BACKGROUND Behavioral activation therapy(BA)is as effective as cognitive behavior therapy(CBT)in treating depression and can be delivered by practitioners with much less psychological training,making it particularly s...BACKGROUND Behavioral activation therapy(BA)is as effective as cognitive behavior therapy(CBT)in treating depression and can be delivered by practitioners with much less psychological training,making it particularly suitable for low resource settings.BA that is culturally adapted for Muslims(BA-M)is a culturally adapted form of BA that has been found acceptable and feasible for Muslims with depression in the United Kingdom and Turkey;however,this is the first time that its efficacy has been determined through a definitive randomized controlled trial.AIM To compare the effectiveness of BA-M with CBT for Muslim patients with depression in Pakistan.METHODS One hundred and eight patients were randomized 1:1 to treatment arms in a parallel-group randomized controlled trial in hospital or community sites in Lahore,Pakistan.Recruitment followed self-referral or referrals from clinicians,consultants or relevant professionals at each site.Four measures were recorded by blinded assessors:The patient health questionnaire-9(PHQ-9);the BA for depression scale short form(BADS-SF);symptom checklist-revised and the World Health Organization Quality-of-Life Brief Scale.All measures were recorded at baseline and post treatment;PHQ-9 and BADS-SF were also recorded at each session and at three month follow up.The primary analysis was to regress the PHQ-9 score after therapy upon the PHQ-9 score before therapy(baseline)and the type of therapy given,that is,analysis of covariance.In addition,analysis using PHQ-9 scores collected at each therapy session was employed in a 2-level regression model.RESULTS Patients in the BA-M arm experienced greater improvement in PHQ-9 score of 1.95 units compared to the CBT arm after adjusting for baseline values(P=0.006)The key reason behind this improvement was that patients were retained in therapy longer under BA-M,in which patients were retained for an average 0.75 sessions more than CBT patients(P=0.013).Patients also showed significant differences on physical(P<0.001),psychological(P=0.004)and social(P=0.047)domains of Quality of Life(QoL)at post treatment level,indicating an increased QoL in the BA-M group as compared to the treatment as usual group.Some baseline differences were noted in both groups for BA scores and two domains of QoL scale:Physical and environment,which might have influenced the results,though the BA-M group showed more improvement at completion of therapy.CONCLUSION Results proved the efficacy of BA-M in reducing symptoms for depressed patients in Pakistan,indicating BA-M is a promising treatment modality for depression in future,particularly in low resource settings.展开更多
Exploration of ways to improve the subjective welfare of residents is an important area of current academic research.Using data from the China Family Panel Studies survey conducted in 2010,this paper investigated the ...Exploration of ways to improve the subjective welfare of residents is an important area of current academic research.Using data from the China Family Panel Studies survey conducted in 2010,this paper investigated the impact of clan culture on the mental health of elderly people in rural China.The results demonstrated that clan culture can significantly decrease the depression score of the rural elderly.Further,there was no gender difference with respect to the impact of clan culture on the depression score of the elderly.At the same time,the positive effects of clan culture on the depression score of the elderly have gradually weakened with economic development.Exploration of the mechanisms involved indicated that in areas with stronger clan culture,older people receive more social support.This study enriches our understanding of the impact of informal institutions on the welfare of rural residents.At the same time,it can also provide a certain decisionmaking reference for the government to formulate relative poverty relief strategies in a new stage of poverty alleviation.展开更多
To construct an effective circular mix-culture model and investigate its culture capacity,we established one small and one large systems,with white shrimp(Litopenaeus vannamei)and razor clam(Sinonovacula constricta)cu...To construct an effective circular mix-culture model and investigate its culture capacity,we established one small and one large systems,with white shrimp(Litopenaeus vannamei)and razor clam(Sinonovacula constricta)cultured in separate ponds.The culture water from the L.vannamei was pumped to the S.constricta,and the culture water from the S.constricta overflowed back into the L.vannamei via gravity.In trial I,we tested four culture densities(groups 1–4),and monitored water quality,growth indices,and digestive and immune enzyme activities.From the results,the nitrogen and phosphorus levels generally increased then declined after 56 days,and were lower in groups 1 and 2.The specific growth rate of group 2 was the highest.After 56 days,activities of four digestive enzymes were increased in group 2,and lysozyme activity was significantly decreased in S.constricta in groups 1–4;Alkaline phosphatase activity of L.vannamei was increased in group 3,but decreased in S.constricta in groups 2–4;Acid phosphatase activity was significantly higher in groups 1–3(P<0.05),while SOD and CAT activities were significantly elevated in group 2(P<0.05).Thus,we applied group 2 density for trial II.In trial II,nitrogen and phosphorus concentrations declined significantly during the latter stages,and growth indices were higher than the control(P<0.05).The yields of L.vannamei and S.constricta were significantly higher than the control(P<0.05).The results revealed a good circular mix-culture system with the optimal culture capacity for L.vannamei(40 ind m^(−2))and S.constricta(300 ind m^(−2)),which provided a reference for the future culture of them.展开更多
This study dealt with the rhythmic Qian 3410 of the intersalt shale series in the Qianjiang Depression,in which the geological condition for oil accumulation in the rhythmic shale was investigated by using the basic d...This study dealt with the rhythmic Qian 3410 of the intersalt shale series in the Qianjiang Depression,in which the geological condition for oil accumulation in the rhythmic shale was investigated by using the basic drilling,core and well logging data,as well as data obtained from the thin section identification,SEM,mercury injection,X-ray diffraction and rock freezing heat analyses.The study result indicated that:1)the intersalt shale series are characterized by TOC in a range of 0.35%-6.38%(averaging 3.19%),Types I and II1 organic matter,and from immature to mature oil,indicative of a potential for generating a great volume of immature oil;2)in the target layer,mineral compositions are complicated,which can divide into argillaceous dolomite facies,argillaceous limestone facies,dolomitic mudstone facies,and calcium-mirabilite-filling dolomitic mudstone facies;and 3)of them,the argillaceous dolomite facies is the most contributory,with reservoir spaces consisting of intergranular pores as dominant,as well as rare dissolution pores and seams.It is characterized by high organic abundance(4.23%-6.38%),high content of brittle mineral(50%-71%),low content of clay mineral(18%-33%),high porosity(10.8%-26.3%)and good oil-bearing properties(S1 distributed in 3.48-5.64 mg/g,and S1/TOC value in a range of 348-564 oil mg/g).Therefore,the argillaceous dolomite facies was considered the key target series to be explored for the intersalt shale oil in the study area in the coming days.展开更多
In the context of the cultural development of the new era and the burgeoning spiritual demands of the people,there has been a remarkable surge in the proliferation of traditional Chinese cultural programs.The“Chinese...In the context of the cultural development of the new era and the burgeoning spiritual demands of the people,there has been a remarkable surge in the proliferation of traditional Chinese cultural programs.The“Chinese Festivals”series,produced by Henan TV,standing out as an engaging TV program that showcases traditional Chinese culture,has rapidly captivated a diverse audience across different age groups,creating a rich,multi-dimensional,and cross-media cultural communication ecosystem.The program strategically selects symbolic elements by systematically categorizing and organizing traditional Chinese cultural symbols to create a rich cultural space.It employs cutting-edge scientific and technological methods to enrich viewer immersion,crafting media rituals with both temporal significance and a profound sense of media ritual.This approach boosts the program’s popularity and sets a benchmark for industry innovation.By fostering an interactive narrative between mainstream media and the public,the program continuously broadens the scope of the“story world,”fostering a harmonious and structured national cultural community through the creative interpretation of traditional Chinese culture and the evocative crafting of the aesthetic sensibilities inherent in Chinese art.It is worth noting that the phenomenon of aesthetic fatigue besets the development of this serial program.To address this issue and further improve the appeal of the program,a comprehensive approach is required to develop a cohesive narrative mode for the“story world.”This involves harmonizing the interplay between artistic endeavors and technological advancements,synchronizing sensory experiences with the foundational ritualistic elements,and enhancing the effectiveness of the media communication matrix to construct a brand of media culture that has social significance,aesthetic value,and economic profits in the new era.展开更多
Depression is predicted to become the second highest disease burden by 2020 as well as being a common mental health condition across the globe. Nevertheless, the presentation of depression varies depending on several ...Depression is predicted to become the second highest disease burden by 2020 as well as being a common mental health condition across the globe. Nevertheless, the presentation of depression varies depending on several factors with the patient’s cultural background playing a significant role. Although depression is such a universal condition, the manner of how a patient presents not only affects the clinician’s ability to make a diagnosis, but ultimately affects the wellbeing of the patient. It is therefore paramount that as clinicians we appreciate how culture not only affects the presentation of depression but also how cultural beliefs affect the patient’s acceptance of such a diagnosis.展开更多
The Joint Exhibition of Asian Civilizations is an exhibition activity during the Conference on Dialogue of Asian Civilizations, which includes the Art Exhibition and the Cultural Relics Exhibition Series. From May 13 ...The Joint Exhibition of Asian Civilizations is an exhibition activity during the Conference on Dialogue of Asian Civilizations, which includes the Art Exhibition and the Cultural Relics Exhibition Series. From May 13 to August 11,2019, the Cultural Relics Exhibition,"the Splendor of Asia 一 an Exhibition of Asian Civilizations", is opened at National Museum of China. Those exhibited are 45 1 cultural relics from 47 Asian countries and another 2 countries with ancient civilizations, i.e., Greece and Egypt. Among them were 1 09 Chinese relics, including Bronze Statue of Yi, Changxin Palace Lamp and other national treasures.展开更多
Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the ...Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the hippocampal neurovascular unit. To test this hypothesis, neurons, astrocytes and endothelial cells were isolated from the brain tissues of rat embryos and newborn rats. Hippocampal neurovascular unit co-cultures were produced using the Transwell chamber co-culture system. A model of diabetes-related depression was generated by adding 150 mM glucose and 200 μM corticosterone to the culture system and compared with the neuron + astrocyte and astrocyte + endothelial cell co-culture systems. Western blot assay was used to measure levels of structural proteins in the hippocampal neurovascular unit co-culture system. Levels of basic fibroblast growth factor, angiogenic factor 1, glial cell line–derived neurotrophic factor, transforming growth factor β1, leukemia inhibitory factor and 5-hydroxytryptamine in the hippocampal neurovascular unit co-culture system were measured by enzyme-linked immunosorbent assay. Flow cytometry and terminal deoxynucleotidyl transferase(TdT)-mediated dUTP nick end labeling staining was used to assess neuronal apoptosis in the hippocampal neurovascular unit. The neurovascular unit triple cell co-culture system had better barrier function and higher levels of structural and secretory proteins than the double cell co-culture systems. In comparison, in the model of diabetes-related depression, the neurovascular unit was damaged with decreased barrier function, poor structural integrity and impaired secretory function. Moreover, neuronal apoptosis was markedly increased, and 5-hydroxytryptamine levels were reduced. These results suggest that diabetes-related depression is associated with structural and functional damage to the neurovascular unit. Our findings provide a foundation for further studies on the pathogenesis of diabetes-related depression.展开更多
The Chezhen depression,located in the south of Bohai Bay Basin,is an oil-producing basin in China. The third and fourth members of the Shahejie Formation(E(s3) and E(s4)) are the main source rock series in the Chezhen...The Chezhen depression,located in the south of Bohai Bay Basin,is an oil-producing basin in China. The third and fourth members of the Shahejie Formation(E(s3) and E(s4)) are the main source rock series in the Chezhen depression. Widespread overpressures occurred in the E(s3) and E(s4) from the depths of approximately 2 000 to 4 600 m,with the maximum pressure coefficient of 1.98 from drillstem tests(DST). Among the sonic,resistivity and density logs,sonic-log is the only reliable pressure indicator and can be used to predict the pore pressure with Eaton's method. All the overpressured mudstones in the source rock series have higher acoustic traveltimes compared with normally pressured mudstones at a given depth. The overpressured mudstones in the E(s3) and E(s4) units are characterized by a normal geothermal gradient,high average density values up to 2.5 g/cm^3,strong present-day hydrocarbon generation capability,abundant mature organic matter and high contents of residual hydrocarbons estimated by the Rock-Eval S1 values and chloroform-soluble bitumen "A" values. All suggest that the dominant mechanism for overpressure in the mudstones of source rock series in the Chezhen depression is hydrocarbon generation. A comparison between the matrix porosity of the normally pressured sandstones and overpressured sandstones,the quantitative evaluation of porosity loss caused by compaction and the conventional thin section inspection demonstrate that the sandstones in the Chezhen depression were normally compacted. The high contents of hydrocarbons in the overpressured reservoirs prove that the overpressure in the sandstones of the source rock series was caused by pressure transmission from the source rocks.展开更多
文摘BACKGROUND Behavioral activation therapy(BA)is as effective as cognitive behavior therapy(CBT)in treating depression and can be delivered by practitioners with much less psychological training,making it particularly suitable for low resource settings.BA that is culturally adapted for Muslims(BA-M)is a culturally adapted form of BA that has been found acceptable and feasible for Muslims with depression in the United Kingdom and Turkey;however,this is the first time that its efficacy has been determined through a definitive randomized controlled trial.AIM To compare the effectiveness of BA-M with CBT for Muslim patients with depression in Pakistan.METHODS One hundred and eight patients were randomized 1:1 to treatment arms in a parallel-group randomized controlled trial in hospital or community sites in Lahore,Pakistan.Recruitment followed self-referral or referrals from clinicians,consultants or relevant professionals at each site.Four measures were recorded by blinded assessors:The patient health questionnaire-9(PHQ-9);the BA for depression scale short form(BADS-SF);symptom checklist-revised and the World Health Organization Quality-of-Life Brief Scale.All measures were recorded at baseline and post treatment;PHQ-9 and BADS-SF were also recorded at each session and at three month follow up.The primary analysis was to regress the PHQ-9 score after therapy upon the PHQ-9 score before therapy(baseline)and the type of therapy given,that is,analysis of covariance.In addition,analysis using PHQ-9 scores collected at each therapy session was employed in a 2-level regression model.RESULTS Patients in the BA-M arm experienced greater improvement in PHQ-9 score of 1.95 units compared to the CBT arm after adjusting for baseline values(P=0.006)The key reason behind this improvement was that patients were retained in therapy longer under BA-M,in which patients were retained for an average 0.75 sessions more than CBT patients(P=0.013).Patients also showed significant differences on physical(P<0.001),psychological(P=0.004)and social(P=0.047)domains of Quality of Life(QoL)at post treatment level,indicating an increased QoL in the BA-M group as compared to the treatment as usual group.Some baseline differences were noted in both groups for BA scores and two domains of QoL scale:Physical and environment,which might have influenced the results,though the BA-M group showed more improvement at completion of therapy.CONCLUSION Results proved the efficacy of BA-M in reducing symptoms for depressed patients in Pakistan,indicating BA-M is a promising treatment modality for depression in future,particularly in low resource settings.
基金financial support provided by the Fundamental Research Funds for the Central Universities,China(BLX201945)。
文摘Exploration of ways to improve the subjective welfare of residents is an important area of current academic research.Using data from the China Family Panel Studies survey conducted in 2010,this paper investigated the impact of clan culture on the mental health of elderly people in rural China.The results demonstrated that clan culture can significantly decrease the depression score of the rural elderly.Further,there was no gender difference with respect to the impact of clan culture on the depression score of the elderly.At the same time,the positive effects of clan culture on the depression score of the elderly have gradually weakened with economic development.Exploration of the mechanisms involved indicated that in areas with stronger clan culture,older people receive more social support.This study enriches our understanding of the impact of informal institutions on the welfare of rural residents.At the same time,it can also provide a certain decisionmaking reference for the government to formulate relative poverty relief strategies in a new stage of poverty alleviation.
基金supported by the National Key Research and Development Plan(No.2019YFD0900400)the Ear marked Fund for Modern Agro-Industry Technology Research System,China(No.CARS-47)sponsored by the K.C.Wong Magna Fund in Ningbo University.
文摘To construct an effective circular mix-culture model and investigate its culture capacity,we established one small and one large systems,with white shrimp(Litopenaeus vannamei)and razor clam(Sinonovacula constricta)cultured in separate ponds.The culture water from the L.vannamei was pumped to the S.constricta,and the culture water from the S.constricta overflowed back into the L.vannamei via gravity.In trial I,we tested four culture densities(groups 1–4),and monitored water quality,growth indices,and digestive and immune enzyme activities.From the results,the nitrogen and phosphorus levels generally increased then declined after 56 days,and were lower in groups 1 and 2.The specific growth rate of group 2 was the highest.After 56 days,activities of four digestive enzymes were increased in group 2,and lysozyme activity was significantly decreased in S.constricta in groups 1–4;Alkaline phosphatase activity of L.vannamei was increased in group 3,but decreased in S.constricta in groups 2–4;Acid phosphatase activity was significantly higher in groups 1–3(P<0.05),while SOD and CAT activities were significantly elevated in group 2(P<0.05).Thus,we applied group 2 density for trial II.In trial II,nitrogen and phosphorus concentrations declined significantly during the latter stages,and growth indices were higher than the control(P<0.05).The yields of L.vannamei and S.constricta were significantly higher than the control(P<0.05).The results revealed a good circular mix-culture system with the optimal culture capacity for L.vannamei(40 ind m^(−2))and S.constricta(300 ind m^(−2)),which provided a reference for the future culture of them.
基金funded by the 2018 Undergraduate Training Program for Innovation and Entrepreneurship of Yangtze University,the project number is 2018267.
文摘This study dealt with the rhythmic Qian 3410 of the intersalt shale series in the Qianjiang Depression,in which the geological condition for oil accumulation in the rhythmic shale was investigated by using the basic drilling,core and well logging data,as well as data obtained from the thin section identification,SEM,mercury injection,X-ray diffraction and rock freezing heat analyses.The study result indicated that:1)the intersalt shale series are characterized by TOC in a range of 0.35%-6.38%(averaging 3.19%),Types I and II1 organic matter,and from immature to mature oil,indicative of a potential for generating a great volume of immature oil;2)in the target layer,mineral compositions are complicated,which can divide into argillaceous dolomite facies,argillaceous limestone facies,dolomitic mudstone facies,and calcium-mirabilite-filling dolomitic mudstone facies;and 3)of them,the argillaceous dolomite facies is the most contributory,with reservoir spaces consisting of intergranular pores as dominant,as well as rare dissolution pores and seams.It is characterized by high organic abundance(4.23%-6.38%),high content of brittle mineral(50%-71%),low content of clay mineral(18%-33%),high porosity(10.8%-26.3%)and good oil-bearing properties(S1 distributed in 3.48-5.64 mg/g,and S1/TOC value in a range of 348-564 oil mg/g).Therefore,the argillaceous dolomite facies was considered the key target series to be explored for the intersalt shale oil in the study area in the coming days.
基金the project“Research on the Digitalized Living Inheritance and Development of the Yellow River Cultural Gene,”a project of Humanities and Social Sciences Research of Higher Education Institutes in Henan Province(Project No.2024-ZDJH-770).
文摘In the context of the cultural development of the new era and the burgeoning spiritual demands of the people,there has been a remarkable surge in the proliferation of traditional Chinese cultural programs.The“Chinese Festivals”series,produced by Henan TV,standing out as an engaging TV program that showcases traditional Chinese culture,has rapidly captivated a diverse audience across different age groups,creating a rich,multi-dimensional,and cross-media cultural communication ecosystem.The program strategically selects symbolic elements by systematically categorizing and organizing traditional Chinese cultural symbols to create a rich cultural space.It employs cutting-edge scientific and technological methods to enrich viewer immersion,crafting media rituals with both temporal significance and a profound sense of media ritual.This approach boosts the program’s popularity and sets a benchmark for industry innovation.By fostering an interactive narrative between mainstream media and the public,the program continuously broadens the scope of the“story world,”fostering a harmonious and structured national cultural community through the creative interpretation of traditional Chinese culture and the evocative crafting of the aesthetic sensibilities inherent in Chinese art.It is worth noting that the phenomenon of aesthetic fatigue besets the development of this serial program.To address this issue and further improve the appeal of the program,a comprehensive approach is required to develop a cohesive narrative mode for the“story world.”This involves harmonizing the interplay between artistic endeavors and technological advancements,synchronizing sensory experiences with the foundational ritualistic elements,and enhancing the effectiveness of the media communication matrix to construct a brand of media culture that has social significance,aesthetic value,and economic profits in the new era.
文摘Depression is predicted to become the second highest disease burden by 2020 as well as being a common mental health condition across the globe. Nevertheless, the presentation of depression varies depending on several factors with the patient’s cultural background playing a significant role. Although depression is such a universal condition, the manner of how a patient presents not only affects the clinician’s ability to make a diagnosis, but ultimately affects the wellbeing of the patient. It is therefore paramount that as clinicians we appreciate how culture not only affects the presentation of depression but also how cultural beliefs affect the patient’s acceptance of such a diagnosis.
文摘The Joint Exhibition of Asian Civilizations is an exhibition activity during the Conference on Dialogue of Asian Civilizations, which includes the Art Exhibition and the Cultural Relics Exhibition Series. From May 13 to August 11,2019, the Cultural Relics Exhibition,"the Splendor of Asia 一 an Exhibition of Asian Civilizations", is opened at National Museum of China. Those exhibited are 45 1 cultural relics from 47 Asian countries and another 2 countries with ancient civilizations, i.e., Greece and Egypt. Among them were 1 09 Chinese relics, including Bronze Statue of Yi, Changxin Palace Lamp and other national treasures.
基金supported by the National Natural Science Foundation of China,No.81373578(to YHW),81573965(to YHW)the Natural Science Foundation of Hunan Province of China,No.2017JJ3241(to JL)the Education Department Scientific Research Foundation of Hunan Province of China,No.17C1229(to JL)
文摘Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the hippocampal neurovascular unit. To test this hypothesis, neurons, astrocytes and endothelial cells were isolated from the brain tissues of rat embryos and newborn rats. Hippocampal neurovascular unit co-cultures were produced using the Transwell chamber co-culture system. A model of diabetes-related depression was generated by adding 150 mM glucose and 200 μM corticosterone to the culture system and compared with the neuron + astrocyte and astrocyte + endothelial cell co-culture systems. Western blot assay was used to measure levels of structural proteins in the hippocampal neurovascular unit co-culture system. Levels of basic fibroblast growth factor, angiogenic factor 1, glial cell line–derived neurotrophic factor, transforming growth factor β1, leukemia inhibitory factor and 5-hydroxytryptamine in the hippocampal neurovascular unit co-culture system were measured by enzyme-linked immunosorbent assay. Flow cytometry and terminal deoxynucleotidyl transferase(TdT)-mediated dUTP nick end labeling staining was used to assess neuronal apoptosis in the hippocampal neurovascular unit. The neurovascular unit triple cell co-culture system had better barrier function and higher levels of structural and secretory proteins than the double cell co-culture systems. In comparison, in the model of diabetes-related depression, the neurovascular unit was damaged with decreased barrier function, poor structural integrity and impaired secretory function. Moreover, neuronal apoptosis was markedly increased, and 5-hydroxytryptamine levels were reduced. These results suggest that diabetes-related depression is associated with structural and functional damage to the neurovascular unit. Our findings provide a foundation for further studies on the pathogenesis of diabetes-related depression.
基金sponsored by the China National Science and Technology Major Project (No. 2016ZX05006003-001)the Programme of Introducing Talents of Discipline to Universities (No. B14031)+1 种基金the National Natural Science Foundation of China (Nos. 41572114, 41302110)The SINOPEC Shengli Oilfield is thanked for providing background geological data and support
文摘The Chezhen depression,located in the south of Bohai Bay Basin,is an oil-producing basin in China. The third and fourth members of the Shahejie Formation(E(s3) and E(s4)) are the main source rock series in the Chezhen depression. Widespread overpressures occurred in the E(s3) and E(s4) from the depths of approximately 2 000 to 4 600 m,with the maximum pressure coefficient of 1.98 from drillstem tests(DST). Among the sonic,resistivity and density logs,sonic-log is the only reliable pressure indicator and can be used to predict the pore pressure with Eaton's method. All the overpressured mudstones in the source rock series have higher acoustic traveltimes compared with normally pressured mudstones at a given depth. The overpressured mudstones in the E(s3) and E(s4) units are characterized by a normal geothermal gradient,high average density values up to 2.5 g/cm^3,strong present-day hydrocarbon generation capability,abundant mature organic matter and high contents of residual hydrocarbons estimated by the Rock-Eval S1 values and chloroform-soluble bitumen "A" values. All suggest that the dominant mechanism for overpressure in the mudstones of source rock series in the Chezhen depression is hydrocarbon generation. A comparison between the matrix porosity of the normally pressured sandstones and overpressured sandstones,the quantitative evaluation of porosity loss caused by compaction and the conventional thin section inspection demonstrate that the sandstones in the Chezhen depression were normally compacted. The high contents of hydrocarbons in the overpressured reservoirs prove that the overpressure in the sandstones of the source rock series was caused by pressure transmission from the source rocks.