In recent years, Wuzhen, a Ming-Qing style water town located south of the Yangtze River, has quickly become one of the most popular tourist destinations in China. The success of Wuzhen was so influential that the te...In recent years, Wuzhen, a Ming-Qing style water town located south of the Yangtze River, has quickly become one of the most popular tourist destinations in China. The success of Wuzhen was so influential that the term ＂Wuzhen Model＂ quickly became a buzzword in Chinese economic and cultural discourses. Promoters of Wuzhen have claimed that it embodies both tradition and modernity, therefore representing the best of China. While Wuzhen was first reconstructed as a ＂living museum＂ of Chinese cultural tradition to attract tourists, it increasingly started to claim itself as a leading ＂smart town＂ for China＇s future development. Moreover, the so-called Wuzhen Model fits seamlessly into China＇s overall strategy of projecting its soft power both domestically and abroad. The purpose of this paper is to examine how Wuzhen was culturally constructed and how it helped to project China＇s soft power. It also examines how Wuzhen was perceived abroad, focusing primarily on major English-speaking countries including the United States, the United Kingdom, and Australia, to understand its impact on China＇s soft power,展开更多
Objective: To explore the analgesic and anti-inflammatory effects of lappaconitine gelata (LA). Methods: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate method in ...Objective: To explore the analgesic and anti-inflammatory effects of lappaconitine gelata (LA). Methods: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate method in the mouse, and the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were used for investigation on the analgesic and anti-inflammatory effects of LA. Results: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate methods was significantly inhibited by LA. In addition, the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were all significantly suppressed by LA. Conclusion: LA has the analgesic and anti-inflammatory effects.展开更多
In the present study,we aimed to investigate the chemical constituents and analgesic activity of Aconitum kusnezoffii Reichb. The isolation and purification of components were achieved by a series of chromatography, i...In the present study,we aimed to investigate the chemical constituents and analgesic activity of Aconitum kusnezoffii Reichb. The isolation and purification of components were achieved by a series of chromatography, including silica gel, Sephadex LH-20 and HPLC. By using spectroscopic analysis, their structures were identified. Using PDE-4A as analgesic target, moleculardocking was conducted between isolated compounds by using Schrodinger software. Neoline is a typical non-ester diterpene alkaloid. It was studied by using the mouse torsion body method and hot plate method. A total of 12 diterpene alkaloids were obtainedand identified as Mesaconitine(1), Bewutine (2), Bewudine (3), Songoramine (4), Songorine (5), Neoline (6), Talasamine (7), isotalatizidine (8), Hokbusine A (9), Mesaconine (10), 8-OEt-14-benzoylmesaconine (11), 8-Methoxy-14-benzoyl-beiwutinine (12).Compounds 9 and 12 were isolated from Aconitum kusnezoffii Reichb. for the first time. Twelve diterpenealkaloids could act on the analgesic target. Neoline is a typical non-ester diterpene alkaloid. It had significant analgesic effect. Diterpene alkaloids were the main components of Aconitum kusnezoffiiReichb., and they had good analgesic activity.展开更多
文摘In recent years, Wuzhen, a Ming-Qing style water town located south of the Yangtze River, has quickly become one of the most popular tourist destinations in China. The success of Wuzhen was so influential that the term ＂Wuzhen Model＂ quickly became a buzzword in Chinese economic and cultural discourses. Promoters of Wuzhen have claimed that it embodies both tradition and modernity, therefore representing the best of China. While Wuzhen was first reconstructed as a ＂living museum＂ of Chinese cultural tradition to attract tourists, it increasingly started to claim itself as a leading ＂smart town＂ for China＇s future development. Moreover, the so-called Wuzhen Model fits seamlessly into China＇s overall strategy of projecting its soft power both domestically and abroad. The purpose of this paper is to examine how Wuzhen was culturally constructed and how it helped to project China＇s soft power. It also examines how Wuzhen was perceived abroad, focusing primarily on major English-speaking countries including the United States, the United Kingdom, and Australia, to understand its impact on China＇s soft power,
文摘Objective: To explore the analgesic and anti-inflammatory effects of lappaconitine gelata (LA). Methods: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate method in the mouse, and the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were used for investigation on the analgesic and anti-inflammatory effects of LA. Results: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate methods was significantly inhibited by LA. In addition, the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were all significantly suppressed by LA. Conclusion: LA has the analgesic and anti-inflammatory effects.
基金National Natural Science Foundation of China(Grant No.30973628)the National Science and Technology Major Project of China(Grant No.SQ2018ZX090301)
文摘In the present study,we aimed to investigate the chemical constituents and analgesic activity of Aconitum kusnezoffii Reichb. The isolation and purification of components were achieved by a series of chromatography, including silica gel, Sephadex LH-20 and HPLC. By using spectroscopic analysis, their structures were identified. Using PDE-4A as analgesic target, moleculardocking was conducted between isolated compounds by using Schrodinger software. Neoline is a typical non-ester diterpene alkaloid. It was studied by using the mouse torsion body method and hot plate method. A total of 12 diterpene alkaloids were obtainedand identified as Mesaconitine(1), Bewutine (2), Bewudine (3), Songoramine (4), Songorine (5), Neoline (6), Talasamine (7), isotalatizidine (8), Hokbusine A (9), Mesaconine (10), 8-OEt-14-benzoylmesaconine (11), 8-Methoxy-14-benzoyl-beiwutinine (12).Compounds 9 and 12 were isolated from Aconitum kusnezoffii Reichb. for the first time. Twelve diterpenealkaloids could act on the analgesic target. Neoline is a typical non-ester diterpene alkaloid. It had significant analgesic effect. Diterpene alkaloids were the main components of Aconitum kusnezoffiiReichb., and they had good analgesic activity.
