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Clinical Efficacy Observation of a Jing Ethnic Prescription in Treating Chronic Atrophic Gastritis
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作者 Jinjian Xu Li Wu +3 位作者 Xiaowei He En Zhao Tianwu Lai Man Zhang 《International Journal of Clinical Medicine》 CAS 2024年第11期479-485,共7页
Objective: To observe the clinical efficacy of a Jing ethnic prescription in treating chronic atrophic gastritis (CAG). Methods: A total of 182 CAG patients admitted to our hospital were randomly divided into a contro... Objective: To observe the clinical efficacy of a Jing ethnic prescription in treating chronic atrophic gastritis (CAG). Methods: A total of 182 CAG patients admitted to our hospital were randomly divided into a control group (91 cases) and a treatment group (91 cases) based on their admission order. The control group received conventional treatment, while the treatment group was treated with a Jing ethnic prescription. The clinical efficacy, changes in gastric mucosa-related indicators, and systemic inflammatory markers were compared between the two groups. Results: After treatment, the overall effective rate in the treatment group was higher than that in the control group, but the difference was not statistically significant (P > 0.05). The levels of trefoil factor 2 (TFF2) in the gastric mucosa increased, and the levels of nuclear factor-kappa B (NF-κB) decreased in both groups. However, the improvement in these indicators was significantly better in the treatment group (P Conclusion: The custom formula of the Jing ethnic group shows comparable clinical efficacy to conventional treatment for chronic atrophic gastritis (CAG), but it demonstrates significantly better effects in reducing systemic inflammatory responses. Specifically, the treatment group showed superior results in the following aspects compared to the control group: increased levels of TFF2, decreased levels of NF-κB, and reduced serum levels of IL-6, IL-8, and hs-CRP. 展开更多
关键词 jing Ethnic Prescription Chronic Atrophic Gastritis EFFICACY Inflammatory Cytokines
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Reflections on Studying Huang Di Nei Jing in the West
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作者 Edward Neal 《Chinese Medicine and Culture》 2024年第1期72-76,共5页
Huang Di Nei Jing(《黄帝内经》The Yellow Emperor’s Inner Classic) has been the source text of Chinese medicine knowledge and innovation for over two thousand years. Despite this key relevance, many of its ideas and p... Huang Di Nei Jing(《黄帝内经》The Yellow Emperor’s Inner Classic) has been the source text of Chinese medicine knowledge and innovation for over two thousand years. Despite this key relevance, many of its ideas and practices have proven difficult to understand and implement fully into clinical practice. Cultural and language differences can be compounded with these challenges but may also present new opportunities for advancement and insight when studied by researchers outside of the originating culture. This article introduces the method of Classical-Text Archaeology and delves into the author’s two-decade journey of researching this text, with a discussion on cultural differences and issues of medical scholarship. 展开更多
关键词 Huang Di Nei jing Chinese medicine Nei jing nature-based medicine Classical text research Global health Medical anthropology Classical-Text Archaeology
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Clinical Observation of the Efficacy of a Customized Prescription from the Jing Ethnic Group in Treating Children with Yang Syndrome of Common Cold
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作者 Jinjian Xu Xin Huang +3 位作者 Xiaowei He En Zhao Quan Zhao Jianye Dai 《Open Journal of Epidemiology》 2024年第4期683-689,共7页
Objective: This paper aims to observe the clinical efficacy of a customized prescription from the Jing ethnic group in treating children with Yang syndrome of common cold. Methods: A total of 160 patients diagnosed wi... Objective: This paper aims to observe the clinical efficacy of a customized prescription from the Jing ethnic group in treating children with Yang syndrome of common cold. Methods: A total of 160 patients diagnosed with Yang syndrome of common cold at the pediatric outpatient clinic of Fangchenggang City Traditional Chinese Medicine Hospital from September 2023 to September 2024 were selected and randomly divided into a control group and an observation group, each with 80 cases. The control group was orally administered Compound Paracetamol, Chlorphenamine Maleate, and Caffeine Oral Solution, while the treatment group received the customized prescription from the Jing ethnic group in addition to the treatment given to the control group. Both groups were treated for three days. During the treatment period, if the axillary temperature of the children in both groups reached or exceeded 39.0˚C, Dexibuprofen Oral Solution could be additionally administered. The time of antipyretic onset, the interval before axillary temperature rebounded within 24 hours after the first antipyretic effect, and the highest axillary temperatures on the 1st, 2nd, and 3rd days were compared between the two groups, as well as their therapeutic effects. Results: Compared with the control group, the treatment group had an earlier onset of antipyretic effect (P Conclusion: The customized prescription from the Jing ethnic group for treating children with Yang syndrome of common cold has a rapid onset, a lasting antipyretic duration, and excellent efficacy without significant adverse reactions, making it worthy of clinical promotion. 展开更多
关键词 Pediatric Common Cold Yang Syndrome jing Ethnic Medicine EFFICACY
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Research on the Investigation and Determination of Advantageous Diseases in Jing Ethnic Medicine
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作者 Jinjiang Xu Li Wu +4 位作者 Xiaowei He Yuan Yu En Zhao Tianwu Lai Man Zhang 《Journal of Biosciences and Medicines》 2024年第11期457-462,共6页
Objective: This paper aims to summarize and establish advantageous diseases in Jing ethnic medicine. Methods: The study employed literature review analysis, expert consultation, field investigation, folk visits, and c... Objective: This paper aims to summarize and establish advantageous diseases in Jing ethnic medicine. Methods: The study employed literature review analysis, expert consultation, field investigation, folk visits, and clinical questionnaire surveys to summarize and conclude the advantageous diseases in Jing ethnic medicine. Results: The book “Jing Ethnic Medicine” records a total of 130 single prescriptions, 165 empirical prescriptions, and 99 dietary therapy prescriptions. Among these, the most frequently recorded prescriptions are for colds (17), coughs (22), gastric pain (31), diarrhea (22), abdominal pain (3), rheumatism (8), hepatitis (11), trauma (34, including injuries from poisonous fish, jellyfish stings, and falls), skin diseases (23), postpartum conditions (10), pediatric fever (3), pediatric malnutrition (4), and pediatric diarrhea (7). A total of 38 questionnaires were distributed and all 38 were valid, revealing that the top five advantageous diseases are colds (including pediatric colds and fever), abdominal pain, gastric pain, skin diseases, and bone pain. Conclusion: The advantageous diseases in Jing ethnic medicine are relatively clear, and standardized research on the diagnostic and therapeutic techniques for gastric diseases, pediatric abdominal heat pain (colds), and abdominal pain (gallstones) should be conducted. 展开更多
关键词 jing Ethnic Medicine Advantageous Diseases Protection and Development
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“Three Beauties”Principle in the English Versions of“Jing Ye Si”--Translations by Xu and Fletcher as Examples
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作者 LUO Ya DONG Juan 《Sino-US English Teaching》 2024年第5期242-246,共5页
“Jing Ye Si”is a classical poem with international influence by the Chinese poet Li Bai in the Tang Dynasty,which expresses the poet’s deep nostalgia.This paper compares and analyzes its two English versions transl... “Jing Ye Si”is a classical poem with international influence by the Chinese poet Li Bai in the Tang Dynasty,which expresses the poet’s deep nostalgia.This paper compares and analyzes its two English versions translated by the Chinese translator Xu Yuanchong and the British translator W.J.B.Fletcher based on the“three beauties”principle(beauty in sense,beauty in sound,and beauty in form),and discovers that the English version of Xu basically achieves the unity of the“three beauties”,while the English version of Fletcher realizes the“beauty in sound and form”,but deviates from the“beauty in sense”mainly owing to the inaccurate comprehension of the moon as an image and other factors.This analysis may afford us with certain reference in poetry translation. 展开更多
关键词 “jing Ye Si” “three beauties”principle comparative analysis TRANSLATION
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浅析高校图书馆“jing”文化建设 被引量:6
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作者 吴齐 赵青 祁宁 《沈阳建筑大学学报(社会科学版)》 2008年第2期226-228,共3页
提出了图书馆"jing"文化概念,即对"净、静、敬、竞"四种文化的高度概括,并对图书馆"jing"文化的内涵及其在高校图书馆文化建设中的作用进行阐述。
关键词 高校图书馆 图书馆文化 “jing”文化
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杞精明目汤联合人工泪液对肝肾阴虚型结膜松弛症患者泪液中Th17相关细胞因子的影响
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作者 沙咏怡 赵怡 +4 位作者 涂少华 孔雪晴 夷成龙 陶霓霞 项敏泓 《国际眼科杂志》 CAS 2025年第1期31-36,共6页
目的:观察中药杞精明目汤联合人工泪液治疗对肝肾阴虚型结膜松弛症(CCH)患者泪液中Th17相关细胞因子的改变。方法:收集56例56眼Ⅱ-Ⅲ级肝肾阴虚型CCH患者,随机分为治疗组(杞精明目汤联合人工泪液)26例26眼和对照组(单纯人工泪液)30例30... 目的:观察中药杞精明目汤联合人工泪液治疗对肝肾阴虚型结膜松弛症(CCH)患者泪液中Th17相关细胞因子的改变。方法:收集56例56眼Ⅱ-Ⅲ级肝肾阴虚型CCH患者,随机分为治疗组(杞精明目汤联合人工泪液)26例26眼和对照组(单纯人工泪液)30例30眼,疗程1 mo,观察治疗前后患者的国际眼表疾病指数(OSDI)、泪膜破裂时间(BUT)、泪河高度(TMH)、球结膜充血指数。采集治疗前后CCH患者的泪液,通过流式免疫荧光发光法对患者泪液中Th17相关细胞因子进行检测和分析。结果:治疗组与对照组CCH患者治疗后OSDI、BUT、球结膜充血指数均较治疗前均明显改善(均P<0.01);治疗后治疗组患者TMH较治疗前显著降低(P<0.01),对照组患者治疗前后TMH无差异(P=0.41)。治疗组CCH患者在治疗后泪液中Th17相关细胞因子IL-17A、IL-22、IFN-γ、IL-17F、IL-1β水平较治疗前明显降低(均P<0.01),且治疗组的变化更为显著(均P<0.05);而对照组治疗前后泪液中Th17相关细胞因子无差异(均P>0.05)。治疗后两组CCH患者泪液中IL-6、TNF-α均较治疗前降低(均P<0.05),但治疗组的变化更为显著(均P<0.01)。结论:杞精明目汤联合人工泪液治疗可有效改善肝肾阴虚型结膜松弛症患者眼表微环境,提高泪膜稳定性,抑制眼表炎症,可能与其降低泪液中Th17相关细胞因子的分泌相关。 展开更多
关键词 结膜松弛症 肝肾阴虚型 杞精明目汤 TH17 IL-17
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四个京药制剂稳定性试验研究
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作者 周家福 吴晓燕 易冰 《中国中医药现代远程教育》 2025年第2期97-100,共4页
京族是广西特有且以海为生的海洋少数民族,其民间经方、验方逐渐被遗忘,故开展抢救和挖掘工作迫在眉睫。文章在京族特色经验方的基础上,筛选出治疗外伤、胃病、痹症的京药顺气护胃方、京药补肾壮骨方、京药血府逐瘀方和京药骨外伤方,并... 京族是广西特有且以海为生的海洋少数民族,其民间经方、验方逐渐被遗忘,故开展抢救和挖掘工作迫在眉睫。文章在京族特色经验方的基础上,筛选出治疗外伤、胃病、痹症的京药顺气护胃方、京药补肾壮骨方、京药血府逐瘀方和京药骨外伤方,并通过四种特色京药制剂的研发,确定了制剂原料标准、各组分比例,实现了标准化生产,相比于传统中药汤剂,大大提高了中药用法的一致性、稳定性、便捷性。希望对挖掘、整理京药有效民间方及开发医疗机构制剂起到重要示范作用,为中药新药研究打下良好基础。 展开更多
关键词 京药 京药顺气护胃方 京药补肾壮骨方 京药血府逐瘀方 京药骨外伤方 稳定性试验
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《诗经》“风”义原始与《风》诗文体
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作者 林训涛 《广西师范大学学报(哲学社会科学版)》 2025年第1期137-146,共10页
《诗经》分为风、雅、颂,体现了清晰的文体分类意识。从《毛诗大序》对“风”的定义和阐释出发,考察“风”的字形字义及其所具有的早期社会的文化意蕴,可认为“风”的本义是以容器(食器)又兼礼器的盘(槃)为基础而产生的具有两性关系及... 《诗经》分为风、雅、颂,体现了清晰的文体分类意识。从《毛诗大序》对“风”的定义和阐释出发,考察“风”的字形字义及其所具有的早期社会的文化意蕴,可认为“风”的本义是以容器(食器)又兼礼器的盘(槃)为基础而产生的具有两性关系及生殖方面文化意蕴的地方音乐。历代关于“风”义的说法诸如讽刺、风教、声调都是在本义基础上的引申义。“风”的本义对《诗经》中《风》诗文体的形成具有明显的作用:其一,通过“采诗”,“风”从“两性关系和生殖”的意义转变为“风教”的教化意义,进而形成《风》诗文体;其二,“风”的本义决定了《风》诗相较于《雅》《颂》在内容、功用及辞章结构上明显的文体区别。 展开更多
关键词 《诗经》 风本义 风教 文体
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六经皆治欲——中国古典学治欲的特点及展开
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作者 张昭炜 《武汉大学学报(哲学社会科学版)》 北大核心 2025年第1期97-110,共14页
六经是中国传统文化的核心经典,六经皆治欲:《尚书》与《春秋》治欲体现在为政之正;《诗经》治欲体现在思无邪与引导欲望的合理释放与适度满足;《周易》治欲是针对深隐欲望的几占以及损益配合等;《礼经》之礼与《乐经》之乐联动,具有进... 六经是中国传统文化的核心经典,六经皆治欲:《尚书》与《春秋》治欲体现在为政之正;《诗经》治欲体现在思无邪与引导欲望的合理释放与适度满足;《周易》治欲是针对深隐欲望的几占以及损益配合等;《礼经》之礼与《乐经》之乐联动,具有进与反之美。六经显示出中国古典学治欲资源的丰富,并且它们之间相互渗透,统一在各经皆礼、以礼治欲,表现为约束与温和释放欲望的对立统一。纵向展开,中国传统文化在前轴心时代、轴心时代、近世社会的治欲特点可表述为六经皆治欲、四书皆治欲、理学皆治欲,三者的发展既有连续性,亦各有时代特色。横向对比,中国古典学的六经治欲与禁欲主义、神秘主义对立,属于世俗化、人文化的治欲方案。伴随着全球世俗时代的到来,六经治欲的特色与优势愈加凸显。 展开更多
关键词 六经皆治欲 以礼治欲 四书皆治欲 欲望治疗 中国古典学
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基于CiteSpace的《道德经》英译研究综述及其生态展望
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作者 郭卫敬 《语言与文化研究》 2025年第1期182-185,共4页
本文运用CiteSpace可视化软件分析2010年至2023年发表于中国知网(CNKI)的《道德经》英译研究的期刊论文,绘制该研究领域的知识图谱以探索研究热点、前沿和趋势,并在此基础上展望《道德经》英译本的生态研究前景。研究结果显示,《道德经... 本文运用CiteSpace可视化软件分析2010年至2023年发表于中国知网(CNKI)的《道德经》英译研究的期刊论文,绘制该研究领域的知识图谱以探索研究热点、前沿和趋势,并在此基础上展望《道德经》英译本的生态研究前景。研究结果显示,《道德经》英译研究的视角日趋多元化,研究深度和广度都有所提高,但是《道德经》英译研究领域鲜少有学者探讨《道德经》的生态思想。《道德经》具有强烈的自然主义取向,被西方生态学者赞誉为“绿色经典”,因而《道德经》英译本的生态思想转译研究及生态话语分析研究具有较好的学术前景和现实意义。 展开更多
关键词 《道德经》 老子 英译研究 生态研究
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Analysis of fibronectin, fibronectin receptor and interleukin 1 in patients with cirrhosis treated by Yanggan Jieyu decoction 被引量:2
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作者 WU Hong, GAO Jie Sheng, FAN Jian Zhen, Huang Jing and DENG Jan Wei 《World Journal of Gastroenterology》 SCIE CAS CSCD 1997年第3期49-51,共3页
AIM To investigate the adjusting effects of the Yanggan Jieyu (YGJY, nourishing the liver and alleviate mental depression) decoction on the plasma concentration of fibronectin (FN), fibronectin receptor (FNR), tumor ... AIM To investigate the adjusting effects of the Yanggan Jieyu (YGJY, nourishing the liver and alleviate mental depression) decoction on the plasma concentration of fibronectin (FN), fibronectin receptor (FNR), tumor necrosis factor alpha (TNF α) and the activity of interleukin 1 (IL 1) in patients with cirrhosis. METHODS Thirty four cases of cirrhosis (in decompensation) were divided into YGJY decotion treated group and control group treated by routine method. FN, FNR and TNF α were measured with ELESA and expressed as mg/L (FN, FNR) and ng/L (TNF α), and IL 1 was measured by mice thymocyte proliferation using β scintillation counter and expressed as cpm. RESULTS In YGJY decoction treated group, before treatment, FN was 247 9±97 2, FNR 5 6±2 7, TNF α 83 9±7 1 and IL 1 was 2760 8±813 6, and after treatment. FN was 298 3±93 2 ( P <0 01), FNR 4 3±2 3 ( P <0 05, TNF α 93 6±12 0 ( P <0 05) and IL 1 was 1922 3±847 0 ( P <0 05). The FN and TNF α plasma level after treatment increased remarkably, while FNR and IL 1 decreased obviously. In the control group before treatment, FN was 248 8±101 9, FNR 5 5±1 9, TNF α 126 1±48 1 and IL 1 was 2540 6±603 2, and after treatment was 241 6±77 1 ( P >0 05), FNR 5 4±1 2 ( P >0 05), TNF α 100 6±15 5 ( P >0 05) and IL 1 was 2360 6±860 0 ( P >0 05), the plasma levels of FN, TNF α, FNR and IL 1 did not change signifiantly. CONCLUSION YGJY decoction could prevent the process of the hepatic fibrosis by readjusting the plasma levels of FN, FNR, TNF α and IL 1 mediating acivities in cirrhosis, which is of clinical significance. 展开更多
关键词 liver CIRRHOSIS Yan Gan jie Yu DECOCTION FIBRONECTIN receptors FIBRONECTIN tumor NECROSIS factor INTERLEUKIN 1 medicine Chinese traditional
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He Jie Tang in the treatment of chronic hepatitis B patients 被引量:5
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作者 Ze-Xiong Chen Shi-Jun Zhang +4 位作者 Shao-Xian Lao Hong-Tao Hu Cui-YiZhang Shi-He Guan Yan-Li Gu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第42期6638-6643,共6页
AIM: To explore the effect of He .lie Tang (decoction for medication) on serum levels of T lymphocyte subsets, NK cell activity and cytokines in chronic hepatitis B patients. METHODS: Eighty-five patients with chr... AIM: To explore the effect of He .lie Tang (decoction for medication) on serum levels of T lymphocyte subsets, NK cell activity and cytokines in chronic hepatitis B patients. METHODS: Eighty-five patients with chronic hepatitis B were divided randomly into two groups. Fifty patients in group I were treated with He .lie Tang (HIT) and 35 patients in group II were treated with combined medication. The levels of T-lymphocyte subsets (CD^3+, CD^4+, CD^8+), NK cell activity, cytokines (TNF-α, IL-8, sIL-2R) were observed before and after the treatment. Another 20 normal persons served as group 3. RESULTS: The level of CD^4+ cells and NK cell activity were lower, whereas the level of CD^8+ cells in patients was higher than that in normal persons (t = 2.685, 3.172, and 2.754 respectively; P〈0.01). The levels of TNF-α, IL-8, and sIL-2R in chronic hepatitis B patients were higher than those in normal persons (t = 3.526, 3.170, and 2.876 respectively; P〈0.01). After 6 months of treatment, ALT, AST, and TB levels in the two groups were obviously decreased (t = 3.421, 3.106, and 2.857 respectively; P〈0.01). The level of CD^4+ cells and NK cell activity were increased whereas the level of CD^8+ cells decreased (t = 2.179, 2.423, and 2.677 respectively; P〈0.05) in group I. The levels of TNF-α, IL-8, and sIL- 2R in group I were decreased significantly after the treatment (t = 2.611, 2.275, and 2.480 respectively; P〈0.05) but had no significant difference in groupII after the treatment (t = 1.906, 1.833, and 2.029 respectively; P〉0.05). The total effective rate had no significant difference between the two groups (X^2 = 2.882, P〉0.05) but the markedly effective rate was significantly different between the two groups (X^2 = 5.340, P〈0.05). CONCLUSION: HIT is effective in treating chronic hepatitis B. HIT seems to exert its effect by improving the cellular immune function and decreasing inflammatory cytokines in chronic hepatitis B patients. The function of HIT in protecting liver function in the process of eliminating virus needs to be further studied. 展开更多
关键词 He jie Tang Lymphocyte subsets NK cell CYTOKINES Chronic hepatitis B
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Mathematical model for flood routing in Jingjiang River and Dongting Lake network 被引量:6
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作者 Zuo-tao XIE Fang-li YANG Xiao-li FU 《Water Science and Engineering》 EI CAS 2012年第3期259-268,共10页
The main stream of the Yangtze River, Dongting Lake, and the river network in the Jingjiang reach of the Yangtze River constitute a complex water system. This paper develops a one-dimensional (l-D) mathematical mode... The main stream of the Yangtze River, Dongting Lake, and the river network in the Jingjiang reach of the Yangtze River constitute a complex water system. This paper develops a one-dimensional (l-D) mathematical model for flood routing in the river network Of the Jingjiang River and Dongting Lake using the explicit finite volume method. Based on observed data during the flood periods in 1996 and 1998, the model was calibrated and validated, and the results show that the model is effective and has high accuracy. In addition, the one-dimensional mathematical model for the river network and the horizontal two-dimensional (2-D) mathematical model for the Jingjiang flood diversion area were coupled to simulate the flood process in the Jingjiang River, Dongting Lake, and the Jingjiang flood diversion area. The calculated results of the coupled model are consistent with the practical processes. Meanwhile, the results show that the flood diversion has significant effects on the decrease of the peak water level at the Shashi and Chenjiawan hydrological stations near the flood diversion gates, and the effect is more obvious in the downstream than in the upstream. 展开更多
关键词 jingjiang River Dongting Lake jing/iang flood diversion area flood routing rivernetworks 1-D and 2-D coupled model
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联合信息环境JIE及其安全研究 被引量:8
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作者 李成 李明桂 向敏 《通信技术》 2015年第1期46-50,共5页
全球信息栅格(GIG)是美军为网络中心战建设的重要基础设施,而联合信息环境(JIE)是美军基于安全性考虑,对整个GIG重新设计而提出的,它将成为GIG的下一代战略储备。文中跟踪了JIE的研究进展,挖掘出美军提出JIE的深层原因,分析了JIE的特点... 全球信息栅格(GIG)是美军为网络中心战建设的重要基础设施,而联合信息环境(JIE)是美军基于安全性考虑,对整个GIG重新设计而提出的,它将成为GIG的下一代战略储备。文中跟踪了JIE的研究进展,挖掘出美军提出JIE的深层原因,分析了JIE的特点、关键建设领域、理想的终极状态。同时,对JIE的统一的安全体系结构和统一的身份和访问管理解决方案进行了剖析,文中最后全面深入地研究了JIE的安全功能。 展开更多
关键词 全球信息栅格 联合信息环境 安全体系结构
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Development Model of Rural Complex against the Backdrop of Rural Revitalization Strategy: A Case Study of "Baixianggu" in Jing’an County 被引量:1
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作者 Ying YU Zhiming WANG +1 位作者 Jiangnan HUANG Simin XIONG 《Asian Agricultural Research》 2020年第1期10-14,共5页
Rural complex is a new type of rural revitalization and development model,and fully mastering the concept and connotation of this model is of great significance to the construction of rural complex in our country.This... Rural complex is a new type of rural revitalization and development model,and fully mastering the concept and connotation of this model is of great significance to the construction of rural complex in our country.This paper makes an all-round research and discussion on the basic situation,development advantages,model characteristics and existing problems of the rural complex development model of Baixianggu in Jing’an County,and puts forward the corresponding optimization path in view of the existing problems of Baixianggu project,in order to provide scientific and objective reference basis for the construction of national rural complex. 展开更多
关键词 RURAL REVITALIZATION RURAL COMPLEX Baixianggu jing’an COUNTY
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A Comparative Study of Two Spanish Versions of the Poem Junzi Xielao of Shi Jing 被引量:1
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作者 WU Qian 《Journal of Literature and Art Studies》 2019年第2期175-182,共8页
The purpose of this paper is to do a comparative study of two complete Spanish versions of Shi Jing with a detailed analysis of the poem Junzi Xielao.The culture and personal backgrounds of the two translators,their t... The purpose of this paper is to do a comparative study of two complete Spanish versions of Shi Jing with a detailed analysis of the poem Junzi Xielao.The culture and personal backgrounds of the two translators,their translation purposes and intended readers largely influenced the translating style and technique of the two versions. 展开更多
关键词 SHI jing SPANISH TRANSLATION TRADITIONAL Chinese culture extratextual factors
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Compound Chai Jin Jie Yu Tablets,Acts as An Antidepressant by Promoting Synaptic Function in the Hippocampal Neurons 被引量:6
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作者 LI Zi-Rong HAN Yuan-Shan +4 位作者 WU Meng-Yao LIU Jian JIN Shi ZHANG Xi WANG Yu-Hong 《Digital Chinese Medicine》 2020年第2期80-95,共16页
Objective To investigate the effectiveness of compound Chai Jin Jie Yu Tablets(CJJYT)in ameliorating cognitive impairment associated with depression and its potential mechanism of action.Methods In vitro experiments,t... Objective To investigate the effectiveness of compound Chai Jin Jie Yu Tablets(CJJYT)in ameliorating cognitive impairment associated with depression and its potential mechanism of action.Methods In vitro experiments,the hippocampus was isolated from the whole brain of the fetal rat and cultured into hippocampal neuron cells.50μM corticosterone(CORT)was added to each group 18 h before the experiment for modeling depression,with the exception of the control group.After modeling,the blank serum group was added with 10%blank serum,the CJJYT group and the venlafaxine group were added with the corresponding 10%drug-containing serum,and the control group and the model group were added with equal volumes of culture medium.The intracellular Ca^2+mean fluorescence intensity,miniature excitatory postsynaptic current(mEPSC)current amplitude,and frequency of different hippocampal neurons were evaluated as indicators of synaptic function in the hippocampal neurons.In addition,the expression of synaptic plasticity related proteins,synaptophysin-α(SYN-α),N-methyl-D-aspartate receptor 2A(NR2A),N-methyl-Daspartate receptor 2B(NR2B),post synaptic density 95 protein(PSD-95),calcium/calmodulin dependent protein kinaseⅡ(CaMKⅡ)and synaptic associated protein(SynGAP)were detected in the hippocampal neurons by immunofluorescence staining and high content analysis(HCA)system.Then,reverse transcription-polymerase chain reaction(RT-PCR)was used to detect the mRNA expression levels of SYN-α,NR2A,NR2B,PSD-95,CaMKⅡand SynGAP.For in vivo experiments,except for those in the blank control group,all rats were treated within a single cage for chronic unpredictable stress-induced depression modeling and subjected to corresponding drug interventions.Behavioral tests were used to detect depressive behavior and determine learning,memory and other cognitive abilities,whereas enzyme-linked immunosorbent assay(ELISA)was used to detect the CORT levels.Golgi-Cox staining was used to observe changes in the synaptic morphology of parahippocampal gyrus CA1 area(CA1)and dentategyrus(DG).Results In vitro,CJJYT treatment reduced the intracellular Ca^2+mean flurorescence intensity in the hippocampal neurons(P<0.05),causing a reduction in the frequency and current amplitude of mEPSC(P<0.05),and thus inhibited the excessive activation of post-synaptic receptors.CJJYT treatment reduced the protein and mRNA expression of SYN-α,NR2A,NR2B and PSD-95 in the hippocampal neurons(P<0.05),increased the mRNA and protein expression of CaMKⅡand SynGAP(P<0.05),and thereby improved the synaptic plasticity of the hippocampal neurons.In vivo,CJJYT intervention improved sucrose preference,voluntary activity,learning and memory ability of Morris water maze test,and suppressed appetite(P<0.05),and increased the despair feeling of forced swimming test(P<0.05).The CORT level was reduced(P<0.05),leading to the repair of synaptic damage in the hippocampal neurons.Conclusions CJJYT can improve the synaptic function of hippocampal neurons and has obvious protective effects on neurons.It can repair the structural damage in the hippocampal neurons,improving the cognitive ability of the depressed model rats.The mechanism of CJJYT improving cognition in depressed rats may be related to the transmission and function of SYN-α/NR and its downstream neurotransmitters. 展开更多
关键词 Compound Chai Jin jie Yu Tablets(CJJYT) Depression SYN-α/NR Synaptic plasticity Cognition
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Yi Qi Jie Du Formula and Salinomycin Combination Treatment Mediates Nasopharyngeal Carcinoma Stem Cell Proliferation,Migration and Apoptosis via CD44/Ras Signaling Pathway 被引量:7
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作者 HE Lan ZHOU Fang-Liang +5 位作者 ZOU Pan WANG Xian-Wen JIANG Yi-Lan HE Ying-Chun LIAO Duan-Fang CAO De-Liang 《Digital Chinese Medicine》 2020年第4期297-308,共12页
Objective To assess the effects of Yi Qi Jie Du Formula(YQJDF)combined with salinomycin(SAL)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying molecular mechanisms.Methods Cell counting meth... Objective To assess the effects of Yi Qi Jie Du Formula(YQJDF)combined with salinomycin(SAL)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying molecular mechanisms.Methods Cell counting methods,the CCK-8 assay,transwell migration assay and JC-1 staining,were used to observe the effects of the combination on the proliferation,migration and apoptosis of NPC stem cells,respectively.Western blot was used to detect the levels of protein in NPC-SCs.Results YQJDF combined with SAL had a synergistic effect on the inhibition of proliferation and migration and induction of NPCSC apoptosis.Mechanistically,YQJDF combined with SAL synergistically upregulated the levels of apoptotic proteins,including cleaved Caspase-3,cleaved Caspase-7 and cleaved Caspase-9.Moreover,YQJDF combined with SAL synergistically decreased the levels of CD44,p-c-Src,Ras,p-PKCδ,p-MEK,p-c-Raf,p-ERK1/2 and p-AKT proteins.Conclusions The combination of YQJDF and SAL has a synergistic effect on the inhibition of NPC-SC proliferation and migration and induction of apoptosis,which may be closely related to the downregulation of the CD44/Ras signaling pathway. 展开更多
关键词 Yi Qi jie Du Formula(YQJDF) SALINOMYCIN Nasopharyngeal carcinoma stem cells (NPC-SCs) PROLIFERATION Apoptosis CD44/Ras signaling pathway
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Yi Qi Jie Du Decoction Inhibits Proliferation and Induces Apoptosis of Nasopharyngeal Carcinoma Stem Cells Through Mitochondrial Apoptosis Pathway 被引量:5
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作者 ZHOU Fang-Liang HE Lan +4 位作者 HE Dan WANG Xian-Wen SHI Hong-Jian HE Ying-Chun CAO De-Liang 《Digital Chinese Medicine》 2019年第4期219-226,共8页
Objective To assess the effects of Yi Qi Jie Du Decoction(YQJDD)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying mechanism.Methods NPC-SCs were collected in serum-free culture system and i... Objective To assess the effects of Yi Qi Jie Du Decoction(YQJDD)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying mechanism.Methods NPC-SCs were collected in serum-free culture system and identified by the sphere formation assay.The effect of YQJDD on the proliferation of NPC-SCs was detected using the Cell Counting Kit-8 assay.The change of mitochondrial membrane potential(ΔΨm)in NPC-SCs following treatment with YQJDD was investigated by JC-1 staining.The levels of apoptosisassociated proteins were examined using western blot analysis.Results YQJDD significantly inhibited the proliferation of NPCSCs in dose-and time-dependent manners.JC-1 staining revealed that YQJDD lowered theΔΨm of NPC-SCs in a timedependent manner.After treatment with YQJDD,the expression of cleaved caspase-3,-7 and-9,cleaved poly-ADP ribose polymerase,P21 and P53 were increased,while the expression of Survivin in NPC-SCs was decreased.However,the expression of cleaved caspase-8 remained nearly unchanged.Conclusions YQJDD inhibits the growth and induces apoptosis of NPC-SCs via an intrinsic apoptosis pathway. 展开更多
关键词 Nasopharyngeal carcinoma(NPC) Yi Qi jie Du Decoction(YQJDD) APOPTOSIS Cancer stem cells Mitochondrial apoptosis pathway
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