Objective: To study the effect and side-effects of Duodongning (DDN), a traditional Chinese medicine (TCM) granule in treating attention-deficit/hyperactivity disorder (ADHD). Methods: Double blind method was used to ...Objective: To study the effect and side-effects of Duodongning (DDN), a traditional Chinese medicine (TCM) granule in treating attention-deficit/hyperactivity disorder (ADHD). Methods: Double blind method was used to compare DDN with ritalin for ADHD in clinical practice from December 1995 to December 1996. The total number of cases was 70. Results: There were 37 cases in DDN group, with 17 cases (45.9%) markedly effective, 16 cases (43.2%) effective, the Conners hyperactive index (HI) 2.01±0.83 (before treatment), 1.17±0.76 (after 4 weeks' treatment); and there were 33 cases in the ritalin group, with 15 cases (45.5%) markedly effective, 14 cases (42.4%) effective, HI 2.07±0.91 (before treatment), 1.47±0.79 (after 4 weeks' treatment). Insignificant difference existed between the effectiveness in these 2 groups (P>0.05). The chief side-effects were 3 cases (8.1%) of anorexia in DDN group, and 7 cases (21.2%) in ritalin group. Conclusion: The effect of DDN is not significantly different from that of ritalin, and the side-effects in ritalin group were more than those in DDN group.展开更多
文摘Objective: To study the effect and side-effects of Duodongning (DDN), a traditional Chinese medicine (TCM) granule in treating attention-deficit/hyperactivity disorder (ADHD). Methods: Double blind method was used to compare DDN with ritalin for ADHD in clinical practice from December 1995 to December 1996. The total number of cases was 70. Results: There were 37 cases in DDN group, with 17 cases (45.9%) markedly effective, 16 cases (43.2%) effective, the Conners hyperactive index (HI) 2.01±0.83 (before treatment), 1.17±0.76 (after 4 weeks' treatment); and there were 33 cases in the ritalin group, with 15 cases (45.5%) markedly effective, 14 cases (42.4%) effective, HI 2.07±0.91 (before treatment), 1.47±0.79 (after 4 weeks' treatment). Insignificant difference existed between the effectiveness in these 2 groups (P>0.05). The chief side-effects were 3 cases (8.1%) of anorexia in DDN group, and 7 cases (21.2%) in ritalin group. Conclusion: The effect of DDN is not significantly different from that of ritalin, and the side-effects in ritalin group were more than those in DDN group.
