The genus Stenochironomus from China,including 10 species,is reviewed.Three species,S.koreanus Borkent,S.maculatus Borkent,and S.totifuscus Sublette are re-described and recorded from China for the first time.One spec...The genus Stenochironomus from China,including 10 species,is reviewed.Three species,S.koreanus Borkent,S.maculatus Borkent,and S.totifuscus Sublette are re-described and recorded from China for the first time.One species misidentification is corrected.A key to the males of Stenochironomus in China is given.展开更多
Homidia hexaseta sp. nov. is reported from Wuyanling National Nature Reserve, Zhejiang Province. This new species is characterized by colour pattern, 6 sutural macrochaeta on dorsal head, smooth seta L1 on labial base...Homidia hexaseta sp. nov. is reported from Wuyanling National Nature Reserve, Zhejiang Province. This new species is characterized by colour pattern, 6 sutural macrochaeta on dorsal head, smooth seta L1 on labial base, seta p4+ present on Th. II, seta a2 present on medial Abd. III, seta B6 as macrochaeta on Abd. IV, setae Ae5-7 present on Abd. IV and subapical tooth of mucro obviously larger than apical one. A key to the Homidia species from Zhejiang Province is also provided.展开更多
Hue-Saturation-Intensity (HSI) color model, a psychologically appealing color model, was employed to visualize uncertainty represented by relative prediction error based on the case of spatial prediction of pH of to...Hue-Saturation-Intensity (HSI) color model, a psychologically appealing color model, was employed to visualize uncertainty represented by relative prediction error based on the case of spatial prediction of pH of topsoil in the peri-urban Beijing. A two-dimensional legend was designed to accompany the visualization-vertical axis (hues) for visualizing the predicted values and horizontal axis (whiteness) for visualizing the prediction error. Moreover, different ways of visualizing uncertainty were briefly reviewed in this paper. This case study indicated that visualization of both predictions and prediction uncertainty offered a possibility to enhance visual exploration of the data uncertainty and to compare different prediction methods or predictions of totally different variables. The whitish region of the visualization map can be simply interpreted as unsatisfactory prediction results, where may need additional samples or more suitable prediction models for a better prediction results.展开更多
Objective Both decreased glomemlar filtration rate (GFR) and arterial stiffness were considered as risk factors for atherosclerosis. Previous studies have suggested the association between central arterial stiffness...Objective Both decreased glomemlar filtration rate (GFR) and arterial stiffness were considered as risk factors for atherosclerosis. Previous studies have suggested the association between central arterial stiffness and the degree of GFR loss. Whether decreased GFR contributes to peripheral artery stiffness remains controversial. Moreover, data analyzed from a cohort of Chinese women are rare. Our aim was to explore the relationship between GFR and regional arterial stiffness in Chinese women. Methods In this cross-sectional study, we randomly recruited 1131 adult women residents with GFR 〉 60 mL/min per 1.73 m2 estimated by the Chinese Modification of Diet in Renal Disease equation from three large communities. Central and peripheral arterial stiffness were estimated simultaneously by measuring carotid-femoral pulse wave velocity (PWVcf) and carotid-radial PWV (PWVcr) using a validated automatic device. Augmentation Index at heart rate 75 beats/minutes (AIx-75) was measured by pulse wave analysis as a composite parameter reflecting both large and distal arterial properties. Results The mean estimated GFR (eGFR) of the study group was 100.05 + 23.26 mL/minute per 1.73 m2. Subjects were grouped by tertiles of eGFR level. PWVef and AIx-75 increased ongoing from the top to the bottom eGFR tertile, while the values of PWVcr were comparable. Both univariate Pearson correlations and multiple stepwise regression analyses showed that eGFR significantly correlated to PWVcf, but not to PWVcr and AJx-75. Conclusions In Chinese women with normal to mildly impaired renal function, decreased eGFR affected carotid-to-femoral rather than carotid-to-radial stiffening. This provides rational to conduct future prospective studies to investigate predictors of atherosclerosis in this population.展开更多
AIM: To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVue-enhancement; and to compare this method with computed tomography (CT) and magnet...AIM: To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVue-enhancement; and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI). METHODS: One hundred and thirty four patients withone focal liver lesion detected in baseline ultrasound (US) were examined with conventional US, contrastenhanced US (n = 134), contrast-enhanced CT (n = 115) and/or dynamic contrast-enhanced MRI (n = 70). The lesions were classified as malignant, benign or indeterminate and the type of lesion was determined. The final diagnosis based on the combined information of all imaging examinations, clinical information and histology (n = 32) was used. Comparisons were made to see whether the addition of contrast-enhanced US led to the improvement of the characterization of doubtful focal liver lesions.RESULTS: In comparison with unenhanced US, SonoVue markedly improves sensitivity and specificity for the characterization (malignant/benign) of focal liver lesions. In comparison with CT and/or dynamic MRI, SonoVue -enhanced sonography applied for characterization of focal liver lesions was 30.2% more sensitive in the recognition of malignancy and 16.1% more specific in the exclusion of malignancy and overall 22.9% more accurate. In the subgroup with confirmative histology available (n = 30), sensitivity was 95.5% (CEUS), 72.2% (CT) and 81.8% (MRI), and specificity was 75.0% (CEUS), 37.5% (CT) and 42.9% (MRI). The sensitivity and specificity of CEUS for the identification of focal nodular hyperplasia (FNH) and hemangiomas was 100% and 87%, resulting in an accuracy of 94.5%.CONCLUSION: SonoVue-enhanced sonography emerges as the most sensitive, ost specific and thus most accurate imaging modality for the characterization of focal liver lesions.展开更多
Epidamaeus variabilis Fujikawa & Fujita, 1985 and Epidamaeus mongolicus Bayartogtokh, 2000 are reported, with redescription, for the first time in China.
Taihu Lake region is one of the most industrialized areas in China, and the surface water is progressively susceptible to anthropogenic pollution. The physicochemical parameters of surface water quality were determine...Taihu Lake region is one of the most industrialized areas in China, and the surface water is progressively susceptible to anthropogenic pollution. The physicochemical parameters of surface water quality were determined at 20 sampling sites in Taihu Lake region, China in spring, summer, autumn, and winter seasons of 2005-2006 to assess the effect of human activities on the surface water quality. Principal component analysis (PCA) and cluster analysis (CA) were used to identify characteristics of the water quality in the studied water bodies. PCA extracted the first three principal components (PCs), explaining 80.84% of the total variance of the raw data. Especially, PC1 (38.91%) was associated with NH 4 -N, total N, soluble reactive phosphorus, and total P. PC2 (22.70%) was characterized by NO 3 -N and temperature. PC3 (19.23%) was mainly associated with pH and dissolved organic carbon. CA showed that streams were influenced by urban residential subsistence and livestock farming contributed significantly to PC1 throughout the year. The streams influenced by farmland runoff contributed most to PC2 in spring and winter compared with other streams. PC3 was affected mainly by aquiculture in spring, rural residential subsistence in summer, and livestock farming in fall and winter seasons. Further analyses showed that farmlands contributed significantly to nitrogen pollution of Taihu Lake, while urban residential subsistence and livestock farming also polluted water quality of Taihu Lake in rainy season. The results would be helpful for the authorities to take sound actions for an effective management of water quality in Taihu Lake region.展开更多
This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and ch...This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.展开更多
Nine families and 12 genera of Chalcidoidea were found in paddy fields from Wuhu, Anhui Province. An illustrated key to the nine families and a general diagnosis of the families are provided.
Various satellite data,JRA-25(Japan reanalysis of 25 years) reanalyzed data and WRF(Weather Research Forecast) model are used to investigate the in situ effect of the ESKF(East China Sea Kuroshio Front) on the MABL(ma...Various satellite data,JRA-25(Japan reanalysis of 25 years) reanalyzed data and WRF(Weather Research Forecast) model are used to investigate the in situ effect of the ESKF(East China Sea Kuroshio Front) on the MABL(marine atmospheric boundary layer).The intensity of the ESKF is most robust from January to April in its annual cycle.The local strong surface northerly/northeasterly winds are observed right over the ESKF in January and in April and the wind speeds decrease upward in the MABL.The thermal wind effect that is derived from the baroclinic MABL forced by the strong SST gradient contributes to the strong surface winds to a large degree.The convergence zone existing along the warm flank of the ESKF is stronger in April than in January corresponding to the steeper SST(sea surface temperature) gradient.The collocations of the cloud cover maximum and precipitation maximum are basically consistent with the convergence zone of the wind field.The clouds develop higher(lower) in the warm(cold) flank of the ESKF due to the less(more) stable stratification in the MABL.The lowest clouds are observed in April on the cold flank of the ESKF and over the Yellow Sea due to the existence of the pronounced temperature inversion.The numerical experiments with smoothed SST are consistent with the results from the ovservations.展开更多
The contamination and environmental risk assessment of the toxic elements in sediments from the middle-downstream (Zhuzhou-Changsha section) of the Xiangjiang River in Hunan Province of China were studied. The results...The contamination and environmental risk assessment of the toxic elements in sediments from the middle-downstream (Zhuzhou-Changsha section) of the Xiangjiang River in Hunan Province of China were studied. The results show that As, Cd, Pb and Zn are major contaminants in sediments, and average concentrations of these elements significantly exceed both the Control Standards for Pollutants in Sludge of China (GB4284-84) for agricultural use in acidic soils and the effect range median (ERM) values. The average concentrations of As, Cd and Pb in the river water slightly exceed the limit of Surface Water Environment Quality Standard (GB3838-2002). The concentrations of As and Cr in depth profiles extensively change, but slight changes are observed in Pb and Zn. Cd and Zn in most sediment samples can easily enter the food-chain and bring possible ecotoxicological risk to organisms living in sediments according to the risk assessment code.展开更多
Objective To investigate the impact of meteorological conditions and PM2.5 on the onset of acute aortic dissection in monsoonal climate. Methods A linear regression analysis was performed in monsoonal climate epidemio...Objective To investigate the impact of meteorological conditions and PM2.5 on the onset of acute aortic dissection in monsoonal climate. Methods A linear regression analysis was performed in monsoonal climate epidemiological survey for a period of four years on the impact of meteorological factors (minimal temperature, mean temperature, maximal temperature, average daily surface temperature, day temperature range, relative humidity, mean wind speed, and atmospheric pressure) and PM2.5 concentration on the daily incidences of acute aortic dissections. Meteorological variables and PM2.5 concentration were retrieved on a daily basis from Beijing Regional Climate Center and the Ministry of Environmental Protection of the People’s Republic of China’s website, and the daily incidences of acute aortic dissections were retrieved from the Clinical Data Analysis and Reporting System in the Emergency and Critical Care Center of Beijing Anzhen Hospital. Results During the study period (from January 2011 to December 2014), 1164 patients were identified as having acute aortic dissections. The corresponding incidences in spring and autumn were 0.96 and 1.00, respectively, which significantly higher than that in summer and winter. The incidences of acute aortic dissection in a day could be predicted by diurnal temperature range (DTR) using the following linear multiple regression models: incidences of acute aortic dissection = 0.543 + 0.025 × DTR. Conclusion This is the first study to show an attributable effect of DTR on acute aortic events in monsoonal climate. Our study confirms that meteorological variables were important factors influencing the incidence of acute aortic dissection.展开更多
Empirical Orthogonal Function (EOF) analysis is used in this study to generate main eigenvector fields of historical temperature for the China Seas (here referring to Chinese marine territories) and adjacent water...Empirical Orthogonal Function (EOF) analysis is used in this study to generate main eigenvector fields of historical temperature for the China Seas (here referring to Chinese marine territories) and adjacent waters from 1930 to 2002 (510 143 profiles). A good temperature profile is reconstructed based on several subsurface in situ temperature observations and the thermocline was estimated using the model. The results show that: 1) For the study area, the former four principal components can explain 95% of the overall variance, and the vertical distribution of temperature is most stable using the in situ temperature observations near the surface. 2) The model verifications based on the observed CTD data from the East China Sea (ECS), South China Sea (SCS) and the areas around Taiwan Island show that the reconstructed profiles have high correlation with the observed ones with the confidence level 〉95%, especially to describe the characteristics of the thermocline well. The average errors between the reconstructed and observed profiles in these three areas are 0.69℃, 0.52℃ and 1.18℃ respectively. It also shows the model RMS error is less than or close to the climatological error. The statistical model can be used to well estimate the temperature profile vertical structure. 3) Comparing the thermocline characteristics between the reconstructed and observed profiles, the results in the ECS show that the average absolute errors are 1.5m, 1.4 m and 0.17~C/m, and the average relative errors are 24.7%, 8.9% and 22.6% for the upper, lower thermocline boundaries and the gradient, respectively. Although the relative errors are obvious, the absolute error is small. In the SCS, the average absolute errors are 4.1 m, 27.7 m and 0.007℃/m, and the average relative errors are 16.1%, 16.8% and 9.5% for the upper, lower thermocline boundaries and the gradient, respectively. The average relative errors are all 〈20%. Although the average absolute error of the lower thermocline boundary is considerable, but contrast to the spatial scale of average depth of the lower thermocline boundary (165 m), the average relative error is small (16.8%). Therefore the model can be used to well estimate the thermocline.展开更多
Migration inhibitory factor-related protein 14 (MRP 14) is one of calcium-binding proteins,referred as S 100A9. The heterodimeric molecule formed by MRP 14 with its partner MRP8 (S 100A8) is the major fatty acid carri...Migration inhibitory factor-related protein 14 (MRP 14) is one of calcium-binding proteins,referred as S 100A9. The heterodimeric molecule formed by MRP 14 with its partner MRP8 (S 100A8) is the major fatty acid carrier in neutrophils.The MRP8/14 complex has been also implicated in the intracellular transport of arachidonic acid and its precursors in keratinocytes. We show here the involvement of MRP14 in human esophageal cancer. In an initial study,mRNA differential display - reverse transcription polymerase chain reaction (DD-PCR) was performed with two esophageal carcinomas,one esophageal adenocarcinoma and matched normal adjacent mucosa. DD-PCR with the arbitrary primer OPA3 showed that one cDNA band was highly expressed in normal tissues,but disappeared or substantially decreased in tumor counterparts. It was later identified to be the 3'-end of migration inhibitory factor-related protein 14 (MRP14).Northern blotting,RT-PCR and Western blotting corroborated the down-regulation of MRP14 in 58/64 squamous cell carcinomas and 2/2 adenocarcinomas as compared with adjacent normal epithelia of the esophagus. MRP14 was undetectable in 3/3 esophageal-carcinoma cell lines. Immunochemistry demonstrated that expression of MRP14 was restricted to normal esophageal epithelia. No mutation was found in the genomic DNA of the MRP14 gene by PCR and directed DNA sequencing. Our finding suggested that the reduction of MRP14 expression is a frequent event in Chinese human esophageal cancer.展开更多
AIM: To investigate the prevalence of advanced polyps in asymptomatic Chinese and to determine the risk of proximal advanced colonic polyps in subjects with and without polyps in the distal colon.METHODS: Data were co...AIM: To investigate the prevalence of advanced polyps in asymptomatic Chinese and to determine the risk of proximal advanced colonic polyps in subjects with and without polyps in the distal colon.METHODS: Data were collected prospectively during colonoscopic examinations performed in 5 973 subjects as part of health evaluation at our unit from December 1997 to December 2003. Polyps were considered advanced, if they were larger than 10 mm or were tubovillous, villous or malignant. Proximal colon was defined as the splenic flexure and more proximal portions of the colon.RESULTS: Colon polyps were detected in 971 (16.3%)subjects (613 males and 358 females) with their mean age being 56.6±10.7 years. Advanced polyps were noted in 199 (3.3%) individuals. Subjects were sub-classified according to the location of polyps into three groups: distal (569, 58.6%), proximal (284, 29.2%), and combined proximal and distal (118, 12.2%) groups. Subjects with advanced polyps in these three groups were 95 (9.8%),56 (5.8%), and 48 (4.9%) respectively. In the 48 subjects with advanced combined polyps, 13 advanced polyps were distributed at the distal colon, 17 at the proximal colon,and 18 at both. Eighteen colon cancers including 12 at sigmoid and 6 at ascending colon were confirmed by final pathology. The relative risk for advanced proximal polyp according to distal findings was 3.1 (95%CI: 1.3-7.4) for hyperplastic polyp, 2.7 (95%CI: 1.4-5.3) for tubular polyp and 13.5 (95%CI: 5.1-35.4) for advanced polyp as compared to that for no polyp. However, 56 (28.2%) of 199 subjects with advanced polyps had no index polyps at the distal colon and might go undetected under sigmoidoscopic screening.CONCLUSION: Although distal lesions can predict the risk of advanced proximal polyps, a substantial portion of Chinese with advanced proximal polyps is not associated with any distal sentinel lesions. These data have implications for screening policy of colon cancers in Taiwan Residents Chinese.展开更多
Based on data collected during the first U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) field campaigns at Shouxian, east- ern China in 2008, the effects of clouds and aerosols on the surf...Based on data collected during the first U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) field campaigns at Shouxian, east- ern China in 2008, the effects of clouds and aerosols on the surface radiation budget during the period Octo- ber-December 2008 were studied. The results revealed that the largest longwave (LW), shortwave (SW), and net Aerosol Radiative Effects (AREs) are 12.7, -37.6, and -24.9 W rn-2, indicating that aerosols have LW warming impact, a strong SW cooling effect, and a net cooling ef- fect on the surface radiation budget at Shouxian during the study period 15 October-15 December 2008. The SW cloud radiative forcing (CRF) is -135.1 W m-2, much cooler than ARE (about 3.6 times), however, the LW CRF is 43.6 W m 2, much warmer than ARE, and resulting in a net CRF of-91.5 W m-2, about 3.7 times of net ARE. These results suggest that the clouds have much stronger LW warming effect and SW cooling effect on the surface radiation budget than AREs. The net surface radiation budget is dominated by SW cooling effect for both ARE and CRE. Furthermore, the precipitatable clouds (PCs) have the largest SW cooling effect and LW warming ef- fect, while optically thin high clouds have the smallest cooling effect and LW warming on the surface radiation budget. Comparing the two selected caseds, CloudSat cloud radar reflectivity agrees very well with the AMF (ARM Mobile Facility) WACR (W-band ARM Cloud Radar) measurements, particularly for cirrus cloud case. These result will provide a ground truth to validate the model simulations in the future.展开更多
This article deals with the motivations and the different sources of value from public to private transactions in Europe, USA and Asia from 2000 to 2007. We determine eight main motivations (tax savings, incentive re...This article deals with the motivations and the different sources of value from public to private transactions in Europe, USA and Asia from 2000 to 2007. We determine eight main motivations (tax savings, incentive realignment, control, free cash flow, growth of prospects, transaction costs, takeover defence and undervaluation). Then, we evaluate the shareholder wealth by measuring the offered premiums and the CAAR (cumulative average abnormal return). Finally, we analyse the impact of public to private to the wealth shareholder. The main sources for firms from going private are incentive realignment, free cash flow (mostly for Asia), the economy of cost transaction and undervaluation. Furthermore, taxation benefit is a source of wealth effects for Asia and family blockholder (for the control hypothesis) is significant for Europe. Premiums and CAAR are the most important for the USA and Asia. The main observation that we have made is that Asia gets the same behavior as the USA.展开更多
A wave flume simulator was used to study internal nitrogen release from the surface sediment collected from Taihu Lake, China. Particulate nitrogen concentrations were positively correlated with the concentrations of ...A wave flume simulator was used to study internal nitrogen release from the surface sediment collected from Taihu Lake, China. Particulate nitrogen concentrations were positively correlated with the concentrations of suspended solids, primarily from surface erosion related to the shear stress and duration of wave action. In response to 4 cm- and 10 cm-high wave production representing waves generated in Taihu Lake by gentle and gusty winds, respectively, the mean dynamic release rate of ammonium (NH4+) from the sediment to the overlying water was 1 × 10-3 mg/(m2.s) and the NH4+ concentration in the overlying water increased by 0.016 mg/L, indicating that waves resulting from strong wind can induce the rapid release of dissolved nitrogen from Taihu Lake sediments. The decrease in interstitial NH4+ concentrations at all sediment depths was associated with an increase in NH4+ concentrations in the overlying water by 0.01 mg/L, showing that sediment below the eroded layer was the main source of internal nitrogen release. Changes in the interstitial dissolved oxygen and NH4+ concentrations showed that wave-induced pore water movement can greatly increase the diffusion rate, and that these 15 cm. Diffusion induced by pore water movement sediment layer in Taihu Lake. effects can influence the sediment to a depth of at least may be very important for the formation of an active展开更多
基金supported by the Zhejiang Provincial Natural Science Foundation of China (Y3100486)the National Natural Science Foundation of China (30570207, J0630963)Fauna of China (FY120100)
文摘The genus Stenochironomus from China,including 10 species,is reviewed.Three species,S.koreanus Borkent,S.maculatus Borkent,and S.totifuscus Sublette are re-described and recorded from China for the first time.One species misidentification is corrected.A key to the males of Stenochironomus in China is given.
基金supported by the Zhejiang Provincial Natural Science Foundation of China (Y3100278, Y3100149) the Zhejiang Provincial Department of Educational Foundation (Y200700872)
文摘Homidia hexaseta sp. nov. is reported from Wuyanling National Nature Reserve, Zhejiang Province. This new species is characterized by colour pattern, 6 sutural macrochaeta on dorsal head, smooth seta L1 on labial base, seta p4+ present on Th. II, seta a2 present on medial Abd. III, seta B6 as macrochaeta on Abd. IV, setae Ae5-7 present on Abd. IV and subapical tooth of mucro obviously larger than apical one. A key to the Homidia species from Zhejiang Province is also provided.
基金Under the auspices of Knowledge Innovation Frontier Project of Institute of Soil Science,Chinese Academy of Sciences(No.ISSASIP0716 )the National Nature Science Foundation of China ( No.40701070,40571065)
文摘Hue-Saturation-Intensity (HSI) color model, a psychologically appealing color model, was employed to visualize uncertainty represented by relative prediction error based on the case of spatial prediction of pH of topsoil in the peri-urban Beijing. A two-dimensional legend was designed to accompany the visualization-vertical axis (hues) for visualizing the predicted values and horizontal axis (whiteness) for visualizing the prediction error. Moreover, different ways of visualizing uncertainty were briefly reviewed in this paper. This case study indicated that visualization of both predictions and prediction uncertainty offered a possibility to enhance visual exploration of the data uncertainty and to compare different prediction methods or predictions of totally different variables. The whitish region of the visualization map can be simply interpreted as unsatisfactory prediction results, where may need additional samples or more suitable prediction models for a better prediction results.
文摘Objective Both decreased glomemlar filtration rate (GFR) and arterial stiffness were considered as risk factors for atherosclerosis. Previous studies have suggested the association between central arterial stiffness and the degree of GFR loss. Whether decreased GFR contributes to peripheral artery stiffness remains controversial. Moreover, data analyzed from a cohort of Chinese women are rare. Our aim was to explore the relationship between GFR and regional arterial stiffness in Chinese women. Methods In this cross-sectional study, we randomly recruited 1131 adult women residents with GFR 〉 60 mL/min per 1.73 m2 estimated by the Chinese Modification of Diet in Renal Disease equation from three large communities. Central and peripheral arterial stiffness were estimated simultaneously by measuring carotid-femoral pulse wave velocity (PWVcf) and carotid-radial PWV (PWVcr) using a validated automatic device. Augmentation Index at heart rate 75 beats/minutes (AIx-75) was measured by pulse wave analysis as a composite parameter reflecting both large and distal arterial properties. Results The mean estimated GFR (eGFR) of the study group was 100.05 + 23.26 mL/minute per 1.73 m2. Subjects were grouped by tertiles of eGFR level. PWVef and AIx-75 increased ongoing from the top to the bottom eGFR tertile, while the values of PWVcr were comparable. Both univariate Pearson correlations and multiple stepwise regression analyses showed that eGFR significantly correlated to PWVcf, but not to PWVcr and AJx-75. Conclusions In Chinese women with normal to mildly impaired renal function, decreased eGFR affected carotid-to-femoral rather than carotid-to-radial stiffening. This provides rational to conduct future prospective studies to investigate predictors of atherosclerosis in this population.
文摘AIM: To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVue-enhancement; and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI). METHODS: One hundred and thirty four patients withone focal liver lesion detected in baseline ultrasound (US) were examined with conventional US, contrastenhanced US (n = 134), contrast-enhanced CT (n = 115) and/or dynamic contrast-enhanced MRI (n = 70). The lesions were classified as malignant, benign or indeterminate and the type of lesion was determined. The final diagnosis based on the combined information of all imaging examinations, clinical information and histology (n = 32) was used. Comparisons were made to see whether the addition of contrast-enhanced US led to the improvement of the characterization of doubtful focal liver lesions.RESULTS: In comparison with unenhanced US, SonoVue markedly improves sensitivity and specificity for the characterization (malignant/benign) of focal liver lesions. In comparison with CT and/or dynamic MRI, SonoVue -enhanced sonography applied for characterization of focal liver lesions was 30.2% more sensitive in the recognition of malignancy and 16.1% more specific in the exclusion of malignancy and overall 22.9% more accurate. In the subgroup with confirmative histology available (n = 30), sensitivity was 95.5% (CEUS), 72.2% (CT) and 81.8% (MRI), and specificity was 75.0% (CEUS), 37.5% (CT) and 42.9% (MRI). The sensitivity and specificity of CEUS for the identification of focal nodular hyperplasia (FNH) and hemangiomas was 100% and 87%, resulting in an accuracy of 94.5%.CONCLUSION: SonoVue-enhanced sonography emerges as the most sensitive, ost specific and thus most accurate imaging modality for the characterization of focal liver lesions.
文摘Epidamaeus variabilis Fujikawa & Fujita, 1985 and Epidamaeus mongolicus Bayartogtokh, 2000 are reported, with redescription, for the first time in China.
基金Project supported by the Knowledge Innovation Key Project of the Chinese Academy of Sciences (No. KZCX1-YW-14-5)the National Natural Science Foundation of China (No. 30600086)
文摘Taihu Lake region is one of the most industrialized areas in China, and the surface water is progressively susceptible to anthropogenic pollution. The physicochemical parameters of surface water quality were determined at 20 sampling sites in Taihu Lake region, China in spring, summer, autumn, and winter seasons of 2005-2006 to assess the effect of human activities on the surface water quality. Principal component analysis (PCA) and cluster analysis (CA) were used to identify characteristics of the water quality in the studied water bodies. PCA extracted the first three principal components (PCs), explaining 80.84% of the total variance of the raw data. Especially, PC1 (38.91%) was associated with NH 4 -N, total N, soluble reactive phosphorus, and total P. PC2 (22.70%) was characterized by NO 3 -N and temperature. PC3 (19.23%) was mainly associated with pH and dissolved organic carbon. CA showed that streams were influenced by urban residential subsistence and livestock farming contributed significantly to PC1 throughout the year. The streams influenced by farmland runoff contributed most to PC2 in spring and winter compared with other streams. PC3 was affected mainly by aquiculture in spring, rural residential subsistence in summer, and livestock farming in fall and winter seasons. Further analyses showed that farmlands contributed significantly to nitrogen pollution of Taihu Lake, while urban residential subsistence and livestock farming also polluted water quality of Taihu Lake in rainy season. The results would be helpful for the authorities to take sound actions for an effective management of water quality in Taihu Lake region.
文摘This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.
基金supported by the Natural Science Foundation of Education Department of Anhui Province (KJ2011A133)the Science Project of Wuhu City (2010-6-11)
文摘Nine families and 12 genera of Chalcidoidea were found in paddy fields from Wuhu, Anhui Province. An illustrated key to the nine families and a general diagnosis of the families are provided.
基金supported by the National Natural Science Foundation of China (No.40975003)the Ph.D.Programs Foundation of Ministry of Education of China (No.20090132110008)GYHY(QX)2007-6-31
文摘Various satellite data,JRA-25(Japan reanalysis of 25 years) reanalyzed data and WRF(Weather Research Forecast) model are used to investigate the in situ effect of the ESKF(East China Sea Kuroshio Front) on the MABL(marine atmospheric boundary layer).The intensity of the ESKF is most robust from January to April in its annual cycle.The local strong surface northerly/northeasterly winds are observed right over the ESKF in January and in April and the wind speeds decrease upward in the MABL.The thermal wind effect that is derived from the baroclinic MABL forced by the strong SST gradient contributes to the strong surface winds to a large degree.The convergence zone existing along the warm flank of the ESKF is stronger in April than in January corresponding to the steeper SST(sea surface temperature) gradient.The collocations of the cloud cover maximum and precipitation maximum are basically consistent with the convergence zone of the wind field.The clouds develop higher(lower) in the warm(cold) flank of the ESKF due to the less(more) stable stratification in the MABL.The lowest clouds are observed in April on the cold flank of the ESKF and over the Yellow Sea due to the existence of the pronounced temperature inversion.The numerical experiments with smoothed SST are consistent with the results from the ovservations.
基金Project (20507022) supported by the National Natural Science Foundation of ChinaProject (EREH050303) supported by the Foundation of Ministry of Education Key Laboratory of Environmental Remediation and Ecosystem Health
文摘The contamination and environmental risk assessment of the toxic elements in sediments from the middle-downstream (Zhuzhou-Changsha section) of the Xiangjiang River in Hunan Province of China were studied. The results show that As, Cd, Pb and Zn are major contaminants in sediments, and average concentrations of these elements significantly exceed both the Control Standards for Pollutants in Sludge of China (GB4284-84) for agricultural use in acidic soils and the effect range median (ERM) values. The average concentrations of As, Cd and Pb in the river water slightly exceed the limit of Surface Water Environment Quality Standard (GB3838-2002). The concentrations of As and Cr in depth profiles extensively change, but slight changes are observed in Pb and Zn. Cd and Zn in most sediment samples can easily enter the food-chain and bring possible ecotoxicological risk to organisms living in sediments according to the risk assessment code.
基金This study was supported by National Science Foundation Council of China (No.81700383), Jilin Provincial Industrial Innovation Special Fund Project (No.2016C041), Beijing Natural Science Foundation of China (8152019), Beijing Municipal Science and Technology of Chinese Medicine Development Funds Youth Research Project (No. QN2016-20), and Basic-Clinical Scientific Research Cooperation of Capital Medical University fund (No.17JL72). The authors declare no conflict of interest.
文摘Objective To investigate the impact of meteorological conditions and PM2.5 on the onset of acute aortic dissection in monsoonal climate. Methods A linear regression analysis was performed in monsoonal climate epidemiological survey for a period of four years on the impact of meteorological factors (minimal temperature, mean temperature, maximal temperature, average daily surface temperature, day temperature range, relative humidity, mean wind speed, and atmospheric pressure) and PM2.5 concentration on the daily incidences of acute aortic dissections. Meteorological variables and PM2.5 concentration were retrieved on a daily basis from Beijing Regional Climate Center and the Ministry of Environmental Protection of the People’s Republic of China’s website, and the daily incidences of acute aortic dissections were retrieved from the Clinical Data Analysis and Reporting System in the Emergency and Critical Care Center of Beijing Anzhen Hospital. Results During the study period (from January 2011 to December 2014), 1164 patients were identified as having acute aortic dissections. The corresponding incidences in spring and autumn were 0.96 and 1.00, respectively, which significantly higher than that in summer and winter. The incidences of acute aortic dissection in a day could be predicted by diurnal temperature range (DTR) using the following linear multiple regression models: incidences of acute aortic dissection = 0.543 + 0.025 × DTR. Conclusion This is the first study to show an attributable effect of DTR on acute aortic events in monsoonal climate. Our study confirms that meteorological variables were important factors influencing the incidence of acute aortic dissection.
基金Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No.KZCX-3W-222 KZCX2-YW-Q11-02)+1 种基金National Basic Research Program of China (No.2007CB411802 2006CB403601)
文摘Empirical Orthogonal Function (EOF) analysis is used in this study to generate main eigenvector fields of historical temperature for the China Seas (here referring to Chinese marine territories) and adjacent waters from 1930 to 2002 (510 143 profiles). A good temperature profile is reconstructed based on several subsurface in situ temperature observations and the thermocline was estimated using the model. The results show that: 1) For the study area, the former four principal components can explain 95% of the overall variance, and the vertical distribution of temperature is most stable using the in situ temperature observations near the surface. 2) The model verifications based on the observed CTD data from the East China Sea (ECS), South China Sea (SCS) and the areas around Taiwan Island show that the reconstructed profiles have high correlation with the observed ones with the confidence level 〉95%, especially to describe the characteristics of the thermocline well. The average errors between the reconstructed and observed profiles in these three areas are 0.69℃, 0.52℃ and 1.18℃ respectively. It also shows the model RMS error is less than or close to the climatological error. The statistical model can be used to well estimate the temperature profile vertical structure. 3) Comparing the thermocline characteristics between the reconstructed and observed profiles, the results in the ECS show that the average absolute errors are 1.5m, 1.4 m and 0.17~C/m, and the average relative errors are 24.7%, 8.9% and 22.6% for the upper, lower thermocline boundaries and the gradient, respectively. Although the relative errors are obvious, the absolute error is small. In the SCS, the average absolute errors are 4.1 m, 27.7 m and 0.007℃/m, and the average relative errors are 16.1%, 16.8% and 9.5% for the upper, lower thermocline boundaries and the gradient, respectively. The average relative errors are all 〈20%. Although the average absolute error of the lower thermocline boundary is considerable, but contrast to the spatial scale of average depth of the lower thermocline boundary (165 m), the average relative error is small (16.8%). Therefore the model can be used to well estimate the thermocline.
基金supported by State Key Basic Research programme of China(G1998051205)National Key Technologies R&D Programme of China(2002BA711A06)+2 种基金The National High Technology Research and Development Program of China(2001AA221151)National Natural Science Foundation of China(30125026)Doctoral Program Fund of China(20010023016).
文摘Migration inhibitory factor-related protein 14 (MRP 14) is one of calcium-binding proteins,referred as S 100A9. The heterodimeric molecule formed by MRP 14 with its partner MRP8 (S 100A8) is the major fatty acid carrier in neutrophils.The MRP8/14 complex has been also implicated in the intracellular transport of arachidonic acid and its precursors in keratinocytes. We show here the involvement of MRP14 in human esophageal cancer. In an initial study,mRNA differential display - reverse transcription polymerase chain reaction (DD-PCR) was performed with two esophageal carcinomas,one esophageal adenocarcinoma and matched normal adjacent mucosa. DD-PCR with the arbitrary primer OPA3 showed that one cDNA band was highly expressed in normal tissues,but disappeared or substantially decreased in tumor counterparts. It was later identified to be the 3'-end of migration inhibitory factor-related protein 14 (MRP14).Northern blotting,RT-PCR and Western blotting corroborated the down-regulation of MRP14 in 58/64 squamous cell carcinomas and 2/2 adenocarcinomas as compared with adjacent normal epithelia of the esophagus. MRP14 was undetectable in 3/3 esophageal-carcinoma cell lines. Immunochemistry demonstrated that expression of MRP14 was restricted to normal esophageal epithelia. No mutation was found in the genomic DNA of the MRP14 gene by PCR and directed DNA sequencing. Our finding suggested that the reduction of MRP14 expression is a frequent event in Chinese human esophageal cancer.
文摘AIM: To investigate the prevalence of advanced polyps in asymptomatic Chinese and to determine the risk of proximal advanced colonic polyps in subjects with and without polyps in the distal colon.METHODS: Data were collected prospectively during colonoscopic examinations performed in 5 973 subjects as part of health evaluation at our unit from December 1997 to December 2003. Polyps were considered advanced, if they were larger than 10 mm or were tubovillous, villous or malignant. Proximal colon was defined as the splenic flexure and more proximal portions of the colon.RESULTS: Colon polyps were detected in 971 (16.3%)subjects (613 males and 358 females) with their mean age being 56.6±10.7 years. Advanced polyps were noted in 199 (3.3%) individuals. Subjects were sub-classified according to the location of polyps into three groups: distal (569, 58.6%), proximal (284, 29.2%), and combined proximal and distal (118, 12.2%) groups. Subjects with advanced polyps in these three groups were 95 (9.8%),56 (5.8%), and 48 (4.9%) respectively. In the 48 subjects with advanced combined polyps, 13 advanced polyps were distributed at the distal colon, 17 at the proximal colon,and 18 at both. Eighteen colon cancers including 12 at sigmoid and 6 at ascending colon were confirmed by final pathology. The relative risk for advanced proximal polyp according to distal findings was 3.1 (95%CI: 1.3-7.4) for hyperplastic polyp, 2.7 (95%CI: 1.4-5.3) for tubular polyp and 13.5 (95%CI: 5.1-35.4) for advanced polyp as compared to that for no polyp. However, 56 (28.2%) of 199 subjects with advanced polyps had no index polyps at the distal colon and might go undetected under sigmoidoscopic screening.CONCLUSION: Although distal lesions can predict the risk of advanced proximal polyps, a substantial portion of Chinese with advanced proximal polyps is not associated with any distal sentinel lesions. These data have implications for screening policy of colon cancers in Taiwan Residents Chinese.
基金sponsored by the U.S. DOE Office of Energy Research,Office of Health and Environmental Research,Environmental Sciences Divisionthe support of DOE Atmospheric System Research(ASR) project with award number DE-SC0008468 at University of North Dakota+3 种基金funded by the Key Laboratory of Meteorological Disaster of Ministry of Education (KLME)(KLME1206)the National Natural Science Foundation of China(41275043 and 41175035)a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)the National Basic Research Program of China(973 Program,2013CB955800) at Beijing Normal University
文摘Based on data collected during the first U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) field campaigns at Shouxian, east- ern China in 2008, the effects of clouds and aerosols on the surface radiation budget during the period Octo- ber-December 2008 were studied. The results revealed that the largest longwave (LW), shortwave (SW), and net Aerosol Radiative Effects (AREs) are 12.7, -37.6, and -24.9 W rn-2, indicating that aerosols have LW warming impact, a strong SW cooling effect, and a net cooling ef- fect on the surface radiation budget at Shouxian during the study period 15 October-15 December 2008. The SW cloud radiative forcing (CRF) is -135.1 W m-2, much cooler than ARE (about 3.6 times), however, the LW CRF is 43.6 W m 2, much warmer than ARE, and resulting in a net CRF of-91.5 W m-2, about 3.7 times of net ARE. These results suggest that the clouds have much stronger LW warming effect and SW cooling effect on the surface radiation budget than AREs. The net surface radiation budget is dominated by SW cooling effect for both ARE and CRE. Furthermore, the precipitatable clouds (PCs) have the largest SW cooling effect and LW warming ef- fect, while optically thin high clouds have the smallest cooling effect and LW warming on the surface radiation budget. Comparing the two selected caseds, CloudSat cloud radar reflectivity agrees very well with the AMF (ARM Mobile Facility) WACR (W-band ARM Cloud Radar) measurements, particularly for cirrus cloud case. These result will provide a ground truth to validate the model simulations in the future.
文摘This article deals with the motivations and the different sources of value from public to private transactions in Europe, USA and Asia from 2000 to 2007. We determine eight main motivations (tax savings, incentive realignment, control, free cash flow, growth of prospects, transaction costs, takeover defence and undervaluation). Then, we evaluate the shareholder wealth by measuring the offered premiums and the CAAR (cumulative average abnormal return). Finally, we analyse the impact of public to private to the wealth shareholder. The main sources for firms from going private are incentive realignment, free cash flow (mostly for Asia), the economy of cost transaction and undervaluation. Furthermore, taxation benefit is a source of wealth effects for Asia and family blockholder (for the control hypothesis) is significant for Europe. Premiums and CAAR are the most important for the USA and Asia. The main observation that we have made is that Asia gets the same behavior as the USA.
基金Supported by the National Natural Science Foundation of China(Nos.41101458, 40825004,40871095,40801200)the Major Project for National Science and Technology Development(No.2010ZX03006-006)the "100-Talent Project" of Chinese Academy of Sciences,China(No.YOBROB045)
文摘A wave flume simulator was used to study internal nitrogen release from the surface sediment collected from Taihu Lake, China. Particulate nitrogen concentrations were positively correlated with the concentrations of suspended solids, primarily from surface erosion related to the shear stress and duration of wave action. In response to 4 cm- and 10 cm-high wave production representing waves generated in Taihu Lake by gentle and gusty winds, respectively, the mean dynamic release rate of ammonium (NH4+) from the sediment to the overlying water was 1 × 10-3 mg/(m2.s) and the NH4+ concentration in the overlying water increased by 0.016 mg/L, indicating that waves resulting from strong wind can induce the rapid release of dissolved nitrogen from Taihu Lake sediments. The decrease in interstitial NH4+ concentrations at all sediment depths was associated with an increase in NH4+ concentrations in the overlying water by 0.01 mg/L, showing that sediment below the eroded layer was the main source of internal nitrogen release. Changes in the interstitial dissolved oxygen and NH4+ concentrations showed that wave-induced pore water movement can greatly increase the diffusion rate, and that these 15 cm. Diffusion induced by pore water movement sediment layer in Taihu Lake. effects can influence the sediment to a depth of at least may be very important for the formation of an active