AIM To assess the long-term prognostic value of vascular endothelial growth factor receptor 1(VEGFR1)and classⅢβ-tubulin(TUBB3)mRNA expression in nonmetastatic rectal cancer.METHODS A total of 75 consecutive patient...AIM To assess the long-term prognostic value of vascular endothelial growth factor receptor 1(VEGFR1)and classⅢβ-tubulin(TUBB3)mRNA expression in nonmetastatic rectal cancer.METHODS A total of 75 consecutive patients with non-metastatic rectal cancer from March 2004 to November 2008 were analyzed retrospectively at our institute.The mRNA expressions of VEGFR1 and TUBB3 were detected by multiplex branched DNA liquid-chip technology.The Cutoff Finder application was applied to determine cutoff point of mRNA expression.SPSS software version 22.0was used for analysis.RESULTS The median follow-up was 102.7 mo(range,6-153.6).Theχ~2 and Fisher’s exact tests showed that VEGFR1expression was related to lymph node metastasis(P=0.013),while no relationships between TUBB3 and clinicopathological features were observed.Univariate analysis showed that T stage,lymph node metastasis,tumor differentiation,VEGFR1 and TUBB3 mRNA expression were correlated to overall survival(OS)(P=0.048,P=0.003,P=0.052,P=0.003 and P=0.015,respectively).Also,lymph node metastasis and VEGFR1expression independently influenced OS by multivariate analysis(P=0.027 and P=0.033).VEGFR1 expression was positively correlated with TUBB3(P=0.024).The patients with low expression of both TUBB3 and VEGFR1 presented a better OS(P=0.003).In addition,the receiver operating characteristic analysis suggested that the combination of lymph node metastasis and VEGFR1 had a more favorable prognostic value(P<0.001).CONCLUSION VEGFR1 expression and lymph node metastasis independently and jointly affect survival.Moreover,low expression of VEGFR1 and TUBB3 presented a better OS in patients with non-metastatic rectal cancer,which might serve as a potential prognostic factor.展开更多
This paper further extends the generalized covari ant derivative from the first covariant derivative to the sec ond one on curved surfaces. Through the linear transforma tion between the first generalized covariant de...This paper further extends the generalized covari ant derivative from the first covariant derivative to the sec ond one on curved surfaces. Through the linear transforma tion between the first generalized covariant derivative and the second one, the second covariant differential transformation group is set up. Under this transformation group, the sec ond class of differential invariants and integral invariants on curved surfaces is made clear. Besides, the symmetric struc ture of the tensor analysis on curved surfaces are revealed.展开更多
In this paper we study the convergence nf a class of means on H^p(G)(0<p<1),the means take the Bochner-Riesz means in[1],the generalized Bochner-Riesz means in[2],and the operators T^(Φ_r)in[3]as special cases....In this paper we study the convergence nf a class of means on H^p(G)(0<p<1),the means take the Bochner-Riesz means in[1],the generalized Bochner-Riesz means in[2],and the operators T^(Φ_r)in[3]as special cases.We obtain weak-type estimates for the associated maximal operators and the maximal mean boundedness for the means.展开更多
A finite group G is called a Camina group if G has a proper normal subgroup N such that gN is precisely a conjugacy class of G for any g ∈E G - N. In this paper, the structure of a Camina group G is determined when N...A finite group G is called a Camina group if G has a proper normal subgroup N such that gN is precisely a conjugacy class of G for any g ∈E G - N. In this paper, the structure of a Camina group G is determined when N is a union of 2, 3 or 4 conjugacy classes of G.展开更多
Quadratic-field cryptosystem is a cryptosystem built from discrete logarithm problem in ideal class groups of quadratic fields(CL-DLP). The problem on digital signature scheme based on ideal class groups of quadratic ...Quadratic-field cryptosystem is a cryptosystem built from discrete logarithm problem in ideal class groups of quadratic fields(CL-DLP). The problem on digital signature scheme based on ideal class groups of quadratic fields remained open, because of the difficulty of computing class numbers of quadratic fields. In this paper, according to our researches on quadratic fields, we construct the first digital signature scheme in ideal class groups of quadratic fields, using q as modulus, which denotes the prime divisors of ideal class numbers of quadratic fields. Security of the new signature scheme is based fully on CL-DLP. This paper also investigates realization of the scheme, and proposes the concrete technique. In addition, the technique introduced in the paper can be utilized to realize signature schemes of other kinds.展开更多
Let G be a finite group with the property that for any conjugacy class order, G has exactly two conjugacy classes which have the same order. We prove that： （1） ff a Sylow 2-subgroup of G is Abelian, then G is isomo...Let G be a finite group with the property that for any conjugacy class order, G has exactly two conjugacy classes which have the same order. We prove that： （1） ff a Sylow 2-subgroup of G is Abelian, then G is isomorphic to the direct product of symmetric group with order 3 and cyclic group with order 2, or G is isomorphic to the semidirect product of a cyclic group with order 3 and a cyclic group with order 4; （2） if G＇ is nilpotent, then G is a group of {2,3,5 }.展开更多
The traditional teacher-centered ESL class has been prevalent in China for years. Under this circumstance, teachers tend to adopt a spoon-fed teaching method, and become the dominator in ESL class by setting the same ...The traditional teacher-centered ESL class has been prevalent in China for years. Under this circumstance, teachers tend to adopt a spoon-fed teaching method, and become the dominator in ESL class by setting the same instructional pace, explaining a grammar point, leading drill work; while the students' in-class participation is relatively low. As a result, students with different learning styles often feel suffocated in this teacher-dominated class; they desire to have more opportunities to participate in the free interactions or group discussions.Based on the theoretical framework of interactive teaching approach suggested by Lightbown and Spada(1993),the research aims to analyze the merits of students' in-group interaction and to examine the feasibility of implementing it in Chinese ESL class. The research reveals that in-group interaction can cultivate students' independent learning habits by granting them autonomy to bring about the problem and tackle them. Nonetheless, different perceptions from several students and teachers upon group work may influence the usefulness. The research strives to be instructive for the more efficient application of in-group interaction in Chinese ESL class.展开更多
The main purpose of this paper is to solve the class equation in an alternating group, (i.e. find the solutions set ) and find the number of these solutions where ranges over the conjugacy class in and d is a positive...The main purpose of this paper is to solve the class equation in an alternating group, (i.e. find the solutions set ) and find the number of these solutions where ranges over the conjugacy class in and d is a positive integer. In this paper we solve the class equation in where , for all . is the complement set of where { of , with all parts of are different and odd}. is conjugacy class of and form class depends on the cycle type of its elements If and , then splits into the two classes of .展开更多
The determination of the elements of groups ⅢA and ⅣA by means of microwave plasma torch atomic emission spectrometry(MPT AES) was studied systematically. Sample solutions were introduced into the plasma with a pn...The determination of the elements of groups ⅢA and ⅣA by means of microwave plasma torch atomic emission spectrometry(MPT AES) was studied systematically. Sample solutions were introduced into the plasma with a pneumatic nebulizer in continuous sampling mode and flow injection (FI) mode. The emission characteristics of these elements were investigated in details, and the basic data obtained are very important to the development of MPT AES. The analytical performances were examined. For most elements, the detection limits obtained by this method were principally the same as those obtained by inductively coupled plasma atomic emission spectrometry (ICP AES).展开更多
A novel method for analysing the performance of power saving class of Type Ⅲ in IEEE 802.16e is proposed,which is applicable to design,maintenance and management for mobile wireless metropolitan area network.Consider...A novel method for analysing the performance of power saving class of Type Ⅲ in IEEE 802.16e is proposed,which is applicable to design,maintenance and management for mobile wireless metropolitan area network.Considering the memoryless nature of user initiated packet arrival,a Geom/G/1 queue model with multiple vacations and setup period is built to capture the principle for the power saving class of Type Ⅲ.By using an embedded Markov chain method and the boundary state variable theory,we obtain the queueing measures such as queueing length,waiting time and busy cycle in steady state.Correspondingly,we derive explicitly the performance measures for the power saving class of Type Ⅲ in terms of handover ratio,energy saving ratio,and average packet response time.Based on numerical results,we develop a cost function to determine numerically the optimal length of sleep window and the minimal cost with different offered loads.展开更多
基金Supported by Fujian Province Natural Science Foundation,Nos.2016J01437,2017J01260 and 2018J01266the Fujian Medical Innovation Project,No.2015-CX-8+1 种基金the Peking University Cancer Hospital and Institute,Key Laboratory of Carcinogenesis and Translational Research,Ministry of Education/Beijing(2017 Open Project-9)Joint Funds for the innovation of science and Technology,Fujian Province,No.2017Y9074
文摘AIM To assess the long-term prognostic value of vascular endothelial growth factor receptor 1(VEGFR1)and classⅢβ-tubulin(TUBB3)mRNA expression in nonmetastatic rectal cancer.METHODS A total of 75 consecutive patients with non-metastatic rectal cancer from March 2004 to November 2008 were analyzed retrospectively at our institute.The mRNA expressions of VEGFR1 and TUBB3 were detected by multiplex branched DNA liquid-chip technology.The Cutoff Finder application was applied to determine cutoff point of mRNA expression.SPSS software version 22.0was used for analysis.RESULTS The median follow-up was 102.7 mo(range,6-153.6).Theχ~2 and Fisher’s exact tests showed that VEGFR1expression was related to lymph node metastasis(P=0.013),while no relationships between TUBB3 and clinicopathological features were observed.Univariate analysis showed that T stage,lymph node metastasis,tumor differentiation,VEGFR1 and TUBB3 mRNA expression were correlated to overall survival(OS)(P=0.048,P=0.003,P=0.052,P=0.003 and P=0.015,respectively).Also,lymph node metastasis and VEGFR1expression independently influenced OS by multivariate analysis(P=0.027 and P=0.033).VEGFR1 expression was positively correlated with TUBB3(P=0.024).The patients with low expression of both TUBB3 and VEGFR1 presented a better OS(P=0.003).In addition,the receiver operating characteristic analysis suggested that the combination of lymph node metastasis and VEGFR1 had a more favorable prognostic value(P<0.001).CONCLUSION VEGFR1 expression and lymph node metastasis independently and jointly affect survival.Moreover,low expression of VEGFR1 and TUBB3 presented a better OS in patients with non-metastatic rectal cancer,which might serve as a potential prognostic factor.
基金supported by the NSFC(11072125 and 11272175)the NSF of Jiangsu Province(SBK201140044)the Specialized Research Fund for Doctoral Program of Higher Education(20130002110044)
文摘This paper further extends the generalized covari ant derivative from the first covariant derivative to the sec ond one on curved surfaces. Through the linear transforma tion between the first generalized covariant derivative and the second one, the second covariant differential transformation group is set up. Under this transformation group, the sec ond class of differential invariants and integral invariants on curved surfaces is made clear. Besides, the symmetric struc ture of the tensor analysis on curved surfaces are revealed.
文摘In this paper we study the convergence nf a class of means on H^p(G)(0<p<1),the means take the Bochner-Riesz means in[1],the generalized Bochner-Riesz means in[2],and the operators T^(Φ_r)in[3]as special cases.We obtain weak-type estimates for the associated maximal operators and the maximal mean boundedness for the means.
基金The NSF (10771132) of Chinathe Science and Technology Foundation (20081022) of Shanxi Province for Collegesthe Team Innovation Research Foundation of Shanxi University of Finance and Economics
文摘A finite group G is called a Camina group if G has a proper normal subgroup N such that gN is precisely a conjugacy class of G for any g ∈E G - N. In this paper, the structure of a Camina group G is determined when N is a union of 2, 3 or 4 conjugacy classes of G.
文摘Quadratic-field cryptosystem is a cryptosystem built from discrete logarithm problem in ideal class groups of quadratic fields(CL-DLP). The problem on digital signature scheme based on ideal class groups of quadratic fields remained open, because of the difficulty of computing class numbers of quadratic fields. In this paper, according to our researches on quadratic fields, we construct the first digital signature scheme in ideal class groups of quadratic fields, using q as modulus, which denotes the prime divisors of ideal class numbers of quadratic fields. Security of the new signature scheme is based fully on CL-DLP. This paper also investigates realization of the scheme, and proposes the concrete technique. In addition, the technique introduced in the paper can be utilized to realize signature schemes of other kinds.
基金The Natural Science Foundation ofChongqing Education Committee (No.KG051107)
文摘Let G be a finite group with the property that for any conjugacy class order, G has exactly two conjugacy classes which have the same order. We prove that： （1） ff a Sylow 2-subgroup of G is Abelian, then G is isomorphic to the direct product of symmetric group with order 3 and cyclic group with order 2, or G is isomorphic to the semidirect product of a cyclic group with order 3 and a cyclic group with order 4; （2） if G＇ is nilpotent, then G is a group of {2,3,5 }.
文摘The traditional teacher-centered ESL class has been prevalent in China for years. Under this circumstance, teachers tend to adopt a spoon-fed teaching method, and become the dominator in ESL class by setting the same instructional pace, explaining a grammar point, leading drill work; while the students' in-class participation is relatively low. As a result, students with different learning styles often feel suffocated in this teacher-dominated class; they desire to have more opportunities to participate in the free interactions or group discussions.Based on the theoretical framework of interactive teaching approach suggested by Lightbown and Spada(1993),the research aims to analyze the merits of students' in-group interaction and to examine the feasibility of implementing it in Chinese ESL class. The research reveals that in-group interaction can cultivate students' independent learning habits by granting them autonomy to bring about the problem and tackle them. Nonetheless, different perceptions from several students and teachers upon group work may influence the usefulness. The research strives to be instructive for the more efficient application of in-group interaction in Chinese ESL class.
文摘The main purpose of this paper is to solve the class equation in an alternating group, (i.e. find the solutions set ) and find the number of these solutions where ranges over the conjugacy class in and d is a positive integer. In this paper we solve the class equation in where , for all . is the complement set of where { of , with all parts of are different and odd}. is conjugacy class of and form class depends on the cycle type of its elements If and , then splits into the two classes of .
文摘The determination of the elements of groups ⅢA and ⅣA by means of microwave plasma torch atomic emission spectrometry(MPT AES) was studied systematically. Sample solutions were introduced into the plasma with a pneumatic nebulizer in continuous sampling mode and flow injection (FI) mode. The emission characteristics of these elements were investigated in details, and the basic data obtained are very important to the development of MPT AES. The analytical performances were examined. For most elements, the detection limits obtained by this method were principally the same as those obtained by inductively coupled plasma atomic emission spectrometry (ICP AES).
基金Supported by the National Natural Science Foundation of China (No.10671170,60773100)the Natural Science Foundation of Hebei Province,China (No.2009000475)
文摘A novel method for analysing the performance of power saving class of Type Ⅲ in IEEE 802.16e is proposed,which is applicable to design,maintenance and management for mobile wireless metropolitan area network.Considering the memoryless nature of user initiated packet arrival,a Geom/G/1 queue model with multiple vacations and setup period is built to capture the principle for the power saving class of Type Ⅲ.By using an embedded Markov chain method and the boundary state variable theory,we obtain the queueing measures such as queueing length,waiting time and busy cycle in steady state.Correspondingly,we derive explicitly the performance measures for the power saving class of Type Ⅲ in terms of handover ratio,energy saving ratio,and average packet response time.Based on numerical results,we develop a cost function to determine numerically the optimal length of sleep window and the minimal cost with different offered loads.
