Due to industrial activities,heavy metal concentrations in aquatic systems of Mexico,are on the rise.Zooplankton,particularly rotifers,being sensitive and common components of freshwater,are widely used in ecotoxicolo...Due to industrial activities,heavy metal concentrations in aquatic systems of Mexico,are on the rise.Zooplankton,particularly rotifers,being sensitive and common components of freshwater,are widely used in ecotoxicological tests for establishing water quality criteria.Depending on the route of exposure(i.e.via medium or algal food),the toxicity of heavy metals varies.In the present study we evaluated the effect of cadmium and mercury exposed through medium and via algal food for the rotifer B.rubens.For both the heavy metals,we exposed rotifers via medium containing Chlorella at 0.5×10^(6)cells/ml or fed daily on previously exposed(1,2 and 4 h)alga to the toxicants(using 5 times the value of LC_(50)for B.rubens).For cadmium toxicity through medium,we used 3 toxicant levels(0.1,0.2 and 0.4 mg/L)and for mercury,we used 0.005,0.010 and 0.015 mg/L.Based on the LC_(50),B.rubens was 24 times more sensitive to mercury(0.035±0.002 mg/L)than cadmium.At a concentration of 0.4 mg/L,cadmium through the medium caused increased lag phase of B.rubens.When grown on Chlorella exposed for different durations to cadmium,the rotifer density decreased with the increasing duration of algal exposure to the heavy metal.When mercury was used in the medium or via algal food,the trends in the population growth of B.rubens were similar to those for cadmium.An increase in heavy metal concentration in the medium resulted in a decrease of the rate of population increase per day(r).The r varied from 0.33(in control)to 0.02 d^(-1)(in heavy metal treatment)depending on the mode of exposure though medium or via algal food.展开更多
The new designed curtain fabric,whose two faces were covered by trilobal cross-sectional filament and dull polyester filament,was designed with three-bar tricot stitch,which possessed unique style with implicit grid e...The new designed curtain fabric,whose two faces were covered by trilobal cross-sectional filament and dull polyester filament,was designed with three-bar tricot stitch,which possessed unique style with implicit grid effects.Tricot two-sided technology was adopted in this paper and the method of spectrophotometer was used to test the optical properties,including the light transmittance and reflectance of the technical face and back side of the samples in the ultraviolet,visible,and near-infrared band.The results show that the transmittance and invisible,anti-ultraviolet properties in the thin and single-layer fabric are improved.The fabric meets the qualifications in use of curtain material.展开更多
Primary choriocarcinoma of the uterine cervix (PCC) is an extremely rare disease. The conventional treatment of PCC is a combination of hysterectomy and chemotherapy. We present one rare case proved by cervical biopsy...Primary choriocarcinoma of the uterine cervix (PCC) is an extremely rare disease. The conventional treatment of PCC is a combination of hysterectomy and chemotherapy. We present one rare case proved by cervical biopsy. The patient was an 36-year-old Chinese woman with irregular vaginal bleeding for 60 days. A cervical tumoral mass was seen in the pelvic examination and biopsy revealed active hyperplasia of trophoblastic cell. Because of massive vaginal haemorrhage, the patient accepted uterine artery drug pouring and embolism emergently. This management had gained a satisfactory effect. Thus, Uterine artery drug pouring and embolism is one new and effective weapon for PCC, which can preserve the patient’s productive ability.展开更多
Objective Corticotropin-releasing hormone（CRH）plays an important role in neuroendocrine,autonomic and behavioral responses to stressors.In the present study,the effect of chronic unpredictable mild stress（CUMS）on ...Objective Corticotropin-releasing hormone（CRH）plays an important role in neuroendocrine,autonomic and behavioral responses to stressors.In the present study,the effect of chronic unpredictable mild stress（CUMS）on CRH neurons was investigated in rat brain.Methods The rats were exposed to one of the stressors each day for 21 d.Immunostaining was performed to detect the CRH-positive neurons in the paraventricular nucleus（PVN）of the hypothalamus and in amygdala.Results After the stress protocol,the animals showed a reduction in body weight gain as well as reduced sucrose preference and locomotor activity.Interestingly,the CRH neurons in both PVN and central nucleus of the amygdala（CeA）were stimulated by CUMS.The densities of CRH-containing neurons in both PVN and CeA were significantly higher than those in control group.Conclusion The CRH systems in PVN and CeA may both contribute to depression-like behaviors during CUMS.展开更多
We consider the approximate acoustic cloaking in an inhomogeneous isotropic background space.By employing transformation media,together with the use of a sound-soft layer lining right outside the cloaked region,we sho...We consider the approximate acoustic cloaking in an inhomogeneous isotropic background space.By employing transformation media,together with the use of a sound-soft layer lining right outside the cloaked region,we show that one can achieve the near-invisibility by the"blow-up-a-small-region"construction.This is based on novel scattering estimates corresponding to multiple multi-scale obstacles located in an isotropic space.We develop a novel system of integral equations to decouple the nonlinear scattering interaction among the small obstacle components,the regular obstacle components and the inhomogeneous background medium.展开更多
When there is uncertainty in sibling relationship,the classical affected sib-pair(ASP) linkage tests may be severely biased.This can happen,for example,if some of the half sib-pairs are mixed with full sib-pairs.The g...When there is uncertainty in sibling relationship,the classical affected sib-pair(ASP) linkage tests may be severely biased.This can happen,for example,if some of the half sib-pairs are mixed with full sib-pairs.The genomic control method has been used in association analysis to adjust for population structures.We show that the same idea can be applied to ASP linkage analysis with uncertainty in sibling relationship.Assuming that,in addition to the candidate marker,null markers that are unlinked to the disease locus are also genotyped,we may use the information on these loci to estimate the proportion of half sib-pairs and to correct for the bias and variance distortion caused by the heterogeneity of sibling relationship.Unlike in association studies,the null loci are not required to be matched with the candidate marker in allele frequency for ASP linkage analysis.This makes our approach flexible in selecting null markers.In our simulations,using a number of 30 or more null loci can effectively remove the bias and variance distortion.It is also shown that,even the null loci are weakly linked to the disease locus,the proposed method can also provide satisfactory correction.展开更多
基金This research was funded by a grant from PAPIIT—IN204101.SSSS and SN also thank National System of Investigators(SNI一18723&20520)
文摘Due to industrial activities,heavy metal concentrations in aquatic systems of Mexico,are on the rise.Zooplankton,particularly rotifers,being sensitive and common components of freshwater,are widely used in ecotoxicological tests for establishing water quality criteria.Depending on the route of exposure(i.e.via medium or algal food),the toxicity of heavy metals varies.In the present study we evaluated the effect of cadmium and mercury exposed through medium and via algal food for the rotifer B.rubens.For both the heavy metals,we exposed rotifers via medium containing Chlorella at 0.5×10^(6)cells/ml or fed daily on previously exposed(1,2 and 4 h)alga to the toxicants(using 5 times the value of LC_(50)for B.rubens).For cadmium toxicity through medium,we used 3 toxicant levels(0.1,0.2 and 0.4 mg/L)and for mercury,we used 0.005,0.010 and 0.015 mg/L.Based on the LC_(50),B.rubens was 24 times more sensitive to mercury(0.035±0.002 mg/L)than cadmium.At a concentration of 0.4 mg/L,cadmium through the medium caused increased lag phase of B.rubens.When grown on Chlorella exposed for different durations to cadmium,the rotifer density decreased with the increasing duration of algal exposure to the heavy metal.When mercury was used in the medium or via algal food,the trends in the population growth of B.rubens were similar to those for cadmium.An increase in heavy metal concentration in the medium resulted in a decrease of the rate of population increase per day(r).The r varied from 0.33(in control)to 0.02 d^(-1)(in heavy metal treatment)depending on the mode of exposure though medium or via algal food.
基金Science and Technology Project of Zhejiang Province of China(No.2006C31018)
文摘The new designed curtain fabric,whose two faces were covered by trilobal cross-sectional filament and dull polyester filament,was designed with three-bar tricot stitch,which possessed unique style with implicit grid effects.Tricot two-sided technology was adopted in this paper and the method of spectrophotometer was used to test the optical properties,including the light transmittance and reflectance of the technical face and back side of the samples in the ultraviolet,visible,and near-infrared band.The results show that the transmittance and invisible,anti-ultraviolet properties in the thin and single-layer fabric are improved.The fabric meets the qualifications in use of curtain material.
文摘Primary choriocarcinoma of the uterine cervix (PCC) is an extremely rare disease. The conventional treatment of PCC is a combination of hysterectomy and chemotherapy. We present one rare case proved by cervical biopsy. The patient was an 36-year-old Chinese woman with irregular vaginal bleeding for 60 days. A cervical tumoral mass was seen in the pelvic examination and biopsy revealed active hyperplasia of trophoblastic cell. Because of massive vaginal haemorrhage, the patient accepted uterine artery drug pouring and embolism emergently. This management had gained a satisfactory effect. Thus, Uterine artery drug pouring and embolism is one new and effective weapon for PCC, which can preserve the patient’s productive ability.
文摘Objective Corticotropin-releasing hormone（CRH）plays an important role in neuroendocrine,autonomic and behavioral responses to stressors.In the present study,the effect of chronic unpredictable mild stress（CUMS）on CRH neurons was investigated in rat brain.Methods The rats were exposed to one of the stressors each day for 21 d.Immunostaining was performed to detect the CRH-positive neurons in the paraventricular nucleus（PVN）of the hypothalamus and in amygdala.Results After the stress protocol,the animals showed a reduction in body weight gain as well as reduced sucrose preference and locomotor activity.Interestingly,the CRH neurons in both PVN and central nucleus of the amygdala（CeA）were stimulated by CUMS.The densities of CRH-containing neurons in both PVN and CeA were significantly higher than those in control group.Conclusion The CRH systems in PVN and CeA may both contribute to depression-like behaviors during CUMS.
基金supported by National Natural Science Foundation of China(Grant Nos.1110141411201453+1 种基金91130022 and 91130026)National Science Foundation of USA(Grant No.DMS 1207784)
文摘We consider the approximate acoustic cloaking in an inhomogeneous isotropic background space.By employing transformation media,together with the use of a sound-soft layer lining right outside the cloaked region,we show that one can achieve the near-invisibility by the"blow-up-a-small-region"construction.This is based on novel scattering estimates corresponding to multiple multi-scale obstacles located in an isotropic space.We develop a novel system of integral equations to decouple the nonlinear scattering interaction among the small obstacle components,the regular obstacle components and the inhomogeneous background medium.
基金supported by National Natural Science Foundation of China(Grant No. 10971210)China Postdoctoral Science Foundation (Grant No. 20110490824)
文摘When there is uncertainty in sibling relationship,the classical affected sib-pair(ASP) linkage tests may be severely biased.This can happen,for example,if some of the half sib-pairs are mixed with full sib-pairs.The genomic control method has been used in association analysis to adjust for population structures.We show that the same idea can be applied to ASP linkage analysis with uncertainty in sibling relationship.Assuming that,in addition to the candidate marker,null markers that are unlinked to the disease locus are also genotyped,we may use the information on these loci to estimate the proportion of half sib-pairs and to correct for the bias and variance distortion caused by the heterogeneity of sibling relationship.Unlike in association studies,the null loci are not required to be matched with the candidate marker in allele frequency for ASP linkage analysis.This makes our approach flexible in selecting null markers.In our simulations,using a number of 30 or more null loci can effectively remove the bias and variance distortion.It is also shown that,even the null loci are weakly linked to the disease locus,the proposed method can also provide satisfactory correction.
