Challenges and Suggestions of Ethical Review on Clinical Research Involving Brain-Computer Interfaces

Brain-computer interface(BCI)technology is rapidly advancing in medical research and application.As an emerging biomedical engineering technology,it has garnered significant attention in the clinical research of brain disease diagnosis and treatment,neurological rehabilitation,and mental health.However,BCI also raises several challenges and ethical concerns in clinical research.In this article,the authors investigate and discuss three aspects of BCI in medicine and healthcare:the state of international ethical governance,multidimensional ethical challenges pertaining to BCI in clinical research,and suggestive concerns for ethical review.Despite the great potential of frontier BCI research and development in the field of medical care,the ethical challenges induced by itself and the complexities of clinical research and brain function have put forward new special fields for ethics in BCI.To ensure"responsible innovation"in BCI research in healthcare and medicine,the creation of an ethical global governance framework and system,along with special guidelines for cutting-edge BCI research in medicine,is suggested.

Perspectives from a publishing ethics and research integrity team for required improvements

It is imperative that all stakeholders within the research ecosystem take responsibility to improve research integrity and reliability of published research.Based on the unique experiences of a specialist publishing ethics and research integrity team within a major publisher,this article provides insights into the observed trends of misconduct and how those have evolved over time,and addresses key actions needed to improve the interface between researchers,funders,institutions and publishers to collectively improve research integrity on a global scale.

Ethical framework for artificial intelligence in healthcare research:A path to integrity

The integration of Artificial Intelligence(AI)into healthcare research promises unprecedented advancements in medical diagnostics,treatment personalization,and patient care management.However,these innovations also bring forth significant ethical challenges that must be addressed to maintain public trust,ensure patient safety,and uphold data integrity.This article sets out to introduce a detailed framework designed to steer governance and offer a systematic method for assuring that AI applications in healthcare research are developed and executed with integrity and adherence to medical research ethics.

Applied Ethics and Modem Enterprises One Viewpoint

Business ethics has been growing from a philosophy discipline to an applied science. That explains its significance for more efficient functioning of various systems in business world. For that reason, organized societies with developed economies invest in empiric, theoretic, and theoretic-empiric investigations of various sectors and applied dimensions of business ethics. Its epistemological sense reflects to increasing productivity, more successful establishing of the system of hierarchy within an enterprise, appropriate formulating the strategy of management, improving the market reputation, increasing profitability, and strengthening social responsibility. The complexity of modem and successful business is based on a series of social factors which spread in the arch from anthropological, socially-psychological, and cultural characteristics of a human being, to quality characteristics of the global society. That is why the scientific information available to business ethics is synthesized from various scientific perspectives. This paradigm is a starting point of this project which is about the above subject. Its cognitive aim is presented through the description, classification, and explanation of the influence of business ethics to successful functioning of every kind of business institution. As a theoretic investigation which grows from verified scientific information and their critical analysis, it relies on standard, general scientific, basic special and general methods which are characteristic to the applied scientific disciplines. Business ethics has clearly established two key cognitive bases of its investigations： 1） personal value attitude; and 2） interests of a company, groups, and individuals in them. This project is only a small contribution to explaining elementary functions of this applied ethics in business world.

Meru University of Science and Technology Research Ethics Review System: A SWOT Analysis

The objectives of this article are as follows: 1) to propose a university research ethics system framework, 2) to provide a brief anatomy of the Meru University of Science and Technology (MUST) Institutional Research Ethics Review Committee (MIRERC), 3) to perform a SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis of MIRERC, and 4) to make recommendations for improving its performance. The 13-member multi-disciplinary MIRERC was established in April 2017 to provide effective ethical oversight of research undertaken by the University’s scholarly community. Strengths of the MUST research ethics review system include a functional MIRERC, a pertinent national law and ethical guidelines, an Innovation and Enterprise Centre that could house a dedicated MIRERC Secretariat, and a supportive University Management Board. The weaknesses include lack of graduate schools to assure scientific rigor of proposals before submission to the MIRERC, lack of research ethics training in most school’s curricula, absence of a dedicated MIRERC Secretariat, undergraduate research proposals being not ethically reviewed, dearth of faculty trained in research ethics, and lack of an operating budget for MIRERC work. The opportunities include existence of about 22 accredited Institutional Research Ethics Review Committees (IRERC) in Kenya, existence of international standards and operational guidance for ethics review, availability of guidelines and codes of best ethical practices in research, existence of a free automated platform called Research for Health Innovation Organizer (RHInnO) Ethics for managing the ethics review process, and availability of external resources for strengthening IRERCs. In order to improve the performance and sustainability of the MUST research ethics system, there is need to include research ethics training in all undergraduate and post-graduate curricula, create a dynamic database of potential research ethics reviewers, allocate a percentage of the annual MUST research budget for MIRERC operations, charge a graduated fee for proposal ethics review, require all students’ and faculties’ internal and external research proposals be cleared by the MIRERC, and use the RHInnO Ethics platform to manage the ethics review process.

Ethical Criteria in Research in Music Education in Brazil

The growth of research in Music Education in Brazil,together with the advancement of ethical care in research,originated this research that aimed to investigate aspects related to ethical care in research in Music Education in Brazil,based on Resolution No.510/2016,which deals with ethics in research with human beings.Data were collected via Internet,in the journal of the Brazilian Association of Music Education(known by the acronym ABEM),with a time frame from 2016 to 2022.As a result,five papers were found.It is understood,in this sense,that there is room for the growth of investigations in Music Education that deal with research ethics.Despite the advances in legislation regarding research ethics,as well as the need for investigations in Music Education to also consider these issues in their data collection and analysis,the theme has still been little considered in methodological procedures.

The ethics of exercise in eating disorders:Can an ethical principles approach guide the next generation of research and clinical practice?

1.Introduction Eating disorders(ED)are the most common psychiatric disorders afflicting young women^1 and contribute to great detriments in psychological,social,and physical health.^(2,3)Unfortunately,ED treatments tend to be long lasting,intensive,and expensive.~4Additionally,individuals with ED seeking treatment use healthcare services more frequently than non-ED individu-

AP assembled on ultrafine aluminum particle and its application to NEPE propellant

Coating modification is an important way to enhance the reactivity of aluminum powder.In this paper,ammonium perchlorate and aluminum powder were assembled into energetic microunits by liquid deposition method.Spherical particles with AP as shell and ultrafine aluminum powder as the core(Al@AP)were gained.The micromorphology results show that the coated particles are about 5μm,and the coating layer is evenly distributed on the outer surface of aluminum powder,indicating a complete coating.The energetic microunits were implanted into the nitrate ester plasticizing adhesive system(NEPE)as solid phase fillers.The effect of filler on the rheological properties,safety,mechanical properties,thermal reaction and energy properties of the system was analyzed by comparing with the raw aluminum filler.The test results show that the rheological properties,mechanical properties and pressure index of NEPE containing system Al@AP meets the requirements of solid propellant charging.Compared with Al based propellant,the mechanical sensitivity and thermal sensitivity are decreased,the safety is better,and the explosion heat of the propellant is increased by 7.8%.The engine test shows that the specific impulse is increased by 1.2 s.Al@AP can improve the energy output and safety of NEPE propellant,and has potential application prospects in high-energy propellants.

Research funding and citations in papers of Nobel Laureates in Physics, Chemistry and Medicine, 2019-2020

Purpose:The goal of this study is a comparative analysis of the relation between funding(a main driver for scientific research)and citations in papers of Nobel Laureates in physics,chemistry and medicine over 2019-2020 and the same relation in these research fields as a whole.Design/methodology/approach:This study utilizes a power law model to explore the relationship between research funding and citations of related papers.The study here analyzes 3,539 recorded documents by Nobel Laureates in physics,chemistry and medicine and a broader dataset of 183,016 documents related to the fields of physics,medicine,and chemistry recorded in the Web of Science database.Findings:Results reveal that in chemistry and medicine,funded researches published in papers of Nobel Laureates have higher citations than unfunded studies published in articles;vice versa high citations of Nobel Laureates in physics are for unfunded studies published in papers.Instead,when overall data of publications and citations in physics,chemistry and medicine are analyzed,all papers based on funded researches show higher citations than unfunded ones.Originality/value:Results clarify the driving role of research funding for science diffusion that are systematized in general properties:a)articles concerning funded researches receive more citations than(un)funded studies published in papers of physics,chemistry and medicine sciences,generating a high Matthew effect(a higher growth of citations with the increase in the number of papers);b)research funding increases the citations of articles in fields oriented to applied research(e.g.,chemistry and medicine)more than fields oriented towards basic research(e.g.,physics).Practical implications:The results here explain some characteristics of scientific development and diffusion,highlighting the critical role of research funding in fostering citations and the expansion of scientific knowledge.This finding can support decision-making of policymakers and R&D managers to improve the effectiveness in allocating financial resources in science policies to generate a higher positive scientific and societal impact.

PROGRESS IN “APPLIED RESEARCH ON DROUGHT & DESERTIFICATION”——A fruitful cooperative program between China and the World Laboratory

World Laboratory (WL) is an international organ financed by the Italian Ministry of Foreign Affairs and its operation is exclusively for the Third World countries, where basic research projects are carried out and research results are applied to the benefit of the local areas and the world as a whole. The Project of"Applied Research on Drought &

Biobanks and biomarkers:Their current and future role in biomedical research

The importance and utility of biobanks has increased exponentially since their inception and creation.Initially used as part of translational research,they now contribute over 40%of data for all cancer research papers in the United States of America and play a crucial role in all aspects of healthcare.Multiple classification systems exist but a simplified approach is to either classify as population-based or disease-oriented entities.Whilst historically publicly funded institutions,there has been a significant increase in industry funded entities across the world which has changed the dynamic of biobanks offering new possibilities but also new challenges.Biobanks face legal questions over data sharing and intellectual property as well as ethical and sustainability questions particularly as the world attempts to move to a low-carbon economy.International collaboration is required to address some of these challenges but this in itself is fraught with complexity and difficulty.This review will examine the current utility of biobanks in the modern healthcare setting as well as the current and future challenges these vital institutions face.

Ethics and Its Relations With Education and Research

Brazilian studies in （Critical） Applied Linguistics＇ field have being carried out focusing on ethics. They focused on the relation between ethics and two main contexts： education and research. This paper aims at discussing what ethical procedures were taken in international studies. The data were collected at ERIC （Educational Resources Information Centre） database during the first semester of 2016. As analytical categories, we used the ethical procedures established by Brazilian Applied Linguists. The contribution is addressed to both BAL and International Applied Linguists once it offers an overview about a specific topic of research （viz., ethics）. As results, we observed that most of the topics presented by the Brazilian applied linguists were also covered by the research analyses. However, the social relevance was not reported properly by the data and that may be improved.

A Study on the Application of Evidence-Based Nursing in The Care of Patients with Severe Acute Pancreatitis

Objective: To explore the application research of evidence-based nursing in the care of patients with severe acute pancreatitis. Methods: This study focuses on evidence-based nursing care of severe acute pancreatitis. Patients with severe acute pancreatitis who received treatment in our hospital were selected, from which 80 cases were chosen for detailed analysis. The patients were randomly grouped into a control group (conventional nursing care) and a study group (evidence-based nursing care), with 40 patients each. Relevant research data were recorded during the nursing process, analyzed, and used as research indicators. Results: The hospitalization time and morbidity and mortality rate of the research group were shorter than those of the control group, and the recovery rate was higher than that of the control group (P < 0.05). Patient satisfaction with nursing care in the observation group was higher than in the control group (P < 0.05). Conclusion: For patients with severe acute pancreatitis, the use of evidence-based nursing methods effectively reduced the patient’s mortality rate, improved its curative effect, and also shortened the patient’s hospitalization time.

The Strength of Training and Applied Research on Specialized Sociology to Contribute to the Social Science Development(Case Study in the Southern Region of Vietnam)

With the common trend of integration and accelerated industrialization-modernization,especially in the context of the current Industrial Revolution 4.0,the South is one of the areas where there are situations and requirements especially for training and research in social sciences in general,sociology in particular.Because,the issue is not only to contribute to the early recovery of the―human resource valley‖(specializing in the South West),facilitating the rapid development of human resources for―investment policy‖and early implementation of the―zoning,planning‖but also by many other economic,social,and cultural issues of the whole region…All have been asked to promote the training and applied research in sociology,especially in specialized sociology to contribute to the linking and promoting the active role of the social sciences with strategic issues and strategies related to the practical development of this land both in the immediate future and in the long run.

Practice on Capability Accreditation Program(CAP)of Ethics Review System for Chinese Medicine Research

Capability Accreditation Program(CAP) of Ethics Review System for Chinese Medicine Research of World Federation of Chinese Medicine Societies(WFCMS) is the first certification project in the field of Chinese medicine research on ethics review. Based on the Requirements for Ethical Review of Biomedical Research Involving Human, ethical review system for Chinese medicine research was established and standardized from 4 aspects, such as organization, ethics committee, office of the ethics committee, and researchers. The period of CAP certification is three years, which include certification application and acceptance, initial certification(document review, on-site audit), certification decision, and supervision audit. The implementation of the CAP certification is of great importance for upgrading the research on ethics review system of Chinese medicine, which promotes the development of the research on ethics review system in China and the continuous improvement of the ability of the Chinese medicine research on ethics review.

Researches on the teaching based on the applied linguistics

Along with the development of the times and the innovation of the society, the history and cultures are also constantly inherited under the strike of the flow of the tide over the years, forming the centuries-old cultures. Of course, the heritage of any culture needs a carrier, and the history and culture is no exception. Language itself is a kind of tool for the information exchange, and the communication process of the language is also accompanied by the substitution of the culture. So it can be said it is not only the category of the information exchange, but should be expanded to the cultural heritage. With the continuous changes and development of the society, people focused more on the application in the learning of the language, so as to highlight the characteristics of different cultures through the applications in different aspects.

Theory-laden model of ethical applications and ethics of euthanasia

The primary aim of this paper is to critically evaluate the deductive model of ethical applications,which is based on normative ethical theories like deontology and consequentialism,and to show why a number of models have failed to furnish appropriate resolutions to practical moral problems.Here,for the deductive model,I want to call it a“Linear Mechanical Model”because the basic assumption of this model is that if a normative theory is sacrosanct,then the case is as it is.The conclusion derived from the case will also be correct,true and acceptable.However,traditional ethicists used to apply their ethical theories,but they did not know which moral theory was effective on the ground level of reality.The study will show readers how ethical theories are in conflict with each other in the case of euthanasia.In more precise words,“which ethical theories are said to be applied,meta-ethical or normative,or both for the resolution of ethical problems?If normative theories are said to be applied,how the application can take place when it is contrary to our experience,that(then)in a situation of moral crises,no one really applies a theory?”For that,my argument is the linear model has failed because it is rigid,often ignores the agents’intrinsic values,and has no space to amend it,no matter how bizarre the consequence is.Its alternative is the Inductive model.For that,the paper will take three moral principles(autonomy,beneficence including maleficence,and justice)of Beauchamp&Childress.This suggests us for resolving value-laden moral problems,we should consider some steps such as a)recognising moral issues to start with;b)developing the moral imagination;c)sharpening analytical/critical skills;d)testing out disagreements;e)effecting decisions and behavior;and f)implementation,closure,and process are of vital importance,in other words,it starts with the free and informed consensus of all interested parties,but this model also has been failed because the model could not give a systematic organization to their way of resolution.Here,my argument is that the inductive model provides resolution of the practical problem but ignores what is ethically obligatory,permissible,or wrong in that situation,and there are no appropriate suggestions in the case of a moral crisis.

2011—2015年国际应用行为分析热点研究——以《Journal of Applied Behavior Analysis》为例

为了探究应用行为分析在国外的研究成果和动态,利用共词分析的原理对2011—2015年JABA刊文的关键词进行了分析,结果显示近五年国外应用行为分析研究热点有自闭症谱系障碍、功能分析、区别性强化、口语行为、进食障碍等。对这些热点进行分类,探讨了各领域所处的研究地位,最后提出我国学界不仅要加强应用行为分析在特殊儿童问题行为管理和干预中的运用,也要把它推广到其他领域。

Changes in Nurses'Ethical Practices in Organ Transplant Nursing Using Action Research

The purpose of this study is to investigate how participation in action research will change nursing activities in dealing with ethical issues experienced in daily nursing settings of organ transplantation. The action research here is comprised of four types of sessions: clarification of wishes (1st session), meetings to talk about matters experienced, study meetings, and reflections (final session). In the first and final sessions, group interviews about ethical practices were conducted. Recorded data from the interviews and 4th meeting to talk about experiences were analyzed using WordMiner1.5. Participants had the individual need, “wish to improve understanding of ethics in their own skills to promote ethical practices and ethical interests”. Then, they became aware of “ethical practice in placing importance on the relationship with patients/their families and ethics attitudes as nurses”. This awareness was connected to “sharing ideas and information with medical staff, awareness of and action suitable for ethics issues, and increased interest in ethics issues”. Like this, the awareness of ethical practices has expanded from individuals to the relationship with patients/their families and sharing ideas with medical staff, and this has developed into self-development. The findings suggest the importance of an organizational culture that addresses ethics to improve practical ethics skills. The findings also suggest that it would be necessary for an organization to take long-term actions to addresses ethical issues in wards or hospitals.