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基于Linkage Mapper的武汉市生态安全格局构建
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作者 严定华 周翔 +2 位作者 包丽艳 杨恩蕾 王鹏程 《城市建筑》 2024年第19期28-33,60,共7页
城市蓝绿空间对维持城市生态平衡具有重要作用,城市化的快速发展促使生态用地破碎化。文章以武汉市为研究对象,基于“生态源地识别—阻力面构建—生态廊道识别—战略节点识别”框架结合连通性构建生态安全格局。结果表明:①生态源地面积... 城市蓝绿空间对维持城市生态平衡具有重要作用,城市化的快速发展促使生态用地破碎化。文章以武汉市为研究对象,基于“生态源地识别—阻力面构建—生态廊道识别—战略节点识别”框架结合连通性构建生态安全格局。结果表明:①生态源地面积共3053.09 km^(2),空间上多集中于武汉市西北部、东南部和东北部。②阻力因子的选取包括土地利用、地形、人为干扰及生态保护四个方面,运用层次分析法得到各阻力因子权重分别为0.387、0.316、0.109和0.188,结合ArcGIS加权得到综合生态阻力值,在空间上呈现“中间高、四周低”的特征。③基于Linkage Mapper识别出生态廊道21条,共计1223.72 km,生态网络结构α指数为0.43、β指数为1.62、γ指数为0.64,重力模型筛选出的作用力大于15的一级廊道共8条。④识别出548个生态夹点,总面积2.7801 km2;473处生态障碍点,总面积8.874 km2。 展开更多
关键词 linkage Mapper 生态安全格局 重力模型 MSPA
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The Interventional Capacity of Community Health Volunteers for Screening and Linkages of Non-Communicable Diseases in Nyeri County, Kenya
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作者 Kenneth Mugambi Jackline Nyaberi Elizabeth Echoka 《Open Journal of Preventive Medicine》 2024年第4期61-78,共18页
Non-communicable diseases (NCDs) account for 63% of mortalities. Approximately 80% of these NCD-related deaths occur in LMICs. A quasi-experimental study utilizing a non-equivalent pre-and post-test was conducted from... Non-communicable diseases (NCDs) account for 63% of mortalities. Approximately 80% of these NCD-related deaths occur in LMICs. A quasi-experimental study utilizing a non-equivalent pre-and post-test was conducted from May 2022 to March 2023 with 370 study participants. Multistage cluster and random sampling were used to select ten community units, and therefore, 150 CHVs were chosen for the control unit, and 150 were used to form the interventional group. Data was collected from the KOBO app. Six (6) homogenous FGDs comprised ten members, and 10 KII were conducted across study sites. Quantitative data was analyzed using SPSS version 28.0, and qualitative data was audio-recorded, transcribed, and analyzed via N-Vivo 12. The study shows that 59.3% of respondents have minimal information, and 92.7% (n = 139) have no clear understanding of NCDs, with a pre-intervention capacity of 48.8%. Independent sample t-test showed a significant difference in capacity from a pre-intervention average of 48.75 (SD ± 5.7)%, which increased to 68.28 (SD ± 7.6)%, p < 0.001. A well-designed community interventional model plays a pivotal role in grassroots healthcare delivery but requires optimization for NCD management. 展开更多
关键词 INTERVENTION Community Health Volunteers Non-Communicable Disease SCREENING linkages
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Chronic Hepatitis B in Indian Americans: Lack of Screening and Poor Linkage to Care
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作者 Chul Hyun Soonsik Kim +4 位作者 Emily Li Minhee Lee Mitchell K. Spinnell Joseph McMenamin Dohyun Cho 《International Journal of Clinical Medicine》 CAS 2024年第4期197-209,共13页
Background: Chronic hepatitis B (CHB) is a major cause of liver-related morbidity and mortality in the United States (US) and globally. CHB disproportionately affects Asian Americans and many other immigrant minority ... Background: Chronic hepatitis B (CHB) is a major cause of liver-related morbidity and mortality in the United States (US) and globally. CHB disproportionately affects Asian Americans and many other immigrant minority populations, primarily owing to the high prevalence of CHB in their countries of origin. India is a country with a medium-to-high prevalence of hepatitis B (HB) (>2%) and has over 40 million people infected with hepatitis B virus (HBV), with more than 115,000 deaths annually from HBV-related complications. Indian Americans are one of the largest immigrant populations in the US but remain underdiagnosed and poorly linked to clinical care. We, therefore, assessed the HBV prevalence and evaluated the linkage-to-care (LTC) among Indian Americans to develop strategic plans to reduce the impact of HBV in the US. Methods: Between April 2022 and January 2024, serologic screening and surveys were provided to 328 Indian American adults (age 20 - 80) in New York City. All participants were tested for a triple panel consisting of hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), and hepatitis B core IgG antibody (anti-HBc). A survey was conducted on the subjects chronically infected with HBV regarding their histories of infection. Self-administered questionnaires were employed to evaluate demographic and epidemiologic characteristics. Results: Of 328 screened and evaluated (246 males and 82 females), 10 (3.0%) were HBV-infected, 222 (67.7%) were susceptible to HBV, and 96 (29.3%) were immune. The prevalence of chronic HBV varied between the age groups: 4.6% (age 20 - 40), 3.4% (age 41 - 60), and 1.7% (age 61 - 80). Of 10 chronically infected, only two subjects had been previously diagnosed but were not engaged in care. Conclusion: HBV disproportionately affects Asian Americans, primarily owing to immigration from parts of the world where the disease is endemic. Indian Americans belong to an intermediate-risk group, with an HBV prevalence of >2%, but remain underdiagnosed and poorly linked to care. Our pilot study on Indian American populations, the first of its kind, demonstrates a 3% prevalence of CHB, none of whom are linked to care. In addition, this population has a high percentage of unimmune subjects, creating a large reservoir for future infection. With the growing population of Indian Americans, our findings can be used to develop community-based strategies for HBV screenings and LTC that target high-risk groups. 展开更多
关键词 Hepatitis B Virus Chronic Hepatitis B Indian Americans Health Disparity Community-Based Screening linkage-to-Care
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基于MSPA-Linkage Mapper的福州滨海长乐区生态网络构建与优化 被引量:4
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作者 廖剑威 闫淑君 +3 位作者 叶佳伟 杨丽 纪霜 尤泽欣 《西北林学院学报》 CSCD 北大核心 2023年第5期243-251,共9页
构建生态网络是改善城市生态环境和维持生态服务功能的重要举措。以福州市长乐区为例,基于形态空间格局(MSPA)、Linkage Mapper和重力模型提取各级潜在生态廊道及生态节点,构建并优化长乐区生态网络。结果表明:1)基于MSPA识别出所有景... 构建生态网络是改善城市生态环境和维持生态服务功能的重要举措。以福州市长乐区为例,基于形态空间格局(MSPA)、Linkage Mapper和重力模型提取各级潜在生态廊道及生态节点,构建并优化长乐区生态网络。结果表明:1)基于MSPA识别出所有景观类型,核心区面积最大(245.36 km^(2)),占所有景观类型的73.61%,结合核心源地连通性评价,筛选出11个核心生态源地;2)通过Linkage Mapper、重力模型提取研究区潜在生态廊道共32条,1级廊道11条,2级廊道10条,3级廊道11条,主要分布在研究区南北部纵向连接,尚未形成整体的网络连接;3)采用Barrier Mapper、Pinch point综合识别生态节点,1级生态节点17个,2级生态节点12个、3级生态节点8个,确定各类型生态修复关键区域,提出生态暂歇点建设策略。研究结果为长乐区域生态可持续发展及建设生态保护重点区时序性研究提供参考意义。 展开更多
关键词 生态廊道 形态学空间格局(MSPA) linkage Mapper 生态网络 生态节点
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基于Linkage Mapper与复杂网络的成都市生态网络构建与优化 被引量:5
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作者 田硕娟 张文君 +2 位作者 何灵 缪骏懿 訾应昆 《西北林学院学报》 CSCD 北大核心 2023年第3期176-184,共9页
城市化速度加快,城镇内部生态斑块破碎,生态廊道隔断,区域可持续发展受到阻碍。构建生态网络可以连接破碎斑块,保护生物多样性与地域特色。以成都市为例,基于形态学空间格局分析(morphological spatial pattern analysis, MSPA)方法并... 城市化速度加快,城镇内部生态斑块破碎,生态廊道隔断,区域可持续发展受到阻碍。构建生态网络可以连接破碎斑块,保护生物多样性与地域特色。以成都市为例,基于形态学空间格局分析(morphological spatial pattern analysis, MSPA)方法并结合景观连通度指数确定生态源地,从地形、景观结构、人类活动三方面确定阻力因子来构建综合阻力面,基于ArcGIS水文分析原理和linkageMapper识别生态廊道和生态节点,利用复杂网络增边优化理论,对研究区处于高阻力值且介中心性低的点进行模拟增边,最后对比增边前后的稳定性,验证增边效果。结果表明:1)成都市生态源地主要分布在西部林区,东部和中部较为稀疏。2)成都市阻力值呈现由中部向外部降低趋势,中心都市圈阻力值最高。3)基于GIS共提取111条生态廊道、209条辐射道、101个生态节点。4)识别出增边优化节点8个,成功模拟增加11条生态廊道,模拟增边优化后网络稳定性明显提升,网络连通性增强,网络结构整体更为稳定。 展开更多
关键词 生态廊道 生态节点 生态网络 linkage Mapper(LM) 复杂网络 稳定性
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Effect of internet multiple linkage mode-based extended care combined with in-hospital comfort care on colorectal cancer patients undergoing colostomy 被引量:1
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作者 Li Xu Mei-Zhen Zhou 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第9期1959-1968,共10页
BACKGROUND Patients with colorectal cancer may need postoperative nursing to improve prognosis,and conventional nursing is not effective.Clinical research is needed to explore nursing methods that can more effectively... BACKGROUND Patients with colorectal cancer may need postoperative nursing to improve prognosis,and conventional nursing is not effective.Clinical research is needed to explore nursing methods that can more effectively improve postoperative conditions on colorectal cancer patients undergoing colostomy.AIM To explore the effect of internet multiple linkage mode-based extended care combined with in-hospital comfort care on colorectal cancer patients undergoing colostomy.METHODS Data from 187 patients with colostomy treated in our hospital from May 2019 to March 2022 were collected and divided into three groups,A(n=62),B(n=62)and C(n=63),according to different intervention methods.Group A received internet multiple linkage mode-based extended care combined with in-hospital comfort care.Group B received internet multiple linkage mode-based extended care.Group C received usual care intervention.Complications were compared among the three groups.The stoma self-efficacy scale,Hamilton Anxiety Scale,RESULTS The complication rate of group A,B and C(16.13%,20.97%and 60.32%,respectively)was significantly different(all P<0.05).The incidence of complications in groups A and B was lower than that in group C,and there was no significant difference between groups A and B(P>0.05).After intervention,the scores of ostomy care,social contact,diet choice,confidence in maintaining vitality,confidence in self-care of ostomy,confidence in sexual life,confidence in sexual satisfaction and confidence in physical labor in the three groups were all higher than before intervention,and the scores of groups A and B were higher than those of group C,with statistical significance(P<0.05).The Hamilton Anxiety Scale and Hamilton Depression Scale scores of the three groups after intervention were lower than those before intervention.The scores of groups A and B were lower than those of group C,and the score of group A was lower than that of group B,all with statistical significance(all P<0.05).There was a statist-ically significant difference in cancer-induced fatigue among the three groups(P<0.05).After intervention,the scores of physical health,psychological health,social health and mental health of the three groups were lower than before the intervention.The scores of group A and B were lower than that of group C;and the score of group A was lower than that of group B,all with statistical significance(all P<0.05).CONCLUSION Internet multiple linkage mode-based extended care combined with in-hospital comfort care can effectively improve self-efficacy,bad mood,cancer-related fatigue and life quality of colorectal cancer patients undergoing colostomy. 展开更多
关键词 Internet multiple linkage mode Extended care In-hospital comfort care Colorectal cancer patients Patients undergoing colostomy
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Fragmentation stability and retention time-shift obtained by LC-MS/MS to distinguish sialylated N-glycan linkage isomers in therapeutic glycoproteins
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作者 Chi Soo Park Minju Kang +7 位作者 Ahyeon Kim Chulmin Moon Mirae Kim Jieun Kim Subin Yang Leeseul Jang Ji Yeon Jang Ha Hyung Kim 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2023年第3期305-314,共10页
Sialylated N-glycan isomers withα2-3 orα2-6 linkage(s)have distinctive roles in glycoproteins,but are difficult to distinguish.Wild-type(WT)and glycoengineered(mutant)therapeutic glycoproteins,cytotoxic T lymphocyte... Sialylated N-glycan isomers withα2-3 orα2-6 linkage(s)have distinctive roles in glycoproteins,but are difficult to distinguish.Wild-type(WT)and glycoengineered(mutant)therapeutic glycoproteins,cytotoxic T lymphocyte-associated antigen-4-immunoglobulin(CTLA4-Ig),were produced in Chinese hamster ovary cell lines;however,their linkage isomers have not been reported.In this study,N-glycans of CTLA4-Igs were released,labeled with procainamide,and analyzed by liquid chromatography-tandem mass spectrometry(MS/MS)to identify and quantify sialylated N-glycan linkage isomers.The linkage isomers were distinguished by comparison of 1)intensity of the N-acetylglucosamine ion to the sialic acid ion(Ln/Nn)using different fragmentation stability in MS/MS spectra and 2)retention time-shift for a selective m/z value in the extracted ion chromatogram.Each isomer was distinctively identified,and each quantity(>0.1%)was obtained relative to the total N-glycans(100%)for all observed ionization states.Twenty sialylated N-glycan isomers with onlyα2-3 linkage(s)in WT were identified,and each isomer's sum of quantities was 50.4%.Furthermore,39 sialylated N-glycan isomers(58.8%)in mono-(3 N-glycans;0.9%),bi-(18;48.3%),tri-(14;8.9%),and tetra-(4;0.7%)antennary structures of mutant were obtained,which comprised mono-(15 N-glycans;25.4%),di-(15;28.4%),tri-(8;4.8%),and tetra-(1;0.2%)sialylation,respectively,with onlyα2-3(10 N-glycans;4.8%),bothα2-3 andα2-6(14;18.4%),and onlyα2-6(15;35.6%)linkage(s).These results are consistent with those forα2-3 neuraminidase-treated N-glycans.This study generated a novel plot of Ln/Nn versus retention time to distinguish sialylated N-glycan linkage isomers in glycoprotein. 展开更多
关键词 Therapeutic glycoprotein SIALYLATION linkage isomer LC-MS/MS
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Construction of a high-density SSR genetic linkage map and identification of QTL for storage-root yield and dry-matter content in sweetpotato
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作者 Chenxing Zheng Zhicheng Jiang +8 位作者 Yusha Meng Jun Yu Xinsun Yang Huan Zhang Ning Zhao Shaozhen He Shaopei Gao Hong Zhai Qingchang Liu 《The Crop Journal》 SCIE CSCD 2023年第3期963-967,共5页
Sweetpotato(Ipomoea batatas(L.)Lam.)is a widely grown food crop especially in developing countries.Increasing storage-root yield and dry-matter content has been the main breeding objective of the crop,and DNA marker-a... Sweetpotato(Ipomoea batatas(L.)Lam.)is a widely grown food crop especially in developing countries.Increasing storage-root yield and dry-matter content has been the main breeding objective of the crop,and DNA marker-assisted breeding is needed for this purpose.In this study,using a mapping population of 500 F1 individuals from a cross between Xushu 18(female)and Xu 781(male),we constructed a highdensity genetic linkage map of sweetpotato using 601 simple-sequence repeat(SSR)primer pairs.The Xushu 18 map contained 90 linkage groups with 5547 SSR markers and spanned 18,263.5 cM,and the Xu 781 map contained 90 linkage groups with 4599 SSR markers and spanned 18,043.7 cM,representing the highest genome coverage yet reported for sweetpotato.We identified 33 QTL for storage-root yield and 16 QTL for dry-matter content,explaining respectively 6.5%–47.5%and 3.2%–18.9%of variation.These results provide a foundation for fine-mapping and cloning of QTL and for marker-assisted breeding in sweetpotato. 展开更多
关键词 SWEETPOTATO SSR linkage map QTL Storage-root yield Dry-matter content
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Identification of the candidate gene controlling tiller angle in common wheat through genome-wide association study and linkage analysis
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作者 Lei Zhao Canguan Wang +11 位作者 Tongzhu Wang Jinyuan Liu Qi Qiao Yulu Yang Pengyu Hu Leilei Zhang Simin Zhao Daiying Chen Yan Ren Ning Zhang Zhongdong Dong Feng Chen 《The Crop Journal》 SCIE CSCD 2023年第3期870-877,共8页
Wheat tiller angle(TA)is an important agronomic trait that contributes to grain production by affecting plant architecture.It also plays a crucial role in high-yield wheat breeding.An association panel and a recombina... Wheat tiller angle(TA)is an important agronomic trait that contributes to grain production by affecting plant architecture.It also plays a crucial role in high-yield wheat breeding.An association panel and a recombinant inbred line(RIL)population were used to map quantitative trait loci(QTL)for TA.Results showed that 470 significant SNPs with 10.4%–28.8%phenotypic variance explained(PVE)were detected in four replicates by a genome-wide association study(GWAS).Haplotype analysis showed that the TA_Hap_4B1 locus on chromosome 4B was a major QTL to regulate wheat TA.Ten QTL were totally detected by linkage mapping with the RIL population,and QTA.hau-4B.1 identified in six environments with the PVE of 7.88%–18.82%was a major and stable QTL.A combined analysis demonstrated that both TA_Hap_4B1 and QTA.hau-4B.1 were co-located on the same region.Moreover,QTA.hau-4B.1 was confirmed by bulked segregant RNA-Seq(BSR-Seq)analysis.Phenotypic analysis showed that QTA.hau-4B.1was also closely related to yield traits.Furthermore,Traes CS4B02G049700 was considered as a candidate gene through analysis of gene sequence and expression.This study can be potentially used in cloning key genes modulating wheat tillering and provides valuable genetic resources for improvement of wheat plant architecture. 展开更多
关键词 Common wheat Tiller angle GWAS linkage mapping Plant architecture
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Study on the disaster caused by the linkage failure of the residual coal pillar and rock stratum during multiple coal seam mining:mechanism of progressive and dynamic failure
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作者 Yunliang Tan Qing Ma +4 位作者 Xiaoli Liu Xuesheng Liu Derek Elsworth Ruipengg Qian Junlong Shang 《International Journal of Coal Science & Technology》 EI CAS CSCD 2023年第3期122-135,共14页
Multi-seam mining often leads to the retention of a significant number of coal pillars for purposes such as protection,safety,or water isolation.However,stress concentration beneath these residual coal pillars can sig... Multi-seam mining often leads to the retention of a significant number of coal pillars for purposes such as protection,safety,or water isolation.However,stress concentration beneath these residual coal pillars can significantly impact their strength and stability when mining below them,potentially leading to hydraulic support failure,surface subsidence,and rock bursting.To address this issue,the linkage between the failure and instability of residual coal pillars and rock strata during multi-seam mining is examined in this study.Key controls include residual pillar spalling,safety factor(f.),local mine stiffness(LMS),and the post-peak stiffness(k)of the residual coal pillar.Limits separating the two forms of failure,progressive versus dynamic,are defined.Progressive failure results at lower stresses when the coal pillar transitions from indefinitely stable(f,>1.5)to failing(f,<1.5)when the coal pillar can no longer remain stable for an extended duration,whereas sud-den(unstable)failure results when the strength of the pillar is further degraded and fails.The transition in mode of failure is defined by the LMS/k ratio.Failure transitions from quiescent to dynamic as LMS/k.<1,which can cause chain pillar instability propagating throughout the mine.This study provides theoretical guidance to define this limit to instability of residual coal pillars for multi-seam mining in similar mines. 展开更多
关键词 Multi-seam mining Residual coal pillars Rock stratum linkage instability mechanism Local mine stiffness
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Genetic linkage mapping and QTL identification for salinity tolerance in Indian mustard(Brassica juncea L.Czern and Coss.)using SSR markers
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作者 Rekha Patel Sumit Jangra +2 位作者 Ram Avtar Neelam R.Yadav Ram C.Yadav 《Oil Crop Science》 CSCD 2023年第3期191-205,共15页
Soil salinity is one of the major environmental constraints that limits crop yield and nearly 7%of the total area worldwide is affected by salinity.Salinity-induced oxidative stress causes membrane damage during germi... Soil salinity is one of the major environmental constraints that limits crop yield and nearly 7%of the total area worldwide is affected by salinity.Salinity-induced oxidative stress causes membrane damage during germination and seedling growth.Indian mustard is a major oilseed crop in India and its production and productivity are severely affected by salt stress.Breeding Brassica cultivars for salinity tolerance by conventional means is very difficult and time-consuming.Therefore,understanding the molecular components associated with salt tolerance is needed to facilitate breeding for salt tolerance in Brassica.In this investigation,quantitative trait loci(QTLs)associated with salt tolerance were identified using F_(2:3)mapping population developed from a cross between CS52(salinity tolerant)and RH30(salinity sensitive).Parents and F_(2:3)were evaluated under controlled and salinity stress conditions for 14 morpho-physiological traits for two consecutive generations(F2 and F_(2:3)),explaining proportion of the phenotypic variance under control condition.Simple sequence repeat(SSR)markers were used for mapping studies.A genetic linkage map based on 42 simple sequence repeats(SSRs)markers was constructed covering 2298.5 cM(Haldane)to identify the loci associated with salt tolerance in Brassica juncea.Forty-one SSRs showing polymorphism in the parents(CS52 and RH30)were mapped on 8 linkage groups(C1–C8).One marker(nga 129)did not map to any of the linkage group and was excluded from mapping.Linkage group 5(C5;317.9 cM)was longest and linkage group 1(C1,255.0 cM)was shortest.Further,we identified 15 QTLs controlling 8 traits using F_(2:3)population.These QTLs explained 12.44–60.63%of the phenotypic variation with a LOD score range of 3.62–5.97.Out of these QTLs,QMI4.1 related to membrane injury showed 51.28%phenotypic variance with a LOD score of 3.34.QTL QBYP8.1 related to biological yield per plant showed 60.63%phenotypic variance at a LOD score of 3.62.The highest LOD score of 5.97 was recorded for QTL related to seed yield per plant(QSYP4.1).Major QTLs were QTL for biological yield per plant(QBYP8.1),QTL for siliquae per plant(QSP4.1),QTL for primary branches(QPB4.1),QTLs for seed per siliqua(QSS4.1,QSS4.2),QTL for seed yield per plant(QSYP4.1),and QTL for membrane injury(QMI8.1)which showed more than 50%phenotypic variance.These QTLs identified in our study need to be confirmed in other populations as well so that these can be used in marker-assisted selection and breeding to enhance salt tolerance in Brassica juncea. 展开更多
关键词 Brassica juncea Salt stress tolerance SSR markers linkage mapping QTL identification
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A Study on the Interest Linkage Mechanism of the Taxus Industry Chain in Pengshui Miao and Tujia Autonomous County
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作者 Zhengchun WANG Guifang CHEN +4 位作者 Haiyan JIANG Guohao ZHANG Yan TIAN Jing XIN Jihui LI 《Agricultural Biotechnology》 CAS 2023年第5期22-25,共4页
At the Taxus base of Pengshui Miao and Tujia Autonomous County,Chongqing,the comprehensive development and utilization of Taxus was carried out with seedling cultivation,understory economy,product processing,ecotouris... At the Taxus base of Pengshui Miao and Tujia Autonomous County,Chongqing,the comprehensive development and utilization of Taxus was carried out with seedling cultivation,understory economy,product processing,ecotourism and other aspects as the main line.The benefit linkage mechanism of the operation of the Taxus industrial chain was explored and analyzed,so as to extend and supplement the Taxus industrial chain.The two models of"company+farmer"and"company+village collective+farmer"are relatively close benefit linkage models,which indirectly promote the increase of farmers income and smoothly guarantee the operation of the industrial chain,thereby playing a positive role during the development of the Taxus industry.This study provides reliable countermeasures and suggestions for the sustained and healthy development of the Taxus industry in Pengshui County. 展开更多
关键词 TAXUS Development and utilization Industrial chain Interest linkage Mechanism
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Evolution of economic linkage network of the cities and counties on the northern slope of the Tianshan Mountains,China
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作者 YANG Zeyu ZHANG Shubao +4 位作者 LEI Jun ZHANG Xiaolei TONG Yanjun DUAN Zuliang FAN Liqin 《Regional Sustainability》 2023年第2期173-184,共12页
The exchanges between cities and counties in the northern slope economic belt of Tianshan Mountains(NSEBTM)are increasingly frequent and the economic linkages are increasingly close,but the spatial distribution of eco... The exchanges between cities and counties in the northern slope economic belt of Tianshan Mountains(NSEBTM)are increasingly frequent and the economic linkages are increasingly close,but the spatial distribution of economic development and linkages among the cities and counties within NSEBTM is uneven.Therefore,it is of great significance to study the evolution of spatial-temporal pattern of the economic linkage network of cities and counties on NSEBTM to promote the coordinated and integrated development of the regional economy on NSEBTM.In this study,we used the modified gravity model and social network analysis method to analyze the spatio-temporal evolution characteristics of the economic linkage network structure of cities and counties on NSEBTM in 2000,2010,and 2020.The results showed that the comprehensive development quality level of cities and counties on NSEBTM increased from 2000 to 2020,its growth rate also increased,and its gap between cities and counties continued expanding.Both the spatial distribution patterns of the comprehensive development quality level of cities and counties on NSEBTM in 2000 and 2010 were presented as“high in the middle and low at both ends”,while the spatial distribution pattern of 2020 was exhibited as“high value and low value staggered”.The total amount of external economic linkages of cities and counties on NSEBTM showed an obvious upward trend,and its gap between cities and counties continued expanding,presenting a pattern of“a strong middle section and weak ends”.The direction of economic linkages of NSEBTM existed obvious central orientation and geographical proximity.The density of economic linkage network of NSEBTM increased from 2000 to 2020,and the structure of economic linkage network changed from single-core structure centered with Urumqi City to multicore structure centered with Urumqi City,Karamay City,Shihezi City,and Changji City,shifting from unbalanced development to balanced development.In the future,we should accelerate the construction of urban agglomeration on NSEBTM,cultivate a modern Urumqi metropolitan area,improve comprehensive development quality of the cities and counties at the eastern and western ends,strengthen the intensity of economic linkages between cities and counties,optimize the economic linkage network,and promote the coordinated and integrated development of regional economy. 展开更多
关键词 Entropy method Economic linkages Gravity model Network structure Social network analysis Northern slope economic belt of Tianshan Mountains China
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Effect Evaluation of CBL Combined with Rain Classroom Teaching Method in Medical Statistics
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作者 Man Luo Xiaofang Zhang Wei Liu 《Open Journal of Applied Sciences》 2024年第5期1204-1213,共10页
Objective: To explore the application effect of CBL combined with rain classroom teaching method in medical statistics courses. Methods: The undergraduate students of medical imaging technology in 2019 and 2020 in a u... Objective: To explore the application effect of CBL combined with rain classroom teaching method in medical statistics courses. Methods: The undergraduate students of medical imaging technology in 2019 and 2020 in a university were selected as the research objects. A cluster sampling method was used to select 79 undergraduate students from 2019 in the control group and 75 undergraduate students from 2020 in the experimental group. Traditional teaching method and CBL combined with rain classroom teaching method was used in the control group and experimental group respectively. The final examination scores of the two groups were compared. In experimental group, the correlation between the average score in the rain classroom and the final examination score was tested, and the teaching effect was evaluated. Results: The average score of final examination in experimental group and control group was 79.13 ± 10.32 points and 71.54 ± 14.752 points, respectively, which had a statistically significant difference (Z = 2.586, P = 0.012);the final examination scores of the students in the experimental group were positively correlated with the average scores of the rain classroom (r = 0.372, P = 0.001), and the proportion of satisfaction in the experimental group was 94.7%. Conclusion: The CBL combined with rain classroom teaching method can improve the teaching effectiveness of medical statistics courses. 展开更多
关键词 Rain classroom CBL Medical Statistics
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Analysis and Strategy Research on Influencing Factors of Classroom Teaching Quality in Higher Vocational Colleges
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作者 Qian Qian Wang Ma.Agatha Anne D.Dizon 《Journal of Contemporary Educational Research》 2024年第4期199-203,共5页
In this study,the questionnaire“Influencing Factors of Classroom Quality in Higher Vocational Education”was self-compiled.By using the questionnaire survey method,the research conclusion was drawn that the main fact... In this study,the questionnaire“Influencing Factors of Classroom Quality in Higher Vocational Education”was self-compiled.By using the questionnaire survey method,the research conclusion was drawn that the main factors affecting the classroom teaching quality in higher vocational education were teaching and student factors,teacher factors,and classroom factors based on 2,683 samples.According to the research results,the measures to improve the quality of classroom teaching are put forward,in order to provide guidance for improving the quality of teaching in higher vocational colleges. 展开更多
关键词 Higher vocational colleges classroom teaching quality Influencing factor
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Research and Discussion on Flipped Classroom Combined with Case-Based Learning in Pharmacoeconomics Teaching
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作者 Xingwen Zhou Zilong Dang +4 位作者 Xingdong Wang Chen Chen Zhi Rao Ting Wei Yanping Wang 《Journal of Contemporary Educational Research》 2024年第4期120-125,共6页
Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selecte... Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selected as the study subjects,and the cost-effectiveness analysis of different dosage forms of Yinzhihuang in the treatment of neonatal jaundice was selected as the teaching case.The flipped classroom combined with case-based learning teaching method was used to carry out theoretical teaching to the students.After the course,questionnaires were distributed through the Sojump platform to evaluate the teaching effect.Results:The results of the questionnaire showed that 85.71%of the students believed that the flipped classroom combined with case-based learning teaching method was helpful in mobilizing the learning enthusiasm and initiative,and improving the comprehensive application ability of the knowledge of pharmacoeconomics.92.86%of the students think that it is conducive to the understanding and memorization of learning content,as well as the cultivation of teamwork,communication,etc.Conclusion:Flipped classroom combined with case-based learning teaching method can improve students’knowledge mastery,thinking skills,and practical application skills,as well as optimize and improve teachers’teaching levels. 展开更多
关键词 Flipped classroom Case-based learning teaching method PHARMACOECONOMICS Teaching methods
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Analysis of the Application Value of Virtual Reality Combined with Flipped Classroom Teaching Mode in Cardiopulmonary Resuscitation Teaching
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作者 Hua Liu 《Journal of Contemporary Educational Research》 2024年第5期154-159,共6页
Objective:To analyze the value of using virtual reality combined with the flipped classroom teaching model in teaching cardiopulmonary resuscitation(CPR).Methods:Two classes of our nursing program were randomly select... Objective:To analyze the value of using virtual reality combined with the flipped classroom teaching model in teaching cardiopulmonary resuscitation(CPR).Methods:Two classes of our nursing program were randomly selected for the study from September 2022 to September 2023,Class A(52 students,conventional teaching method)and Class B(52 students,virtual reality combined with flipped classroom teaching mode).The assessment scores and independent learning ability scores of the students in the two classes were compared.Results:CPR theory and operation scores,passing rate,and independent learning ability scores of Class B were higher than those of Class A(P<0.05).Conclusion:the use of virtual reality combined with the flipped classroom teaching mode in CPR teaching is conducive to the improvement of students’assessment scores and independent learning ability. 展开更多
关键词 Virtual reality Flipped classroom teaching mode Cardiopulmonary resuscitation Assessment performance Independent learning ability
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Research on Practical Teaching of Ideological and Political Courses in Colleges and Universities and Collaborative Education in the Second Classroom
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作者 Luhua Xiao Pingping Liu Zimeng Li 《Journal of Contemporary Educational Research》 2024年第1期214-220,共7页
In today’s society,the need for talent training is of utmost importance due to rapid development.To achieve high-quality talent training,we need to focus on building a collaborative education mechanism.Practical teac... In today’s society,the need for talent training is of utmost importance due to rapid development.To achieve high-quality talent training,we need to focus on building a collaborative education mechanism.Practical teaching and the second classroom,which serve as important carriers of educational talents,must align their educational goals and complement each other.This article explores the collaborative education mechanism of the second classroom and practical teaching for the ideological and political courses in colleges and universities.It proposes reasonable construction measures to provide some guidelines for teaching work. 展开更多
关键词 Colleges and universities Ideological and political courses Practical teaching Second classroom Collaborative education
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Application of Cooperative Learning and Flipped Classrooms in University Basketball Courses in China
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作者 Yun-Jie Li Wan Norizan Wan Hashim Ross Azura Zahit 《Journal of Contemporary Educational Research》 2024年第6期36-43,共8页
This study investigates the application of the teaching model combining cooperative learning and flipped classrooms in university basketball courses in China.By analyzing the advantages and disadvantages of the tradit... This study investigates the application of the teaching model combining cooperative learning and flipped classrooms in university basketball courses in China.By analyzing the advantages and disadvantages of the traditional basketball teaching model and students’satisfaction with the course,the necessity of implementing cooperative learning and flipped classrooms is proposed.The study planned in detail the implementation strategies before class,in the classroom,and after class,and compared them with the control group through an experimental design.The experimental results showed that the new teaching mode demonstrated significant advantages in terms of learning outcomes,student satisfaction,and teacher evaluation.This study provides a valuable reference for the future reform of the physical education curriculum. 展开更多
关键词 Cooperative learning Flipped classroom Teaching reform Basketball course Online publication:July 3 2024
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Price linkage between Chinese and international nonferrous metals commodity markets based on VAR-DCC-GARCH models 被引量:16
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作者 岳意定 刘笃池 徐珊 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2015年第3期1020-1026,共7页
Using VAR-DCC-GARCH model,the literature on commodity price was extended by exploring the co-movement between Chinese nonferrous metal prices and global nonferrous metal prices represented by the nonferrous metal pric... Using VAR-DCC-GARCH model,the literature on commodity price was extended by exploring the co-movement between Chinese nonferrous metal prices and global nonferrous metal prices represented by the nonferrous metal prices from London Metal Exchange(LME).The results show that LME nonferrous metals prices still have a greater impact on Chinese nonferrous metals prices.However,the impact of Chinese nonferrous metals prices on LME nonferrous metals prices is still weak except for lead price.The co-movement of nonferrous metal prices between LME and China presents hysteretic nature,and it lasts for 7-8trading days.Furthermore,the co-movement between LME nonferrous metals prices and Chinese nonferrous metals prices has the characteristics of time-varying,and the correlation of lead prices between LME and China is the more stable than all other nonferrous metals prices. 展开更多
关键词 price linkage nonferrous metals commodity prices Chinese metals commodity market LME CO-MOVEMENT VAR model DCC-GARCH model
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