Inflammatory bowel disease course in Crohn's disease:Is the natural history changing?

Crohn’s disease (CD) is a multifactorial potentially debilitating disease. It has a variable disease course, but the majority of patients eventually develop penetrating or stricturing complications leading to repeated surgeries and disability. Studies on the natural history of CD provide invaluable data on its course and clinical predictors, and may help to identify patient subsets based on clinical phenotype. Most data are available from referral centers, however these outcomes may be different from those in population-based cohorts. New data suggest the possibility of a change in the natural history in Crohn’s disease, with an increasing percentage of patients diagnosed with inflammatory disease behavior. Hospitalization rates remain high, while surgery rates seem to have decreased in the last decade. In addition, mortality rates still exceed that of the general population. The impact of changes in treatment strategy, including increased, earlier use of immunosuppressives, biological therapy, and patient monitoring on the natural history of the disease are still conflictive. In this review article, the authors summarize the available evidence on the natural history, current trends, and predictive factors for evaluating the disease course of CD.

Bearing in Mind History, Setting the Right Course and Creating the Future for China-US Relations

Four decades after the two countries established diplomatic ties, China-US relations have once again arrived at a crossroads. A China that adheres to the path of peace, cooperation and openness is an opportunity for rather than a threat to the US; and a China that plays a constructive role in the international arena is a partner rather than an opponent of the US.

Incorporating Ideological and Political Teaching Methods into the Course of Mongolian Medicine History

School education shoulders the great mission of cultivating people by virtue,and has an unshirkable responsibility in students ideological and political education.In addition to the main channel of ideological and political theory courses,it is also necessary to make ideological and political education permeate other professional courses,so as to realize moral education.The integration of Mongolian Medicine History and ideological and political education has unique advantages in terms of content and scientific attributes.However,when the two are organically integrated,it is an important step to successfully carry out ideological and political theories teaching in the course by choosing suitable cases,digging out the ideological and political meaning behind each case,and finally exerting a subtle influence on students thoughts.

Crucial steps in the natural history of inflammatory bowel disease

Inflammatory bowel diseases(IBD),including ulcerative colitis(UC) and Crohn's disease(CD),are chronic,progressive and disabling disorders.Over the last few decades,new therapeutic approaches have been introduced which have led not only to a reduction in the mortality rate but also offered the possibility of a favorable modification in the natural history of IBD.The identification of clinical,genetic and serological prognostic factors has permitted a better stratification of the disease,thus allowing the opportunity to indicate the most appropriate therapy.Early treatment with immunosuppressive drugs and biologics has offered the opportunity to change,at least in the short term,the course of the disease by reducing,in a subset of patients with IBD,hospitalization and the need for surgery.In this review,the crucial steps in the natural history of both UC and CD will be discussed,as well as the factors that may change their clinical course.The methodological requirements for high quality studies on the course and prognosis of IBD,the true impact of environmental and dietary factors on the clinical course of IBD,the clinical,serological and genetic predictors of the IBD course(in particular,which of these are rel-evant and appropriate for use in clinical practice),the impact of the various forms of medical treatment on the IBD complication rate,the role of surgery for IBD in the biologic era,the true magnitude of risk of colorectal cancer associated with IBD,as well as the mortality rate related to IBD will be stressed;all topics that are extensively discussed in separate reviews included in this issue of World Journal of Gastroenterology.

Discussion on the Integration of Musical Elements into the Social Practice Teaching of “The Outline of Chinese Modern and Contemporary History”

Teachers of the ideological and political theory course should be confident in the ideological and political course,insist on the unity of explicit education and recessive education,be good at exploring the ideological and political education resources contained in other courses and teaching methods,and realize the full-time education of all employees.At present,there is still much room for improvement in the collaborative education of aesthetic education and moral education.Teachers of the ideological and political theory course should actively guide and explore the ideological and political education resources of music resources,and use the artistic discourse system to interpret the historical process of modern Chinese social development and revolution,construction,and reform,and its inherent regularity,which reflects the national history and national conditions,reflects the positive results of Marxism in China,the era,and the popularization,guiding students to profoundly understand the history and how the people chose Marxism,chose the Chinese Communist Party,chose the socialist road,and chose reform and opening up;strengthening the road self-confidence,theoretical self-confidence,institutional self-confidence,and cultural self-confidence of socialism with Chinese characteristics;earnestly establish the belief that“only socialism can save China,only socialism with Chinese characteristics can develop China.”

The Centenary of the CPC: Leading the Times by Grasping the Laws and Trends of Historical Development

Discussions on grasping the laws and trends of historical development take a fundamental theoretical position in the scientific system of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era.Xi Jinping’s important statements have systematically answered such questions as what type of laws and trends of historical development should be followed,how did the Party follow the laws and trends of historical development in its centennial history,and how should the laws and trends of historical development be followed in a new era.The birth of the Communist Party of China(CPC),the victory of China’s War of Resistance against Japanese Aggression,the founding of the People’s Republic of China,and the unveiling of a new era for reform and opening up and socialism with Chinese characteristics are all the results of grasping the laws and trends of historical development.Over the past century,the Party has followed the laws and trends of historical development and continuously advanced the sinicization of Marxism on the basis of adhering to the unification between truth and values.In pursuit of“putting people first,”the Party has courageously been reforming itself and made relentless progress in the great endeavor of Party building.History shows that a keen appreciation of the laws and trends of historical development is an important sign of political maturity for a proletarian party.Only by applying Marxism according to current times and conditions will we keep abreast with the laws and trends of historical development.We should establish a broader concept of history and identify the laws and trends of historical development from the interactions and linkages between China and the rest of the world.We must recognize and promote the outstanding role of great leaders in steering the country in line with the laws and trends of historical development.

On the Historical Change and Enlightenment of the Curriculum System of Physical Education Major in China

The course of the modernization of Chinese sports specialty is also the process of the emergence and development of sportseducation. This historical process has initially formed its own characteristics and completed the task of a period quickly, which cantrigger our reflection on sports education. Under the influence of the continual development of educational curriculum reform, neweducational reform ideas and policies are constantly put forward. The reform of sports specialty must be a combination ofworldwide and national characteristics. Society, students and knowledge are external factors to promote the reform of SportsSpecialty in order to meet the requirements of the development of the new century. Under the guidance of "health first" andstudent-centered school physical education ideology, the reform process of physical education specialty is accelerating andshowing a deep development trend. This paper systematically combs the process of the development and evolution of thecurriculum of modern sports majors in China, analyzes the characteristics of historical sports majors, summarizes the regularhistorical experience of the development of sports majors, and aims to provide useful benefits for the current reform of sportsmajors in China Revelation.

高校图书馆党史学习教育基地建设理路——以京津冀15家“双一流”高校图书馆为例

文章探讨高校图书馆党史学习教育基地建设的历史之源、理论之据和价值之蕴,调研京津冀15家“双一流”高校图书馆党史学习教育开展情况,总结分析其发展现状及存在的问题,并提出高校图书馆党史学习教育基地建设路径,即强化党史学习教育资源建设,设立沉浸式党史学习专区,借助新技术赋能智慧党建,融入师生话语体系打造品牌活动,提升红色资源影响力和传播力。

新时代加强大学生中共党史教育“时度效”的要求、问题与路径

“时度效”是检验中共党史教育成效的重要指标。新时代加强大学生中共党史教育“时度效”需要遵循坚持党性与时代性相统一、思想性与科学性相融合、精准性与有效性相结合等基本要求。从“时度效”视角透视新时代部分大学生中共党史教育问题,主要体现在“时”的掌握不准、“度”的把握不足、“效”的实现不佳三个方面,亟需以“育以因时”为基本点、以“育以适度”为关节点、以“育以有效”为落脚点,着力从更新教育理念内容、创新教育方式方法、提升党史育人质量三个层面协同推进、共同发力,以助力于新时代大学生中共党史教育提质增效。

中国共产党领导百年农业现代化的历程、特征与经验

农业现代化是中国式现代化的重要组成部分,是建设中国特色社会主义强国的关键支撑。中国共产党自成立以来,便领导全国人民进行了漫长而曲折的现代化建设探索,并取得了中国特色农业现代化实践的历史性的成就。本研究基于对党领导下我国百年农业现代化历史进程的梳理,系统归纳其在目标指向、施策逻辑和实现路径上的演进特征,并从“目标遵循、思想底色、关键推力、基本方法、路径策略、价值旨归”等六个维度,总结出以坚持“人民至上、自信自立、守正创新、问题导向、系统推进、胸怀天下”等为核心的基本经验,旨在为新时代中国式农业现代化的持续深入推进提供价值参考。

以伟大建党精神创新高校思政课的三重视角——以“马克思主义基本原理”课教学为例

伟大建党精神为高校思想政治理论课教学创新提供了丰富的育人资源,为“马克思主义基本原理”课教学改革提供了崭新的实践视角。基于此,从教学内容、教学方法和教学途径三个视角,探究伟大建党精神全面融入高校“马克思主义基本原理”课教学的实践模式,借助伟大建党精神推进“马克思主义基本原理”课教学内容和形式的改革创新,借助“马克思主义基本原理”课教学讲授和弘扬伟大建党精神。融入伟大建党精神的科学内涵和鲜明特征,深化“马克思主义基本原理”课教学的育人内容。发挥伟大建党精神的育人功能和铸魂作用,提高“马克思主义基本原理”课教学的育人效果。赓续伟大建党精神的红色基因和精神品格,拓宽“马克思主义基本原理”课教学的育人路径。充分汇聚“马克思主义基本原理”课与伟大建党精神的育人合力,着力培育能够坚守理想、担当使命、英勇斗争、不负人民的新时代大学生,大力提升“马克思主义基本原理”课教学的育人成效。

人类文明新形态融入高校思政课的学理阐释与实践要求

人类文明新形态是中国特色社会主义实践取得的重大文明成就和理论创新成果,科学印证了马克思、恩格斯关于人类文明形态的演进逻辑。高校思政课是开展系统马克思主义理论教育的重要阵地,推动人类文明新形态融入高校思政课,需要厘清人类文明新形态融入高校思政课的内生动力、时代价值、现实依据和实践要求。人类文明新形态融入高校思政课教学实践,能够引导大学生明确自身的历史使命和责任担当,形成学习和践行人类文明新形态的思想自觉和行动自觉,为实现中华民族伟大复兴的中国梦砥砺前行。

新民主主义革命以来知识分子工作的政策变迁及启示

新民主主义革命时期以来,中国共产党不断调整优化完善重视知识分子工作政策,通过做好知识分子工作,最大限度地将其凝聚于党的周围,为实现各个历史时期的任务和目标,为实现中华民族伟大复兴凝心聚力。在工作实践中,形成了坚持党管人才原则,加强知识分子管理以及加强党外知识分子系统教育培养等基本经验。新时代做好知识分子工作,一要高度重视知识分子工作,把知识分子工作作为一项基础性、战略性工作来抓;二要充分发挥统一战线制度优势和效能,聚天下英才而用之;三要贯彻落实知识分子工作的基本政策,激发广大党外知识分子的智慧和力量。

以党建引领“一体两翼”儿科学思政体系的构建

医学院校肩负着培养医德高尚、甘于奉献、勇于担当的高素质医疗人才的重任。做到课程承载思政,使各类课程与思政课程同向同行,形成协调效应是各医学院校的重要目标。本研究旨在将党建与医学生的实践教学相结合,创新党建活动,充分挖掘思政元素,提炼为社会主义核心价值观、医德医风及人文素养、法治教育和科学思维4个重点,依托讲授故事、教学查房、案例分析、情景再现等灵活多样的教学方法,探索多维路径。以党建引领“一体两翼”的儿科思政体系的构建,提升实习生的综合素质。

伟大建党精神融入高校思想政治理论课的实施困境探析

伟大建党精神教育是落实立德树人、实现为党育人的重要要求,也是高校思政课教学的内在要求。但在伟大建党精神融入高校思政课时面临意识不足、内容单一、方法老套等问题。从问题成因看,这些融入问题不仅与伟大建党精神资源开发不够、资源共享程度不高等有关,也与伟大建党精神与市场经济环境之间兼容性差、高校思政课教学缺乏情感性和创新性等有关。为此,应以伟大建党精神与思政课教学融合缺失为切入点,优化高校思政课的教学理念、课程内容、方法手段等,实现两者的无缝衔接和有机融合。

坚持严密党的组织体系的逻辑理路与经验启示

坚持严密党的组织体系是中国共产党“治国必先治党,党兴才能国强”的必然要求,也是我们党强化组织建设,深入推进党的伟大自我革命的有效举措.党的力量源于组织.新形势下,面对世界百年未有之大变局,面对全面建设社会主义现代化强国、以中国式现代化全面推进中华民族伟大复兴的崇高使命,必须坚持正确政治路线,坚持做到“三个统一”,坚持守正创新,坚持使命引领和问题导向,坚持系统观念,进一步严密党的组织体系与加强党的全面领导,切实增强党组织政治功能和组织功能,建设强大政党,才能确保百年大党始终成为中国特色社会主义事业的坚强领导核心.

中国共产党领导卫生防疫事业的百年历程、基本特点和经验启示

中国共产党自成立之初,就将保障人民健康同争取民族独立、人民解放的事业紧密联系,高度重视国内卫生防疫事业发展工作。中国共产党领导下的百年卫生防疫事业经历初创、拓展、完善与跨越式发展四大时期,取得历史性进展与成效,形成凸显防疫工作政治价值、遵循人民至上价值准则、坚持依法防控重要原则、落实群防群控防疫机制的基本特点。在百年卫生防疫实践中,中国共产党积累了丰富的经验,历史经验表明,坚持党在防疫工作中的领导地位是做好卫生防疫工作的根本保证,坚持科学防治是战胜疫情的最有力武器,坚持群众路线是推动卫生防疫事业不断前进的基本凭藉。

《中国共产党简史》直接引语英译形式的语用分析

《中国共产党简史》及其英译本为中外读者解读中国共产党提供了权威读本。直接引语是该著作主要话语表达方式之一,对中共党史对外交流具有积极意义。基于自建汉英平行语料库,发现《中国共产党简史》中直接引语形式与其英译形式并非完全对应,译文形式更为灵活。进一步对比分析表明,这些英译形式反映出译者立足“讲好中国故事”的交际意图,积极与语言语境、交际语境和译文读者互动而进行语用顺应,有助于中国共产党故事的对外翻译,也为中国故事的国际传播提供了宝贵经验。

党的二十大精神融入中国音乐史课程思政的研究与实践

中国音乐史课程蕴含丰富的课程思政元素,是音乐专业课程思政建设的重要阵地。在党的二十大精神引领下,可以深入挖掘、有效整合课程内容,确立与中国音乐三大发展阶段相对应的6个思政主题、25项思政案例和思政点,构建线索鲜明、专题突出、案例典型的“音乐+历史+现实+思政”四位一体育人体系。在课程改革中进一步探索数字赋能教学新模式,并以“思政+通识”为目标,在“三全育人”格局下打造高质量中国音乐史公共选修课和线上慕课,对音乐课程思政推进和数字化革新等具有探索、借鉴价值。