A Novel System for Moving Object Detection Using Bionic Compound Eyes

Conventional moving target detection focuses on algorithms to improve detection efficiency. These algorithms pay less attention to the image acquisition means, and usually solve specific problems. This often results in poor flexibility and reus- ability. Insect compound eyes offer unique advantages for moving target detection and these advantages have attracted the attention of many researchers in recent years. In this paper we proposed a new system for moving target detection. We used the detection mechanism of insect compound eyes for the simulation of the characteristics of structure, control, and function. We discussed the design scheme of the system, the development of the bionic control circuit, and introduced the proposed mathe- matical model of bionic cqmpound eyes for data acquisition and object detection. After this the integrated system was described and discussed. Our paper presents a novel approach for moving target detection. This approach effectively tackles some of the well-known problems in the field of view, resolution, and real-time processing problems in moving target detection.

A network pharmacology-based investigation of the mechanism of action of chrysanthemum in treating dry eye

Background:Dry eye is a chronic inflammatory disease of the ocular surface that is caused by multiple factors,characterized by pain,visual disturbance,and ocular damage.It is a common ophthalmic disease worldwide and a hot research field for scholars both domestically and internationally.This article employs network pharmacology methods to analyze the mechanism of Chrysanthemum in treating dry eye,which is a promising approach.Methods:The TCMSP(http://tcmspw.com/tcmsp.php)was used to screen for candidate active ingredient molecules of chrysanthemum with oral bioavailability≥30%and drug similarity to chrysanthemum≥0.18 as parameters.The active ingredients of chrysanthemum were searched using the“Related Targets”column in the TCMSP,followed by target prediction.Subsequently,Cytoscape 3.6.0 was employed to construct a compound-target network for chrysanthemum.The Online Mendelian Inheritance in Man and DisGeNET databases were used to identify pathogenic genes associated with dry eye.Furthermore,the STRING database was used to construct an interaction network and bar graph of intersecting target proteins in chrysanthemum to analyze protein interactions and core targets.To obtain key targets of active ingredients of chrysanthemum for treating dry eye,active ingredients targets of chrysanthemum and dry eye targets were intersected using Venny.Finally,a drug-active ingredient-key target-disease network was constructed.Gene Ontology functional annotation of key targets was performed using the WEBGESTALT database,and Kyoto Encyclopedia of Genes and Genomes pathway enrichment was performed using the REACTOM database.Results:Eighty active ingredients of chrysanthemum corresponding to targets were obtained.Among active ingredients,508 predicted targets were identified,along with 4180 genes associated with dry eye and 45 key targets of chrysanthemum for treating dry eye.The functions of key targets primarily include regulation of gene expression,oxidative stress,immune response,apoptosis,proliferation,regulation of cellular inflammation-related factors,and angiogenesis.The primary pathways associated with key targets include interleukin signaling,metabolism,cytokine signaling in the immune system,immune system,and signal transduction.Conclusion:Chrysanthemum facilitates regulation through multiple molecules,targets,and pathways for treating dry eye,primarily inhibiting inflammation-related factors and pathways,thereby reducing inflammation of lacrimal gland tissue and improving dry eye.

Snake-Hot-Eye-Assisted Multi-Process-Fusion Target Tracking Based on a Roll-Pitch Semi-strapdown Infrared Imaging Seeker

Aiming at intercepting large maneuvering targets precisely,the guidance law of advanced self-seeking missiles requires not only inertial line-of-sight(LOS)angular rate but also target maneuvering acceleration.Moreover,the semi-strapdown stabilization platform has lost the ability to measure the inertial LOS angular rate directly,which needs to be extracted by numerical calculation.The differential operation commonly used in traditional methods can magnify the measurement error of the sensor,resulting in insufficient calculation accuracy of the line-of-sight angular rate.By analyzing the mathematical relationship between the missile-target relative motion and the angle tracking system,a multi-process-fusion integrated filter model of relative motion and angle tracking is presented.To overcome the defect that the infrared seeker cannot directly measure the missile-target distance,following the snake-hot-eye visual mechanism,a visual bionic imaging guidance method of estimating the missile-target relative distance from the infrared images is proposed to improve the observability of the filter model.Finally,target-tracking simulations verify that the estimation accuracy of target acceleration is improved by four times.

Hippo signaling:bridging the gap between cancer and neurodegenerative disorders

During development,regulation of organ size requires a balance between cell proliferation,growth and cell death.Dysregulation of these fundamental processes can cause a variety of diseases.Excessive cell proliferation results in cancer whereas excessive cell death results in neurodegenerative disorders.Many signaling pathways known-to-date have a role in growth regulation.Among them,evolutionarily conserved Hippo signaling pathway is unique as it controls both cell proliferation and cell death by a variety of mechanisms during organ sculpture and development.Neurodegeneration,a complex process of progressive death of neuronal population,results in fatal disorders with no available cure to date.During normal development,cell death is required for sculpting of an organ.However,aberrant cell death in neuronal cell population can result in neurodegenerative disorders.Hippo pathway has gathered major attention for its role in growth regulation and cancer,however,other functions like its role in neurodegeneration are also emerging rapidly.This review highlights the role of Hippo signaling in cell death and neurodegenerative diseases and provide the information on the chemical inhibitors employed to block Hippo pathway.Understanding Hippo mediated cell death mechanisms will aid in development of reliable and effective therapeutic strategies in future.

Biological Eagle-eye Inspired Target Detection for Unmanned Aerial Vehicles Equipped with a Manipulator

Inspired by eagle eye mechanisms,the structure and information processing characteristics of the eagle′s visual system are used for the target capture task of an unmanned aerial vehicle(UAV)with a mechanical arm.In this paper,a novel eagle-eye inspired multi-camera sensor and a saliency detection method are proposed.A combined camera system is built by simulating the double fovea structure on the eagle retina.A saliency target detection method based on the eagle midbrain inhibition mechanism is proposed by measuring the static saliency information and dynamic features.Thus,salient targets can be accurately detected through the collaborative work between different cameras of the proposed multi-camera sensor.Experimental results show that the eagle-eye inspired visual system is able to continuously detect targets in outdoor scenes and that the proposed algorithm has a strong inhibitory effect on moving background interference.