Dajianzhong decoction(DJZD)is one of the traditional herbal prescriptions originated from Synopsis of Golden Chamber,which clinically used for the treatment of various gastrointestinal(GI)disease.This paper was aimed ...Dajianzhong decoction(DJZD)is one of the traditional herbal prescriptions originated from Synopsis of Golden Chamber,which clinically used for the treatment of various gastrointestinal(GI)disease.This paper was aimed to provide a systematic review on the phytochemistry of DJZD and its therapeutic potential for GI disease and the mechanism.Finally,the possible development and perspectives for future research on this prescription were also discussed.To date,over 60 compounds have been identified form DJZD,including unsaturated fatty acid,saponins,and polyphenols,with hydroxy-sanshool and ginsenoside compounds as the predominant ones.DJZD possessed widely pharmacological activities on the GI disease from the Eastern Han Dynasty to the present,such as intestinal obstruction,colitis,and irritable bowel syndrome.Especially for the intestinal obstruction,it had demonstrated the efficacy of DJZD treatment for relief of postoperative ileus in patients undergoing surgery for GI cancer.The detailed mechanism was mainly related with NF-ᴋB signaling pathway.However,further research elucidating the protective effects of DJZD on GI disease,exploring new clinical effects,as well as establishing criteria for quality control for DJZD should be studied.展开更多
This study was conducted to assess the current stock of soil organic carbon under different agricultural land uses, soil types and soil depths in the Noun plain in western Cameroon. Three sites were selected for the s...This study was conducted to assess the current stock of soil organic carbon under different agricultural land uses, soil types and soil depths in the Noun plain in western Cameroon. Three sites were selected for the study, namely Mangoum, Makeka and Fossang, representative of the three dominant soil types of the noun plain (Andosols, Acrisols and Ferralsols). Three land uses were selected per site including natural vegetation, agroforest and crop field. Soil was sampled at three depths;0 - 20 cm, 20 - 40 cm, and 40 - 60 cm. Analysis of variance showed that soil type did not significantly influence carbon storage, but rather land uses and soil depth. SOCS decreased significantly with depth in all the sites, with an average stock of 66.3 ± 15.8 tC/ha at 0 - 20 cm, compared to an average stock of 33.3 ± 7.4 tC/ha at 40 - 60 cm. SOCS was significantly highest in the natural formation with 57.2 ± 19.7 tC/ha, and lowest in cultivated fields, at 37.7 ± 10.6 tC/ha. Andosols, with their high content of coarse fragments, stored less organic carbon than Ferralsols and Acrisols.展开更多
Objective:To explore the repair and treatment effect of Quan Du Zhong capsule on necrosis of femoral head in dogs.Methods:Totally 12 beagles were randomly divided into normal group,model group,Quan Du Zhong capsule gr...Objective:To explore the repair and treatment effect of Quan Du Zhong capsule on necrosis of femoral head in dogs.Methods:Totally 12 beagles were randomly divided into normal group,model group,Quan Du Zhong capsule group and Xianlinggubao capsule group,with three in each group.In addition to the normal group,the other groups established the femoral head necrosis model by liquid nitrogen alternative freezing.The normal group and the model group did not have any intervention during the modeling period,and the Quan Du Zhong group began to receive the Quan Du Zhong by gavage on the day of modeling;Xianlinggubao capsule group was given Xianlinggubao capsule by gavage once a day for 12 consecutive weeks on the day of modeling.The levels of VEGF and bFGF in the blood vessels of each group at the 12th week were compared,and the ratios of BMD,BS/BV,BV/TV,Tb.Th,Tb.N were measured by Micro CT,and the expressions of Bcl-2,Bax,Caspase-3 proteins were detected by immune reaction.Results:1.Compared with the normal group,the level of serum VEGF and bFGF in the model group decreased after 12 weeks of modeling(P<0.05);Compared with the model group,the levels of serum VEGF and bFGF water in the Xianlinggubao capsule group and the Quan Du Zhong capsule group increased on average at the 12th week of modeling,with statistical difference(P<0.05).The level of the Quan Du Zhong capsule group was the highest,followed by the Xianlinggubao capsule group.2.Compared with the normal group,BMD,BS/BV,BV/TV,Tb.Th and Tb.N in the model group were lower,and Tb.SP were higher,the results were statistically significant(P<0.05).Compared with the model group,the BMD,BV/TV,Tb.Th and Tb.N of Xianlinggubao capsule group and the total eucommia capsule group increased,while the BS/BV and Tb.SP decreased(P<0.05).3.The Quan Du Zhong capsule group and Xianlinggubao capsule group could significantly increase the expression of bcl-2 protein in the femoral head of dogs,which was significantly different from the model group(P<0.05).The expression of bax protein in the femoral head of dogs in the Quan Du Zhong capsule group and the Xianlinggubao capsule group was significantly reduced compared with the model group(P<0.05).The expression of caspase-3 protein in the femoral head of dogs was significantly reduced in the Quan Du Zhong capsule group and Xianlinggubao capsule group,which was significantly different from the model group(P<0.05).Conclusion:Quan Du Zhong capsule can increase the expression of VEGF and bFGF in serum,increase the expression of bcl-2,inhibit the expression of bax,and reduce the expression of caspase-3,which plays a synergistic role in the treatment of avascular necrosis of the femoral head,and has potential targets.展开更多
Agroforestry systems (AFSs) offer viable solutions to climate change because of the below-ground biomass (BGB) that is maintained by the soil. Therefore, spatially explicit estimation of their BGB is crucial to accoun...Agroforestry systems (AFSs) offer viable solutions to climate change because of the below-ground biomass (BGB) that is maintained by the soil. Therefore, spatially explicit estimation of their BGB is crucial to account for emission reduction efforts. A study to assess soil organic carbon (SOC) and nitrogen dynamics in Arabica coffee agroforests was conducted in two subdivisions (Foumbot and Kouoptamo) of the Noun Division in western Cameroon. The methodological approach involved the collection of 150 soil samples taken at different depths: 0 - 10, 10 - 20 and 20 - 30 cm. Depending on the depth, the SOC stock is 27.93 ± 1.13 tC/ha at 10 cm depth, 22.37 ± 1.47 tC/ha at 20 cm and 20.79 ± 0.31 tC/ha at 30 cm. According to the age classes of the Arabica coffee systems (ACA), the C/N ratio in our study area averaged 26.94 ± 13.60 for the (5 - 20) year old systems in Foumbot and 60.64 ± 48.80 for the (20 - 35) year old systems in Kouoptamo. Depending on the depth, at 10 cm this ratio is higher in Kouoptamo than in Foumbot with a maximum value of 57 and 38 respectively for the two subdivisions. In view of the results obtained, it would be important to analyse the types of microorganisms responsible for the decomposition of organic matter which is linked to soil organic carbon.展开更多
名词短语作为重要词语组合之一,在神经科学、心理学、计算机科学等领域受到广泛关注,在语言学研究领域更是持续的热点,国外相关研究从1945年以来形成了气候,但是却没有相关研究综述。因此,以Web of Science核心集为数据来源,运用文献计...名词短语作为重要词语组合之一,在神经科学、心理学、计算机科学等领域受到广泛关注,在语言学研究领域更是持续的热点,国外相关研究从1945年以来形成了气候,但是却没有相关研究综述。因此,以Web of Science核心集为数据来源,运用文献计量工具CiteSpace,从文献作者、研究机构、研究热点和前沿等方面,对1945-2022年期间关于名词短语研究的文献进行了可视化分析。研究表明:(1)国外名词短语研究广泛且分散,发文国家多,仅形成美国、英国和法国三个高中介中心型国家。中国起步晚,但发展迅速,已成为发文量前五国家之一;(2) Schriefers、Caramazza和Costa发文量多且已形成合作网络。中国作者中香港城市大学兰舸形成了一定的合作网络。Chomsky和Levelt文献影响力最大;(3)名词短语生成、词序、一致性、搭配、名词短语复杂性是名词短语研究的热门话题。高被引文献主题集中在名词短语生成和名词短语复杂性两个方面,代表名词短语研究前沿。展开更多
基金supported by National Natural Science Foundation of China(No.82304972)Shaanxi Provincial Department of Education(No.23JK0413)the Shaanxi Provincial Department of Science and Technology program(No.2024SF-YBXM-483).
文摘Dajianzhong decoction(DJZD)is one of the traditional herbal prescriptions originated from Synopsis of Golden Chamber,which clinically used for the treatment of various gastrointestinal(GI)disease.This paper was aimed to provide a systematic review on the phytochemistry of DJZD and its therapeutic potential for GI disease and the mechanism.Finally,the possible development and perspectives for future research on this prescription were also discussed.To date,over 60 compounds have been identified form DJZD,including unsaturated fatty acid,saponins,and polyphenols,with hydroxy-sanshool and ginsenoside compounds as the predominant ones.DJZD possessed widely pharmacological activities on the GI disease from the Eastern Han Dynasty to the present,such as intestinal obstruction,colitis,and irritable bowel syndrome.Especially for the intestinal obstruction,it had demonstrated the efficacy of DJZD treatment for relief of postoperative ileus in patients undergoing surgery for GI cancer.The detailed mechanism was mainly related with NF-ᴋB signaling pathway.However,further research elucidating the protective effects of DJZD on GI disease,exploring new clinical effects,as well as establishing criteria for quality control for DJZD should be studied.
文摘This study was conducted to assess the current stock of soil organic carbon under different agricultural land uses, soil types and soil depths in the Noun plain in western Cameroon. Three sites were selected for the study, namely Mangoum, Makeka and Fossang, representative of the three dominant soil types of the noun plain (Andosols, Acrisols and Ferralsols). Three land uses were selected per site including natural vegetation, agroforest and crop field. Soil was sampled at three depths;0 - 20 cm, 20 - 40 cm, and 40 - 60 cm. Analysis of variance showed that soil type did not significantly influence carbon storage, but rather land uses and soil depth. SOCS decreased significantly with depth in all the sites, with an average stock of 66.3 ± 15.8 tC/ha at 0 - 20 cm, compared to an average stock of 33.3 ± 7.4 tC/ha at 40 - 60 cm. SOCS was significantly highest in the natural formation with 57.2 ± 19.7 tC/ha, and lowest in cultivated fields, at 37.7 ± 10.6 tC/ha. Andosols, with their high content of coarse fragments, stored less organic carbon than Ferralsols and Acrisols.
基金Liaoning Provincial Science and Technology Plan Project(No.2017225043)。
文摘Objective:To explore the repair and treatment effect of Quan Du Zhong capsule on necrosis of femoral head in dogs.Methods:Totally 12 beagles were randomly divided into normal group,model group,Quan Du Zhong capsule group and Xianlinggubao capsule group,with three in each group.In addition to the normal group,the other groups established the femoral head necrosis model by liquid nitrogen alternative freezing.The normal group and the model group did not have any intervention during the modeling period,and the Quan Du Zhong group began to receive the Quan Du Zhong by gavage on the day of modeling;Xianlinggubao capsule group was given Xianlinggubao capsule by gavage once a day for 12 consecutive weeks on the day of modeling.The levels of VEGF and bFGF in the blood vessels of each group at the 12th week were compared,and the ratios of BMD,BS/BV,BV/TV,Tb.Th,Tb.N were measured by Micro CT,and the expressions of Bcl-2,Bax,Caspase-3 proteins were detected by immune reaction.Results:1.Compared with the normal group,the level of serum VEGF and bFGF in the model group decreased after 12 weeks of modeling(P<0.05);Compared with the model group,the levels of serum VEGF and bFGF water in the Xianlinggubao capsule group and the Quan Du Zhong capsule group increased on average at the 12th week of modeling,with statistical difference(P<0.05).The level of the Quan Du Zhong capsule group was the highest,followed by the Xianlinggubao capsule group.2.Compared with the normal group,BMD,BS/BV,BV/TV,Tb.Th and Tb.N in the model group were lower,and Tb.SP were higher,the results were statistically significant(P<0.05).Compared with the model group,the BMD,BV/TV,Tb.Th and Tb.N of Xianlinggubao capsule group and the total eucommia capsule group increased,while the BS/BV and Tb.SP decreased(P<0.05).3.The Quan Du Zhong capsule group and Xianlinggubao capsule group could significantly increase the expression of bcl-2 protein in the femoral head of dogs,which was significantly different from the model group(P<0.05).The expression of bax protein in the femoral head of dogs in the Quan Du Zhong capsule group and the Xianlinggubao capsule group was significantly reduced compared with the model group(P<0.05).The expression of caspase-3 protein in the femoral head of dogs was significantly reduced in the Quan Du Zhong capsule group and Xianlinggubao capsule group,which was significantly different from the model group(P<0.05).Conclusion:Quan Du Zhong capsule can increase the expression of VEGF and bFGF in serum,increase the expression of bcl-2,inhibit the expression of bax,and reduce the expression of caspase-3,which plays a synergistic role in the treatment of avascular necrosis of the femoral head,and has potential targets.
文摘Agroforestry systems (AFSs) offer viable solutions to climate change because of the below-ground biomass (BGB) that is maintained by the soil. Therefore, spatially explicit estimation of their BGB is crucial to account for emission reduction efforts. A study to assess soil organic carbon (SOC) and nitrogen dynamics in Arabica coffee agroforests was conducted in two subdivisions (Foumbot and Kouoptamo) of the Noun Division in western Cameroon. The methodological approach involved the collection of 150 soil samples taken at different depths: 0 - 10, 10 - 20 and 20 - 30 cm. Depending on the depth, the SOC stock is 27.93 ± 1.13 tC/ha at 10 cm depth, 22.37 ± 1.47 tC/ha at 20 cm and 20.79 ± 0.31 tC/ha at 30 cm. According to the age classes of the Arabica coffee systems (ACA), the C/N ratio in our study area averaged 26.94 ± 13.60 for the (5 - 20) year old systems in Foumbot and 60.64 ± 48.80 for the (20 - 35) year old systems in Kouoptamo. Depending on the depth, at 10 cm this ratio is higher in Kouoptamo than in Foumbot with a maximum value of 57 and 38 respectively for the two subdivisions. In view of the results obtained, it would be important to analyse the types of microorganisms responsible for the decomposition of organic matter which is linked to soil organic carbon.
文摘名词短语作为重要词语组合之一,在神经科学、心理学、计算机科学等领域受到广泛关注,在语言学研究领域更是持续的热点,国外相关研究从1945年以来形成了气候,但是却没有相关研究综述。因此,以Web of Science核心集为数据来源,运用文献计量工具CiteSpace,从文献作者、研究机构、研究热点和前沿等方面,对1945-2022年期间关于名词短语研究的文献进行了可视化分析。研究表明:(1)国外名词短语研究广泛且分散,发文国家多,仅形成美国、英国和法国三个高中介中心型国家。中国起步晚,但发展迅速,已成为发文量前五国家之一;(2) Schriefers、Caramazza和Costa发文量多且已形成合作网络。中国作者中香港城市大学兰舸形成了一定的合作网络。Chomsky和Levelt文献影响力最大;(3)名词短语生成、词序、一致性、搭配、名词短语复杂性是名词短语研究的热门话题。高被引文献主题集中在名词短语生成和名词短语复杂性两个方面,代表名词短语研究前沿。