勿忘“验根”

在今年某地初中数学考试中有这样一道题: 若关于x的方程2x+a/x-2=-1的解为正数,则a的取值范围是__.

Clinical experimental study of Arnebia root oil promoting histological change and up-regulating bFGF expression in the wound

Objective: To explore the molecular biological mechanism of Arnebia root oil promoting wound surface healing by observing histological change and bFGF expression in wound surface tissue as well as wound surface healing rate. Methods: Raw surface in patients were randomly divided into 2 groups. Experimental group was treated by Arnebia root oil and control group was treated by petrolatum gauze, then the tissular structure of raw surface was observed by histology, histochemistry. electron microscope and raw surface healing rates was compared either. bFGF expression in wound surface tissue was also evaluated by Western-blot. Results: Raw surface healing rate of experimental group and control group had obvious difference(P<0. 05). Raw surface of experimental group had more fibroblast, collagen and blood capillary. bFGF was expressed in both groups, and the level of bFGF expression in experimental group was higher than that in control group in every period. There were significant differences between 2 groups in gray-density value ( P<0. 05). Being as an internal control, no significant change was found for β-actin expression, although it occured in various phases. Conclusion: Arnebia root oil plays an important regulative role in the course of healing of wound and it can promote skin raw surface repair and accelerate wound surface healing, which are caused by enhancing bFGF in the wound tissue.

Validation and intercomparison of HY-2A/MetOp-A/Oceansat-2 scatterometer wind products

Sea surface winds are of great significance in scientific research. In the last few years,three series of scatterometers were launched to measure these winds,including the Advanced Scatterometer(ASCAT) aboard Meteorological Operational Satellite A(Met Op-A) and Met Op-B,Oceansat-2 Scatterometer(OSCAT),and HY-2A Scatterometer(HY-2A SCAT). Based on buoy wind data,validation and intercomparison of these scatterometers were performed. Scatterometer-derived wind and buoy wind data were collected only if the spatial difference was less than 0.1 degree and temporal difference less than 5 min. After discarding wind direction data outside five times the standard deviation,ASCAT wind products showed high accuracy in both wind speed and direction,with root-mean-square error(RMSE) 0.86 m/s and 17.97 degrees,respectively. HY-2A SCAT nearly meets the mission requirement,with RMSE for wind speed 1.23 m/s and 22.85 degrees for wind direction. OSCAT had poor performance when compared with the others. RMSE for wind speed was 1.54 m/s and 39.86 degrees for wind direction,which greatly exceeds the mission requirement of 20 degrees. In addition,the RMSE for wind direction shows a high-low pattern on buoy wind speed. However,a wind speed range from 14 to 15 m/s was found to be abnormal,and the reason remains unclear. There was no systematic dependency of both wind speed and direction residuals on buoy wind speed and cross-track location of the wind vector cells across the entire range. No seasonal variation was found for any scatterometer.

Dual therapy for third-line Helicobacter pylori eradication and urea breath test prediction

We evaluated the efficacy and tolerability of a dual therapy with rabeprazole and amoxicillin (AMX) as an empiric third-line rescue therapy. In patients with failure of first-line treatment with a proton pump inhibitor (PPI)- AMX-clarithromycin regimen and second-line treatment with the PPI-AMX-metronidazole regimen, a third-line eradication regimen with rabeprazole (10 mg q.i.d.) and AMX (500 mg q.i.d.) was prescribed for 2 wk. Eradication was confirmed by the results of the 13C-urea breath test (UBT) at 12 wk after the therapy. A total of 46 patients were included; however, two were lost to followup. The eradication rates as determined by per-protocol and intention-to-treat analyses were 65.9% and 63.0%,respectively. The pretreatment UBT results in the subjects showing eradication failure; those patients showing successful eradication comprised 32.9 ± 28.8 permil and 14.8 ± 12.8 permil, respectively. The pretreatment UBT results in the subjects with eradication failure were significantly higher than those in the patients with successful eradication (P = 0.019). A low pretreatment UBT result (≤ 28.5 permil) predicted the success of the eradication therapy with a positive predictive value of 81.3% and a sensitivity of 89.7%. Adverse effects were reported in 18.2% of the patients, mainly diarrhea and stomatitis. Dual therapy with rabeprazole and AMX appears to serve as a potential empirical third-line strategy for patients with low values on pretreatment UBT.

Domestication Test of Halopegia azurea （Karl Moritz Schumann） （Marantaceae）： Preliminary Study on the Rhizome Cuttings

In order to domesticate H. azurea （Halopegia azurea）, acclimatization of rhizome＇s cuttings and young shoots in farms was tested at Nkol Evodo village from February 2012 to June 2012. The best substrate for propagation was assessed： （0） wetland; （1） sand/wetland; （2） sawdust/wetland; （3） sand/sawdust/wetland. Young shoots＇ growth was observed in situ for 8 weeks. A significant difference （P 〈 0.05） was observed in the appearance of young shoots and leaves in nursery. The highest average number of young shoots and leaves （0.62 ± 0.09） was found in substrates 0 and 1, the lowest （0.31 ± 0.08） in substrate 3. Substrate 3 showed the lowest number of young leaves （0.41 ± 0.16） and substrate 2 the highest （0.97 ±0.24）. A significant difference in the mortality rate of cuttings （P 〈 0.05） was observed： 68.75% and 53.12% in substrates 2 and 3, respectively. On farm, new leaves and young shoots＇ appearance showed a highly significant difference. Plants growing in substrates 2 and 3 showed the highest number of leaves. New shoots developed only in plants growing in substrates 0 and 1. These results suggest that it is possible to domesticate H. azurea for leaves＇ production in quantity and quality, and open up better opportunities for its cultivation.

Studies on the Allelopathic Potential of Corn （Zea mays L.） Aqueous Extracts and Root Exudates

This investigation was carried out at Faculty of Agriculture and Forestry-University of Duhok/Kurdistan-Iraq. Three experiments were included in this investigation： （1） First experiment was a bioassay related to the germination performance, shoot and root development of corn （Zea mays L.） and peanut （Arachishypogaea） at two concentrations of root （3% and 1.5%） and shoot （12% and 6%） aqueous extracts of corn medium; （2） The second experiment dedicated to the intercropping of corn and peanut at four treatments; （3） While the third experiment involved the effect of peanut root exudation on growth of corn. Experiment results revealed that corn shoot and root water extracts highly inhibited seed germination of both corn and peanut, the inhibitory of shoot extract was more than root aqueous extract. While its effect on the seedling growth was vice versa as compared with control treatment, there was an increase in root and shoot length of both corn and peanut when grown in corn aqueous extracts. Intercropping experiment results has stimulated most traits of peanut under studying. Also for corn, there was apparent and significant increase in all characteristics as compared with control. It was further confirmed from the results of peanut root exudates that had all studied characters of corn were stimulated than the control treatment.

Phytoremediation of PAH-Contaminated Sediments by Potamogeton Crispus L. with Four Plant Densities

In order to investigate the effect of plant density ofPotamogeton crispus L. on the remediation of sedi- ments contaminated by polycyclic aromatic hydrocarbons, a 54-day experiment with four plant densities （642, 1 604, 2 567 and 3 530 plants/m^2） was conducted. The results showed higher plant density with slower plant growth rate. Surface area per plant was the most sensitive root parameter to plant density. At the end of the 54-day experi- ment, planting P. crispus enhanced the dissipation ratios of phenanthrene and pyrene in sediments by 6.5%-26,2% and 0.95%-13.6%, respectively. The dissipation increment increased with increasing plant density. Plant uptake accounted for only a small portion of the dissipation increments. Furthermore, P. crispus could evidently improve sediment redox potentials, and strong positive correlations between root surface area and the redox potential as well as between the redox potentials and the dissipation ratios of phenanthrene and pyrene were obtained, indicating that the oxygen released by the roots ofP. crispus might be the main mechanism by which P. crispus enhanced the dis- sipation of PAHs in sediments.

The weak form market efficiency investigation of American, European and Asian stock markets

This paper investigates the empirical validity of the Weak Form Efficient Market Hypothesis for American, European and Asian stock markets. Random Walk Hypothesis is used to prove weak form efficiency in American, European and Asian stock indices. ADF and PP Unit Root Tests have been used to test unit root in time series of daily data of American, European and Asian stock indices. Results show that sample of stock markets are weak-form efficient in terms of the Random Walk Hypothesis.

Vector Autoregressive （VAR） Modeling and Projection of DSE

In this paper, vector autoregressive （VAR） models have been recognized for the selected indicators of Dhaka stock exchange （DSE）. Bangladesh uses the micro economic variables, such as stock trade, invested stock capital, stock volume, current market value, and DSE general indexes which have the direct impact on DSE prices. The data were collected for the period from June 2004 to July 2013 as the basis on daily scale. But to get the maximum explorative information and reduction of volatility, the data have been transformed to the monthly scale. The outliers and extreme values of the study variables are detected through box and whisker plot. To detect the unit root property of the study variables, various unit root tests have been applied. The forecast performance of the different VAR models is compared to have the minimum residual. Moreover, the dynamics of this financial market is analyzed through Granger causality and impulse response analysis.

Dye tracer infiltration technique to investigate macropore flow paths in Maka Mountain, Yunnan Province, China

In order to investigate the differences of macropores vertical distribution under different surface plants, and to assess the influences of root systems, organic matter and texture on macropore flow paths, two dye tracer infiltration experiments were performed in slopes under two different plants(Campylotropis polyantha(Franch.) Schindl vs. Cynodon dactylon(Linn.) Pers). Dye tracer infiltration experiments with field observations and measurements of soil properties were combined. Results show that the discrepancy in macropores distribution between two slopes under different plants is significant. Root systems have significant effects on macropore flow paths distribution and the effect become more pronounced as the diameter of roots become larger. Organic matter and stone are important factors to affect macropores distribution. Root-soil interface, inter-aggregate macropore and stone-soil interface are important macropore flow paths in well vegetated slopes.

Is There Hysteresis in Unemployment in OECD Countries？ Evidence From Panel Unit Root Test With Structural Breaks

This study tests the hysteresis hypothesis of unemployment in fifteen OECD countries by using panel unit root tests which allow for structural breaks. We apply annual unemployment rates covering 1985-2008 periods. We test whether unemployment rates are stationary by using second generation tests which allow cross section dependency among series and panel unit root test based on structural break advanced by Carrion-i-Silvestre, Barrio-Castro and Lopez-Bazo （2005）. We find series as a stationary process with structural breaks according to Carrion-i Silvestre et al. （2005） test, while we find series as unit root process with second generation panel unit root test. According to the Carrion-i Silvestre et al. （2005） test, we find the evidence of absence of hysteresis in analyzed countries. As a result, temporary shocks have temporary effects on unemployment instead of permanent effect. Structural factors can affect the natural rate of unemployment and, therefore, unemployment would be stationary around a process that is subject to structural breaks. So, there still exists a unique natural rate of unemployment to which the economy eventually will converge.

Islamic Banking and Economic Growth： Evidence From Asia

This paper investigates the short- and long-run causality relationship between Islamic banking and the economic growth. The main goal of this paper is to examine the relationship between the economic growth and Islamic banking. The dataset used covers the Asia countries over the period of 1980-2009. The unit root test Im, Pesaran, and Shin （IPS） （2003） confirms that all of the variables that the authors use in the equation below are stationary. The empirical result of the Granger causality test shows a bidirectional relationship between Islamic banking and the economic growth and also a bidirectional relationship between the economic growth and export.

The Calendar Anomalies of Stock Return in Thailand

This paper aims to examine the existence of calendar anomalies including month-of-year effect, turn-of-month effect, and weekend effect in Thai stock market. The stock return is computed from SET index during 1988 to 2009 and the SET50 index gathered since it was created in 1995. The unit root test is performed to ensure that the stock return series have no unit root. The multiple regression techniques using dummy variables are employed to test the difference of the return during each calendar anomalies period. If the regression model suffers from conditional heteroskedasticity, the GARCH （1, 1） model will be used instead of normal ordinary least square regression. It was found that the calendar anomalies exist in Thai stock market. The return is abnormally high during December and January, which can be addressed to be the turn-of-year effect. The return during the turn-of-month period, which can be defined as the last trading day and the first four trading days of the following months, is also abnormally high. Finally, the return is also abnormally high on Fridays but abnormally low on Mondays, which is addressed as weekend effect. This may create the opportunity to make above-average profit to investors exploiting these calendar anomalies. Although these calendar anomalies may be difficult to be exploited in practice because of transaction costs and ability to replicate the stock index, the existing evidence of calendar anomalies can help investors as the clue for the timing of investment.

The Impacts of External Debt on Economic Growth in Transition Economies

The 1989 and following years were the periods in which many important economic and political tumovers took place in the world. That was the time when Berlin Wall fell down with scattering the Eastern block and many politically independent states came into being, at the same time, ongoing about 70 years socialist system also started to change into liberal system. The constituted 27 states in 1991 were tended to liberal economic system instead of socialist economy, and these states were called as transition economies. In this study, the relationship between indebtedness and growth rate of transition countries were analyzed by panel autoregressive distributed lag model （ARDL）. Before panel ARDL application, stationary properties of the variables have been checked with first and second generation unit root test. For the second generation unit root tests, CADF tests have been used. Also cross section dependency has been examined by LM tests.

Cohesive Strength and Seismogenic Stress Pattern along the Active Basement Faults of the Precordillera-Sierras Pampeanas Ranges,Western Argentina:An Experimental Analysis by Means of Numerical Model

A two-dimensional finite element method （FEM） model that incorporates faults, elastic rock physical properties, topographical load due to gravity and far-field plate velocity boundary conditions was used to recognize the seismogenic stress state along the fold-and-thrust belt of the Precordillera-Sierras Pampeanas ranges of western Argentina. A plane strain model with nine experiments was presented here to examine the fault strength with two major rock phyical properties： cohesion and angle of internal friction. Mohr-Coulomb failure criterion with bulk rock properties were applied to analyse faults. The stress field at any point of the model was assumed to be comprised of gravitational and tectonic components. The analysis was focused to recognize the seismogenic shear strain concentrated in the internal-cristaline domain of the orogene shown by the modeling. Modeling results are presented in terms of four parameters, i. e., （i） distributions, orientations, and magnitudes of principal stresses （σ1 and σ3）, （ii） displacement vector1 （iii） strain distribution, and （iv） maximum shear stress （τmax） contour line within the model. The simulation results show that the compressive stress is distributed in and around the fault systems. The overall orientation of of σ1 is in horizontal directions, although reorientations do occur within some stress weaker parts, especially subsequent to the faults. A large-scale shear stress is accumulating along the active faults of Tapias-Villicum Fault （TVF）, Salinas-Berros Fault （SBF）, Ampacama-Niquizanga Fault （ANF） and Las Charas Fault （CF）, which could act as local stress and strain modulators to localize the earthquakesoccurrence.

Mechanistic Model for Predicting NO_3-N Uptake by Plants and Its Verification

Some mechanistic models have been proposed to predict the No3- concentrations in the soil solution at root surface and the NO3-N uptake by plants, but all these relatively effective non-steady state models have not yet been verified by any soil culture experiment. In the present study, a mathematical model based on the nutrient transport to the roots, root length and root uptake kinetics as well as taking account of the inter-root competition was used for calculation, and soil culture experiments with rice, wheat and rape plants grown on alkali, neutral and acid soils in rhizoboxes with nylon screen as a isolator were carried out to evaluate the prediction ability of the model through comparing the measured NO3-concentrations at root surface and N uptake with the calculated values. Whether the inter-root competition for nutrients was accounted for in the model was of less importance to the calculated N uptake but could induce significant changes in the relative concentrations of NO3- at root surface. For the three soils and crops, the measured NO3-N uptake agreed well with the calculated one, and the calculated relative concentrations at root surface were approximate to the measured values. But an appropriate rectification for some conditions is necessary when the plant uptake parameter obtained in solution culture experiment is applied to soil culture. In contrast with the present non-steady state model, the predicted relative concentrations, which show an accumulation, by the Phillips' steady-state model were distinct from the measured values which show a depletion, indicating that the present model has a better prediction ability than the steady-state model.

Validation of a method to predict hammer speed from cable force

Purpose： The purpose of this study was to develop and validate a method that would facilitate immediate feedback on linear hammer speed during training. Methods： Three-dimensional hammer head positional data were measured and used to calculate linear speed （calculated speed） and cable force. These data were used to develop two linear regression models （shifted and non-shifted） that would allow prediction of hammer speed from measured cable force data （predicted speed）. The accuracy of the two models was assessed by comparing the predicted and calculated speeds. Averages of the coefficient of multiple correlation （CMC） and the root mean square （RMS） of the difference between the predicted and calculated speeds for each throw of each participant were used to assess the level of accuracy of the predicted speeds. Results： Both regression models had high CMC values （0.96 and 0.97） and relatively low RMS values （1.27 m/s and 1.05 m/s） for the non-shifted and shifted models, respectively. In addition, the average percentage differences between the predicted and calculated speeds were 6.6% and 4.7% for the non-shifted and shifted models, respectively. The RMS differences between release speeds attained via the two regression models and those attained via three-dimensional positional data were also computed. The RMS differences between the predicted and calculated release speeds were 0.69 m/s and 0.46 m/s for the non-shifted and shifted models, respectively. Conclusion： This study successfully derived and validated a method that allows prediction of linear hammer speed from directly measured cable force data. Two linear regression models were developed and it was found that either model would be capable of predicting accurate speeds. However, data predicted using the shifted regression model were more accurate.

Gene expression profiling and endothelin in acute experimental pancreatitis

AIM:To analyze gene expression profiles in an experimental pancreatitis and provide functional reversal of hypersensitivity with candidate gene endothelin-1 antagonists.METHODS:Dibutyltin dichloride(DBTC) is a chemical used as a polyvinyl carbonate stabilizer/catalyzer,biocide in agriculture,antifouling agent in paint and fabric.DBTC induces an acute pancreatitis flare through generation of reactive oxygen species.Lewis-inbred rats received a single i.v.injection with either DBTC or vehicle.Spinal cord and dorsal root ganglia(DRG) were taken at the peak of inflammation and processed for transcriptional profiling with a cDNA microarray biased for rat brain-specific genes.In a second study,groups of animals with DBTC-induced pancreatitis were treated with endothelin(ET) receptor antagonists [ET-A(BQ123) and ET-B BQ788)].Spontaneous pain related mechanical and thermal hypersensitivity were measured.Immunohistochemical analysis was performed using anti-ET-A and ET-B antibodies on sections from pancreatic tissues and DRG of the T10-12 spinal segments.RESULTS:Animals developed acute pancreatic inflammation persisting 7-10 d as confirmed by pathological studies(edema in parenchyma,loss of pancreatic architecture and islets,infiltration of inflammatory cells,neutrophil and mononuclear cells,degeneration,vacuolization and necrosis of acinar cells) and the painrelated behaviors(cutaneous secondary mechanical and thermal hypersensitivity).Gene expression profile was different in the spinal cord from animals with pancreatitis compared to the vehicle control group.Over 260 up-regulated and 60 down-regulated unique genes could be classified into 8 functional gene families:circulatory/acute phase/immunomodulatory;extracellular matrix;structural;channel/receptor/transporter;signaling transduction;transcription/translation-related;antioxidants/chaperones/heat shock;pancreatic and other enzymes.ET-1 was among the 52 candidate genes upregulated greater than 2-fold in animals with pancreatic inflammation and visceral pain-related behavior.Treatments with the ET-A(BQ123) and ET-B(BQ-788) antagonists revealed significant protection against inflammatory pain related mechanical and thermal hypersensitivity behaviors in animals with pancreatitis(P < 0.05).Open field spontaneous behavioral activity(at baseline,day 6 and 30 min after drug treatments(BQ123,BQ788) showed overall stable activity levels indicating that the drugs produced no undesirable effects on normal exploratory behaviors,except for a trend toward reduction of the active time and increase in resting time at the highest dose(300 μmol/L).Immunocytochemical localization revealed that expression of ET-A and ET-B receptors increased in DRG from animals with pancreatitis.Endothelin receptor localization was combined in dual staining with neuronal marker NeuN,and glia marker,glial fibrillary acidic protein.ET-A was expressed in the cell bodies and occasional nuclei of DRG neurons in na ve animals.However,phenotypic expression of ET-A receptor was greatly increased in neurons of all sizes in animals with pancreatitis.Similarly,ET-B receptor was localized in neurons and in the satellite glia,as well as in the Schwann cell glial myelin sheaths surrounding the axons passing through the DRG.CONCLUSION:Endothelin-receptor antagonists protect against inflammatory pain responses without interfering with normal exploratory behaviors.Candidate genes can serve as future biomarkers for diagnosis and/or targeted gene therapy.

Forms of nitrogen uptake,translocation,and transfer via arbuscular mycorrhizal fungi:A review

Arbuscular mycorrhizal （AM） fungi are obligate symbionts that colonize the roots of more than 80% of land plants. Experi- ments on the relationship between the host plant and AM in soil or in sterile root-organ culture have provided clear evidence that the extraradical mycelia of AM fungi uptake various forms of nitrogen （N） and transport the assimilated N to the roots of the host plant. However, the uptake mechanisms of various forms of N and its translocation and transfer from the fungus to the host are virtually unknown. Therefore, there is a dearth of integrated models describing the movement of N through the AM fungal hyphae. Recent studies examined Ri T-DNA-transformed carrot roots colonized with AM fungi in ~SN tracer experi- ments. In these experiments, the activities of key enzymes were determined, and expressions of genes related to N assimilation and translocation pathways were quantified. This review summarizes and discusses the results of recent research on the forms of N uptake, transport, degradation, and transfer to the roots of the host plant and the underlying mechanisms, as well as re- search on the forms of N and carbon used by germinating spores and their effects on amino acid metabolism. Finally, a path- way model summarizing the entire mechanism of N metabolism in AM fungi is outlined.