Hyperlactemia associated with secondary hepatocellular carcinoma resection in relation to circulation stability and quality of recovery:A case report

BACKGROUND Intraoperative hyperlactatemia often affects circulatory stability,vital organ function,and postoperative recovery,poses a serious prognostic risk,and requires considerable attention from anesthesiologists.Here,we describe a case of hyperlactatemia during the postoperative resection of liver metastases after chemotherapy for sigmoid colon cancer.This did not affect the patient's circulatory stability or quality of awakening,which is rarely reported in clinical practice.We present our management experience with the aim of providing a reference for future studies and clinical practice.CASE SUMMARY A 70-year-old female patient was diagnosed with postoperative liver metastasis following chemotherapy for sigmoid colon cancer.Laparoscopic right hemicolectomy and cholecystectomy under general anesthesia were required.Metabolic disorders,primarily hyperlactatemia,often occur intraoperatively.After treatment,other indices quickly returned to normal,lactate levels decreased slowly,and hyperlactatemia persisted during the awakening period.However,this did not affect the patient's circulatory stability or awakening quality.This condition has rarely been clinically reported.Therefore,we report our management experience in order to guide clinical practice in this regard.Hyperlactatemia did not affect circulatory stability or the quality of awakening.We considered that active intraoperative rehydration avoided serious harm to the organism caused by hyperlactatemia due to insufficient tissue perfusion,while hyperlactatemia caused by decreased lactate clearance due to impaired liver function associated with surgical resection had a mild effect on the function of important organs.CONCLUSION Active intraoperative rehydration avoided serious harm to the organism caused by hyperlactatemia.Strengthening body temperature protection could improve lactate circulation.

Intestinal microecological transplantation for a patient with chronic radiation enteritis:A case report

BACKGROUND The gut microbiota is strongly associated with radiation-induced gut damage.This study aimed to assess the effectiveness and safety of intestinal microecological transplantation for treating patients with chronic radiation enteritis.CASE SUMMARY A 64-year-old female with cervical cancer developed abdominal pain,diarrhea,and blood in the stool 1 year after radiotherapy.An electronic colonoscopy was performed to diagnose chronic radiation enteritis.Two courses of intestinal microecological transplantation and full-length 16S rRNA microbiological analysis were performed.The patient experienced short-and long-term relief from symptoms without adverse effects.Whole 16S rRNA sequencing revealed significant differences in the intestinal flora’s composition between patient and healthy donors.Pathogenic bacteria,such as Escherichia fergusonii and Romboutsia timonensis,were more in the patient.Beneficial bacteria such as Faecalibacterium prausnitzii,Fusicatenibacter saccharivorans,Ruminococcus bromii,and Bifidobacterium longum were more in the healthy donors.Intestinal microbiota transplantation resulted in a significant change in the patient's intestinal flora composition.The composition converged with the donor's flora,with an increase in core beneficial intestinal bacteria,such as Eubacterium rectale,and a decrease in pathogenic bacteria.Changes in the intestinal flora corresponded with the patients'alleviating clinical symptoms.CONCLUSION Intestinal microecological transplantation is an effective treatment for relieving the clinical symptoms of chronic radiation enteritis by altering the composition of the intestinal flora.This study provides a new approach for treating patients with chronic radiation enteritis.

Pursuing the Distilled Good Practices to Improve the Quality of Environmental Impact Assessment Reports and Hence Enhance the EIA Effectiveness and Help Address the Concerns of Project Proponents:An Indian Context

Despite a wealth of literature on the different facets of the EIA,and copious theoretical knowledge and practical experience,the general agreement is eluding definitions of EIA effectiveness,quality,and good practices.There are apprehensions about EIA meeting its basic objectives while project proponents continue to treat EIA as an impediment to development.Governments tend to adopt a“practical”approach,sacrificing pillars of EIA and overlooking the prime objective of environmental protection.Based on an extensive literature study and the author’s long EIA-related experience,some key workable practices for the EIA process are elaborated.Meticulous scoping using different sets of lenses,spotlighting significant impacts to determine the breadth and depth of EIA reports for focussed EIAs,robust EIA review and decision-making,commitment from the regulators for environmental protection,and use of strategic planning,strategic environmental assessment,and tiering practices are expected to address scholars’apprehensions and project proponents’concerns.

Patient-centric periodontal research:A pioneering application of patient-reported outcome measures

Conventional dentistry or periodontal research often ignores the human component in favor of clinical outcomes and biological causes.Clinical research is driven by the statistical significance of outcome parameters rather than the satisfaction level of the patient.In this context,patient-centric periodontal research(PCPR)is an approach that considers the patient´s feedback concerning their functional status,experience,clinical outcomes,and accessibility to their treatments.It is argued that data self-reported by the patient might have low reliability owing to the confounding effect of their personal belief,cultural background,and social and economic factors.However,literature has shown that the incorporation of“patient-centric outcome”components considerably enhances the validity and applicability of research findings.Variations in the results of different studies might be due to the use of different and non-standardized assessment tools.To overcome this problem,this editorial enlists various reliable tools available in the literature.In conclusion,we advocate that the focus of researchers should shift from mere periodontal research to PCPR so that the results can be effectively applied in clinical settings and the therapeutic strategy can also change from mere periodontal therapy to patient-centric periodontal therapy.

Quality of life and psychological distress in end-stage renal disease patients undergoing hemodialysis and transplantation

BACKGROUND Among diverse profound impacts on patients’quality of life(QoL),end-stage renal disease(ESRD)frequently results in increased levels of depression,anxiety,and stress.Renal replacement therapies such as hemodialysis(HD)and transplantation(TX)are intended to enhance QoL,although their ability to alleviate psychological distress remains uncertain.This research posits the existence of a significant correlation between negative emotional states and QoL among ESRD patients,with varying effects observed in HD and TX patients.AIM To examine the relationship between QoL and negative emotional states(depression,anxiety,and stress)and predicted QoL in various end-stage renal replacement therapy patients with ESRD.METHODS This cross-sectional study included HD or TX patients in the Eastern Region of Saudi Arabia.The 36-item Short Form Survey and Depression Anxiety Stress Scale(DASS)was used for data collection,and correlation and regression analyses were performed.RESULTS The HD and TX transplantation groups showed statistically significant inverse relationships between QoL and DASS scores.HD patients with high anxiety levels and less education scored low on the physical component summary(PCS).In addition,the results of the mental component summary(MCS)were associated with reduced depression.Compared with older transplant patients,TX patients’PCS scores were lower,and depression,stress,and negative working conditions were highly correlated with MCS scores.CONCLUSION The findings of this study revealed notable connections between well-being and mental turmoil experienced by individuals undergoing HD and TX.The PCS of HD patients is affected by heightened levels of anxiety and lower educational attainment,while the MCS of transplant patients is influenced by advancing age and elevated stress levels.These insights will contribute to a more comprehensive understanding of patient support.

A Conceptually-Based Empirical Analysis on Quality Differences Between UK Annual Reports and US 10-K Reports

The International Accounting Standards Board （IASB） and the Financial Accounting Standards Board （FASB） stress the importance of high-quality ＇financial reports. From a scientific point of view, however, major methodological drawbacks can arise when trying to arrive at a comprehensive assessment and evaluation of the decision usefulness of financial reports. In this conceptually-based exploratory study, the authors construct a 33-item index aimed at operationalizing decision usefulness in terms of the fundamental and enhancing qualitative characteristics laid out in the conceptual framework （CF） of the IASB （2010）. Using a matched-pairs sample design, which includes 70 UK annual reports and 70 US 10-K reports for 2010, the results of test-retest and inter-rater reliability tests show that these multiple items, which were based on items used in previous research, can be measured in a reliable manner. At the same time, the results of an exploratory factor analysis indicate that the IASB qualitative characteristics cannot be measured separately when the 33-item index is applied. At an aggregate level, the results of paired-sample t-tests reveal that UK reports score on average higher than US 10-K reports, which suggests that the overall quality of UK reports is better. The findings of this study add to the existing literature on the empirical evaluation of the effects of international accounting standards, showing that, as compared with 10-K reports, UK annual reports provide more information on topics such as corporate social responsibility （CSR）, corporate governance, and annual bonus schemes. On the other hand, US reports outperform UK reports with respect to the content of fair value information, cash flow statements, off-balance financing, and audit reporting.

Annual Reports of Non-profit Organizations （NPOs）： An Analysis

Non-profit organizations （NPOs） in Malaysia are not subjected to statutory requirement to follow the accounting standards when preparing their annual reports. This study analyzed the annual reports of 100 NPOs registered with the Registry of Society （ROS） under the charity and religious categories. The objectives of this study are： （1） to determine the current state of reporting practices by NPOs; and （2） to describe the contents of a set of annual reports and the financial statement presentation of NPOs. This study found that there were variations in reporting practices among the charity and religious categories of NPOs. On average, the results show that NPOs do not focus on the disclosing information required by the ROS, the governing body of NPOs. This indicates that the regulators need to strongly practice enforcement to strengthen the compliance of the annual reports submission. Overall, the findings of this study provide useful information to regulators as a basis for preparing and presenting NPOs＇ annual report framework in the future.

A Comparative Analysis of Disclosures in Annual Reports

Public companies issue periodic annual reports to give information about the past financial and operational results while presenting the future strategies. Companies release non-financial information concerned with corporate sustainability issues like market share, customer loyalty, supply chain management, corporate governance, and human resources in annual reports as well as the audited financial reports. Annual reports, one of the important instruments of transparency and disclosure, are widely used by shareholders and stakeholders. Recent laws and regulations in the US, European Union, and Turkey require enhanced disclosures in annual reports. In the first part of this study, a comparative regulatory framework for annual reports will be established under the Sarbanes Oxley Act （SOX）, the Securities and Exchange Commission （SEC） filing requirements, the New Turkish Commercial Code, and regulations of Capital Markets Board （CMB） of Turkey. In the second part of this study, annual reports of four sample companies listed in the New York Stock Exchange （NYSE） and Corporate Governance Index of Borsa Istanbul will be discussed in the light of disclosure requirements of Form 20-F. Findings of this study support the hypothesis which states that regulatory environment has a positive impact on the quantity and quality of disclosures. Attention is drawn to the need for global standardization to reduce the reporting variances and the need for independent audit of annual reports to increase the reliability.

Annual Report of SGCC on Transactions of Electric Power Market in 2009

Market construction Overview In 2009, the electric power market expanded continuously. New installed capacity put into production within the coverage of the State Grid Corporation

Importance of reporting quality: An assessment of the COVID-19 meta-analysis laboratory hematology literature

BACKGROUND Meta-analysis,a form of quantitative review,is an attempt to combine data from multiple independent studies to improve statistical power.Because of the complexity of process involved in study selection,data analysis,and evaluation of bias and heterogeneity,checklists have been prepared by the Institutes of Medicine(IOM),Preferred Reporting Items for Systemic Reviews and Metaanalyses(PRISMA),and Meta-analyses of Observational Studies in Epidemiology(MOOSE)to standardize the reporting quality of a meta-analysis.AIM To use these checklists to assess the reporting quality of the coronavirus disease-2019(COVID-19)meta-analysis literature relevant to laboratory hematology.METHODS After a search of the literature 19 studies were selected for analysis,including 10 studies appearing in the preprint literature(studies that can be identified by database search but have not yet completed peer review).RESULTS The average IOM(76%of required elements completed),PRISMA(75%of required elements completed),and MOOSE(60%of required elements completed)scores enumerated demonstrated a reporting quality inferior to that of earlier reports of pathology and medicine meta-analyses.There was no statistically significant difference in performance between accepted/published and preprint studies.Comparison of the results of PRISMA and MOOSE studies demonstrated a weak positive correlation(Pearson’s correlation coefficient=0.39).CONCLUSION The most common deficits in the studies included sensitivity analysis,assessment for bias,and details of the search strategy.Although the COVID-19 laboratory hematology meta-analysis literature can be a helpful source of information,readers should be aware of these reporting quality deficits.

AQSIQ Publishes China Annual Report on Technical Barriers to Trade (2007)

On September 11, 2007, Qi Xiufen, Director of the International Department of the General Administration of Quality Supervision, Inspection and Quarantine of China (AQSIQ), published the China Annual Report on Technical Barriers to Trade.Wang Nini, Director of the Standard, Law and Regulation Center of AQSIQ, gave a detailed explanation of the contents of the report.……

How about the reporting quality of case reports in nursing field?

BACKGROUND As a significantly important part of clinical practice,the professional nursing process can be advanced in many ways.Despite the fact that case reports are regarded to be of a lower quality grade in the hierarchy of evidence,one of the principles of evidence-based medicine is that decision-making should be based on a systematic summary of evidence.However,the evidence on the reporting characteristics of case reports in the nursing field is deficient.AIM To use the CARE guidelines to assess reporting quality and factors influencing the quality of case reports in the nursing field.METHODS Nursing science citation indexed(SCI-indexed)journals were identified from the professional website.Each of the identified journals was searched on their website for articles published before December 2017.Twenty-one sub-items on the CARE checklist were recorded as“YES”,“PARTLY”,or“NO”according to information reported by the included studies.The responses were assigned corresponding scores of 1,0.5,and 0,respectively.The overall score was the sum of the 21 sub-items and was defined as“high”(more than 15),“medium”(10.5 to 14.5),and“low”(less than 10).The means,standard deviations,odds ratios(OR),and the associated 95%confidence interval(CI)were determined using Stata 12.0 software.RESULTS Ultimately,184 case reports from 16 SCI-indexed journals were identified,with overall scores ranging from 6.5 to 18(mean=13.6±2.3).Of the included case reports,10.3%were regarded low-quality,52.7%were considered middle-quality,and 37%were regarded high-quality.There were statistical differences in the mean overall scores of the included case reports with funding versus those without funding(14.2±1.7 vs 13.6±2.4,respectively;P=0.4456)and journal impact factor<1.8 versus impact factor≥1.8(13.3±2.3 vs 13.6±2.4,respectively;P=0.4977).Five items from the CARE guidelines,5a(Patient),6(Clinical findings),8c(Diagnostic reasoning),9(Therapeutic intervention),and 11d(The main take-away lessons)were well-reported(Reporting rate more than 90%)in most of the included case reports.However,only three items,2(Keywords,OR=0.42,95%CI:0.19-0.92,P=0.03),4(Introduction,OR=0.35,95%CI:0.15-0.83,P=0.017),and 11b(The relevant medical literature,OR=0.19,95%CI:0.06-0.56,P=0.003)were considered better-reported after the CARE guidelines published in 2013.CONCLUSION The reporting quality of case reports in the nursing field apparently has not improved since the publication of the CARE guidelines.

Are the data on quality of life and patient reported outcomes from clinical trials of metastatic non-small-cell lung cancer important?

Majority of the patients with advanced non-small-cell lung cancer(NSCLC)experience two or more disease related symptoms,which may have a negative impact on their health-related quality of life(HR QOL).These patients prefer a therapy that would improve disease related symptoms,as opposed or treatment that slightly prolongs their survival without improving symptoms.The improvements of the symptoms augment the significance of improved response rates or progression free survivals.The choice of the questionnaires to evaluate patients-reported outcomes(PROs)and HRQOL benefits and methods of collecting the data and their interpretations are very important and are discussed in this manuscript.PROs and HR QOL outcomes are important in patients with advanced NSCLC only when the data are collected and analyzed correctly.Then they can be viewed as components of the total value of a treatment,providing a comprehensive picture of the benefits and risks of anticancer therapies.Enabling the patients to feel during the last months of their lives more comfortable and not be dependent on their loved ones is a very important task in the treatment of advanced NSCLC.

2019 Annual Report of China's Paper Industry

According to the 2019 annual report of China's Paper Industry by China Paper Association(CPA),in 2019,there were about 2700 paper&board manufacturers in China's Mainland.The total production of paper&board was 107.65 million tons,increased by 3.16%and the total consumption was 107.04 million tons,increased by 2.54%compared with 2018,respectively,paper&board per capita consumption was 75 kg(counted in 1.4 billion people).This report includes a rather elaborate analysis of the China's paper industry and is provided for the readers'reference.

Effects of PHC on Water Quality of Jiaozhou Bay Ⅰ. Annual Variation of PHC Content

Based on investigation data on PHC in Jiaozhou Bay, China from 1979 to 1983, the monthly, seasonal and annual variations of PHC content in Jiaozhou Bay were studied. The results showed that from 1979 to 1983, Jiaozhou Bay was polluted by PHC seriously and then slightly in spring and summer, while Jiaozhou Bay was polluted by PHC slightly in autumn. During 1979 -1983, PHC content in the water body of Jiaozhou Bay decreased year by year, and it was close to the background value gradually. Moreover, the reduction was obvious in spring and summer but very slight in autumn. Therefore, the water quality of Jiaozhou Bay became better.

Reporting quality of systematic review protocols of interventions for knee osteoarthritis:a systematic review protocol

Background:Knee osteoarthritis is a chronic degenerative disease responsible for a substantial disease burden worldwide.Multiple protocols of systematic reviews of interventions for knee osteoarthritis have been published,but their reporting quality remains unknown,with potential influencing factors failing to be explored.Therefore,the present systematic review was designed to fill those gaps in our knowledge.Methods:The protocols of systematic reviews of interventions for knee osteoarthritis will be searched systematically through the PubMed and Embase online databases from inception to May 2021.Two reviewers will independently screen the literature and abstract data,and cross-check the results.The reporting quality of protocols included in the review will be evaluated using the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols checklist,and potential influencing factors(e.g.,methodologist involvement and number of authors)for reporting quality will be explored using univariable and multivariable linear regression methods.The general information of the protocols included in the review will be reported qualitatively.Excel 2019 and Stata 13.0 software will be used to manage and analyze the data.P-values<0.05 will be considered statistically significant.Results:The results of this methodological systematic review will be submitted to a peer-reviewed journal for publication.Conclusion:The systematic review will provide evidence of the reporting quality of protocols of systematic reviews of interventions for knee osteoarthritis.The evidence from the present review will be available to inform the reporting of future protocols.

ANNUAL WORKING REPORT OF CAS DIVISION OF MATHEMATICS & PHYSICS (Abridged)

Ⅰ. ACADEMIC ASSIGNMENTS ACHIEVED 1. Hosted Key State-entrusted Consultancy Projects: (1) Completion of the advisory service which had been set for the national Eighth Five-year Plan entrusted by the national authorities. (2) Achievement of the consultancy work for key programs of basic research also entrusted by

ANNUAL WORKING REPORT OF CAS DIVISION OF BIOLOGY (Abridged)

Ⅰ. A REVIEW OF OUR WORK FROM 1994 TO 1996 1. Entrusted by the CPC central committee and the State Council, our Division completed its counseling assignments to the "Decision on Speeding up China’s S&T Progress Jointly Decreed by the Party’s Central Committee and the State Council," "An Outlined Report on the Train of Thought for Devising S&T Development in the National Ninth Five-year Plan & the Long-term Scheme for National S&T Development up to 2010," "The Ninth Five-year Plan and Long-term Scheme for National S&T(?)

Physicians’ Use of Patients’ Daily Reports of Quality of Life to Evaluate Treatment Response in Phase I Cancer Trials

For cancer patients on Phase I trials, one of the most important physician decisions is whether or not patients are deriving benefit from therapy. With an increasing number of cytostatic treatment agents, the criteria to determine patient response to Phase I treatment has become harder to define. Physicians are increasingly looking to patient-reported outcomes (PROs) such as quality of life (QOL) to help evaluate treatment response. Electronic daily diary (EDD) devices can be used by patients to report their QOL over extended periods of time, thereby providing a more accurate picture of how patients are affected by treatment on a daily basis. However, questions remain about how to integrate this patient-reported information into decisions about Phase I treatment. This study investigated how physicians use patients’ daily QOL reports to evaluate patient response to Phase I treatment. Data were collected over a 4-month period from Phase I patients (N = 30) and physicians (N = 3) in an NCI-designated comprehensive cancer center. Patients completed daily QOL reports using EDD devices and physicians were provided with a summary of patients’ QOL before each visit. After the visit, doctors recorded their treatment decision and also rated the importance of four biomedical factors (Toxicity, Imaging, Labs, and Performance Status) and QOL in their treatment decision for that visit. Although physicians rated QOL as being very important in evaluating treatment response, in practice, when predictors of their decisions were analyzed, results showed they relied exclusively on biomedical data (Toxicity, Imaging) to make Phase I treatment decisions. Questions remain about the utility and effective integration of QOL and biomedical data in clinical decision-making processes in Phase I clinical trials.

Public Agenda, Media Agenda and Policy Communication Process of Government Annual Reports:Based on the Survey in 19 Chinese Cities

Promoting direct policy communication between policy makers and the public is both an important function of government annual reports (GARs) and a key issue in democratic politics.According to this survey,conducted in 19 major cities in China,to promote the policy communication function of the GARs the government should make full use of changes in public policy communication habits and the convergence of public policy preferences in different groups while dealing with routine problems such as “public opinion deficits” and “being popular among the institutional staff but unnoticed the non-institutional staff.”