随着集群技术的普及,集群系统如何对外提供服务成为十分重要的课题。Phoenix是一体化、高可靠、高可扩展的集群操作系统。PWP(Phoenix Web Portal)位于Phoenix系统的最上层,旨在为各类用户访问Phoenix系统提供一站式的服务。该文介绍了...随着集群技术的普及,集群系统如何对外提供服务成为十分重要的课题。Phoenix是一体化、高可靠、高可扩展的集群操作系统。PWP(Phoenix Web Portal)位于Phoenix系统的最上层,旨在为各类用户访问Phoenix系统提供一站式的服务。该文介绍了PWP的设计与实现。展开更多
Based on the measured data, suspended sediment concentration, surface sediment grain size, current and waves, the sediment transport mechanisms and pathways in the Phoenix Island area were analyzed using methods of fl...Based on the measured data, suspended sediment concentration, surface sediment grain size, current and waves, the sediment transport mechanisms and pathways in the Phoenix Island area were analyzed using methods of flux decomposition and Grain Size Trend Analysis(GSTA). The results show that net suspended sediment is mainly transported by average current, Stokes drift, and gravitational circulation. The transport direction of suspended sediment is varying and basically following the direction of residual tidal currents. Surface sediment transport pathways are primarily parallel to the coastline along with two convergent centers. Waves and longshore currents have a significant influence on sediment transport, but the influence is limited due to a steep and deep underwater bank. Tidal current is the main controlling factor for sediment transport, especially in the deep water area. Neither suspended nor surface sediment is transported towards the southwest. The South Shandong Coastal Current(SSCC) has little effect on sediment transport processes in the nearshore area of Phoenix Island.展开更多
Objective: To investigate different types of dates and medical properties of influencing blood clotting and wound healing in an animal model. Methods: Three different cultivars of dates(Ajwa, Khalas, and Fardh) were e...Objective: To investigate different types of dates and medical properties of influencing blood clotting and wound healing in an animal model. Methods: Three different cultivars of dates(Ajwa, Khalas, and Fardh) were examined in-vivo, for blood clotting and wound healing using CD1 mice of both sexes. Study of toxicity to animals was performed accordingly prior to further investigations. The ethanolic extracts were given orally to animals as a constituent in their daily water. Blood samples were obtained from the mice inferior vena cava to carry out the prothrombin time(PT) assay using the manual method and confirmed using a semi-automated machine. The bleeding time(BT) assay was performed using the cutting technique. In the wound healing analysis, a small cut(5-10 mm) in the skin overlying the thigh was conducted in all mice under anesthesia. The diameter of the cut and healing status were measured on a daily basis throughout the time of the experiment using a roller. Results: Ajwa was able to elevate both PT and BT(P<0.05), significantly in a time-dependent manner followed by Khalas date(P<0.05). The results of PT and BT of Fardh date were found to be very close to those of the control group(P<0.05). Despite its activity as an anticoagulant, Khalas date showed a potential property to enhance wound healing in contrast to other dates and the control groups in this study. Conclusions: Omani Khalas date fruit has both antithrombotic as well as wound healing properties. The results open a new gate with these fruits for exploring the potential component(s) that may play an important role in antithrombotic as well as wound healing process.展开更多
Background: Dopamine has been known to facilitate male sexual function. Methods: The effect of aqueous extract (140 mg/kg) of Phoenix dactylifera date palm pollen on sexual behavior and determining of dopamine transmi...Background: Dopamine has been known to facilitate male sexual function. Methods: The effect of aqueous extract (140 mg/kg) of Phoenix dactylifera date palm pollen on sexual behavior and determining of dopamine transmission in the nucleus accumbens was studied in male rats using in vivo microdialysis. Results: Releasing of dopamine increased significantly in the nucleus accumbens when a receptive female was introduced behind a screen (p 0.001). During copulation, dopamine increased markedly in control and treated rats. Phoenix dactylifera Date Palm Pollen enhanced the orientation of males towards females by increasing mounting and ano-genital investigatory behavior. Improving of sexual behavior and dopamine release was higher in treated rats in comparison with control (p 0.001). Conclusion: These results indicate a neurochemical basis for interaction between dopaminergic agents and male sexual behavior. Therefore, Phoenix dactylifera Date Palm Pollen seems to act as a dopamine agonist and to cure male infertility. It can be used as an aphrodisiac that leads to further increases in dopamine release.展开更多
Aim of study: Ancient literature alluded to the use of a number of plants/preparations as sex enhancer. One of such botanicals is Phoenix dactylifera in which the pollen grain has been acclaimed to be used as an aphro...Aim of study: Ancient literature alluded to the use of a number of plants/preparations as sex enhancer. One of such botanicals is Phoenix dactylifera in which the pollen grain has been acclaimed to be used as an aphrodisiac. However, the validity has not been scientifically tested. Dopamine is known to facilitate male sexual function. Therefore, the present study was undertaken to evaluate the effect of aqueous extract of Phoenix dactylifera pollen on the sexual behavior of male rats and to measure of serum Estradiol and Testostrone. Also, dopamine transmission in the nucleus accumbence (NAc) was studied in male rats using in vivo microdialysis. Methods and Materials: sixty male rats were randomized into 6 groups (A-F). Group A received 0.2 ml of Normal Saline mixed with Dimethyl Sulphate (DMSO), while groups B-F were injected same volume containing 35 mg/kg, 70 mg/kg, 105 mg/kg, 140 mg/kg and 350 mg/kg of DPP extract, respectively. Sexual behavioral parameters including mounting, intromission and ejaculation frequencies and latencies were recorded in male rats one hour after injection of extract by mating with a receptive female (1:1). The male serum testosterone and estradiol concentrations were also determined. Results: All doses stimulated male sexual behavior. Extract significantly increased mount, ejaculation, intromission frequencies and ejaculation latency in comparison to controlled ones (p 0.001). Mount and intromission latencies significantly reduced (p 0.001). Maximum effect was observed in dose 140 mg/kg. This extract was found to enhance Testestrone, Estradiol and the orientation of males toward female ones by increasing mounting and ano-genital investigatory behavior. Conclusions: Data from this study identified that the aqueous extract of Phoenix dactylifera pollen grain enhanced sexual behaviour in male rats. The improved sexual appetitive behaviour in male rats may be attributed, to the alkaloids, saponins, and or flavonoids since these phytochemicals has engorgement, androgen enhancing. Also, our findings support the traditional use of this plant as acclaimed aphrodisiac and for the treatment of pre-ejaculation and impotency.展开更多
Phoenix, a very beautiful and popular image in China,like dragon, is an imagined and legendary animal existing only in people's mind. It is such an important component of Chinese culture that we can see a sort of ...Phoenix, a very beautiful and popular image in China,like dragon, is an imagined and legendary animal existing only in people's mind. It is such an important component of Chinese culture that we can see a sort of phenomenon called phoenix phenomenon comes into being in Chinese culture, which deserves efforts to elaborate and whose origin is worth probing. As the totem worshipped by the ancient Chu people, phoenix also displays the basic features of Chinese culture: integratedness and inclusiveness.展开更多
Objective:To evaluate and compare the antioxidant activity,total phenolic contents(TPCs) and in vitro antidiabetic activity of various pits extracts obtained from five Omani date cultivars.Methods:Sun-dried mature fru...Objective:To evaluate and compare the antioxidant activity,total phenolic contents(TPCs) and in vitro antidiabetic activity of various pits extracts obtained from five Omani date cultivars.Methods:Sun-dried mature fruits of five Omani date varieties,namely,Fardh,Naghal,Khalas,Khinazi and Khasab were purchased from the local market in Muscat,Oman in the month of September 2014.Four seed extracts viz.water,ethanol,methanol and acetone were prepared for each date variety and their antioxidant activities were investigated by 1,1-diphenyl-2-picrylhydrazyl,hydrogen peroxide scavenging method and reducing power assay method,respectively.In vitro antidiabetic activity of the date pit extracts was evaluated by measuring their inhibitory effect on a-glucosidase and aamylase level.TPCs were also quantified colorimetrically.Results:The results indicated that TPC of date seeds was solvent dependent.Acetone,ethanol and methanol were found to be significantly better solvents than water in extracting phenolic compounds from the date seeds.Pit extracts exhibited moderate to good in vitro antioxidant activity and increased reducing power.Among all date pit extracts,water extract exhibited significant in vitro antidiabetic activity in comparison to standard drug,acarbose.Conclusions:The present study confirms that disposed waste of Omani dates is a rich source of dietary antioxidant because of its high TPC.The pits due to their inhibitory effects on a-glucosidase and a-amylase level could be used as a monotherapy along with an appropriate diabetic diet and exercise or might be in conjunction with antidiabetic therapy to manage and prevent progression of diabetes.展开更多
Our overall knowledge of the medicinal uses of plants suggests that natural compounds could be useful in the treatment of cutaneous fungal infections in tropical regions. Furthermore, the possibilities of treatment us...Our overall knowledge of the medicinal uses of plants suggests that natural compounds could be useful in the treatment of cutaneous fungal infections in tropical regions. Furthermore, the possibilities of treatment using plant extracts may be even broader than is already known when one considers plants that have not been extensively studied in this context, such as the regional species Phoenix dactylifera and Ziziphus spina-christi. This study compared the antimicrobial activity of Phoenix dactylifera and Ziziphus spina-christi extracts in terms of their biochemical and molecular effects on Candida albicans (ATCC CA 10231). These effects included altered levels of intracellular sterols, changes in the permeability of the cell membrane, and changes in the TEF1: QRTTEF1, CaERG1: ERG1, CdERG12: CdERG1, and ERG25: ERG25 genes. Scanning electron microscopy (SEM) was used to identify morphological characteristics, and energy-dispersive X-ray spectroscopy (EDAX) analyses were conducted. In treated samples, the SEM and EDAX analyses showed cell cavities and shrinkage of the cell wall, and the number of cells was reduced to only a few abnormal cells as compared with that in the untreated samples. Yttrium was detected in the cells treated with Z. spina-christi, and high levels of osmium were detected in the cells treated with P. dactylifera. Compared with control cells, cells exposed to the concentration 150 μl/ml of Z. spina-christi extract had an average sterol concentration that was nearly 3 times higher, while the concentration was 5.5 times higher for cells treated with the 150 μl/ml of P. dactylifera extract. The ethanol extracts affected the permeability of C. albicans cell membrane. Gene sequencing showed gaps and mismatches in the ERG1, ERG12, and ERG25 genes after treatment with P. dactylifera and Z. spina-christi extracts compared with that in the controls. The results were highly significant (p ≤ 0.01). We conclude that the ethanol extracts of P. dactylifera and Z. spina-christi have antimicrobial activity through several mechanisms in the yeast cell.展开更多
The potential of the Senegal date palm (</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"&g...The potential of the Senegal date palm (</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span><span><i><span style="font-family:""><span style="font-family:Verdana;">Phoenix </span><span style="font-family:Verdana;">reclinata</span></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"></i></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) seed bio-char to remove chromium (VI) ions from aqueous solutions by adsorption was investigated. Adsorption experiments were performed on the tannery effluent and standard aqueous solutions of chromium (VI) for varying adsorbent doses, contact times, pH, temperatures, and interfering anionic ions by batch mode. </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span><span><i><span style="font-family:""><span style="font-family:Verdana;">Phoenix </span><span style="font-family:Verdana;">reclinata</span></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"></i></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> seeds (PRS) bio-char was used in the investigation and the residual chromium (VI) was determined using the atomic absorption spectrophotometer (AAS). Results showed that the bio-char removed up to 86% of chromium (VI) ions in the effluent at pH 2. The highest percentage adsorption registered was 97% in an aqueous solution of chromium (VI) at pH 1 and this dropped to less than 10% at pH greater than 2. A general increase in adsorption with</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> the</span></span></span><span><span><span style="font-family:""> <span style="font-family:Verdana;">increase</span><span style="font-family:Verdana;"> in temperature was observed but reduced when the temperature was raised beyond 60</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">°</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">C. The presence of interfering anions caused a reduction in the adsorption of chromium (VI) ions. The adsorption process fitted both Langmuir and Freundlich adsorption models and the maximum adsorption capacity, </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span><span><i><span style="font-family:""><span style="font-family:Verdana;">Q</span><sub><span style="font-family:Verdana;">o</span></sub></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><sub><span style="font-family:Verdana;"></i></span></sub></i></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">, was 0.6593 mg/g. Thus, PRS bio-char can </span><span style="font-family:Verdana;">therefore</span><span style="font-family:Verdana;"> be used by industries and institutions like secondary schools to treat effluents that contain chromium (VI).展开更多
Background: The synergistic mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera (STCD) aqueous extract is a common drink in Port Harcourt, Nigeria. It is assumed to have various health benefits. Howe...Background: The synergistic mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera (STCD) aqueous extract is a common drink in Port Harcourt, Nigeria. It is assumed to have various health benefits. However, the synergistic mixture of the content has not been studied scientifically, hence the need to evaluate its effect on the liver and kidney being part of the body’s metabolic organs. Aim: This study evaluated the synergistic mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera (STCD) aqueous extract in male albino rats. Methods: Acute toxicity LD<sub>50</sub> of STCD was carried out, afterwards, fifteen male albino rats were grouped into three groups with 5 rats in each group;Control, 200 mg/kg, 400 mg/kg STCD. The rats were administered STCD orally 24 hourly, for 21 days, with feed and water ad libitum. At the end of the experiment, blood samples were collected for biochemical analysis of the liver and kidney biomarkers, while the liver and kidney tissues were harvested for histopathological examination using standard laboratory methods. Descriptive statistics were computed and expressed as Mean ± SD. One-way ANOVA and Turkeys test was performed. P value ≤0.05 was considered statistically significant. Results: Acute toxicity LD50 of STCD was observed to be ≥2404.2 mg/kg body weight. An increase in the percentage body weight difference of 8.39% and 2.86% was observed for 200 and 400 mg/kg STCD groups. Also, the liver weight was observed to increase in 400 mg/kg (3.92 ± 1.42) in comparison to the control group (3.48 ± 1.61), a decrease in the kidney weight was observed in all groups administered STCD in comparison to the control group. Administration of STCD at both 200 and 400 mg/kg revealed a decrease in the concentration of the hepatic biomarkers AST, ALT, ALP, TP, Albumin, Total and conjugated bilirubin. The kidney biomarker Urea was observed to decrease in concentration for 200 mg/kg STCD (4.60 ± 1.83) and 400 mg/kg STCD (4.76 ± 0.74) when compared to the control group (6.32 ± 2.74). A decrease in Creatinine was observed in 200 mg/kg (91.80 ± 34.69) and 400 mg/kg (98.60 ± 15.53) in comparison to the control group (117.60 ± 42.88). The histological examination of the liver of rats administered STCD revealed structural normal central vein, hepatocytes and portal tract. The kidney examination revealed normal glomeruli and normal tubule. Conclusion: The findings of this study opine that STCD improved the health of both the liver and kidney as evidenced via the biomarkers and histological examinations of the liver and kidney. This study therefore recommends the intake of STCD at moderate doses for improved liver and kidney function due to its bioactive compounds and nutritional content.展开更多
文摘Based on the measured data, suspended sediment concentration, surface sediment grain size, current and waves, the sediment transport mechanisms and pathways in the Phoenix Island area were analyzed using methods of flux decomposition and Grain Size Trend Analysis(GSTA). The results show that net suspended sediment is mainly transported by average current, Stokes drift, and gravitational circulation. The transport direction of suspended sediment is varying and basically following the direction of residual tidal currents. Surface sediment transport pathways are primarily parallel to the coastline along with two convergent centers. Waves and longshore currents have a significant influence on sediment transport, but the influence is limited due to a steep and deep underwater bank. Tidal current is the main controlling factor for sediment transport, especially in the deep water area. Neither suspended nor surface sediment is transported towards the southwest. The South Shandong Coastal Current(SSCC) has little effect on sediment transport processes in the nearshore area of Phoenix Island.
基金supported by Grant from College of Medicine and Health Sciences,Sultan Qaboos University,Sultanate of Oman
文摘Objective: To investigate different types of dates and medical properties of influencing blood clotting and wound healing in an animal model. Methods: Three different cultivars of dates(Ajwa, Khalas, and Fardh) were examined in-vivo, for blood clotting and wound healing using CD1 mice of both sexes. Study of toxicity to animals was performed accordingly prior to further investigations. The ethanolic extracts were given orally to animals as a constituent in their daily water. Blood samples were obtained from the mice inferior vena cava to carry out the prothrombin time(PT) assay using the manual method and confirmed using a semi-automated machine. The bleeding time(BT) assay was performed using the cutting technique. In the wound healing analysis, a small cut(5-10 mm) in the skin overlying the thigh was conducted in all mice under anesthesia. The diameter of the cut and healing status were measured on a daily basis throughout the time of the experiment using a roller. Results: Ajwa was able to elevate both PT and BT(P<0.05), significantly in a time-dependent manner followed by Khalas date(P<0.05). The results of PT and BT of Fardh date were found to be very close to those of the control group(P<0.05). Despite its activity as an anticoagulant, Khalas date showed a potential property to enhance wound healing in contrast to other dates and the control groups in this study. Conclusions: Omani Khalas date fruit has both antithrombotic as well as wound healing properties. The results open a new gate with these fruits for exploring the potential component(s) that may play an important role in antithrombotic as well as wound healing process.
文摘Background: Dopamine has been known to facilitate male sexual function. Methods: The effect of aqueous extract (140 mg/kg) of Phoenix dactylifera date palm pollen on sexual behavior and determining of dopamine transmission in the nucleus accumbens was studied in male rats using in vivo microdialysis. Results: Releasing of dopamine increased significantly in the nucleus accumbens when a receptive female was introduced behind a screen (p 0.001). During copulation, dopamine increased markedly in control and treated rats. Phoenix dactylifera Date Palm Pollen enhanced the orientation of males towards females by increasing mounting and ano-genital investigatory behavior. Improving of sexual behavior and dopamine release was higher in treated rats in comparison with control (p 0.001). Conclusion: These results indicate a neurochemical basis for interaction between dopaminergic agents and male sexual behavior. Therefore, Phoenix dactylifera Date Palm Pollen seems to act as a dopamine agonist and to cure male infertility. It can be used as an aphrodisiac that leads to further increases in dopamine release.
文摘Aim of study: Ancient literature alluded to the use of a number of plants/preparations as sex enhancer. One of such botanicals is Phoenix dactylifera in which the pollen grain has been acclaimed to be used as an aphrodisiac. However, the validity has not been scientifically tested. Dopamine is known to facilitate male sexual function. Therefore, the present study was undertaken to evaluate the effect of aqueous extract of Phoenix dactylifera pollen on the sexual behavior of male rats and to measure of serum Estradiol and Testostrone. Also, dopamine transmission in the nucleus accumbence (NAc) was studied in male rats using in vivo microdialysis. Methods and Materials: sixty male rats were randomized into 6 groups (A-F). Group A received 0.2 ml of Normal Saline mixed with Dimethyl Sulphate (DMSO), while groups B-F were injected same volume containing 35 mg/kg, 70 mg/kg, 105 mg/kg, 140 mg/kg and 350 mg/kg of DPP extract, respectively. Sexual behavioral parameters including mounting, intromission and ejaculation frequencies and latencies were recorded in male rats one hour after injection of extract by mating with a receptive female (1:1). The male serum testosterone and estradiol concentrations were also determined. Results: All doses stimulated male sexual behavior. Extract significantly increased mount, ejaculation, intromission frequencies and ejaculation latency in comparison to controlled ones (p 0.001). Mount and intromission latencies significantly reduced (p 0.001). Maximum effect was observed in dose 140 mg/kg. This extract was found to enhance Testestrone, Estradiol and the orientation of males toward female ones by increasing mounting and ano-genital investigatory behavior. Conclusions: Data from this study identified that the aqueous extract of Phoenix dactylifera pollen grain enhanced sexual behaviour in male rats. The improved sexual appetitive behaviour in male rats may be attributed, to the alkaloids, saponins, and or flavonoids since these phytochemicals has engorgement, androgen enhancing. Also, our findings support the traditional use of this plant as acclaimed aphrodisiac and for the treatment of pre-ejaculation and impotency.
文摘Phoenix, a very beautiful and popular image in China,like dragon, is an imagined and legendary animal existing only in people's mind. It is such an important component of Chinese culture that we can see a sort of phenomenon called phoenix phenomenon comes into being in Chinese culture, which deserves efforts to elaborate and whose origin is worth probing. As the totem worshipped by the ancient Chu people, phoenix also displays the basic features of Chinese culture: integratedness and inclusiveness.
基金Supported by Faculty Mentored Undergraduate Research Award Program scheme wide grant No FRP/OMC/14/002
文摘Objective:To evaluate and compare the antioxidant activity,total phenolic contents(TPCs) and in vitro antidiabetic activity of various pits extracts obtained from five Omani date cultivars.Methods:Sun-dried mature fruits of five Omani date varieties,namely,Fardh,Naghal,Khalas,Khinazi and Khasab were purchased from the local market in Muscat,Oman in the month of September 2014.Four seed extracts viz.water,ethanol,methanol and acetone were prepared for each date variety and their antioxidant activities were investigated by 1,1-diphenyl-2-picrylhydrazyl,hydrogen peroxide scavenging method and reducing power assay method,respectively.In vitro antidiabetic activity of the date pit extracts was evaluated by measuring their inhibitory effect on a-glucosidase and aamylase level.TPCs were also quantified colorimetrically.Results:The results indicated that TPC of date seeds was solvent dependent.Acetone,ethanol and methanol were found to be significantly better solvents than water in extracting phenolic compounds from the date seeds.Pit extracts exhibited moderate to good in vitro antioxidant activity and increased reducing power.Among all date pit extracts,water extract exhibited significant in vitro antidiabetic activity in comparison to standard drug,acarbose.Conclusions:The present study confirms that disposed waste of Omani dates is a rich source of dietary antioxidant because of its high TPC.The pits due to their inhibitory effects on a-glucosidase and a-amylase level could be used as a monotherapy along with an appropriate diabetic diet and exercise or might be in conjunction with antidiabetic therapy to manage and prevent progression of diabetes.
文摘Our overall knowledge of the medicinal uses of plants suggests that natural compounds could be useful in the treatment of cutaneous fungal infections in tropical regions. Furthermore, the possibilities of treatment using plant extracts may be even broader than is already known when one considers plants that have not been extensively studied in this context, such as the regional species Phoenix dactylifera and Ziziphus spina-christi. This study compared the antimicrobial activity of Phoenix dactylifera and Ziziphus spina-christi extracts in terms of their biochemical and molecular effects on Candida albicans (ATCC CA 10231). These effects included altered levels of intracellular sterols, changes in the permeability of the cell membrane, and changes in the TEF1: QRTTEF1, CaERG1: ERG1, CdERG12: CdERG1, and ERG25: ERG25 genes. Scanning electron microscopy (SEM) was used to identify morphological characteristics, and energy-dispersive X-ray spectroscopy (EDAX) analyses were conducted. In treated samples, the SEM and EDAX analyses showed cell cavities and shrinkage of the cell wall, and the number of cells was reduced to only a few abnormal cells as compared with that in the untreated samples. Yttrium was detected in the cells treated with Z. spina-christi, and high levels of osmium were detected in the cells treated with P. dactylifera. Compared with control cells, cells exposed to the concentration 150 μl/ml of Z. spina-christi extract had an average sterol concentration that was nearly 3 times higher, while the concentration was 5.5 times higher for cells treated with the 150 μl/ml of P. dactylifera extract. The ethanol extracts affected the permeability of C. albicans cell membrane. Gene sequencing showed gaps and mismatches in the ERG1, ERG12, and ERG25 genes after treatment with P. dactylifera and Z. spina-christi extracts compared with that in the controls. The results were highly significant (p ≤ 0.01). We conclude that the ethanol extracts of P. dactylifera and Z. spina-christi have antimicrobial activity through several mechanisms in the yeast cell.
文摘The potential of the Senegal date palm (</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span><span><i><span style="font-family:""><span style="font-family:Verdana;">Phoenix </span><span style="font-family:Verdana;">reclinata</span></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"></i></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) seed bio-char to remove chromium (VI) ions from aqueous solutions by adsorption was investigated. Adsorption experiments were performed on the tannery effluent and standard aqueous solutions of chromium (VI) for varying adsorbent doses, contact times, pH, temperatures, and interfering anionic ions by batch mode. </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span><span><i><span style="font-family:""><span style="font-family:Verdana;">Phoenix </span><span style="font-family:Verdana;">reclinata</span></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"></i></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> seeds (PRS) bio-char was used in the investigation and the residual chromium (VI) was determined using the atomic absorption spectrophotometer (AAS). Results showed that the bio-char removed up to 86% of chromium (VI) ions in the effluent at pH 2. The highest percentage adsorption registered was 97% in an aqueous solution of chromium (VI) at pH 1 and this dropped to less than 10% at pH greater than 2. A general increase in adsorption with</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> the</span></span></span><span><span><span style="font-family:""> <span style="font-family:Verdana;">increase</span><span style="font-family:Verdana;"> in temperature was observed but reduced when the temperature was raised beyond 60</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">°</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">C. The presence of interfering anions caused a reduction in the adsorption of chromium (VI) ions. The adsorption process fitted both Langmuir and Freundlich adsorption models and the maximum adsorption capacity, </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span><span><i><span style="font-family:""><span style="font-family:Verdana;">Q</span><sub><span style="font-family:Verdana;">o</span></sub></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><sub><span style="font-family:Verdana;"></i></span></sub></i></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">, was 0.6593 mg/g. Thus, PRS bio-char can </span><span style="font-family:Verdana;">therefore</span><span style="font-family:Verdana;"> be used by industries and institutions like secondary schools to treat effluents that contain chromium (VI).
文摘Background: The synergistic mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera (STCD) aqueous extract is a common drink in Port Harcourt, Nigeria. It is assumed to have various health benefits. However, the synergistic mixture of the content has not been studied scientifically, hence the need to evaluate its effect on the liver and kidney being part of the body’s metabolic organs. Aim: This study evaluated the synergistic mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera (STCD) aqueous extract in male albino rats. Methods: Acute toxicity LD<sub>50</sub> of STCD was carried out, afterwards, fifteen male albino rats were grouped into three groups with 5 rats in each group;Control, 200 mg/kg, 400 mg/kg STCD. The rats were administered STCD orally 24 hourly, for 21 days, with feed and water ad libitum. At the end of the experiment, blood samples were collected for biochemical analysis of the liver and kidney biomarkers, while the liver and kidney tissues were harvested for histopathological examination using standard laboratory methods. Descriptive statistics were computed and expressed as Mean ± SD. One-way ANOVA and Turkeys test was performed. P value ≤0.05 was considered statistically significant. Results: Acute toxicity LD50 of STCD was observed to be ≥2404.2 mg/kg body weight. An increase in the percentage body weight difference of 8.39% and 2.86% was observed for 200 and 400 mg/kg STCD groups. Also, the liver weight was observed to increase in 400 mg/kg (3.92 ± 1.42) in comparison to the control group (3.48 ± 1.61), a decrease in the kidney weight was observed in all groups administered STCD in comparison to the control group. Administration of STCD at both 200 and 400 mg/kg revealed a decrease in the concentration of the hepatic biomarkers AST, ALT, ALP, TP, Albumin, Total and conjugated bilirubin. The kidney biomarker Urea was observed to decrease in concentration for 200 mg/kg STCD (4.60 ± 1.83) and 400 mg/kg STCD (4.76 ± 0.74) when compared to the control group (6.32 ± 2.74). A decrease in Creatinine was observed in 200 mg/kg (91.80 ± 34.69) and 400 mg/kg (98.60 ± 15.53) in comparison to the control group (117.60 ± 42.88). The histological examination of the liver of rats administered STCD revealed structural normal central vein, hepatocytes and portal tract. The kidney examination revealed normal glomeruli and normal tubule. Conclusion: The findings of this study opine that STCD improved the health of both the liver and kidney as evidenced via the biomarkers and histological examinations of the liver and kidney. This study therefore recommends the intake of STCD at moderate doses for improved liver and kidney function due to its bioactive compounds and nutritional content.