Application of the Concept of“Endowing the Old with the New”in Urban Renewal

The renewal of ancient cities is an important part of the urban renewal work in China.However,there are few studies on the general historical ancient cities at the county level in China,and there is no guidance on the renewal path.Through the practice of the renewal design project of Suining County,Xuzhou City,it makes an exploratory study on the renewal concept and mode.It first interprets the connotation and implementation path of the renewal concept of“endowing the old with the new”.Based on the texture analysis of the ancient city of Suining,it finally determines the design theme that tracing the historical context of the ancient city.Using the renewal techniques such as“extraction-transformationactivation”,through the renewal strategies such as“building new space,shaping new landscape,inheriting new culture and pregnant with new environment”,it realizes the regeneration of urban historical context and meets the needs of residents'modern life,so as to provide reference and guidance for the renovation of general historical ancient cities at the county level in China.

Sodium iodate induced retinal degeneration: new insights from an old model

Studies on the selective retinal degeneration induced by sodium iodate （NaIO3） date back to 1941; Sorsby （1941） described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3-induced retinal degeneration has been described in different mammalian species including sheep, rabbit, rat and mouse with varying doses and routes of administration. At the present time,

The brain-derived neurotrophic factor in neuronal plasticity and neuroregeneration: new pharmacological concepts for old and new drugs

Neurotrophins：Neurotrophins are peptides or proteins that are known to regulate neuronal viability,development,and function Beyond synaptic plasticity,neurotrophins protect neurons from apoptosis and also promote neurogenesis to recover neuronal defici even in adulthood.

Translocator protein 18 kDa(TSPO): old dogma, new mice, new structure, and new questions for neuroprotection

The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the resident immune cells and the frontline defenders responsible for the immune response of the brain. Resting microglia possess a ramified morphology with numerous thin processes that continuously sample the environment. In response to inflammatory signals, microglia become activated and transform their morphology into a thick, amoeboid-like shape. Activated microglia proliferate, tolerate to sites of iniurv,

Arginine: New and Exciting Developments for an“Old”Amino Acid

Arginine (2-amino-5-guanidino pentanoic acid) was shown in 1895 by Hedin to be present in the proteins of horn. Metabolic nitrogen balance studies, conducted in 1957 by Rose in human adults and in 1959 by Snyderman and coworkers in young infants, revealed that a dietary source of this amino acid was not an obligatory requirement for growth and maintenance of nitrogen homeostasis in healthy individuals. Hence, It was initially classified as a non-essential (dispensable) amino acid and, perhaps, for reasons of this classification arginine did not receivc the earlier atteniion it now deserves, in relation to an understanding of the nutritional biochemistry and physiology of its metabolism in humans subjects. However, there is currently a considerable interest in the cellular and tissue functions, as well as clinical, therapeutic significance, of arginine. In this paper we review the multiple functions of arginlne, including its role in the L-arginine-nitric oxide pathway,cellular regeneration, immune function, protein synthesis and protein breakdown. We then consider some in vivo aspects of the physiology of arginine metabolism, which varies greatly among eukaryotes, with particular reference to humans. Against this background, studies of arginine in the nutrition of humans under various pathophysiological conditions are reviewed briefly. Finally, a new, updated concept for the metabolic basis for the 'conditional essentiality' of arginine is proposed

Sodium glucose cotransporter-2 inhibitors: Are we targeting old devil with new problems?

Dear editor,The advent of modern molecular mechanism’s approach to disease treatment is highly advancing to mitigate/normalize the symptoms of disease i.e.hyperglycemia by targeting at least eight different pathophysiological approaches popularly known as omnious octet[1].Importantly,type 2 diabetes is a

An Understanding of Old and New Buildings in Chinese National Parks with Reference to Mount Emei

This paper presents an investigation on attitudes towards old and new buildings in Mount Emei that is a significant cultural national park in China. Questionnaires and interviews were employed to collect data from those whose careers and lives are affected, and were affected, by the buildings. The investigation reveals that people show significantly different attitudes towards the two types of buildings and place more value on old buildings. People particularise their liking for old buildings associated with traditional values, aesthetic quality and conformity to surroundings whereas indicates their disliking for new ones with changed values from tradition to modernity, unsound administrative management and poor respect for surroundings. It is concluded that traditional ideology tends to be well expressed by the old buildings but poorly by new ones. It is accordingly suggested that ideology should be taken more into account in new building projects in Mount Emei.

Old dogs with new tricks:intra-axonal translation of nuclear proteins

Many different types of polarized eukaryotic cells have been shown to segregate synthesis for some protein subpopulations to cytoplasmic domains distant from their nucleus.For neurons,these distances can be tens-to-thousands fold more than the diameter of the cell body.

Nerves and hydrogen peroxide： how old enemies become new friends

ROS and nerves play together during the regeneration process： For many years, the role of reactive oxygen species （ROS） in neurobiology has mainly focused on its pathological implications in neurodegenerative diseases. Contrasting with this view, ROS were recently put forward as key positive signals for axon growth and repair, highlighting beneficial functions of ROS signalling in the vertebrate adult brain （Borquez et al., 2016）.

OLD HOUSES IN NEW DALIAN·大连城市探珍——南山老房子测绘展

对于大连这个有百余年建市历史的城市，那些存在了八九十年的老房子无疑是见证和代表城市文化特质的珍贵财富。本次展览，源于大连理工大学建筑与艺术学院师生的周末“城市探珍”活动，旨在“发现、记录、表现、思考”正在快速消失的这部分遗产。展览以硕士研究生建筑设计课程的教学与研究成果为主线，

Does New Media Substitute Old Media? A Cohort Analysis of Media Use in China

This study examines generational differences in media use based on pooled-data analysis of CGSS(Chinese General Social Survey)2010-2015.In order to show a full picture of the substitutability between new and old media,the study brings age heterogeneity of respondents and time effect into consideration.This study distinguishes four generations based on the year of birth,with the“newspaper generation”(people who born before 1969),“broadcast generation”(1970-1979),“TV generation”(1980-1989),and“Internet generation”(born after 1990)and aims to explore whether generations differ in their frequency of media use.The research analyses five-year pooled data CGSS 2010-2015(CGSS 2014 data is missing)to examine the influence of Internet on old media among different birth cohorts and how this effect changes over time.New media refers to the Internet;old media includes newspaper,broadcast,and television.The results are summarized as follows:First,for the“newspaper generation”,“broadcast generation”,and“TV generation”,Internet heavy users are usually more willing to use newspaper and broadcast as well.Internet heavy users are information seekers.They have a strong need of information and usually are involved in multi-tasking media activities.Nevertheless,only the Internet heavy users in“TV generation”will regard TV as another channel to get more information,which indicates that generations may adopt specific patterns of media use when they are young and remain faithful to those throughout their lifespans.“TV generation”have a stronger attachment to television than their previous and later generation.Second,in terms of the time effect,the empirical data proved that the broadcast shows a stronger vitality in digital age compared with newspaper and television.The frequency of broadcast use does not drop significantly until 2015.However,the frequency of newspaper and television use has shown a significant downward trend since 2011.Third,for the“Internet generation”,the use of the Internet has no effect on the use of other media.Even Internet heavy user,the one who has strong need of information,would not choose other media to search more information.This suggests that these digital natives would rather confine themselves to the Internet cocoon than collect new information through old channels.This study provides new insight to understand the current media ecology.The relationship between the new and the old media is a changeable and dynamic process and cannot be simply understood as“more-more”or“more-less”relationship.

Xintiandi——A Perfect Blend of the Old and New

Shanghai is changing in a big way. Xintiandi-New Heaven and Earth-a development of restoredlow-rise houses called Shikumen, or "stone gate"buildings, stands as a perfect symbol of the newShanghai.

New Looks of an Old Store—Notes on China Beijing Tong Ren Tang Holdings Corp.

It is not exaggerating to say that almost everybody in China knows about Tong Ren Tang, a traditional Chinese medicine drugstore in Beijing. And even many foreigners, who have never set foot on Chinese soil, know that there is the Great Wall in China and a Tong Ren Tang in Beijing. Tong Ren Tang, which was opened in the eighth year (1669) of

The Personality Beauty Thought in New Accounts of Old Episodes

“New Accounts of Old Episodes”is a classic handed down in China,which reflects the personality image and charm of the scholars in the Wei and Jin dynasties with the original ecological narrative technique.The scholars of the Wei and Jin Dynasties were detached,facing the world with an aesthetic attitude beyond secular utilitarianism,etiquette,and real life,establish a graceful social stage of vulgarity,create a unique personality beauty,providing valuable ideological wealth for the cultivation of poetic spirit,poetic dwelling,aesthetic style,transcend personality,and wisdom.

Contrast and Comparison Between the Old and New Bar Code for Commodity Management Measures

With the development of socialism market economy, the former Bar Code ForCommodity Management Measures (being called Old Measures for short hereafter) issued by the NationalBureau of Quality and Technical Supervision can not adapt to the requirement of managing for barcode for commodity. Therefore, for the purpose of standardize bar code for commodity managementstandard, ensuring its quality, speeding up the application of it in electronic business andcirculating field and accelerating the course of being a well informed country, a new Bar Code ForCommodity Management Measures (New Measures for short) has been issued by the General Administratorof Quality Supervision, Inspection and Quarantine of P.R. China (AQSIQ) on May 30th, 2005, and putinto force in October, 2005. At the same time, the Old Measures issued on July 3rd, 1998 has beenabolished.

Old and New Tang Books on Tubo

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Pechoin: “New Concept in Old Framework”

On November 2, 2012, Pechoin won the second bidder right in 2013 The Voice of China with 70 million yuan. Together with JIA DUO BAO, the uppermost sponsor of 2013 The Voice of China, the two staged an amazing performance in which local brands defeating international brands. In the following “Double 11” Shopping Festival, Pechoin’s sales on Tmall reached over 15 million yuan only till 3 p.m. on that day, showcasing that this Chinese time-honored cosmetics brand has achieved rebirth to a large extend.