demonstrate that the relative abundance of pine played a primordial role in the early and mid-Holocene fire history; and(4) the between-site differences in the charcoal records and inferred fire history are due to local factors(i.e., relative abundance of pine, geomorphological setting, and anthropogenic land-use) and taphonomy of charcoal deposition in the small peat bogs. It is shown that continuous macro-C records are most useful to disentangle local from regional-subcontinental fire history, and climate-induced from human-induced fire regimes, and that pollen-based LRA estimates of local plant cover are more adequate than pollen percentages for the assessment of the role of plant composition on fire history.