Gestational diabetes mellitus combined with fulminant type 1 diabetes mellitus, four cases of double diabetes: A case report

BACKGROUND Fulminant type 1 diabetes mellitus(FT1DM)that occurs during pregnancy or the perinatal period is known as pregnancy-related FT1DM(PF),always without history of abnormal glucose metabolism.Here,we present four patients who developed FT1DM during treatment but were first diagnosed with gestational diabetes mellitus(GDM).CASE SUMMARY The clinical data of four patients with GDM combined with FT1DM admitted to our hospital between July 2018 and April 2021 were collected,and the patients and their infants were followed up.All patients were diagnosed with GDM during the second trimester and were treated.The blood glucose level elevated suddenly during the third trimester and then were diagnosed with FT1DM.Two patients had an insulin allergy,and two had symptoms of upper respiratory tract infection before onset.One patient developed ketoacidosis,and three developed ketosis.Two patients had cesarean section deliveries,and two had vaginal deliveries.The growth and development of the infants were normal.C-peptide levels were lower than those at onset,suggesting progressive impairment of islet function.The frequencies of the DRB109:01,DQB103:03,DQA103:02,DPA101:03,DPA102:02,DPB105:01,DRB401:03,G 01:01,and G 01:04 human leukocyte antigen(HLA)-G alleles were high in the present study.CONCLUSION In comparison with pregnancy-associated FT1DM(PF),patients with GDM combined with FT1DM had an older age of onset,higher body mass index,slower onset,fewer prodromal symptoms,and less acidosis.The pathogenesis may be due to various factors affecting the already fragileβ-cells of GDM patients with genetically susceptible class II HLA genotypes.We speculate that GDM combined with FT1DM during pregnancy,referred to as“double diabetes,”is a subtype of PF with its own unique characteristics that should be investigated further.

A blockchain bee colony double inhibition labor division algorithm for spatio-temporal coupling task with application to UAV swarm task allocation

It is difficult for the double suppression division algorithm of bee colony to solve the spatio-temporal coupling or have higher dimensional attributes and undertake sudden tasks.Using the idea of clustering,after clustering tasks according to spatio-temporal attributes,the clustered groups are linked into task sub-chains according to similarity.Then,based on the correlation between clusters,the child chains are connected to form a task chain.Therefore,the limitation is solved that the task chain in the bee colony algorithm can only be connected according to one dimension.When a sudden task occurs,a method of inserting a small number of tasks into the original task chain and a task chain reconstruction method are designed according to the relative relationship between the number of sudden tasks and the number of remaining tasks.Through the above improvements,the algorithm can be used to process tasks with spatio-temporal coupling and burst tasks.In order to reflect the efficiency and applicability of the algorithm,a task allocation model for the unmanned aerial vehicle(UAV)group is constructed,and a one-to-one correspondence between the improved bee colony double suppression division algorithm and each attribute in the UAV group is proposed.Task assignment has been constructed.The study uses the self-adjusting characteristics of the bee colony to achieve task allocation.Simulation verification and algorithm comparison show that the algorithm has stronger planning advantages and algorithm performance.

The Optimizing Model and Its Solution for Making Train Working Graph with Computer on Separative Division of Double－Track Lines

The authoros specialize in the field of optunization and automatic programme oftrain working graph. In this peper, at frist, a mixed 0-1 integer progranimingmodel about this problem for duuble-track lines is set up, then the principle andProcess of selution are stated, with an application exaiiiple put forward.

Treatment of Complex Proximal Tibial Fractures (Types V &VI of Schautzker Classification) by Double Plate Fixation with Single Anterior Incision

Background: complex proximal tibial fractures (Types V & VI of Schautzker classification) are the major problems in orthopedic surgery and associated with high complication rates. There are many alternatives in treatment of these fractures. Aim: to evaluate the results of double plating with single anterior incision in complex proximal tibial fractures (Types V& VI of Schautzker classification).Methods and Materials: 22 patients (16 males and 6 females) with Types V and VI of Schautzker classification of proximal tibial fractures (14 cases were Type V and 8 cases were Type VI) were treated by double plating with single anterior incision method between May 2006 and May 2011. The bony and functional outcome was evaluated according to Knee Society Score. Results: According to Knee Society Score, the results were as follows: excellent in 19 patients (86.4%), good in 2 patients (9.1%), fair in 1 patient (4/5%), and poor in no patient (0%).Conclusion: the double plate fixation with single anterior incision is the best, effective and simple procedure in treatment of complex proximal tibial fractures (Types V and VI of Schautzker classification).

Double filtration plasmapheresis for pregnancy with hyperlipidemia in glycogen storage disease type Ia:A case report

BACKGROUND Glycogen storage disease type Ia(GSDIa) is an autosomal recessive inborn error of carbohydrate metabolism that is caused by deficiency of the enzyme glucose-6-phosphatase(G6Pase),leading to disturbed glycogenolysis and gluconeogenesis.Patients with GSDIa show severe fasting hypoglycemia,hyperlipidemia,hyperlactacidemia,and hyperuricemia,which are associated with fatal outcomes in pregnant women and fetuses.CASE SUMMARY Herein,we report the case of a 24-year-old female who on her first visit to the hospital,presented with pregnancy combined with extremely high hyperlipidemia and hyperlactic acidosis with anemia,and frequent hypoglycemia occurred during the treatment.Genetic tests revealed a mutation in the G6Pase gene(G6PC) at 17q21,the patient was finally diagnosed with glycogen storage disease type Ia for the first time after 22 years of inaccurate treatment.She has been treated with a continuous double filtration plasmapheresis(DFPP) strategy to remove blood lipids,and a cornstarch diet therapy.The patient did not develop pancreatitis during the course of the disease and a healthy baby girl weighing 3 kg was delivered.CONCLUSION Patients with GSDIa may be misdiagnosed as epilepsy.DFPP can be used to control hyperlipidemia in GSDIa patients during pregnancy.

Double-directional control bolt support technology and engineering application at large span Y-type intersections in deep coal mines

Under deep and complex geological conditions,severe deformation occurs at intersection points of Y-type roadways with large cross sections during engineering projects in coal mines,especially at junction arches.Based on in-situ investigations and theoretical studies,we have summarized typical forms of destruction and identified high stress and unrestricted support at both sides of junction arch as its main causes.In this study,we also presented double-directional control bolt support technology for a large Y-type span intersection,applied to deep intersection engineering in the Jiahe Coal Mine,which has proved effective.

EFFICIENCY ANALYSIS OF DOUBLE CRANK RING-PLATE-TYPE PIN-CYCLOIDAL GEAR PLANETARY DRIVE

From the general formula for calculating the efficiency of planetary geartrains, the efficiency of the double crank ring-plate-type pin-cycloidal gear planetary drive isderived. To prove the theory, an experimental study has been conducted. The tested value of theefficiency of a sample set of the new-type drive in the experiment agrees with the calculated one.It shows that the new-type drive is of not merely high bearing capacity, but also quite highefficiency.

Mathematical Model and Geometrical Model of Double Pitch ZN-type Worm Gear Set Based on Generation Mechanism

The current researches on the tooth surface mathematical equations and the theory of gearing mainly pay attention to the ordinary type worm gear set（e.g., ZN, ZA, or ZK）. The research of forming mechanism and three-dimensional modeling method for the double pitch worm gear set is not enough. So there are some difficulties in mathematical model deducing and geometry modeling of double pitch ZN-type worm gear set based on generation mechanism. In order to establish the mathematical model and the precise geometric model of double pitch ZN-type worm gear set, the structural characteristics and generation mechanism of the double pitch ZN-type worm gear set are investigated. Mathematical model of the ZN-type worm gear set is derived based on its generation mechanism and the theory of gearing. According to the mathematical model of the worm gear set which has been developed, a geometry modeling method of the double pitch ZN-type worm and worm gear is presented. Furthermore, a geometrical precision calculate method is proposed to evaluate the geometrical quality of the double pitch worm gear set. As a result, the maximum error is less than 6′10–4 mm in magnitude, thus the model of the double pitch ZN-type worm gear set is available to meet the requirements of finite element analysis and engineering application. The derived mathematical model and the proposed geometrical modeling method are helpful to guiding the design, manufacture and contact analysis of the worm gear set.

On Fatou Type Convergence of Convolution Type Double Singular Integral Operators

In this paper, some approximation formulae for a class of convolution type double singular integral operators depending on three parameters of the type(T_λf)(x, y) = ∫_a^b ∫_a^b f(t, s)K_λ(t-x,s-y)dsdt, x,y ∈(a,b), λ ∈ Λ [0,∞),(0.1)are given. Here f belongs to the function space L_1( <a,b >~2), where <a,b> is an arbitrary interval in R. In this paper three theorems are proved, one for existence of the operator(T_λf)(x, y) and the others for its Fatou-type pointwise convergence to f(x_0, y_0), as(x,y,λ) tends to(x_0, y_0, λ_0). In contrast to previous works, the kernel functions K_λ(u,v)don't have to be 2π-periodic, positive, even and radial. Our results improve and extend some of the previous results of [1, 6, 8, 10, 11, 13] in three dimensional frame and especially the very recent paper [15].

Newly-generated Seismic Rupture Zone:Identification,Type Division and Seismogeological Significance

The results of geological research show that those phenomena such as surface geology,geomorphology,deep geophysical field,and time-space distribution of seismicities can be usedas the main seismogeological indicators to identify the newly-generated seismic rupture zone(NSRZ).According to their formation and evolution process,the NSRZs can be divided intothree types:pre-rupture-isolated,quasi-rupture-discontinuous and major-rupture-connected.In a pre-rupture-isolated NSRZ,the seismicity is dominated by medium-small earthquakes.In a quasi-rupture-discontinuous NSRZ,the frequency and intensity of strong earthquakesincrease and there may even be the largest earthquake to occur.A major-rupture-connectedNSRZ is the segment where rupture has entered the mature stage;in such a zone,theintensity and duration of seismic activity depend on the constitutive condition and regionalstress field in the zone.

New Pyrometer with Double Y-type Optical Fibers

Abstract: A new pyrometer, which can solve the affection of emissivity change in temperature measuring, has been developed by double Y - type optical fibers. The mathematical model of the new pyrometer is presented and the errors of the new pyrometer are analyzed.

New Double Integrals Weighted Cebysev Type Inequalities

In the last years, the theory of integral inequalities are playing a very significant role in all fields of mathematics, many monographs have been devoted to this subject and present a very active and attractive field of research, the applications of integral inequalities have known a great development in many branches of mathematics in statistics, differential equations and numerical integration, The aim of this paper is to establish new extension of the weighted montgomery identity for double integrals then used it to establish new t^eby^evtype inequalities.

A New Type of Double-Lumen Catheter to Replace Current One in RCA

Objective: To replace the peripheral venous puncture for blood sampling with taking blood samples extracorporally from arterial line before predilution during RCA-CRRT performed. Methods: A new type of double-lumen femoral catheter was used instead of the current tubes. The new type of double-lumen tube had a greater distance from the inner venous ports to the inner arterial ports than current tubes. The minimum distance from the venous port to the arterial port was greatly lengthened. Replacement solution contained citrate, zero Ca2+, zero bicarbonate, low Na+. Blood samples were synchronously collected from the arterial line before the infusion of citrate replacement fluid and from the peripheral vein. The iCa concentration data of two groups were analyzed to observe the difference between iCa concentration levels in the arterial line and in peripheral vein;the anticoagulant effect of RCA and possible complications were observed, such as bleeding, clottings and hypocalcaemia. Results: 28 times of RCA-CRRT were performed on17 AKI and CRF patients with active bleeding or at the high risk of bleeding;336 blood samples were collected. Statistics showed that the difference of iCa concentration between arterial line group and the peripheral vein group was not significant (P = 0.9), there is a high degree of similarity between the iCa concentration of arterial line blood and the peripheral venous blood. None of the patients developed citrate toxicity or metabolic alkalosis. None induced bleeding, or bleeding aggravated. No obvious clotting occurred. Systemic calcium concentration was achieved in the ideal range. Conclusion: In clinical practice, the data of iCa concentration from arterial line can be used to replace that from peripheral vein when the new type of double-lumen femoral catheter is placed in femoral vein. RCA-CRRT therapy is safe and effective.

Interlayer distance effects on absorption coefficient and refraction index change in p-type double-δ-doped GaAs quantum wells

In the framework of the Thomas–Fermi(TF) approach, a model for the p-type double-δ-doped(DDD) system in Ga As is presented. This model, unlike other works in the literature, takes into account that the Poisson equation associated with the system is nonlinear. The electronic structure is calculated for heavy and light holes. The changes in the electronic structure result of the distance d between the doped layers are studied. In particular, the relative absorption coefficient as well as the relative refractive index change is calculated as a function of the incident photon energy for heavy holes. The effect of the interlayer distance exhibits, in the absorption coefficient, a red shift of the peak position and a decrease in amplitude when the distance increases. In addition, the relative refractive index change node has a red shift as well as the interlayer distance increases. The calculations show that the effect of the separation between layers has a greater influence on the linear terms. These results are very important for theoretical calculations and engineering of optical and electronic devices based in δ-doped Ga As.

SUPPORT SYSTEM FOR FREE SURFACE GRINDING BASED ON PATCH DIVISION

To obtain accurate forms and surfaces in free surface grinding, it is important to provide grinding conditions suitable for a curved surface. A grinding support system for the free surface （GSX-F） is proposed to help the operator grind a free surface with the high accuracy and the high productivity. To succeed in free surface grinding, the property of a ball type wheel must be known. Therefore, a basic study of free surface grinding with a ball type wheel is carried out based on the grinding center （GC）. Some working points for achieving sufficient accuracy in free surface grinding are discussed. GSX-F is constructed using the patch division method and is used to test grinding. Reasonable results are obtained.

Research and Exploration on the Construction of Double Qualified Teachers in Software Engineering

In order to solve the problem of insufficient integration of school-enterprise supervisors in the current school-enterprise cooperation model,this article introduces the ideas and results of the construction of a team with double-qualified instructors majored in software engineering.Specifically,the integration of production and education are carried out in three stages,i.e.,enterprise cooperation courses,enterprise internship,and graduation design(internship),by taking the software engineering major of the School of Information and Software Engineering of the University of Electronic Science and Technology of China as a case study.

On the structure and representations of non-balanced quantum doubles

For a field k and two finite groups G and X, when G acts on X from the right by group automorphisms, there is a Hopf algebra structure on k-space （kX°P）＊ kG （see Theorem 2.1）, called a non-balanced quantum double and denoted by Dx（G）. In this paper, some Hopf algebra properties of Dx （G） are given, the representation types of Dx （G） viewed as a k-algebra are discussed, the algebra structure and module category over Dx（G） are studied. Since the Hopf algebra structure of non-balanced quantum double DX （G） generMizes the usual quantum double D（G） for a finite group G, all results about Dx（G） in this paper can also be used to describe D（G） as a special case and the universal R-matrix of Dx （G） provides more solutions of Yang-Baxter equation.

On Turán type inequality with doubling weights and A weights

Let Hn be the set of real algebraic polynomials of degree n, whose zeros all lie in the interval [-1,1]. The well known Turán type inequalities tell us that forf（x）∈Hn, it holds ‖f＇‖≥C√n‖f‖. This note deals with the weighted Turán type inequalities with the weights having inner singularities under L^p norm for 0〈p≤∞. Our results essentially extend the result of Wang and Zhou （2002）, and the method used in this paper is simpler and more direct than that of Wang and Zhou （2002）. The results and methods have their own values in approximation theory and computation.

Application of frequency division inversion in the prediction of heterogeneous natural gas hydrates reservoirs in the Shenhu Area,South China Sea

Drilling results suggest that the thickness of natural gas hydrates(NGHs)in the Shenhu Area,South China Sea(SCS)are spatially heterogenous,making it difficult to accurately assess the NGHs resources in this area.In the case that free gas exists beneath hydrate deposits,the frequency of the hydrate deposits will be noticeably attenuated,with the attenuation degree mainly affected by pore development and free gas content.Therefore,the frequency can be used as an important attribute to identify hydrate reservoirs.Based on the time-frequency characteristics of deposits,this study predicted the spatial distribution of hydrates in this area using the frequency division inversion method as follows.Firstly,the support vector machine(SVM)method was employed to study the amplitude versus frequency(AVF)response based on seismic and well logging data.Afterward,the AVF response was introduced as independent information to establish the nonlinear relationship between logging data and seismic waveform.Then,the full frequency band information of the seismic data was fully utilized to obtain the results of frequency division inversion.The inversion results can effectively broaden the frequency band,reflect the NGHs distribution,and reveal the NGHs reservoirs of two types,namely the fluid migration pathway type and the in situ self-generation self-storage diffusion type.Moreover,the inversion results well coincide with the drilling results.Therefore,it is feasible to use the frequency division inversion to predict the spatial distribution of heterogeneous NGHs reservoirs,which facilitates the optimization of favorable drilling targets and is crucial to the resource potential assessment of NGHs.

Supporting Research for ＂Double Teachers＂ Team Construction of School-enterprise Cooperation Take Professional Tourism Management School-enterprise Cooperation ＂Double＂ Teachers Construction as An Example

This paper mainly studies cooperative education problems of tourism management professional school-enterprise cooperation. Since the 1990s, many universities have begun to explore the issue of school-enterprise cooperation in running schools, and tourism management major is one of the popular professional cooperative education, there has been various forms of cooperative education, both success and failure cases. Many scholars take in-depth research of the issues and come up with many innovative ideas. Currently, much tourism management major of higher colleges gradually embarked on the road of school-enterprise cooperation. This study is under the background of the booming Chinese tourism higher education, school-enterprises cooperation have continued deepen, from both theoretical and practical aspects have a deep thinking in tourism management professional school-enterprise cooperative education issues systems.