GOAL问卷和Epworth嗜睡量表联合筛查阻塞性睡眠呼吸暂停的效能

目的检验GOAL问卷和Epworth嗜睡量表(Epworth sleeping scale,ESS)在筛查阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)中联合应用的效能。方法从睡眠医学中心招募2958例参与者,完成夜间多导睡眠图监测和筛查问卷,包括GOAL、ESS、STOP-Bang问卷(SBQ)和NoSAS评分。评估每个量表的敏感度、特异度、阳性预测值、阴性预测值、诊断优势比(diagnostic odds ratio,DOR)和受试者工作特征(ROC)曲线下面积(area under the curve,AUC)。结果GOAL问卷在筛选OSA方面具有更高的敏感度和DOR(敏感度为0.831,DOR为3.72),优于STOP-Bang问卷和NoSAS评分。当GOAL问卷和ESS量表相结合时,特异度和DOR分别显著上升至0.894和4.22。GOAL问卷得分为3且ESS量表≥11分的参与者极有可能患有OSA,概率为0.96。结论GOAL问卷和ESS量表相结合具有优秀的诊断能力,可有效筛查OSA。对疑似OSA患者进行GOAL问卷后的第二阶段进行ESS量表筛查,可以提高预测准确性和早期诊断。

Synthesis and thermal characterization of the C-S-H/paraffin composite phase change material utilizing a discontinuous two-step nucleation method

The novel calcium-silicate-hydrate(C-S-H)/paraffin composite phase change materials were synthesized using a discontinuous two-step nucleation method.Initially,the C-S-H precursor is separated and dried,followed by immersion in an aqueous environment to transform it into C-S-H.This two-step nucleation approach results in C-S-H with a specific surface area of 497.2 m^(2)/g,achieved by preventing C-S-H foil overlapping and refining its pore structure.When impregnated with paraffin,the novel C-S-H/paraffin composite exhibits superior thermal properties,such as a higher potential heat value of 148.3 J/g and an encapsulation efficiency of 81.6%,outperforming conventional C-S-H.Moreover,the composite material demonstrates excellent cyclic performance,indicating its potential for building thermal storage compared to other paraffin-based composites.Compared with the conventional method,this simple technology,which only adds conversion and centrifugation steps,does not negatively impact preparation costs,the environment,and resource consumption.This study provides valuable theoretical insights for designing thermal storage concrete materials and advancing building heat management.

State of the HIV, Hepatitis B and C Virus Pandemic from 2003 to 2022 in Burkina Faso: Evolution of Prevalence Trends and Strategic Recommendations to Achieve the WHO’s Goal for Their Eradication by 2030

Background: The World Health Organization (WHO) has set a goal to eradicate or at least significantly reduce the prevalence the human immunodeficiency virus (HIV), hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) by 2030. The main objective was to provide an evolving overview of the prevalence of HIV, HBV and HCV infection between 2003 and 2022 in Burkina Faso. Methods: It was a retrospective cross-sectional study based on data from 2003 to 2022. The data were collected using information available in the databases of the HOSCO and CERBA laboratories and included all individuals who underwent HIV and/or HBV and/or HCV testing. Data analysis was performed using SPSS version 20.0, EpiInfo 7, and R version 4.1.0. Results were considered statistically significant if p Results: The study recorded 7432 samples and the mean age of the subjects was 27.98 ± 8.50 years. During this period, the respective prevalence of HIV, HBV, and HCV were 4.66% (346/7432), 8.77% (582/6636) and 5.54% (322/5816). However, from 2003 to 2022, there was a significant decrease (P y=−1.75x+12.59;y=−0.24x+10.01and y=−0.11x+6.02, with “y” corresponding to prevalence and “x” to the years. Conclusion: Burkina Faso needs to rigorously apply prevention and control strategies recommended by the WHO by 2030.

Megacity pathways in China under the dual carbon goal:The case of Shanghai

The pathways to achieving carbon neutrality at the city level are diverse due to varying energy supply and demand conditions.Shanghai faces obstacles such as limited land resources,high costs of renewable energy technologies,and instability of renewable energy.These challenges hinder the city’s efforts to achieve carbon peak and carbon neutrality(dual carbon).Therefore,Shanghai must identify and optimize its development path for renewable energy under the dual carbon goal.We employed the Low Emissions Analysis Platform Shanghai(LEAP-SH)model to simulate the impact of policies,such as industrial upgrading,energy efficiency improvement,energy structure optimization,increased technical innovation on energy,and ecological restoration,on the carbon emission pathways from 2022 to 2060 using five different scenarios.Our results indicate that Shanghai has the potential to achieve carbon neutrality in 2059 by promoting carbon reduction,pollution control,and green expansion.Moreover,we determined that the manufacturing industry;power generation industry;and transportation,storage,and mail services are the three major sectors for emission reduction under the dual carbon goal.Furthermore,the capacity and output of coal-fired power plants will be gradually replaced by offshore wind power in the dual carbon pathway.Finally,this study proposes countermeasures and suggestions for Shanghai to attain the dual carbon goal and high-quality development.

Efficient and Stable Inverted Perovskite Solar Modules Enabled by Solid-Liquid Two-Step Film Formation

A considerable efficiency gap exists between large-area perovskite solar modules and small-area perovskite solar cells.The control of forming uniform and large-area film and perovskite crystallization is still the main obstacle restricting the efficiency of PSMs.In this work,we adopted a solid-liquid two-step film formation technique,which involved the evaporation of a lead iodide film and blade coating of an organic ammonium halide solution to prepare perovskite films.This method possesses the advantages of integrating vapor deposition and solution methods,which could apply to substrates with different roughness and avoid using toxic solvents to achieve a more uniform,large-area perovskite film.Furthermore,modification of the NiO_(x)/perovskite buried interface and introduction of Urea additives were utilized to reduce interface recombination and regulate perovskite crystallization.As a result,a large-area perovskite film possessing larger grains,fewer pinholes,and reduced defects could be achieved.The inverted PSM with an active area of 61.56 cm^(2)(10×10 cm^(2)substrate)achieved a champion power conversion efficiency of 20.56%and significantly improved stability.This method suggests an innovative approach to resolving the uniformity issue associated with large-area film fabrication.

A new two-step variational model for multiplicative noise removal with applications to texture images

Multiplicative noise removal problems have attracted much attention in recent years.Unlike additive noise,multiplicative noise destroys almost all information of the original image,especially for texture images.Motivated by the TV-Stokes model,we propose a new two-step variational model to denoise the texture images corrupted by multiplicative noise with a good geometry explanation in this paper.In the first step,we convert the multiplicative denoising problem into an additive one by the logarithm transform and propagate the isophote directions in the tangential field smoothing.Once the isophote directions are constructed,an image is restored to fit the constructed directions in the second step.The existence and uniqueness of the solution to the variational problems are proved.In these two steps,we use the gradient descent method and construct finite difference schemes to solve the problems.Especially,the augmented Lagrangian method and the fast Fourier transform are adopted to accelerate the calculation.Experimental results show that the proposed model can remove the multiplicative noise efficiently and protect the texture well.

Two-step growth of β-Ga_(2)O_(3) on c-plane sapphire using MOCVD for solar-blind photodetector

In this work,a two-step metal organic chemical vapor deposition(MOCVD)method was applied for growingβ-Ga_(2)O_(3) film on c-plane sapphire.Optimized buffer layer growth temperature(T_(B))was found at 700℃ and theβ-Ga_(2)O_(3) film with full width at half maximum(FWHM)of 0.66°was achieved.A metal−semiconductor−metal(MSM)solar-blind photodetector(PD)was fabricated based on theβ-Ga_(2)O_(3) film.Ultrahigh responsivity of 1422 A/W@254 nm and photo-to-dark current ratio(PDCR)of 10^(6) at 10 V bias were obtained.The detectivity of 2.5×10^(15) Jones proved that the photodetector has outstanding performance in detecting weak signals.Moreover,the photodetector exhibited superior wavelength selectivity with rejection ratio(R_(250 nm)/R_(400 nm))of 105.These results indicate that the two-step method is a promising approach for preparation of high-qualityβ-Ga_(2)O_(3)films for high-performance solar-blind photodetectors.

The Importance of Setting Treatment Goals for Cardiovascular Diseases

Background: Guidelines are issued by most major organizations that focus on a specific disease entity. Guidelines should be a significant help to the practicing physician who may not be up-to-date with the recent medical literature. Unfortunately, when conflicting guidelines for a specific disease are published, confusion results. Purpose: This article provides a suggested guideline outcome measure that would benefit the physician and patient. Methods: A review of 19 different guidelines for cardiovascular disease treatment is one example of the lack of specific outcomes that currently exist. The basic problem with most guidelines is that they do not state the expected end result (i.e., the benefit to the patient) if that guideline is followed. When guidelines use cardiovascular disease risk factors to dictate therapy, the end benefit is never stated so that the patient can make an appropriate choice of which (if any) guideline to follow. Results: A good example is guidelines published by the American Heart Association for reducing cardiovascular disease. These guidelines are risk factor based and only indicate that cardiovascular disease would be reduced if followed. No specific percentage in the reduction of the incidence of disease is given. In contrast, when elimination of the disease is the stated goal of the guideline, the end result is clear. To date, this goal has been stated by only one organization devoted to eliminating cardiovascular disease. Conclusion: Guidelines need to be written to provide the physician and the patient with a specific end point that is expected when the guideline is followed. Patient acceptance and compliance will be much improved if the patient knows the risk/benefit of following the guideline’s recommendations.

Effect of two-step solid solution on microstructure andδphase precipitation of Inconel 718 alloy

Inconel 718 is the most popular nickel-based superalloy and is extensively used in aerospace,automotive,and energy indus-tries owing to its extraordinary thermomechanical properties.The effects of different two-step solid solution treatments on microstructure andδphase precipitation of Inconel 718 alloy were studied,and the transformation mechanism fromγ″metastable phase toδphase was clarified.The precipitates were statistically analyzed by X-ray diffractometry.The results show that theδphase content firstly increased,and then decreased with the temperature of the second-step solid solution.The changes in microstructure andδphase were studied by scanning electron microscopy and transmission electron microscopy.An intragranularδphase formed in Inconel 718 alloy at the second-[100]_(δ)[011]γ step solid solution temperature of 925℃,and its orientation relationship withγmatrix was determined as//and(010)_(δ)//(111)γ.Furthermore,the Vickers hardness of different heat treatment samples was measured,and the sample treated by second-step solid solution at 1010℃ reached the maximum hardness of HV 446.84.

Role of self-help groups on socioeconomic development and the achievement of Sustainable Development Goals(SDGs)among rural women in Cooch Behar District,India

This study examines the transformative role of self-help groups(SHGs)in the socioeconomic development of rural women in Cooch Behar District,India,and their contribution toward achieving Sustainable Development Goals(SDGs)of the United Nations.In this study,we explored the effect of SHGs on rural women by specifically addressing SDGs,such as no poverty(SDG 1),zero hunger(SDG 2),good health and well-being(SDG 3),quality education(SDG 4),and gender equality(SDG 5).Given this issue,a cross-sectional survey and comparison analyses are needed to assess the socioeconomic development of rural women and their awareness level before and after the participation of rural women in SHGs.The survey conducted as part of this study was divided into three sections,namely,demographic characteristics,socioeconomic development,and awareness level,with each focusing on different aspects.A group of 400 individuals who were part of SHGs completed the questionnaire survey form.The results showed that the participation of rural women in SHGs significantly improved their socioeconomic development and awareness level,as supported by both mean values and t test results.Memberships in SHGs and microcredit programs were the major elements that boosted the socioeconomic development of rural women,which also achieves SDGs 1,2,3,4,and 5.This study revealed that participation in SHGs and related financial services significantly aided rural women in economically disadvantaged communities in accumulating savings and initiating entrepreneurial ventures.Moreover,participation in SHGs was instrumental in enhancing the self-confidence,self-efficacy,and overall self-esteem of rural women.Finally,doing so enabled them to move more freely for work and other activities and to make family and common decisions.

Spatial differences of Sustainable Development Goals(SDGs)among counties(cities)on the northern slope of the Kunlun Mountains

The county(city)located on the northern slope of the Kunlun Mountains is the primary area to solidify and extend the success of Xinjiang Uygur Autonomous Region,China in poverty alleviation.Its Sustainable Development Goals(SDGs)are intertwined with the concerted economic and social development of Xinjiang and the objective of achieving shared prosperity within the region.This study established a sustainable development evaluation framework by selecting 15 SDGs and 20 secondary indicators from the United Nations’SDGs.The aim of this study is to quantitatively assess the progress of SDGs at the county(city)level on the northern slope of the Kunlun Mountains.The results indicate that there are substantial variations in the scores of SDGs among the nine counties and one city located on the northern slope of the Kunlun Mountains.Notable high scores of SDGs are observed in the central and eastern regions,whereas lower scores are prevalent in the western areas.The scores of SDGs,in descending order,are as follows:62.22 for Minfeng County,54.22 for Hotan City,50.21 for Qiemo County,42.54 for Moyu County,41.56 for Ruoqiang County,41.39 for Qira County,39.86 for Lop County,38.25 for Yutian County,38.10 for Pishan County,and 36.87 for Hotan County.The performances of SDGs reveal that Hotan City,Lop County,Minfeng County,and Ruoqiang County have significant sustainable development capacity because they have three or more SDGs ranked as green color.However,Hotan County,Moyu County,Qira County,and Yutian County show the poorest performance,as they lack SDGs with green color.It is important to establish and enhance mechanisms that can ensure sustained income growth among poverty alleviation beneficiaries,sustained improvement in the capacity of rural governance,and the gradual improvement of social security system.These measures will facilitate the effective implementation of SDGs.Finally,this study offers a valuable support for governmental authorities and relevant departments in their decision-making processes.In addition,these results hold significant reference value for assessing SDGs at the county(city)level,particularly in areas characterized by low levels of economic development.

Life Needs More Goals,and Fewer Complaints

In my opinion,we should have more goals in our lives and have fewer complaints.As is known to all,goals make us go further and prevent us from being lazy.When we have goals,we are encouraged to work hard to achieve them.But if we lose our goals,we may feel uncertain and insecure.For a student,goals do play an essential role in study.I once set a goal to play better in basketball games,and I tried my best to train myself without any fear and hesitation.It was the goal that helped me accomplish my ambition.

Strategies for Cultivating Public Funded Targeted Normal Students Based on Goal Management Theory : A Case Study of East, West and North Guangdong

Public funded targeted normal students are an important component of China's teacher team construction.Since its implementation in 2007,a large number of outstanding rural teachers who have been striving on the front line of education have been trained.Based on the theory of goal management,this paper explores the problems and countermeasures in the training of public funded targeted normal students.It strives to solve the problems of low willingness to teach and high default rates among public funded normal students,and hopes that the suggestions proposed in this paper can further promote the effective implementation of policies for public funded normal students.

LASG全球海洋-大气-陆面系统模式(GOALS/LASG)及其模拟研究

该文扼要介绍了ＬＡＳＧ第一版本全球海洋－大气－陆面系统模式（ＧＯＡＬＳ／ＬＡＳＧ）的发展和结构，及其对气候平均态、季节变化和年际变化的模拟，以及近期发展计划．

Novel two-step process to improve efficiency of bio-oxidation of Axi high-sulfur refractory gold concentrates

In order to improve the bio-oxidation efficiency of Axi refractory gold concentrate, a two-step process including a high temperature chemical oxidation and a subsequent bio-oxidation, combined with p H control during the bio-oxidation step was used. The results revealed that the optimum mode was to maintain solution p H at 1.0-1.2 during the biological oxidation stage. Under this condition, the activity of mixed culture could be sustained and the formation of jarosite could be diminished, thus the oxidation efficiency was improved. The oxidation levels of iron and sulfur were improved by 12.50% and 15.49%, and the gold recovery was increased by 21.02%. Therefore, the two-step process combined with p H control is an effective method for oxidizing the biohydrometallurgical process of Axi gold concentrate, and it will have a broad prospect of application in dealing with complex refractory gold concentrate.

GOALS模式对热带太平洋ENSO年际变化特征的模拟评估

文中重点分析了中国科学院大气物理研究所LASG最新发展的全球大气环流谱模式 (R4 2L9)与一全球海洋环流模式 (T6 3L30 )耦合形成的全球海洋 大气 陆面气候系统模式 (GOALS/LASG)新版本已积分 30a的模拟结果 ,通过与多种观测资料的对比分析 ,讨论了赤道太平洋海表温度 (SST)的年际变化及其纬向传播、赤道东太平洋SST异常与其他洋面SST变化之间的遥相关关系、赤道太平洋浅表层海温的年际变化特征等研究内容。结果表明 ,GOALS模式模拟出了赤道太平洋SST异常出现不规则的年际变化特点 ;赤道东太平洋SST异常的向西传播过程 ;赤道太平洋混合层海温变化由西向东、由深层向浅层的传播过程 ;同时也模拟出了赤道东太平洋SST变化与赤道西太平洋以及与西南太平洋海温之间的反相关关系 ,与南印度洋和副热带大西洋SST之间的正遥相关关系等实际观测现象。但GOALS模式也存在明显的不足 ,如对赤道东、中太平洋SST异常的年际变化幅度明显偏小 ,没能模拟出赤道东太平洋的SST变化比赤道中太平洋强的特点 ;赤道太平洋SST从东向西的传播速度明显比实际观测慢得多 ,但混合层海温极值变化由西向东的传播速度明显比实际情况快得多 ;没能模拟出赤道东太平洋SST变化同西北太平洋SST的负相关和北印度洋海温变化的正相关现象 ,因此?

Optimization of Sporulation Conditions of Biocontrol Bacteria B579 by Two-step Control Strategy

[Objective] For preparing the biopesticide of Bacillus subtilis B579 with high spore concentration,the sporulation conditions were optimized.[Method] Two-step fermentation control strategy was used,in which,the first phase（0-10 h）was to improve cell growth,and the second phase（10-30 h）was to promote spore formation.Four factors including initial glucose concentration,fermentation pH,temperature（in the second phase）and shaking speed（in the second phase）were optimized using the methods of single factor test and orthogonal experiment.[Result] The initial glucose concentration showed a significant effect on sporulation.The optimal conditions for the spore formation of B.subtilis B579 were as follows：initial glucose concentration 5 g/L,fermentation pH 7.0,the temperature for the first phase 37 ℃,and the shaking speed for the first phase 180 r/min,the temperature for the second phase 40 ℃,and the shaking speed for the second phase 200 r/min;in addition,the first phase was 10 h and the second phase of fermentation was conducted for 30 h.Under such conditions,the spore concentration and spore formation rate could reach 9.43×108 CFU/ml and 90.99%,respectively,which represented 6.70-fold and 2.43-fold increase compared with those before optimization.[Conclusion] The spores concentration of biocontrol agent was improved using two-step control strategy,which provided the basis for biopesticide production in large scale.

FLEXIBLE JOB-SHOP SCHEDULING WITH FUZZY GOAL THROUGH IOCDGA

The fuzzy goal flexible job-shop scheduling problem （FGFJSP） is the extension of FJSP. Compared with the convention JSP, it can solve the fuzzy goal problem and meet suit requirements of the key job. The multi-object problem, such as the fuzzy cost, the fuzzy due-date, and the fuzzy makespan, etc, can be solved by FGFJSP. To optimize FGFJSP, an individual optimization and colony diversity genetic algorithm （IOCDGA） is presented to accelerate the convergence speed and to avoid the earliness. In IOCDGA, the colony average distance and the colony entropy are defined after the definition of the encoding model. The colony diversity is expressed by the colony average distance and the colony entropy. The crossover probability and the mutation probability are controlled by the colony diversity. The evolution emphasizes that sigle individual or a few individuals evolve into the best in IOCDGA, but not the all in classical GA. Computational results show that the algorithm is applicable and the number of iterations is less.

Arrhenius relationship and two-step scheme in AF hyperdynamics simulation of diffusion of Mg/Zn interface

The accelerating factor （AF） method is a simple and appropriate way to investigate the atomic long-time deep diffusion at solid-solid interface. In the framework of AF hyperdynamics （HD） simulation, the relationship between the diffusion coefficient along the direction of z-axis which is normal to the Mg/Zn interface and temperature was investigated, and the AF＇s impact on the diffusion constant （D0） and activation energy （Q^＊） was studied. Then, two steps were taken to simulate the atomic diffusion process and the formation of new phases： one for acceleration and the other for equilibration. The results show that： the Arrhenius equation works well for the description of Dz with different accelerating factors; the AF has no effect on the diffusion constant Do in the case of no phase transition; and the relationship between Q＊ and Q conforms to Q^＊=Q/A. Then, the new Arrhenius equation for AFHD is successfully constructed as Dz=Doexp[-Q/（ART）]. Meanwhile, the authentic equilibrium conformations at any dynamic moment can only be reproduced by the equilibration simulation of the HD-simulated configurations. Key words： accelerating factor method; Arrhenius equation; two-steps scheme; Mg/Zn interface; hyperdynamic simulation

Goal在Agent中的使用研究综述

Agent系统是综合哲学和计算机科学等多门学科的交叉研究领域。心智模型是Agent研究中的核心问题,在各种心智模型中,最成功的是BDI模型,而Goal的引入为BDI心智模型的研究提供了新的思路。根据Goal在Agent中的特点,阐述了Goal在Agent模型中的引入、分类、语义、协商等主题,旨在总结和分析现有的Agent中Goal的使用和机制,为BDI Agent心智模型的研究和对Goal研究的发展趋势和方向提供参考。