Objective To probe into whether an acupoint-like and meridian-like structure was existed in platyfish. Methods Adult platyfish was put in 30 μM 4-Di-2-ASP water solution for 3 h, then, in pipe water for 20min, afterw...Objective To probe into whether an acupoint-like and meridian-like structure was existed in platyfish. Methods Adult platyfish was put in 30 μM 4-Di-2-ASP water solution for 3 h, then, in pipe water for 20min, afterward, the fish was anesthetized in 10% aether water solution, and the fluorescent labeling was observed under fluorescent microscope with B-3A combination filter. Results The labels observed under the microscope were in round bright dot, a majority of dots were distributed separately and a part of them was in cluster (2- 5 dots/cluster) on various parts of the body in regular arrangement. The labels on the head were circularly distributed around the eye and two arches were formed posterior to the eye and in the inferior 3/4 quadrant. These two arches joined one arch in the anterior superior 1/4 quadrant. On the fish trunk, it was observed that the labels were distributed from the back to the abdomen along the longitudinal axis of the trunk, forming 6 lines, located on No. 2, 4, 6, 7, 8 and 9 scale rows successively on the dorsal part of fish. Each line was composed of 7 to 22 label clusters and 1 -5 labels were counted in each cluster. The labels were arranged as 3-4 lines on the tail. Conclusion 1) Acupoint-like and meridian-like structure was existed in platyfish. 2)The skin sensory organs of animal were not distributed evenly all over the body. Instead, a number of sensory organs were put together in cluster and a number of them were in linear distribution regularly along the long axis of the trunk, which was similar to the distribution of traditional meridians and acupoints.展开更多
Teacher Talk (TT) is an important language input in EFL (English as a Foreign Language) class and the quality of TT is closely related with the proficiency of second language acquisition. In recent years, many sch...Teacher Talk (TT) is an important language input in EFL (English as a Foreign Language) class and the quality of TT is closely related with the proficiency of second language acquisition. In recent years, many scholars have carried out some theoretical and empirical studies on the various features of TT. Based on the papers published in some world key journals, this paper has made a comparison between Chinese scholars and western scholars on the research features of TT in terms of the three levels: research subject, research methodology and research content. The paper has also proposed some suggestions on how to improve Chinese English teacher's talk and the classroom teaching quality.展开更多
To understand the high yield and efficiency technique in hybrid rice Zhongzheyou No. 1, we conducted the correlation analysis, regression analysis and path analysis of hybrid rice Zhongzheyou No. 1 based on the data o...To understand the high yield and efficiency technique in hybrid rice Zhongzheyou No. 1, we conducted the correlation analysis, regression analysis and path analysis of hybrid rice Zhongzheyou No. 1 based on the data of its ear, grain and weight at different yield levels. From this study, we put forward the high yield and efficiency technique in Zhongzheyou No. 1 .. on the basis of certain effective ear number, filled grains per ear should be mainly targeted with a consideration to 1 000-grain weight.展开更多
The process of translation is an important part of cross-cultural studies. Cross-cultural researchers are often confronted by the need to translate instruments from one language to another. In the translation, linguis...The process of translation is an important part of cross-cultural studies. Cross-cultural researchers are often confronted by the need to translate instruments from one language to another. In the translation, linguistic equivalence, functional equivalence, cultural equivalence and metric equivalence are factors that need to be considered greatly. This paper examines the translation of cross-cultural research instrument from these points of view, illustrates with examples and puts forward suggestions for incorporating each factor into research studies.展开更多
The effects of an exogenous probiotic( Bacillus amyloliquefaciens) on microbial community structure of B ranchionus plicatils and A rtemia sinica were evaluated in this study during turbot( Scophthalmus maximus) larva...The effects of an exogenous probiotic( Bacillus amyloliquefaciens) on microbial community structure of B ranchionus plicatils and A rtemia sinica were evaluated in this study during turbot( Scophthalmus maximus) larval breeding. The analysis and comparison of the microfloral composition of live feed with probiotic was conducted using the Illumina HiSeq PE250. The abundance of microbial species and diversity of microflora in live feed with B. amyloliquefaciens were higher than those in the control. The microfloral composition was similar among the three replicate experimental groups of B. plicatils compared with the control after enrichment. L actococcus, Pseudoalteromonas, and Alteromonas were always dominant. Additionally, some other bacterial species became dominant during the enrichment process. The microbial community during nutrient enrichment of A. sinica was rather similar among the three control replicates. Relative abundance of Cobetia sp., the most dominant species, was 54%–65.2%. Similarity in the microbial community was still high after adding B. amyloliquefaciens. Furthermore, P seudoalteromonas and Alteromonas replaced Cobetia as the dominant species, and the abundance of Cobetia decreased to 4.3%–25.3%. Mean common ratios at the operational taxonomic unit level were 50%–60% between the two B. plicatils and A. sinica treatments. Therefore, the microbial community structure changed after adding B. amyloliquefaciens during nutrient enrichment of B. plicatils or A. sinica and tended to stabilize. Additionally, the abundance of V ibrio in any kind of live feed was not significantly dif ferent from that in the control. These results will help improve the microflora of B. plicatils and A. sinica and can be used to understand the multiple-level transfer role of probiotic species among probiotic products, microflora of live feed, and fish larvae.展开更多
There are four steps in the interaction between intestinal microbes and mucosal inflammation in genetically predisposed individuals from the viewpoints of basic and clinical aspects of inflammatory bowel disease (IBD...There are four steps in the interaction between intestinal microbes and mucosal inflammation in genetically predisposed individuals from the viewpoints of basic and clinical aspects of inflammatory bowel disease (IBD). The first step is an interaction between intestinal microbes or their components and intestinal epithelial cells via receptors, the second step an interaction between macrophages and dendritic cells and mucosal lymphocytes, the third step an interaction between lymphocytes and vascular endothelial cells, and the fourth step an interaction between lymphocytes and granulocytes producing proinflammatory cytokines or free radicals and mucosal damage and repair. Recent therapeutic approaches for IBD aim to block these four steps in the intestinal inflammation of patients with IBD.展开更多
The experiments of one-stage semi-circular and two-stage semi-circular impinging stream drying as well as the vertical and semi-circular combined impinging stream drying were carried out. The velocity distribution and...The experiments of one-stage semi-circular and two-stage semi-circular impinging stream drying as well as the vertical and semi-circular combined impinging stream drying were carried out. The velocity distribution and the mean residence time of particles, and the influence of various factors on drying characteristics were studied. A mathematical model of granular material drying in a semi-circular impinging stream dryer was proposed, in which the flow characteristics as well as the heat and mass transfer mechanisms were considered. Reasonable numerical methods were used to solve the equations. Under various conditions, the calculated results agree well with the experimental data. The unsteady-state drying dynamic equation, as well as the variations of drying rate and moisture content versus time were obtained. The results indicate that constant drying rate period does not exist in a semi-circular impinging stream dryer. Appropriate semi-circular stage number and curvature radius, flow-rate ratio, air velocity, and higher inlet air temperature should be used for enhancing the drying process.展开更多
Many researchers in China are actively engaged in the development of new types of wrought magnesium alloys with low cost or with high-performances and novel plastic processing technologies.The research activities are ...Many researchers in China are actively engaged in the development of new types of wrought magnesium alloys with low cost or with high-performances and novel plastic processing technologies.The research activities are funded primarily through four government-supported programs:the Key Technologies R&D Program of China,the National Basic Research Program of China,the National High-tech R&D Program of China,and the National Natural Science Foundation of China.The key R&D activities for the development of new wrought magnesium alloys in China are reviewed,and typical properties of some new alloys are summarized. More attentions are paid to high-strength wrought magnesium alloys and high-plasticity wrought magnesium alloys.Some novel plastic processing technologies,emerging in recent years,which aim to control deformation texture and to improve plasticity and formability especially at room temperature,are also introduced.展开更多
Participatory and integrated research approaches employed by a long-term Thai- Vietnamese-German collaborative research program, ‘The Uplands Program’, that address the vicious circles of resource scarcity, environm...Participatory and integrated research approaches employed by a long-term Thai- Vietnamese-German collaborative research program, ‘The Uplands Program’, that address the vicious circles of resource scarcity, environmental degrada- tion and rural poverty in mountainous regions of northern Thailand and northern Vietnam are discussed in this paper. We present two examples from the Thai component of the research program to show how different disciplines and stakeholders need to cooperate at different scales to make meaningful scientific contributions towards sustainable land use and rural development in mountainous regions. The case of resource conservation in the Thai highlands shows that local and scientific knowledge, conven- tional surveys and participatory modeling can be creatively combined. Integrated research on the potential of integrating fruit trees and associated technologies into mountain farming systems suggests that natural scientists have to work alongsideeconomists and social scientists to avoid harmful effects of purely technology-driven and productivity- enhancing approaches. The success of new technologies cannot be measured solely by adoption rates and yield increases, but also needs to take into account their long-term impact on various groups of farmers and the ecological, economic and social trade-offs that they entail. Technical and institutional innovations need to go hand in hand to provide viable livelihood opportunities for smallholder farmers in mountain watersheds. The major lesson learned from the first six years of our research in the mountains of Thailand and Vietnam is that conventional and participatory approaches are not antagonistic; if scientists from various disciplines and research paradigms are open-minded, the combination of both approaches can produce meaningful results that cater for the needs of both the academic community and local stakeholders in mountain environments.展开更多
Locating the marine target in a quick and precise way is the crucial point of implementing SAR (search and rescue) at sea, which involves aspects of developing SAR strategy and detects the marine targets. As the eff...Locating the marine target in a quick and precise way is the crucial point of implementing SAR (search and rescue) at sea, which involves aspects of developing SAR strategy and detects the marine targets. As the effect of marine target detection restricts the SAR result directly, the study has focused on reviewing the previous research about marine target detection, especially dim marine target detection. What's more, small target detection under complex sea status is one of the severe challenges which is research's hotspot and needs more endeavor. Current research results and future research directions are discussed in the paper. The findings can provide systematic view of implementing maritime search and rescue for field researchers and governors.展开更多
Research in applied linguistics, like research in other fields, is usually carried out by two approaches: quantitative approach and qualitative approach. It is agreed "both approach are needed, since no one methodol...Research in applied linguistics, like research in other fields, is usually carried out by two approaches: quantitative approach and qualitative approach. It is agreed "both approach are needed, since no one methodology can answer all questions and provide insights on all issues". The two approaches follow different procedures and inevitably have respective advantages and drawbacks. Three general types of quantitative methods are experiments, quasi-experiments and surveys. Three general types of methods concerning qualitative approach used in linguistics are case study, action research and ethnographic research. Different types of research questions can be studied through various research methods. It is important to recognise the distinction between quantitative approach and qualitative approaches. It is up to the researcher to choose the specific approach in accordance with the suitability of the method for the particular research. It can be a single approach, or combination of the two, providing it allows maximal reliability and validity of the study.展开更多
News release to the latest science f indings is benef icial to both researchers and their served institutions as well as the public. It will help to set a bridge of communication between researchers, the public and me...News release to the latest science f indings is benef icial to both researchers and their served institutions as well as the public. It will help to set a bridge of communication between researchers, the public and media, and publishers, making the latest research findings well known to the public. World Journal of Gastroenterology has currently freely opened the News Release Service System (WJG-NRSS) for original articles with potential signifi cance and novelty for news release to mass media to broaden the f indings to the public.展开更多
Meta-analysis is a kind of systematic review,which uses quantitative method to summarize the results.It is a comprehensive evaluation to the findings of previous studies with higher credibility.Recently,it is applied ...Meta-analysis is a kind of systematic review,which uses quantitative method to summarize the results.It is a comprehensive evaluation to the findings of previous studies with higher credibility.Recently,it is applied to all areas of scientific research,particularly in the integrated treatment of breast cancer.Currently,breast cancer is known one of the most common malignant tumors,and its incidence is increasing year by year.Therefore,more and more clinical doctors pay attention to the effect of comprehensive treatment for patients with breast cancer.This article mainly collects the results of comprehensive treatment of breast cancer,in which the method of Meta-analysis is applied.In addition,we discuss the latest progress in order to guide the clinical treatment.展开更多
The literature illustrates the important issue of physician adherence to guidelines in their daily practice. In a quantitative study, we asked a random sample of 100 hospital gastroenterologists to evaluate their know...The literature illustrates the important issue of physician adherence to guidelines in their daily practice. In a quantitative study, we asked a random sample of 100 hospital gastroenterologists to evaluate their knowledge of guidelines and awareness of promoters. The degree to which guidelines were considered reliable was not related to the scientific evidence but was significantly associated with the promoter. The French Society of Gastroenterology was considered to be a more reliable promoter than national health agencies and pharmaceutical industries. Gastroenterologists become aware of guidelines mainly through their specialty society (62%). Specialty societies appear to be a more important source of information on guidelines for physicians. National health agencies should involve the specialty societies in the guideline development process to achieve changes in clinical practice.展开更多
Most research in support of agricultural development and natural resource management in densely settled mountain ecosystems continues to emphasize component over system-level goals. Research by plant breeders, foreste...Most research in support of agricultural development and natural resource management in densely settled mountain ecosystems continues to emphasize component over system-level goals. Research by plant breeders, foresters and animal scientists is generally designed to maximize the yield of products within their particular area of expertise (edible plant parts, tree products and livestock products, respectively), while soil scientists aim largely to increase soil nutrient stocks. At landscape level the same dynamic holds within the agronomic sciences, while water engineers work independently to conserve water through its isolation from broader landscape dynamics, and other common property resources remain largely ignored. Opportunities to foster positive synergies between system components, and to integrate livelihood with conservation goals, are generally missed. This paper presents experiences of the African Highlands Initiative, an ecoregional program of the Consultative Group for International Agricultural Research (CGIAR) and a network of the Association for Strengthening Agricultural Research in Eastern and Central Africa (ASARECA), in operationalizing integrated research at farm and landscape scale. Following a discussion of the shortcomings of the conventional research paradigm that beg for strongerintegration and a review of the contributions of extant research paradigms that help us move in the right direction, the paper lays a conceptual foundation for integrated research. System components at farm and landscape level are delineated, and this somewhat arbitrary conceptual partitioning of agroecological systems shown to influence the current research paradigm as well as the partitioning of institutional mandates. Diverse meanings of systems integration are then discussed to illustrate the synergies that might be built into agricultural and natural resource research programs. The distinction between the logic of maximization and optimization is then utilized to distinguish between component and “system-level” goals. This conceptual overview is followed by several case studies to illustrate how these concepts can guide the formulation of integrated research objectives, methods and outputs at farm and landscape scale. The paper concludes with a discussion of the implications of this alternative research paradigm for the structure, function and skill base of national and international agricultural research systems.展开更多
文摘Objective To probe into whether an acupoint-like and meridian-like structure was existed in platyfish. Methods Adult platyfish was put in 30 μM 4-Di-2-ASP water solution for 3 h, then, in pipe water for 20min, afterward, the fish was anesthetized in 10% aether water solution, and the fluorescent labeling was observed under fluorescent microscope with B-3A combination filter. Results The labels observed under the microscope were in round bright dot, a majority of dots were distributed separately and a part of them was in cluster (2- 5 dots/cluster) on various parts of the body in regular arrangement. The labels on the head were circularly distributed around the eye and two arches were formed posterior to the eye and in the inferior 3/4 quadrant. These two arches joined one arch in the anterior superior 1/4 quadrant. On the fish trunk, it was observed that the labels were distributed from the back to the abdomen along the longitudinal axis of the trunk, forming 6 lines, located on No. 2, 4, 6, 7, 8 and 9 scale rows successively on the dorsal part of fish. Each line was composed of 7 to 22 label clusters and 1 -5 labels were counted in each cluster. The labels were arranged as 3-4 lines on the tail. Conclusion 1) Acupoint-like and meridian-like structure was existed in platyfish. 2)The skin sensory organs of animal were not distributed evenly all over the body. Instead, a number of sensory organs were put together in cluster and a number of them were in linear distribution regularly along the long axis of the trunk, which was similar to the distribution of traditional meridians and acupoints.
文摘Teacher Talk (TT) is an important language input in EFL (English as a Foreign Language) class and the quality of TT is closely related with the proficiency of second language acquisition. In recent years, many scholars have carried out some theoretical and empirical studies on the various features of TT. Based on the papers published in some world key journals, this paper has made a comparison between Chinese scholars and western scholars on the research features of TT in terms of the three levels: research subject, research methodology and research content. The paper has also proposed some suggestions on how to improve Chinese English teacher's talk and the classroom teaching quality.
文摘To understand the high yield and efficiency technique in hybrid rice Zhongzheyou No. 1, we conducted the correlation analysis, regression analysis and path analysis of hybrid rice Zhongzheyou No. 1 based on the data of its ear, grain and weight at different yield levels. From this study, we put forward the high yield and efficiency technique in Zhongzheyou No. 1 .. on the basis of certain effective ear number, filled grains per ear should be mainly targeted with a consideration to 1 000-grain weight.
文摘The process of translation is an important part of cross-cultural studies. Cross-cultural researchers are often confronted by the need to translate instruments from one language to another. In the translation, linguistic equivalence, functional equivalence, cultural equivalence and metric equivalence are factors that need to be considered greatly. This paper examines the translation of cross-cultural research instrument from these points of view, illustrates with examples and puts forward suggestions for incorporating each factor into research studies.
基金Supported by the National Natural Science Foundation of China(No.31302206)the Postdoctoral Applied Research Project of Qingdao(No.Q51201607)
文摘The effects of an exogenous probiotic( Bacillus amyloliquefaciens) on microbial community structure of B ranchionus plicatils and A rtemia sinica were evaluated in this study during turbot( Scophthalmus maximus) larval breeding. The analysis and comparison of the microfloral composition of live feed with probiotic was conducted using the Illumina HiSeq PE250. The abundance of microbial species and diversity of microflora in live feed with B. amyloliquefaciens were higher than those in the control. The microfloral composition was similar among the three replicate experimental groups of B. plicatils compared with the control after enrichment. L actococcus, Pseudoalteromonas, and Alteromonas were always dominant. Additionally, some other bacterial species became dominant during the enrichment process. The microbial community during nutrient enrichment of A. sinica was rather similar among the three control replicates. Relative abundance of Cobetia sp., the most dominant species, was 54%–65.2%. Similarity in the microbial community was still high after adding B. amyloliquefaciens. Furthermore, P seudoalteromonas and Alteromonas replaced Cobetia as the dominant species, and the abundance of Cobetia decreased to 4.3%–25.3%. Mean common ratios at the operational taxonomic unit level were 50%–60% between the two B. plicatils and A. sinica treatments. Therefore, the microbial community structure changed after adding B. amyloliquefaciens during nutrient enrichment of B. plicatils or A. sinica and tended to stabilize. Additionally, the abundance of V ibrio in any kind of live feed was not significantly dif ferent from that in the control. These results will help improve the microflora of B. plicatils and A. sinica and can be used to understand the multiple-level transfer role of probiotic species among probiotic products, microflora of live feed, and fish larvae.
文摘There are four steps in the interaction between intestinal microbes and mucosal inflammation in genetically predisposed individuals from the viewpoints of basic and clinical aspects of inflammatory bowel disease (IBD). The first step is an interaction between intestinal microbes or their components and intestinal epithelial cells via receptors, the second step an interaction between macrophages and dendritic cells and mucosal lymphocytes, the third step an interaction between lymphocytes and vascular endothelial cells, and the fourth step an interaction between lymphocytes and granulocytes producing proinflammatory cytokines or free radicals and mucosal damage and repair. Recent therapeutic approaches for IBD aim to block these four steps in the intestinal inflammation of patients with IBD.
基金Supported by the State Key Fundamental Research Plan of China (No. G20000263) and the Director Foundation of Institute of Engineering Thermophysics, Chinese Academy of Sciences.
文摘The experiments of one-stage semi-circular and two-stage semi-circular impinging stream drying as well as the vertical and semi-circular combined impinging stream drying were carried out. The velocity distribution and the mean residence time of particles, and the influence of various factors on drying characteristics were studied. A mathematical model of granular material drying in a semi-circular impinging stream dryer was proposed, in which the flow characteristics as well as the heat and mass transfer mechanisms were considered. Reasonable numerical methods were used to solve the equations. Under various conditions, the calculated results agree well with the experimental data. The unsteady-state drying dynamic equation, as well as the variations of drying rate and moisture content versus time were obtained. The results indicate that constant drying rate period does not exist in a semi-circular impinging stream dryer. Appropriate semi-circular stage number and curvature radius, flow-rate ratio, air velocity, and higher inlet air temperature should be used for enhancing the drying process.
基金Project(50725413)supported by the National Natural Science Foundation of ChinaProject(2007CB613704)supported by the National Basic Research Program of ChinaProject(2008DFR50040)supported by the International Cooperation Program of Ministry of Science and Technology of China
文摘Many researchers in China are actively engaged in the development of new types of wrought magnesium alloys with low cost or with high-performances and novel plastic processing technologies.The research activities are funded primarily through four government-supported programs:the Key Technologies R&D Program of China,the National Basic Research Program of China,the National High-tech R&D Program of China,and the National Natural Science Foundation of China.The key R&D activities for the development of new wrought magnesium alloys in China are reviewed,and typical properties of some new alloys are summarized. More attentions are paid to high-strength wrought magnesium alloys and high-plasticity wrought magnesium alloys.Some novel plastic processing technologies,emerging in recent years,which aim to control deformation texture and to improve plasticity and formability especially at room temperature,are also introduced.
文摘Participatory and integrated research approaches employed by a long-term Thai- Vietnamese-German collaborative research program, ‘The Uplands Program’, that address the vicious circles of resource scarcity, environmental degrada- tion and rural poverty in mountainous regions of northern Thailand and northern Vietnam are discussed in this paper. We present two examples from the Thai component of the research program to show how different disciplines and stakeholders need to cooperate at different scales to make meaningful scientific contributions towards sustainable land use and rural development in mountainous regions. The case of resource conservation in the Thai highlands shows that local and scientific knowledge, conven- tional surveys and participatory modeling can be creatively combined. Integrated research on the potential of integrating fruit trees and associated technologies into mountain farming systems suggests that natural scientists have to work alongsideeconomists and social scientists to avoid harmful effects of purely technology-driven and productivity- enhancing approaches. The success of new technologies cannot be measured solely by adoption rates and yield increases, but also needs to take into account their long-term impact on various groups of farmers and the ecological, economic and social trade-offs that they entail. Technical and institutional innovations need to go hand in hand to provide viable livelihood opportunities for smallholder farmers in mountain watersheds. The major lesson learned from the first six years of our research in the mountains of Thailand and Vietnam is that conventional and participatory approaches are not antagonistic; if scientists from various disciplines and research paradigms are open-minded, the combination of both approaches can produce meaningful results that cater for the needs of both the academic community and local stakeholders in mountain environments.
基金The authors appreciate the project support from China Scholarship Council, and the National Natural Science Foundation of China (51579143, 51379121, 61304230), Shanghai Shuguang Plan Project (No: 15SG44) and China Postdoctoral Foundation (No. 2015M581585).
文摘Locating the marine target in a quick and precise way is the crucial point of implementing SAR (search and rescue) at sea, which involves aspects of developing SAR strategy and detects the marine targets. As the effect of marine target detection restricts the SAR result directly, the study has focused on reviewing the previous research about marine target detection, especially dim marine target detection. What's more, small target detection under complex sea status is one of the severe challenges which is research's hotspot and needs more endeavor. Current research results and future research directions are discussed in the paper. The findings can provide systematic view of implementing maritime search and rescue for field researchers and governors.
文摘Research in applied linguistics, like research in other fields, is usually carried out by two approaches: quantitative approach and qualitative approach. It is agreed "both approach are needed, since no one methodology can answer all questions and provide insights on all issues". The two approaches follow different procedures and inevitably have respective advantages and drawbacks. Three general types of quantitative methods are experiments, quasi-experiments and surveys. Three general types of methods concerning qualitative approach used in linguistics are case study, action research and ethnographic research. Different types of research questions can be studied through various research methods. It is important to recognise the distinction between quantitative approach and qualitative approaches. It is up to the researcher to choose the specific approach in accordance with the suitability of the method for the particular research. It can be a single approach, or combination of the two, providing it allows maximal reliability and validity of the study.
文摘News release to the latest science f indings is benef icial to both researchers and their served institutions as well as the public. It will help to set a bridge of communication between researchers, the public and media, and publishers, making the latest research findings well known to the public. World Journal of Gastroenterology has currently freely opened the News Release Service System (WJG-NRSS) for original articles with potential signifi cance and novelty for news release to mass media to broaden the f indings to the public.
文摘Meta-analysis is a kind of systematic review,which uses quantitative method to summarize the results.It is a comprehensive evaluation to the findings of previous studies with higher credibility.Recently,it is applied to all areas of scientific research,particularly in the integrated treatment of breast cancer.Currently,breast cancer is known one of the most common malignant tumors,and its incidence is increasing year by year.Therefore,more and more clinical doctors pay attention to the effect of comprehensive treatment for patients with breast cancer.This article mainly collects the results of comprehensive treatment of breast cancer,in which the method of Meta-analysis is applied.In addition,we discuss the latest progress in order to guide the clinical treatment.
文摘The literature illustrates the important issue of physician adherence to guidelines in their daily practice. In a quantitative study, we asked a random sample of 100 hospital gastroenterologists to evaluate their knowledge of guidelines and awareness of promoters. The degree to which guidelines were considered reliable was not related to the scientific evidence but was significantly associated with the promoter. The French Society of Gastroenterology was considered to be a more reliable promoter than national health agencies and pharmaceutical industries. Gastroenterologists become aware of guidelines mainly through their specialty society (62%). Specialty societies appear to be a more important source of information on guidelines for physicians. National health agencies should involve the specialty societies in the guideline development process to achieve changes in clinical practice.
文摘Most research in support of agricultural development and natural resource management in densely settled mountain ecosystems continues to emphasize component over system-level goals. Research by plant breeders, foresters and animal scientists is generally designed to maximize the yield of products within their particular area of expertise (edible plant parts, tree products and livestock products, respectively), while soil scientists aim largely to increase soil nutrient stocks. At landscape level the same dynamic holds within the agronomic sciences, while water engineers work independently to conserve water through its isolation from broader landscape dynamics, and other common property resources remain largely ignored. Opportunities to foster positive synergies between system components, and to integrate livelihood with conservation goals, are generally missed. This paper presents experiences of the African Highlands Initiative, an ecoregional program of the Consultative Group for International Agricultural Research (CGIAR) and a network of the Association for Strengthening Agricultural Research in Eastern and Central Africa (ASARECA), in operationalizing integrated research at farm and landscape scale. Following a discussion of the shortcomings of the conventional research paradigm that beg for strongerintegration and a review of the contributions of extant research paradigms that help us move in the right direction, the paper lays a conceptual foundation for integrated research. System components at farm and landscape level are delineated, and this somewhat arbitrary conceptual partitioning of agroecological systems shown to influence the current research paradigm as well as the partitioning of institutional mandates. Diverse meanings of systems integration are then discussed to illustrate the synergies that might be built into agricultural and natural resource research programs. The distinction between the logic of maximization and optimization is then utilized to distinguish between component and “system-level” goals. This conceptual overview is followed by several case studies to illustrate how these concepts can guide the formulation of integrated research objectives, methods and outputs at farm and landscape scale. The paper concludes with a discussion of the implications of this alternative research paradigm for the structure, function and skill base of national and international agricultural research systems.