Discussion on Traditional Chinese Medicine Treatment of Liver-Depression-Spleen-Deficiency Type Insomnia Based on the State-Target Theory and the Regulation of Microbiome-Gut-Brain Axis

Insomnia has become an urgent clinical problem in modern society.Current research has found that the gut flora-gut-brain axis plays an important role in regulating insomnia.The state-target theory is a product of the combination of traditional Chinese medicine and modern molecular biology technology.This paper clarifies the correlation between the state-target theory,the intestinal flora-gut-brain axis,and liver-depression-spleen-deficiency insomnia.The use of traditional Chinese medicine to regulate the structure and abundance of intestinal flora was also explored,aiming to integrate traditional Chinese medicine with Western medicine for the prevention and treatment of liver-depression-spleen-deficiency insomnia.

Analysis of feasibility of application of Beishu point acupressure therapy in treating gastroesophageal reflux disease via AMPK / ULK1 mediated autophagy pathway based on "adjusting central axis via pivot" theory

Gastroesophageal reflux disease(GERD)is a digestive system disease characterized by uncomfortable symptoms caused by reflux of gastric contents.It has increased sharply with the development of my country’s society and economy.If there is no reasonable and effective Prevention and treatment measures will inevitably increase the financial burden of patients,and also pose a major threat to the quality of life and health of patients.Cell signal transduction mediated by various receptors participates in the regulation mechanism of the body's various levels of biological functions.By inhibiting or activating its functions,the purpose of curing diseases can be achieved,and cell signal transduction has been used in traditional Chinese medicine.Studying.The theory of"adjusting the central axis"was explored by Professor Xie Sheng through decades of clinical experience.It has been proven in practice to treat GERD.It starts from the model of TCM viscera and expounds that the pathogenesis of GERD involves multiple viscera.Multi-system and multi-factor,explain the correlation of the disease with a variety of zang-fu syndromes,and use this as a basis to guide the clinical use of hidden prescriptions.The back-shu pointer therapy can prevent GERD by correcting the unbalanced state of the viscera and qi machine,and promoting the junction of the two channels of Ren and Du.Based on the theory of"adjusting the hub by the pivot",this article expounds the pathogenesis of GERD from the perspective of traditional Chinese medicine.By consulting the literature and combining with the previous research,it proposes to analyze the methods and methods of Backshu pointer therapy to prevent and treat GERD from the AMPK/ULK1 mediated autophagy pathway.

Tilted Axis Rotation of ^(57)Mn in Covariant Density Functional Theory

The self-consistent tilted axis cranking covariant density functional theory based on the point-coupling interaction is applied to investigate the tilted axis rotation in ^57 Mn. The observed data for band C are reproduced well with the assigned configuration eonfig 1. The shears mechanism for magnetic rotation is examined by investigating microscopically the orientation of angular momentum and the corresponding contributions. It is found that config 1 and config 3 correspond to a rotation of high-K character. Config 2 corresponds to a rotation of magnetic character. However, due to the presence of electromagnetic transition B（M1） and B（E2）, collective rotation plays an essential role in the competition with magnetic rotation.

IMPROVED QUANTITATIVE FEEDBACK THEORY TECHNIQUE AND APPLICATION TO THREE-AXIS HYDRAULIC SIMULATOR

In order to meet tracking performance index of three-axis hydraulic simulator, based on classical quantitative feedback theory （QFT）, an improved QFT technique is used to synthesize controller of low gain and bandwidth. By choosing a special nominal plant, the improved method assigns relative magnitude and phase tracking error between system uncertainty and nominal control plant. Relative tracking error induced by system uncertainty is transformed into sensitivity problem and relative tracking error induced by nominal plant forms into a region on Nichols chart. The two constraints further form into a combined bound which is fit for magnitude and phase loop shaping. Because of leaving out pre-filter of classical QFT controller structure, tracking performance is enhanced greatly. Furthermore, a cascaded two-loop control strategy is proposed to heighten control effect. The improved technique＇s efficacy is validated by simulation and experiment results.

Infinitely Many Solutions and a Ground-State Solution for Klein-Gordon Equation Coupled with Born-Infeld Theory

In this paper, we intend to consider a kind of nonlinear Klein-Gordon equation coupled with Born-Infeld theory. By using critical point theory and the method of Nehari manifold, we obtain two existing results of infinitely many high-energy radial solutions and a ground-state solution for this kind of system, which improve and generalize some related results in the literature.

SOLUTIONS TO DISCRETE MULTIPARAMETER PERIODIC BOUNDARY VALUE PROBLEMS INVOLVING THE p-LAPLACIAN VIA CRITICAL POINT THEORY

In this paper, we consider the existence of three nontrivial solutions for a discrete non-linear multiparameter periodic problem involving the p-Laplacian. By using the similar method for the Dirichlet boundary value problems in [C. Bonanno and P. Candito, Appl. Anal., 88（4） （2009）, pp. 605-616], we construct two new strong maximum principles and obtain that the boundary value problem has three positive solutions for λ and μ in some suitable intervals. The approaches we use are the critical point theory.

SINGULAR INTEGRAL EQUATIONS ON THE REAL AXIS WITH SOLUTIONS HAVING SINGULARITIES OF HIGHER ORDER

We transform the singular integral equations with solutions simultaneously having singularities of higher order at infinite point and at several finite points on the real axis into ones along a closed contour with solutions having singularities of higher order, and for the former obtain the extended Neother theorem of complete equation as well as the solutions and the solvable conditions of characteristic equation from the latter. The conclusions drawn by this article contain special cases discussed before.

Determination of Weak Points Based on Risk Theory and Application to Transmission Network Planning

In the traditional power transmission network planning,deterministic analysis methods are widely used.In such methods,all contingencies are deemed to have the same occurrence probability,which is not reasonable.In this paper,risk assessment is introduced to the process of transmission network planning considering the probabilistic characteristics of contingencies.Risk indices are given to determine the weak points of the transmission network based on local information,such as bus risk,line overload risk,contingency severity.The indices are calculated by the optimal cost control method based on risk theory,which can help planners to quickly determine weak points in the planning and find solution to them.For simplification,only line overload violation is considered.Finally,the proposed method is validated by an IEEE-RTS test system and a real power system in China from two aspects.In the first case,the original system is evaluated by the proposed method to find the weak points,and then four planning schemes are established,among which the best scheme is selected.In the second case,four initial planning schemes are established by combining the experiences of planners,and after the evaluation by using the proposed method,the best planning scheme is improved based on the information of weak points in the initial schemes,and the risk of improved scheme is reduced from 42 531.86 MW·h per year to 4 431.26 MW·h per year.

Stability Analysis of a Single-Degree-of Freedom Mechanical Model with Distinct Critical Points: I. Bifurcation Theory Approach

The buckling and post-buckling response of a single-degree-of-freedom mechanical model is re-examined in this work, within the context of nonlinear stability and bifurcation theory. This system has been reported in pioneer as well as in more recent literature to exhibit all kinds of distinct critical points. Its response is thoroughly discussed, the effect of all parameters involved is extensively examined, including imperfection sensitivity, and the results obtained lead to the important conclusion that the model is possibly associated with the butterfly singularity, a fact which will be validated by the contents of a companion paper, based on catastrophe theory.

QFT Robust Control Design for 3-Axis Flight Table Servo System with Large Friction

The 3-axis flight table is an important device and a typical high performanceposition and speed servo system used in the hardware-in-the-loop simulation of flight controlsystem. Friction force and uncertainty are the main characteristics in the 3-axis flight table servosystem. Based on the description of dynamic and static model of a nonlinear Stribeck frictionmodel, and taking account of the practical uncertainties of 3-axis flight table servo system, theQFT controller is designed. Simulation and realtime results are presented.

Far-field vector-diffraction of off-axis parabolic mirror under oblique incidence

Based on a full vector-diffraction theory, a detailed theoretical study is carried out, aiming at providing a clear insight into the effects of different focusing and off-axis parabola parameters on far-field vector-diffraction properties of an offaxis parabolic mirror in the presence of misalignments of the incoming beam. The physical origin of these effects is also explored. The results show that the far-field intensity profile is altered by the distortion-, coma-, and astigmatism-like aberrations, which are caused by oblique incidence rather than inherent aberrations for the off-axis configuration. The radius of 90% encircled energy also increases but does not change monotonically with incident beam size increasing, or rather,it first decreases and then increases. The focal shift strongly depends on the effective focal length and oblique incidence angle, but it is almost independent of the beam size, which affects the focusing spot patterns. The intensity distribution produces a higher astigmatic image with off-axis angle increasing. Coma-like aberration starts to become dominant with beam size increasing and results in larger curved propagation trajectory. The incident polarization also affects the intensity distribution. The variation in the Strehl ratio with oblique incidence angle strongly depends on the misalignment direction and beam size as well. In addition, we find that the difference in locus between the catacaustic and the diffraction focus in the meridian is small. But the locus of the sagittal foci is obviously different from the locus of the meridian foci and the catacaustic focus. Moreover, the peak intensity of the sagittal focus is maximum, and the ratio of the peak intensity to that in the meridian plane is approximately 1.5. Understanding these effects is valuable for assessing a practical focused intensity and describing the motion of charged particles under a strong electric field in ultraintense laser–matter interaction.

Level density of odd-A nuclei at saddle point

Based on the covariant density functional theory,by employing the core–quasiparticle coupling(CQC)model,the nuclear level density of odd-A nuclei at the saddle point is achieved.The total level density is calculated via the convolution of the intrinsic level density and the collective level density.The intrinsic level densities are obtained in the finite-temperature covariant density functional theory,which takes into account the nuclear deformation and pairing self-consistently.For saddle points on the free energy surface in the(β_(2),γ)plane,the entropy and the associated intrinsic level density are compared with those of the global minima.By introducing a quasiparticle to the two neighboring even–even core nuclei,whose properties are determined by the five-dimensional collective Hamiltonian model,the collective levels of the odd-A nuclei are obtained via the CQC model.The total level densities of the^(234-240)U agree well with the available experimental data and Hilaire’s result.Furthermore,the ratio of the total level densities at the saddle points to those at the global minima and the ratio of the total level densities to the intrinsic level densities are discussed separately.

3D face registration based on principal axis analysis and labeled regions orientation

A novel multi-view 3D face registration method based on principal axis analysis and labeled regions orientation called local orientation registration is proposed.The pre-registration is achieved by transforming the multi-pose models to the standard frontal model＇s reference frame using the principal axis analysis algorithm.Some significant feature regions, such as inner and outer canthus, nose tip vertices, are then located by using geometrical distribution characteristics.These regions are subsequently employed to compute the conversion parameters using the improved iterative closest point algorithm, and the optimal parameters are applied to complete the final registration.Experimental results implemented on the proper database demonstrate that the proposed method significantly outperforms others by achieving 1.249 and 1.910 mean root-mean-square measure with slight and large view variation models, respectively.

FIXED POINT INDEX THEORY FOR WEAKLY INWARD MAPPINGS

In this paper we define a fixed point index theory for locally Lip., completely continuous and weakly inward mappings defined on closed convex sets in general Banach spaces where no other artificial conditions are imposed. This makes ns to deal with these kinds of mappings more easily. As obvious applications, some results in [3],[5],[7],[9],[10] are deepened and extended.

Use of Rough Sets Theory in Point Cluster and River Network Selection

In this paper, we applied the rough sets to the point cluster and river network selection. In order to meet the requirements of rough sets, first, we structuralize and quantify the spatial information of objects by convex hull, triangulated irregular network (TIN), Voronoi diagram, etc.;second, we manually assign decisional attributes to the information table according to conditional attributes. In doing so, the spatial information and attribute information are integrated together to evaluate the importance of points and rivers by rough sets theory. Finally, we select the point cluster and the river network in a progressive manner. The experimental results show that our method is valid and effective. In comparison with previous work, our method has the advantage to adaptively consider the spatial and attribute information at the same time without any a priori knowledge.

Recognition Method of Aircraft Axis Direction Based on Morphological Skeleton and Hough Transform

Because of the limit of angle of view(AOV) of IR imaging seeker during the approach of missile and target, the detector can only get the partial image sequence of aircraft nose after "lose point". Recognizing the axis direction on the basis of partial IR image sequence is a key issue of the advanced IR imaging guide air-to-air missile faced. In this paper, a recognition method was proposed based on the morphological skeleton and modified Hough transform, and this method can recognize correctly the axis direction of aircraft nose in different poses during missile-target encounter. Firstly, the morphological skeleton transform was used for the extraction of skeleton features. Secondly, the modified Hough transform was used for the straight-lines detection. Finally, According to the relations between aircraft nose and axis and invariant of nose features in high-speed IR image sequence, the axis direction can be detected and calculated. Experimental results indicate that the method is feasible and effective, and the precision of axis direction recognized can meet the requirement of accurate burst control of GIF fuze.

Maximum Power Point Tracking With Fractional Order High Pass Filter for Proton Exchange Membrane Fuel Cell

Proton exchange membrane fuel cell (PEMFC) is widely recognized as a potentially renewable and green energy source based on hydrogen. Maximum power point tracking (MPPT) is one of the most important working conditions to be considered. In order to improve the performance such as convergence and robustness under disturbance and uncertainty, a fractional order high pass filter (FOHPF) is applied for the MPPT controller design based on the traditional extremum seeking control (ESC). The controller is designed with integerorder integrator (IO-I) and low pass filter (IO-LPF) together with fractional order high pass filter (FOHPF), by substituting the normal HPF in the original ESC system. With this FOHPF ESC, better convergence and smoother performance are achieved while maintaining the robust specifications. First, tracking stability is discussed under the commensurate-order condition. Then, simulation results are included to validate the proposed new FOHPF ESC scheme under disturbance. Finally, comparison results between FOHPF ESC and the traditional ESC method are also provided. © 2014 Chinese Association of Automation.

Stability Analysis of a SDOF Mechanical Model with Distinct Critical Points: II. Catastrophe Theory Approach

In a recent publication [1], the fully nonlinear stability analysis of a Single-Degree-of Freedom (SDOF) model with distinct critical points was dealt with on the basis of bifurcation theory, and it was demonstrated that this system is associated with the butterfly singularity. The present work is the companion one, tackling the problem via the Theory of Catastrophes. After Taylor expanding the original potential energy function and introducing Padè approximants of the trigonometric expression involved, the resulting truncated potential is a universal unfolding of the original one and an extended canonical form of the butterfly catastrophe potential energy function. Results in terms of equilibrium paths, bifurcation sets and manifold hyper-surface projections fully validate the whole analysis, being in excellent agreement with the findings obtained via bifurcation theory.

DEGREE THEORY FOR MULTIVALUED (S) TYPE MAPPINGS AND FIXED POINT THEOREMS

The main purpose of this paper is devoted to generalizing the results of Browder[1,2]This paper consists of four parts. In the first part, we introduce the concepts of multivalued (S) and (S), type mappings and the concepts of the limits of multivalued (S) and (S) + type mappings. These kinds of mappings contain many monotone type mappings, such as maximal monotone mapping, bounded pseudo-monotone mapping and bounded generalized pseudo-monotone mapping, as its special cases. In the second part we define the pseudo-degree for (S) type mapping and the degree for (S)+ type mapping. These two kinds of degrees are all the generalizations of the degree defined by Browder[1,2] As applications, we utilize the degree theory presented in part 2 to study the existence of solutions for the multivalued operator equations (see part 3) and to obtain some new fixed point theorems in part 4.

Axis Problem of Rough 3-Valued Algebras

The collection of all the rough sets of an approximation space has been given several algebraic interpretations, including Stone algebras, regular double Stone algebras, semi-simple Nelson algebras, pre-rough algebras and 3-valued Lukasiewicz algebras. A 3-valued Lukasiewicz algebra is a Stone algebra, a regular double Stone algebra, a semi-simple Nelson algebra, a pre-rough algebra. Thus, we call the algebra constructed by the collection of rough sets of an approximation space a rough 3-valued Lukasiewicz algebra.In this paper,the rough 3-valued Lukasiewicz algebras, which are a special kind of 3-valued Lukasiewicz algebras, are studied. Whether the rough 3-valued Lukasiewicz algebra is a axled 3-valued Lukasiewicz algebra is examined.