The first total synthesis of (±)-13-hydroxy-8 (14)-abietene was accomplished in 20.1% yield via a strategy of AC→ABC, in which the reduction of compound 5 with Li/NH3 gave the key intermediate 6 and the title co...The first total synthesis of (±)-13-hydroxy-8 (14)-abietene was accomplished in 20.1% yield via a strategy of AC→ABC, in which the reduction of compound 5 with Li/NH3 gave the key intermediate 6 and the title compound was then obtained by the reaction of compound 6 with Grignard reagent.展开更多
文摘The first total synthesis of (±)-13-hydroxy-8 (14)-abietene was accomplished in 20.1% yield via a strategy of AC→ABC, in which the reduction of compound 5 with Li/NH3 gave the key intermediate 6 and the title compound was then obtained by the reaction of compound 6 with Grignard reagent.
