Parkinson’s disease(PD)was first described as a neurological disease by Dr.James Parkinson in 1817 as a“shaking palsy”.Since that time,much more is known about the pathophysiology of PD yet the disease is still unc...Parkinson’s disease(PD)was first described as a neurological disease by Dr.James Parkinson in 1817 as a“shaking palsy”.Since that time,much more is known about the pathophysiology of PD yet the disease is still uncurable.The hallmark of the disease is often considered Lewy body neural inclusions in the substantia nigra pars compacta and other brain areas,although not all patients have these inclusions.The patients exhibit massive neuronal cell loss in the substantia nigra pars compacta,which is associated with the motor symptoms of tremor,bradykinesia,rigidity,and postural instability.PD is the second most common neurodegenerative disease after Alzheimer’s disease with a prevalence of around 1%of individuals over the age of 60.展开更多
We analyze the properties of a focused Laguerre–Gaussian(LG)beam propagating through anisotropic ocean turbulence based on the Huygens–Fresnel principle.Under the Rytov approximation theory,we derive the analytical ...We analyze the properties of a focused Laguerre–Gaussian(LG)beam propagating through anisotropic ocean turbulence based on the Huygens–Fresnel principle.Under the Rytov approximation theory,we derive the analytical formula of the channel capacity of the focused LG beam in the anisotropic ocean turbulence,and analyze the relationship between the capacity and the light source parameters as well as the turbulent ocean parameters.It is found that the focusing mirror can greatly enhance the channel capacity of the system at the geometric focal plane in oceanic turbulence.The results also demonstrate that the communication link can obtain high channel capacity by adopting longer beam wavelength,greater initial beam waist radius,and larger number of transmission channels.Further,the capacity of the system increases with the decrease of the mean squared temperature dissipation rate,temperature-salinity contribution ratio and turbulence outer scale factor,and with the increase of the kinetic energy dissipation rate per unit mass of fluid,turbulence inner scale factor and anisotropy factor.Compared to a Hankel–Bessel beam with diffraction-free characteristics and unfocused LG beam,the focused LG beam shows superior anti-turbulence interference properties,which provide a theoretical reference for research and development of underwater optical communication links using focused LG beams.展开更多
This paper presents a novel view of the impact of electron collision off-axis positions on the dynamic properties and relativistic nonlinear Thomson inverse scattering of excited electrons within tightly focused, circ...This paper presents a novel view of the impact of electron collision off-axis positions on the dynamic properties and relativistic nonlinear Thomson inverse scattering of excited electrons within tightly focused, circularly polarized laser pulses of varying intensities. We examine the effects of the transverse ponderomotive force, specifically how the deviation angle and speed of electron motion are affected by the initial off-axis position of the electron and the peak amplitude of the laser pulse. When the laser pulse intensity is low, an increase in the electron's initial off-axis distance results in reduced spatial radiation power, improved collimation, super-continuum phenomena generation, red-shifting of the spectrum's harmonic peak, and significant symmetry in the radiation radial direction. However, in contradiction to conventional understandings,when the laser pulse intensity is relatively high, the properties of the relativistic nonlinear Thomson inverse scattering of the electron deviate from the central axis, changing direction in opposition to the aforementioned effects. After reaching a peak, these properties then shift again, aligning with the previous direction. The complex interplay of these effects suggests a greater nuance and intricacy in the relationship between laser pulse intensity, electron position, and scattering properties than previously thought.展开更多
The safety and effectiveness of magnetic resonance-guided focused ultrasound thalamotomy has been broadly established and validated for the treatment of essential tremor.In 2018,the first magnetic resonance-guided foc...The safety and effectiveness of magnetic resonance-guided focused ultrasound thalamotomy has been broadly established and validated for the treatment of essential tremor.In 2018,the first magnetic resonance-guided focused ultrasound system in Chinese mainland was installed at the First Medical Center of the PLA General Hospital.This prospective,single center,open-label,single-arm study was part of a worldwide prospective multicenter clinical trial(ClinicalTrials.gov Identifier:NCT03253991)conducted to confirm the safety and efficacy of magnetic resonance-guided focused ultrasound for treating essential tremor in the local population.From 2019 to 2020,10 patients with medication refractory essential tremor were recruited into this open-label,single arm study.The treatment efficacy was determined using the Clinical Rating Scale for Tremor.Safety was evaluated according to the incidence and severity of adverse events.All of the subjects underwent a unilateral thalamotomy targeting the ventral intermediate nucleus.At the baseline assessment,the estimated marginal mean of the Clinical Rating Scale for Tremor total score was 58.3±3.6,and this improved after treatment to 23.1±6.4 at a 12-month follow-up assessment.A total of 50 adverse events were recorded,and 2 were defined as serious.The most common intraoperative adverse events were nausea and headache.The most frequent postoperative adverse events were paresthesia and equilibrium disorder.Most of the adverse events were mild and usually disappeared within a few days.Our findings suggest that magnetic resonance-guided focused ultrasound for the treatment of essential tremor is effective,with a good safety profile,for patients in Chinese mainland.展开更多
Josephson junction plays a key role not only in studying the basic physics of unconventional iron-based superconductors but also in realizing practical application of thin-film based devices,therefore the preparation ...Josephson junction plays a key role not only in studying the basic physics of unconventional iron-based superconductors but also in realizing practical application of thin-film based devices,therefore the preparation of high-quality iron pnictide Josephson junctions is of great importance.In this work,we have successfully fabricated Josephson junctions from Co-doped BaFe_(2)As_(2)thin films using a direct junction fabrication technique which utilizes high energy focused helium ion beam(FHIB).The electrical transport properties were investigated for junctions fabricated with various He^(+)irradiation doses.The junctions show sharp superconducting transition around 24 K with a narrow transition width of 2.5 K,and a dose correlated foot-structure resistance which corresponds to the effective tuning of junction properties by He^(+)irradiation.Significant J_c suppression by more than two orders of magnitude can be achieved by increasing the He^(+)irradiation dose,which is advantageous for the realization of low noise ion pnictide thin film devices.Clear Shapiro steps are observed under 10 GHz microwave irradiation.The above results demonstrate the successful fabrication of high quality and controllable Co-doped BaFe_(2)As_(2)Josephson junction with high reproducibility using the FHIB technique,laying the foundation for future investigating the mechanism of iron-based superconductors,and also the further implementation in various superconducting electronic devices.展开更多
BACKGROUND Conventional magnifying endoscopy with narrow-band imaging(NBI)observation of the gastric body mucosa shows dominant patterns in relation to the regular arrangement of collecting venules,subepithelial capil...BACKGROUND Conventional magnifying endoscopy with narrow-band imaging(NBI)observation of the gastric body mucosa shows dominant patterns in relation to the regular arrangement of collecting venules,subepithelial capillary network,and gastric pits.AIM To evaluate the effectiveness of a new one-dual(near)focus,NBI mode in the assessment of the microscopic features of gastric body mucosa compared to conventional magnification.METHODS During 2021 and 2022,68 patients underwent proximal gastrointestinal endoscopy using magnification endoscopic modalities subsequently applying acetic acid(AA).The GIF-190HQ series NBI system with dual focus capability was used for the investigation of gastric mucosa.At the time of the endoscopy,the gastric body mucosa of all enrolled patients was photographed using the white light endoscopy(WLE),near focus(NF),NF-NBI,AA-NF,and AA-NF-NBI modes.RESULTS The WLE,NF and NF-NBI endoscopic modes for all patients(204 images)were classified in the same order into three groups.Two images from each patient for the AA-NF and AA-NF-NBI endoscopic modes were classified in the same order.According to all three observers who completed the work independently,NF magnification was significantly superior to WLE(P<0.01),and the NF-NBI mode was significantly superior to NF magnification(P<0.01).After applying AA,the three observers confirmed that AA-NF-NBI was significantly superior to AA-NF(P<0.01).Interobserver kappa values for WLE were 0.609,0.704,and 0.598,respectively and were 0.600,0.721,and 0.637,respectively,for NF magnification.For the NF-NBI mode,the values were 0.378,0.471,and 0.553,respectively.For AA-NF,they were 0.453,0.603,and 0.480,respectively,and for AA-NF-NBI,they were 0.643,0.506,and 0.354,respectively.CONCLUSION When investigating gastric mucosa in microscopic detail,NF-NBI was the most powerful endoscopic mode for assessing regular arrangement of collecting venules,subepithelial capillary network,and gastric pits among the five endoscopic modalities investigated in this study.AA-NF-NBI was the most powerful endoscopic mode for analyzing crypt opening and intervening part.展开更多
AIMTo evaluate intra-session repeatability and reproducibility of optical quality parameters measured at objective and subjective best focuses in a double-pass system.METHODSThirty Chinese healthy adults (19 to 40 yea...AIMTo evaluate intra-session repeatability and reproducibility of optical quality parameters measured at objective and subjective best focuses in a double-pass system.METHODSThirty Chinese healthy adults (19 to 40 years old) meeting our inclusion criterion were enrolled in the study. After a basic eye examination, two methods of optical quality measurement, based on subjective and objective best focuses were performed using the Optical Quality Analysis System (OQAS) with an artificial pupil diameter of 4.0 mm.RESULTSWith each method, three consecutive measurements of the following parameters: the modulation transfer function cutoff frequency (MTF<sub>cutoff</sub>), the Strehl<sup>2D</sup> ratio, the OQAS values (OVs) at contrasts of 100%, 20%, 9% and the objective scatter index (OSI) were performed by an experienced examiner. The repeatability of each method was evaluated by the repeatability limit (RL) and the coefficient of repeatability (COR). Reproducibility of the two methods was evaluated by intra-class correlation coefficient (ICC) and the 95% limits of agreement (Bland and Altman analysis). Thirty subjects, seven females and twenty three males, of whom 15 right eyes and 15 left eyes were selected randomly for recruitment in the study. The RLs (percentage) for the six parameters measured at objective focus and subjective focus ranged from 8.44% to 15.13% and 10.85% to 16.26%, respectively. The CORs for the two measurement methods ranged from 8.27% to 14.83% and 10.63% to 15.93%, respectively. With regard to reproducibility, the ICCs for the six parameters of OQAS ranged from 0.024 to 0.276. The 95% limits of agreement obtained for the six parameters (in comparison of the two methods) ranged from -0.57 to 42.18 (MTF<sub>cutoff</sub>), -0.01 to 0.23 (Strehl<sup>2D</sup> ratio), -0.02 to 1.40 (OV<sub>100%</sub>), -0.10 to 1.75 (OV<sub>20%</sub>), -0.14 to 1.80 (OV<sub>9%</sub>) and -1.46 to 0.18 (OSI).CONCLUSIONMeasurements provided by OQAS with either method showed a good repeatability. However, the results obtained from the two different measurement methods showed a poor reproducibility. These findings suggest that it might be best to evaluate patients' optical quality by OQAS using the best focus as chosen automatically by the instrument.展开更多
With the global rise of industries of the new-generation information technology, energy conservation and environmental protection, biotechnology, high-end manufacturing, new materials and clean-energy vehicles, tradit...With the global rise of industries of the new-generation information technology, energy conservation and environmental protection, biotechnology, high-end manufacturing, new materials and clean-energy vehicles, traditional metal materials cannot meet the functional requirements. Consequently, "three rare mineral resources", regarded as the best altemative for current and future new industries, have received much attention among industrial circles and have become a new focus during the present geological prospecting in China.展开更多
This article analyzed the importance of information monitoring and quick response on agricultural focuses and significant events, proposed the workflow and technical framework for information monitoring and quick resp...This article analyzed the importance of information monitoring and quick response on agricultural focuses and significant events, proposed the workflow and technical framework for information monitoring and quick response based on modern information technologies, and explained key technologies during implementation and the functional structure for prototype system of the technical support platform.展开更多
The current study investigates the hydrodynamic characteristics of gap resonance within a narrow gap formed by two adjacent boxes subjected to incident focused transient wave groups.A two-dimensional(2D)numerical wave...The current study investigates the hydrodynamic characteristics of gap resonance within a narrow gap formed by two adjacent boxes subjected to incident focused transient wave groups.A two-dimensional(2D)numerical wave tank based on the OpenFOAM package is utilized for this purpose.The weather-side box is fixed while the lee-side box is allowed to heave freely under wave actions.The effects of the focused wave amplitude and spectral peak period on the wave amplification within the gap,motion of the lee-side box,and wave forces(including horizontal and vertical wave forces)acting on each box are systematically examined.For comparison,another structural layout consisting of two fixed boxes is also considered.The results reveal that the release of the heave degree of freedom(DoF)of the lee-side box results in remarkably distinct resonance features.In the heave-box system,both its fluid resonant period and the period corresponding to the maximum heave displacement of the lee-side box are significantly larger(i.e.,1.6-1.7 times)than the fluid resonant period of the fixed-box system.However,the wave amplification factor inside the gap in the heave-box system is significantly lower than that in the fixed-box one.Both the variations of the maximum horizontal and vertical wave forces with the spectral peak period and their magnitudes are also significantly different between the two structural systems.展开更多
To improve the processing efficiency and extend the tuning range of 3D isotropic fabrication,we apply the simultaneous spatiotemporal focusing(SSTF)technique to a high-repetition-rate femtosecond(fs)fiber laser system...To improve the processing efficiency and extend the tuning range of 3D isotropic fabrication,we apply the simultaneous spatiotemporal focusing(SSTF)technique to a high-repetition-rate femtosecond(fs)fiber laser system.In the SSTF scheme,we propose a pulse compensation scheme for the fiber laser with a narrow spectral bandwidth by building an extra-cavity pulse stretcher.We further demonstrate truly 3D isotropic microfabrication in photosensitive glass with a tunable resolution ranging from 8μm to 22μm using the SSTF of fs laser pulses.Moreover,we systematically investigate the influences of pulse energy,writing speed,processing depth,and spherical aberration on the fabrication resolution.As a proof-of-concept demonstration,the SSTF scheme was further employed for the fs laser-assisted etching of complicated glass microfluidic structures with 3D uniform sizes.The developed technique can be extended to many applications such as advanced photonics,3D biomimetic printing,micro-electromechanical systems,and lab-on-a-chips.展开更多
On November 5-11,China hosted the 2014 APEC Economic Leaders’Week in Beijing.China’s Foreign Trade invited three experts focusing on APEC issues to share their thoughts on this year’s APEC meeting.1 What do you thi...On November 5-11,China hosted the 2014 APEC Economic Leaders’Week in Beijing.China’s Foreign Trade invited three experts focusing on APEC issues to share their thoughts on this year’s APEC meeting.1 What do you think of the meaning and impact of China’s holding APEC meeting this year?2 As we know,this theme of the summit is"Shaping the future through Asia-Pacific Partnership".There are three important issues of展开更多
基金supported by the Israel Science Foundation(ISF grant 1994/21 and 3252/21)Zuckerman(Zuckerman STEM leadership program)(to SS).
文摘Parkinson’s disease(PD)was first described as a neurological disease by Dr.James Parkinson in 1817 as a“shaking palsy”.Since that time,much more is known about the pathophysiology of PD yet the disease is still uncurable.The hallmark of the disease is often considered Lewy body neural inclusions in the substantia nigra pars compacta and other brain areas,although not all patients have these inclusions.The patients exhibit massive neuronal cell loss in the substantia nigra pars compacta,which is associated with the motor symptoms of tremor,bradykinesia,rigidity,and postural instability.PD is the second most common neurodegenerative disease after Alzheimer’s disease with a prevalence of around 1%of individuals over the age of 60.
基金This work was supported by the Science and Technology Innovation Training Program of Nanjing University of Posts and Telecommunications(Grant No.CXXZD2023080)the National Natural Science Foundation of China(Grant Nos.61871234 and 62001249)+1 种基金the Natural Science Foundation of Nanjing University of Posts and Telecommunications(Grant No.NY222133)the Open Research Fund of National Laboratory of Solid State Microstructures(Grant No.M36055).
文摘We analyze the properties of a focused Laguerre–Gaussian(LG)beam propagating through anisotropic ocean turbulence based on the Huygens–Fresnel principle.Under the Rytov approximation theory,we derive the analytical formula of the channel capacity of the focused LG beam in the anisotropic ocean turbulence,and analyze the relationship between the capacity and the light source parameters as well as the turbulent ocean parameters.It is found that the focusing mirror can greatly enhance the channel capacity of the system at the geometric focal plane in oceanic turbulence.The results also demonstrate that the communication link can obtain high channel capacity by adopting longer beam wavelength,greater initial beam waist radius,and larger number of transmission channels.Further,the capacity of the system increases with the decrease of the mean squared temperature dissipation rate,temperature-salinity contribution ratio and turbulence outer scale factor,and with the increase of the kinetic energy dissipation rate per unit mass of fluid,turbulence inner scale factor and anisotropy factor.Compared to a Hankel–Bessel beam with diffraction-free characteristics and unfocused LG beam,the focused LG beam shows superior anti-turbulence interference properties,which provide a theoretical reference for research and development of underwater optical communication links using focused LG beams.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.10947170/A05 and 11104291)the Natural Science Fund for Colleges and Universities in Jiangsu Province (Grant No.10KJB140006)+2 种基金the Natural Sciences Foundation of Shanghai (Grant No.11ZR1441300)the Natural Science Foundation of Nanjing University of Posts and Telecommunications (Grant No.NY221098)the Jiangsu Qing Lan Project for their sponsorship。
文摘This paper presents a novel view of the impact of electron collision off-axis positions on the dynamic properties and relativistic nonlinear Thomson inverse scattering of excited electrons within tightly focused, circularly polarized laser pulses of varying intensities. We examine the effects of the transverse ponderomotive force, specifically how the deviation angle and speed of electron motion are affected by the initial off-axis position of the electron and the peak amplitude of the laser pulse. When the laser pulse intensity is low, an increase in the electron's initial off-axis distance results in reduced spatial radiation power, improved collimation, super-continuum phenomena generation, red-shifting of the spectrum's harmonic peak, and significant symmetry in the radiation radial direction. However, in contradiction to conventional understandings,when the laser pulse intensity is relatively high, the properties of the relativistic nonlinear Thomson inverse scattering of the electron deviate from the central axis, changing direction in opposition to the aforementioned effects. After reaching a peak, these properties then shift again, aligning with the previous direction. The complex interplay of these effects suggests a greater nuance and intricacy in the relationship between laser pulse intensity, electron position, and scattering properties than previously thought.
基金sponsored by Insightec Co.Ltd.(Israel)China National Clinical Research Center for Geriatrics,No.NCRCG-PLAGH-2019005 (to LP)
文摘The safety and effectiveness of magnetic resonance-guided focused ultrasound thalamotomy has been broadly established and validated for the treatment of essential tremor.In 2018,the first magnetic resonance-guided focused ultrasound system in Chinese mainland was installed at the First Medical Center of the PLA General Hospital.This prospective,single center,open-label,single-arm study was part of a worldwide prospective multicenter clinical trial(ClinicalTrials.gov Identifier:NCT03253991)conducted to confirm the safety and efficacy of magnetic resonance-guided focused ultrasound for treating essential tremor in the local population.From 2019 to 2020,10 patients with medication refractory essential tremor were recruited into this open-label,single arm study.The treatment efficacy was determined using the Clinical Rating Scale for Tremor.Safety was evaluated according to the incidence and severity of adverse events.All of the subjects underwent a unilateral thalamotomy targeting the ventral intermediate nucleus.At the baseline assessment,the estimated marginal mean of the Clinical Rating Scale for Tremor total score was 58.3±3.6,and this improved after treatment to 23.1±6.4 at a 12-month follow-up assessment.A total of 50 adverse events were recorded,and 2 were defined as serious.The most common intraoperative adverse events were nausea and headache.The most frequent postoperative adverse events were paresthesia and equilibrium disorder.Most of the adverse events were mild and usually disappeared within a few days.Our findings suggest that magnetic resonance-guided focused ultrasound for the treatment of essential tremor is effective,with a good safety profile,for patients in Chinese mainland.
基金Project supported by the National Key Research and Development Program of China (Grant Nos.2020YFF01014706 and 2017YFC0601901)the National Natural Science Foundation of China (Grant Nos.61571019 and 52177026)。
文摘Josephson junction plays a key role not only in studying the basic physics of unconventional iron-based superconductors but also in realizing practical application of thin-film based devices,therefore the preparation of high-quality iron pnictide Josephson junctions is of great importance.In this work,we have successfully fabricated Josephson junctions from Co-doped BaFe_(2)As_(2)thin films using a direct junction fabrication technique which utilizes high energy focused helium ion beam(FHIB).The electrical transport properties were investigated for junctions fabricated with various He^(+)irradiation doses.The junctions show sharp superconducting transition around 24 K with a narrow transition width of 2.5 K,and a dose correlated foot-structure resistance which corresponds to the effective tuning of junction properties by He^(+)irradiation.Significant J_c suppression by more than two orders of magnitude can be achieved by increasing the He^(+)irradiation dose,which is advantageous for the realization of low noise ion pnictide thin film devices.Clear Shapiro steps are observed under 10 GHz microwave irradiation.The above results demonstrate the successful fabrication of high quality and controllable Co-doped BaFe_(2)As_(2)Josephson junction with high reproducibility using the FHIB technique,laying the foundation for future investigating the mechanism of iron-based superconductors,and also the further implementation in various superconducting electronic devices.
文摘BACKGROUND Conventional magnifying endoscopy with narrow-band imaging(NBI)observation of the gastric body mucosa shows dominant patterns in relation to the regular arrangement of collecting venules,subepithelial capillary network,and gastric pits.AIM To evaluate the effectiveness of a new one-dual(near)focus,NBI mode in the assessment of the microscopic features of gastric body mucosa compared to conventional magnification.METHODS During 2021 and 2022,68 patients underwent proximal gastrointestinal endoscopy using magnification endoscopic modalities subsequently applying acetic acid(AA).The GIF-190HQ series NBI system with dual focus capability was used for the investigation of gastric mucosa.At the time of the endoscopy,the gastric body mucosa of all enrolled patients was photographed using the white light endoscopy(WLE),near focus(NF),NF-NBI,AA-NF,and AA-NF-NBI modes.RESULTS The WLE,NF and NF-NBI endoscopic modes for all patients(204 images)were classified in the same order into three groups.Two images from each patient for the AA-NF and AA-NF-NBI endoscopic modes were classified in the same order.According to all three observers who completed the work independently,NF magnification was significantly superior to WLE(P<0.01),and the NF-NBI mode was significantly superior to NF magnification(P<0.01).After applying AA,the three observers confirmed that AA-NF-NBI was significantly superior to AA-NF(P<0.01).Interobserver kappa values for WLE were 0.609,0.704,and 0.598,respectively and were 0.600,0.721,and 0.637,respectively,for NF magnification.For the NF-NBI mode,the values were 0.378,0.471,and 0.553,respectively.For AA-NF,they were 0.453,0.603,and 0.480,respectively,and for AA-NF-NBI,they were 0.643,0.506,and 0.354,respectively.CONCLUSION When investigating gastric mucosa in microscopic detail,NF-NBI was the most powerful endoscopic mode for assessing regular arrangement of collecting venules,subepithelial capillary network,and gastric pits among the five endoscopic modalities investigated in this study.AA-NF-NBI was the most powerful endoscopic mode for analyzing crypt opening and intervening part.
文摘AIMTo evaluate intra-session repeatability and reproducibility of optical quality parameters measured at objective and subjective best focuses in a double-pass system.METHODSThirty Chinese healthy adults (19 to 40 years old) meeting our inclusion criterion were enrolled in the study. After a basic eye examination, two methods of optical quality measurement, based on subjective and objective best focuses were performed using the Optical Quality Analysis System (OQAS) with an artificial pupil diameter of 4.0 mm.RESULTSWith each method, three consecutive measurements of the following parameters: the modulation transfer function cutoff frequency (MTF<sub>cutoff</sub>), the Strehl<sup>2D</sup> ratio, the OQAS values (OVs) at contrasts of 100%, 20%, 9% and the objective scatter index (OSI) were performed by an experienced examiner. The repeatability of each method was evaluated by the repeatability limit (RL) and the coefficient of repeatability (COR). Reproducibility of the two methods was evaluated by intra-class correlation coefficient (ICC) and the 95% limits of agreement (Bland and Altman analysis). Thirty subjects, seven females and twenty three males, of whom 15 right eyes and 15 left eyes were selected randomly for recruitment in the study. The RLs (percentage) for the six parameters measured at objective focus and subjective focus ranged from 8.44% to 15.13% and 10.85% to 16.26%, respectively. The CORs for the two measurement methods ranged from 8.27% to 14.83% and 10.63% to 15.93%, respectively. With regard to reproducibility, the ICCs for the six parameters of OQAS ranged from 0.024 to 0.276. The 95% limits of agreement obtained for the six parameters (in comparison of the two methods) ranged from -0.57 to 42.18 (MTF<sub>cutoff</sub>), -0.01 to 0.23 (Strehl<sup>2D</sup> ratio), -0.02 to 1.40 (OV<sub>100%</sub>), -0.10 to 1.75 (OV<sub>20%</sub>), -0.14 to 1.80 (OV<sub>9%</sub>) and -1.46 to 0.18 (OSI).CONCLUSIONMeasurements provided by OQAS with either method showed a good repeatability. However, the results obtained from the two different measurement methods showed a poor reproducibility. These findings suggest that it might be best to evaluate patients' optical quality by OQAS using the best focus as chosen automatically by the instrument.
文摘With the global rise of industries of the new-generation information technology, energy conservation and environmental protection, biotechnology, high-end manufacturing, new materials and clean-energy vehicles, traditional metal materials cannot meet the functional requirements. Consequently, "three rare mineral resources", regarded as the best altemative for current and future new industries, have received much attention among industrial circles and have become a new focus during the present geological prospecting in China.
文摘This article analyzed the importance of information monitoring and quick response on agricultural focuses and significant events, proposed the workflow and technical framework for information monitoring and quick response based on modern information technologies, and explained key technologies during implementation and the functional structure for prototype system of the technical support platform.
基金supported by the National Natural Science Foundation of China(Grant No.51911530205)the Natural Science Foundation of Jiangsu Province(Grant No.BK20201455)+4 种基金the Guangdong Basic and Applied Basic Research Foundation(Grant No.2023A1515010890)the Key Laboratory of Port,Waterway and Sedimentation Engineering of MOT(Grant No.YK222001-2)the Open Research Fund of Key Laboratory of Water Security Guarantee in Guangdong-Hong Kong-Marco Greater Bay Area of Ministry of Water Resources(Grant No.WSGBA-KJ202309)the Qing Lan Project of Jiangsu UniversitiesThe authors also thank the Royal Society(Grant No.IEC\NSFC\181321)for providing partial support for this work。
文摘The current study investigates the hydrodynamic characteristics of gap resonance within a narrow gap formed by two adjacent boxes subjected to incident focused transient wave groups.A two-dimensional(2D)numerical wave tank based on the OpenFOAM package is utilized for this purpose.The weather-side box is fixed while the lee-side box is allowed to heave freely under wave actions.The effects of the focused wave amplitude and spectral peak period on the wave amplification within the gap,motion of the lee-side box,and wave forces(including horizontal and vertical wave forces)acting on each box are systematically examined.For comparison,another structural layout consisting of two fixed boxes is also considered.The results reveal that the release of the heave degree of freedom(DoF)of the lee-side box results in remarkably distinct resonance features.In the heave-box system,both its fluid resonant period and the period corresponding to the maximum heave displacement of the lee-side box are significantly larger(i.e.,1.6-1.7 times)than the fluid resonant period of the fixed-box system.However,the wave amplification factor inside the gap in the heave-box system is significantly lower than that in the fixed-box one.Both the variations of the maximum horizontal and vertical wave forces with the spectral peak period and their magnitudes are also significantly different between the two structural systems.
基金supported by the National Key Research and Development Program of China(2019YFA0705000,2022YFA1404800)National Natural Science Foundation of China(12004221,12174107,12192254,11734009,12192251,92250304,11974218)+4 种基金Postdoctoral Innovation Talents Support Program of Shandong Province(No.SDBX2019005)Science and Technology Commission of Shanghai Municipality(21DZ1101500)Local science and technology development project of the central government(YDZX20203700001766)Shanghai Municipal Science and Technology Major ProjectNatural Science Foundation of Shandong Province(ZR2021ZD02).
文摘To improve the processing efficiency and extend the tuning range of 3D isotropic fabrication,we apply the simultaneous spatiotemporal focusing(SSTF)technique to a high-repetition-rate femtosecond(fs)fiber laser system.In the SSTF scheme,we propose a pulse compensation scheme for the fiber laser with a narrow spectral bandwidth by building an extra-cavity pulse stretcher.We further demonstrate truly 3D isotropic microfabrication in photosensitive glass with a tunable resolution ranging from 8μm to 22μm using the SSTF of fs laser pulses.Moreover,we systematically investigate the influences of pulse energy,writing speed,processing depth,and spherical aberration on the fabrication resolution.As a proof-of-concept demonstration,the SSTF scheme was further employed for the fs laser-assisted etching of complicated glass microfluidic structures with 3D uniform sizes.The developed technique can be extended to many applications such as advanced photonics,3D biomimetic printing,micro-electromechanical systems,and lab-on-a-chips.
文摘On November 5-11,China hosted the 2014 APEC Economic Leaders’Week in Beijing.China’s Foreign Trade invited three experts focusing on APEC issues to share their thoughts on this year’s APEC meeting.1 What do you think of the meaning and impact of China’s holding APEC meeting this year?2 As we know,this theme of the summit is"Shaping the future through Asia-Pacific Partnership".There are three important issues of