《合生》——用文化营销品牌

暗花底的皮纹纸的封皮．配以淡墨的抽象派图案，看上去很素雅；而“合生”二字的刊名又像是书法字帖临摹，端正而有生气．这便是《合生》月刊留给读者第一印象中的“与众不同”。

从“生X的气”看离合词离析格式的演化过程

从词汇化角度分析"生气"等离合词及其相关格式"生X的气"的产生过程,指出"生X的气"等的来源基础是"吃X的醋"格式。产生的机制是在词汇化与去词汇化的两种演变过程中,汉语整合造词造句和类推的结果。

加味独活寄生合剂对兔膝骨关节炎显微结构的影响

目的:观察加味独活寄生合剂对兔膝骨关节炎显微结构的影响。方法:采用随机数字表法将80只白兔分为正常对照组、模型对照组、阳性对照组和独活寄生组,每组20只。除正常对照组外,其余组均成功制备KOA模型。独活寄生组给予加味独活寄生合剂6.8 mL·kg^(-1)·d^(-1)灌胃,阳性对照组给予盐酸氨基葡萄糖胶囊0.07 g·kg^(-1)·d^(-1)灌胃,正常对照组和模型对照组给予等剂量生理盐水灌胃。在实验干预前、干预第2,4,8周时,对关节软骨形态及显微结构进行观察,并采用番红固绿染色进行Mankins关节软骨评分。结果:与模型对照组比较,独活寄生组膝关节大体观察得到有效改善。模型对照组、阳性对照组、独活寄生组Mankins软骨评分在干预前和干预第2,4,8周均高于正常对照组,且阳性对照组、独活寄生组Mankins软骨评分在干预第2,4,8周均低于模型对照组,差异有统计学意义(P<0.05)。结论:加味独活寄生合剂可有效改善KOA关节软骨显微结构,这可能是其治疗KOA的作用机制。

复方生地合剂治疗系统性红斑狼疮(阴虚内热型)的疗效及安全性评价

目的:研究复方生地合剂在治疗阴虚内热型系统性红斑狼疮中增效减毒、撤减激素用量和改善症状等方面的优势。方法:将60例阴虚内热型系统性红斑狼疮患者随机分为治疗组和对照组,每组30例。均以中、小剂量糖质激素及羟氯喹治疗作为基础用药,治疗组加用复方生地合剂(生地黄30 g、生石膏30 g、忍冬藤30 g),对照组加用安慰剂(淮山药、焦糖)。治疗3个月,比较2组相关指标变化情况。结果:治疗3个月后,治疗组总有效率为83.33%,显著高于对照组的50.00%(P﹤0.05);治疗组中医证候积分、SLE-DAI积分均较治疗前改善(P﹤0.05或P﹤0.01),且治疗组优于对照组(P﹤0.05);治疗组激素用量较治疗前明显减少(P﹤0.05);治疗组抗ds-DNA抗体较治疗前降低(P﹤0.05),对照组治疗前后比较差异无统计学意义(P﹥0.05),且治疗后2组比较差异无统计学意义(P﹥0.05)。治疗组不良反应事件发生率明显低于对照组(P﹤0.05)。结论:复方生地合剂治疗阴虚内热型系统性红斑狼疮疗效明显,可显著降低中医证候积分、SLE-DAI积分,且安全性良好,能显著减少西药的毒副反应及并发症;更利于患者激素的撤减。

CPAP结合肺泡表面活性物质治疗新生儿呼吸窘迫综合征的疗效观察

目的分析CPAP结合肺泡表面活性物质治疗新生儿呼吸窘迫综合征的临床疗效。方法选取我院2016年2月—2017年4月收治的新生儿呼吸窘迫综合征患儿40例作为研究对象。通过抽签法,将其均分为观察组和对照组,每组各20例患儿。对照组患儿采用肺泡表面活性物质进行治疗,观察组患儿采用CPAP结合肺泡表面活性物质进行治疗。结果治疗前,观察组和对照组患者PaO_2、PaCO_2、PaO_2/FiO_2和pH值比较,差异无统计学意义(P>0.05)。治疗后,观察组患者PaO_2、PaCO_2、PaO_2/FiO_2和pH值与对照组比较,差异具有统计学意义(P<0.05)。结论新生儿呼吸窘迫综合征经CPAP结合肺泡表面活性物质治疗疗效确切。

Structures and magnetism of dinuclear Co complexes based on imine derivatives

This study presents the synthesis of three dinuclear cobalt complexes based on three imine derivatives:bis-[4-(2-pyridylmethyleneamino)-phenyl]thioether(L1),bis-[4-(2-pyridylmethyleneamino)-phenyl]ether(L2),and bis-[4-(2-pyridylmethyleneamino)-phenyl]methane(L3).Single-crystal X-ray diffraction analysis reveals that the complexes[Co_(2)(L1)3](ClO_(4))4·2CH_(3)CN(1),[Co_(2)(L2)3](ClO_(4))4·2CH_(3)OH(2),and[Co_(2)(L3)3](ClO_(4))4·2CH_(3)OH(3)all exhibit a dinuclear structure.Magnetic test results show that complex 3 exhibited irreversible SCO behavior induced by loss of solvent at 300 K,with the average Co-N bond length increasing from 0.2139(3)to 0.2153(3)nm.Meanwhile,the desolvated complex 3 exhibited paramagnetic behavior similar to that of complexes 1 and 2.Variable-temperature UV-Vis spectroscopic studies also indicate that complex 3 undergoes a solvent-loss-induced spin-state transition.CCDC:2347354,1(120 K);2347355,2(120 K);2347356,3(120 K);2347357,3(400 K).

Twinning behaviors of Mg-Sn alloy with basal or prismatic Mg_(2)Sn

The Mg-Sn alloys,with basal or prismatic Mg_(2)Sn laths,were employed to reveal the effect of precipitate orientation on twinning behavior quantitatively.The Mg-5wt.%Sn alloys with basal or prismatic Mg_(2)Sn were compressed to study the twinning behaviors.Subsequently,an Orowan strengthening model was developed to quantitatively investigate the critical resolved shear stress(CRSS)increment of precipitates on twinning.The results revealed that the prismatic precipitates hindered the transfer and growth of tensile twins more effectively compared with the basal precipitates.The decreased proportion of tensile twins containing prismatic Mg_(2)Sn might be attributed to a larger CRSS increment for tensile twins compared with that for basal precipitates.The obvious decreased twinning transfer in the alloy with prismatic Mg_(2)Sn could be due to its higher geometrically necessary dislocation and enhanced CRSS of tensile twins.Notably,the prismatic precipitates have a better hindering effect on tensile twins during compression.

A Dual Source Power Based EV Wireless Charging System

Recently,there has been a huge increase in the usage of fuel resources for automobiles which is severely affecting the climate and causing global warming.The use of electric vehicle(EV)is an effective way to protect the environment and reduce travel costs.However,the EV charging system has a single charging source,and the charging rate is limited.In this paper,an EV wireless charging system based on dual source power supply has been developed.It realizes intelligent switching between 12 V photovoltaic output and 220 V AC dual source power,and has wireless transmission function.Based on the proposed power supply architecture,the micro wireless charging model is built,which enables the EV model to store power and realize static and mobile control through the wireless induction charging system.

Censored Composite Conditional Quantile Screening for High-Dimensional Survival Data

In this paper,we introduce the censored composite conditional quantile coefficient(cC-CQC)to rank the relative importance of each predictor in high-dimensional censored regression.The cCCQC takes advantage of all useful information across quantiles and can detect nonlinear effects including interactions and heterogeneity,effectively.Furthermore,the proposed screening method based on cCCQC is robust to the existence of outliers and enjoys the sure screening property.Simulation results demonstrate that the proposed method performs competitively on survival datasets of high-dimensional predictors,particularly when the variables are highly correlated.

Megestrol acetate plus metformin for fertility-sparing treatment of atypical endometrial hyperplasia and early-stage endometrial adenocarcinoma: a prospective study

Objective To evaluate the efficacy of medroxyprogesterone acetate(MA)plus metformin as the primary fertility-sparing treatment for atypical endometrial hyperplasia(AEH)and early-stage grade 1 endometrial adenocarcinoma(G1 EAC)and the recurrence rate after treatment.Methods Sixty patients(aged 20-42 years)with AEH and/or grade 1 EAC limited to the endometrium were enrolled prospectively and randomized into two groups(n=30)to receive oral MA treatment at the daily dose of 160 mg(control)or MA plus oral metformin(850 mg,twice a day)for at least 6 months.The treatment could extend to 12 months until a complete response(CR)was achieved,and follow-up hysteroscopy and curettage were performed every 3 months.For all the patients who achieved CR,endometrial expressions of IGFBP-rP1,p-Akt and p-AMPK were detected immunohistochemically.Results A total of 58 patients completed the treatment.After 9 months of treatment,23(76.7%)patients in the combined treatment group and 20(71.4%)in the control group achieved CR;two patients in the control group achieved CR after converting to the combined treatment.The recurrence rate did not differ significantly between the control group and combined treatment group(30.0%vs 22.7%,P>0.05).Ten(35.7%)patients in the control group experienced significant weight gain of 5.7±6.1 kg,while none of the patients receiving the combined treatment exhibited significant body weight changes.Compared with the control group,the patients receiving the combined treatment showed enhanced endometrial expressions of IGFBP-rP1 and p-AMPK with lowered p-Akt expression.Conclusion Metformin combined with MA may provide an effective option for fertility-sparing treatment of AEH and grade 1 stage IA EAC,and the clinical benefits of metformin for controlling MA-induced weight gain and promoting endometrial expressions of IGFBP-rP1 and p-AMPK while inhibiting p-Akt expression warrants further study.

Study on Daily Change in Photo-physiological Properties of Potato

[Objective]This study was to reveal the photo-physiological properties and suitable climate conditions for potato growth,so as to improve potato quality and yield by making use of the climate resources in Ningxia Hui Autonomous Region,to intensively develop the special agriculture there to enhance the economic benefit of local people.[Method]Using CIRASⅠ-Portable Photosynthesis System,we measured the daily change of photo-physiological indices of potato and further analyzed their relationship with daily weather change,and investigated the impacts of climate factors including atmospheric temperature,humidity,CO2 concentration and light intensity on various physiological indices of potato at key growth stages（flowering stage and stem-swelling stage）.[Results]The results showed that（1） humidity in experimental field assumed a ＂ U＂ type cosine variation curve,while photosynthetically active radiation and atmospheric temperature presented a reverse variation trend;（2） atmospheric CO2 concentration was positively correlated with intercellular CO2 concentration of potato cells,both assumed double ＂ W＂ type curve for daily change;（3） during growth period of potato,in the sunny days with appropriate relative humidity,physiological indices including photosynthetic rate,transpiration rate and stomatal conductance presented similar change law with environmental factor photosynthetically active radiation,all appearing an ＂ M＂ type curve with double peaks and a typical midday depression;（4） midday depression caused by to higher light intensity always appeared simultaneously with the maximum and minimum of air temperature.[Conclusion]Our results provided scientific basis for the large scale production of potato in Ningxia Hui Autonomous Region.

Bioturbation Effects of Benthic Fish on Soil Microorganism of Paddy Field

[Objective]The research aimed to explore the bioturbation effects of benthic fish Misgurnus anguillicaudatus on soil microorganism（microflora,biomass,and special physiological groups） of paddy field.[Method]The experiments were conducted locally and quantitatively in field,using plate count and MPN methods.[Result]In the microflora of paddy soil tested,the quantity of bacteria is the largest,followed by actinomycetes and fungus.Compared with the control paddy fields,in rice-fish paddy fields the quantities of bacteria,actinomycetes and fungus were higher,at significance level P 〈0.05,P 〈0.01,and P 〈0.01 respectively.The microbial biomass C and N in rice-fish paddy fields is remarkably higher than those in control paddy fields,both at significance level P 〈0.01;the microbial biomass P in rice-fish paddy fields is higher than that in control paddy fields,but at significance level P 〈0.05.Benthic fish promotes the growth of soil azotobacter,cellulolytic bacteria,nitrobacteria,sulfur bacteria,and ammonifying bacteria,restricts the reproduction of nitrate reducing bacteria and sulfate reducing bacteria.[Conclusion]The benthic fish had important effects on microflora,microbial biomass,and special microorganism physiological groups of paddy soil,improves the living conditions of soil microorganisms,promotes the soil fertility and bio-chemical activity,which is beneficial for improving the supply ability of soil nutrients such as N,P,S,as well as the efficiency of nutrient utilization.

Comprehensive ecological risk assessment for heavy metal pollutions in three phases in rivers

Literature lacked in providing a comprehensive research on heavy metal detection in aquatic, biological and sedimentary states of rivers. The present study was imparted with all these three components of the river. Heavy metal toxicity or pollution index was used as a tool for ecological risk assessment by considering the single state studies conducted by many researchers. An intensive ecological risk assessment model was constructed and heavy metals were indicated as a serious threat to the environment. The model was applied to determining five toxic heavy metals in three states of the Songhua River. According to the ecological risk index, heavy metal pollution in three phases was categorized as aquatic〉biological〉sedimentary, while the overall descending order of heavy metal ecological risk index was as Cd〉Hg〉As〉Pb〉Cr. Cd and Hg were selected as the priority pollutants of Songhua River.

Localization of stationary pronuclei during conjugation of Paramecium as indicated by immunofluorescence staining

After the third prezygotic division during conjugation of Paramecium caudatum,migratory and stationary pronuclei are produced.The migratory pronuclei remain in the paroral region tightly against the conjugating boundaries;while the stationary pronuclei are located beside the migratory pronuclei.To date,however,it is not clear what causes this close side-by-side localization between migratory and stationary pronuclei.In the current study,immunofluorescence staining with monoclonal antibody of anti-α tubulin indicated that ＂U＂ or ＂V＂ shaped spindles connected the migratory and stationary pronuclei during the third prezygotic division.This observation accounts for the close localization between these two types of pronuclei.

Impact of Fertilizer Types on Photosynthetic and Biological Effects of Direct-seeded Brassica napus at Flowering Stage

[Objective] The aim was to investigate the effects of fertilizer type on di- rect-seeded rapeseed and to explore effective fertilizing. [Method] Four treatments including different types of fertilizers were set in the test. Growth, photosynthesis and chlorophyll fluorescence parameters at flowering stage such as plant height, stem diameter, shoot and root dry matter, net photosynthesis, light energy conversion effi- ciency （Fv/Fm） and SPAD value, were investigated. The effects of fertilizer treat-ments on the yield of rapeseed were evaluated as well. [Result] Both multi-functional fertilizer and controlled release fertilizer could improve plant height, stem diameter, shoot dry matter, SPAD value, net photosynthesis, non-photochemical quenching （NPQ）, etc., which helped increase yield and stress resistance. [Conclusion] Both multi-functional fertilizer and controlled release fertilizer could improve yield significantly while multi-functional fertilizer （MFF） was better than controlled release fertilizer （CRF）.

New details indicated by different stainings during conjugation of ciliated protozoa Paramecium

During conjugation of Paramecium caudatum, nuclear events occur in a scheduled program. Morphological studies on nuclear behavior during conjugation of P. caudatum have been performed since the end of the 19th century. Here we report on new details concerning the conjugation of P. caudatum through the staining of conjugating ceils with protargol, carbol fuchsin solution, Hoechst 33342 and immunofluorescence labeling with monoclonal antibody of anti-a tubulin. 1） The crescent nucleus is a characteristic of the meiotic prophase of P. caudatum, has an unstained area. We stained this area with protargol, which was separated from the chromatin area and was not detected by the other stainings. 2） In regards to the four meiotic products, it has long been considered that only one product enters the paroral cone region （PC） and survives after meiosis. However, our protargol and immunofluorescence labeling results indicated that PC entrance of the meiotic product happened before the completion of meiosis instead of after. 3） In our previous study, protargol staining indicated the presence of a swollen structure around the central part of the ＂U＂ and ＂V＂ shaped spindles connecting the two types of prospective pronuclei. However, immunofluorescence labeling with anti-a tubulin antibodies gave a different image from protargol. All these observations form the basis for further studies of their molecular mechanisms.

Embryological Studies on Facultative Apomixis in Apluda mutica (Gramineae)

A cytological study on Apluda mutica L. revealed that this species was a facultative apomict with 60.74% of apomictic embryo sac formation. Its sexual reproduction exhibited the characteristics of polygonum_type embryo sac formation. After the 3 megaspores at the micropylar end had degenerated, leaving only the chalazal megaspore in the nucellus, a nucellar cell adjacent to the megaspore differentiated into an aposporous initial, which later developed into a panicum_type embryo sac. It was an aposporous 4_nucleate embryo sac without chromosome reduction and composed of an egg, a single synergid and a central cell with 2 polar nuclei. The chalazal megaspore degenerated before the onset of the division in the aposporous initial cell.

Comparison of Growth and Development Traits among Crossbreds of Dorset and Local Sheep Varieties in Gansu Province

In order to improve the meat production performance of local sheep varieties in Gansu Province, Dorset was introduced to crossbreed with the local sheep varieties, including Tan sheep, Small Tail Han sheep and Mongolia sheep. The offspring of different crossbreeding combinations were sampled randomly at different growth stages, and their growth and development traits were measured so as to screen out the best crossbreeding mode. The results showed that under the same crossbreeding mode, the growth rate of F3 was higher than that of F2, and of F2 was higher than that of F1. Among the F3 population, the growth rates of Dorset ×Han and Dorset × Mongolia hybrids were higher. Compared with those of Dorset ×Tan F3 hybrids, the body weights of male and female Dorset × Han and Dorset ×Mongolia F3 hybrids were increased by 5.59%, 4.40%, 5.93% and 3.76%, respectively. Among the F2 population, the growth rates of Dorset × Han and Dorset ×Mongolia hybrids were also higher. The body weights of male and female Dorset ×Han and Dorset × Mongolia F2 hybrids were higher than those of Dorset × Tan ×Han F2 hybrids by 5.99%, 3.67%, 9.80% and 5.00%, respectively. In the F1 population, the growth rates of Dorset × Han and Dorset × Mongolia hybrids were higher.Compared with those of Tan × Han F1 hybrids, the body weights of male and female Dorset × Han and Dorset × Mongolia F1 hybrids were increased by 11.32%,5.22%, 7.60% and 7.20%, respectively. Therefore, in the feeding area of Small Tai Han sheep, Mongolia sheep and Tan sheep, Dorset was the best sire for producing hybrid lambs. The economic benefit of crossbred offspring was obvious.

Corrosion behavior of Ti-Nb-Ta-Zr-Fe alloy for biomedical applications in Ringer's solution

The corrosion resistance of Ti？25Nb？10Ta？1Zr？0.2Fe （mass fraction, %） （TNTZF） alloy in Ringer’s solution at 37 °C was investigated by potentiodynamic polarization measurement. Ti？6Al？4V ELI （Extra low interstitial） alloy was also investigated to make a comparison. The results show that TNTZF alloy has higher corrosion potential, lower corrosion current density, more stable passive current density and wider passive region compared with Ti–6Al–4V ELI alloy, which indicates that TNTZF alloy has better corrosion resistance. In addition, pitting corrosion is observed on the surface passive film of Ti–6Al–4V ELI alloy but is not found on that of TNTZF alloy. The XPS analysis results reveal that the passive film formed on TNTZF alloy is composed of Nb2O5, NbO2, Ta2O5, ZrO2, TiO and Ti2O3oxides in the matrix of TiO2, which makes the passive film more stable and protective than that formed on Ti？6Al？4V ELI alloy and contributes much to its superior corrosion resistance.

Hydrothermal synthesis, characterization and optical properties of La_2Sn_2O_7:Eu^(3+) micro-octahedra

Pyrochlore structure La2Sn2O7：Eu3＋ microcrystals with uniform octahedron shape were successfully synthesized via a hydrothermal route at 180 °C for 36 h. The crystal structure, particle size, morphologies, and optical properties of the as-synthesized products were investigated by XRD, TEM, SEM, EDS, FT-IR, Raman spectroscopy and PL. The effects of pH of precursor solution, precursor concentration, reaction temperature, and time were investigated. The results reveal that pH of the precursor solution not only plays an important role in determining the phase of the as-synthesized products, but also has a significant influence on the morphologies of the samples. High-quality and uniform octahedrons with an average size of about 700 nm could be easily obtained at the pH value of 12. The possible formation mechanism of octahedral-like La2Sn2O7：Eu3＋ microcrystals was briefly proposed. The photoluminescence spectra show that La2Sn2O7：Eu3＋ micro-octahedra display stronger emission in the range of 582-592 nm compared with the samples with other shapes.