AIMTo compare the efficacy and safety of cold snare polypectomy (CSP) and hot forceps biopsy (HFB) for diminutive colorectal polyps.METHODSThis prospective, randomized single-center clinical trial included consecutive...AIMTo compare the efficacy and safety of cold snare polypectomy (CSP) and hot forceps biopsy (HFB) for diminutive colorectal polyps.METHODSThis prospective, randomized single-center clinical trial included consecutive patients ≥ 20 years of age with diminutive colorectal polyps 3-5 mm from December 2014 to October 2015. The primary outcome measures were en-bloc resection (endoscopic evaluation) and complete resection rates (pathological evaluation). The secondary outcome measures were the immediate bleeding or immediate perforation rate after polypectomy, delayed bleeding or delayed perforation rate after polypectomy, use of clipping for bleeding or perforation, and polyp retrieval rate. Prophylactic clipping after polyp removal wasn’t routinely performed.RESULTSTwo hundred eight patients were randomized into the CSP (102), HFB (106) and 283 polyps were evaluated (CSP: 148, HFB: 135). The en-bloc resection rate was significantly higher with CSP than with HFB [99.3% (147/148) vs 80.0% (108/135), P < 0.0001]. The complete resection rate was significantly higher with CSP than with HFB [80.4% (119/148) vs 47.4% (64/135), P < 0.0001]. The immediate bleeding rate was similar between the groups [8.6% (13/148) vs 8.1% (11/135), P = 1.000], and endoscopic hemostasis with hemoclips was successful in all cases. No cases of perforation or delayed bleeding occurred. The rate of severe tissue injury to the pathological specimen was higher HFB than CSP [52.6% (71/135) vs 1.3% (2/148), P < 0.0001]. Polyp retrieval failure was encountered CSP (7), HFB (2).CONCLUSIONCSP is more effective than HFB for resecting diminutive polyps. Further long-term follow-up study is required.展开更多
The physical models of the outer and inner half coil jackets were simplified to two types of coiled ducts.The mathematic models of incompressible fluid at the condition of laminar flow and heat transfer in the two typ...The physical models of the outer and inner half coil jackets were simplified to two types of coiled ducts.The mathematic models of incompressible fluid at the condition of laminar flow and heat transfer in the two types of jackets for cooling process reactor were set up and solved by the semi-implicit method for pressure linked equa-tions consistent （SIMPLEC） algorithm based on a control volume method.The flow and temperature fields were given and the effects of Dean and Prandtl numbers on flow and heat transfer were studied.The results show that flow in the inner half coil jacket is found to exhibit transition of secondary flow pattern from two vortices to four vortices when the Dean number increases,but that in the outer half coil jacket is not found.The critical Dean num-ber is about 96.The inner half coil jacket has stronger heat transfer ability than the outer half coil jacket and this superiority is more evident with larger Prandtl number.However,as the Dean number is greater than 105,the flow resistance enhances more severely in the inner jacket than the outer jacket.For both jackets,the centers of the heated wall are the poorest for heat transfer.展开更多
For most of circular graph the length of the minimum cycle basis is given. For the others a bound of the length of the minimum cycle basis is given and the given bound is reached.
文摘AIMTo compare the efficacy and safety of cold snare polypectomy (CSP) and hot forceps biopsy (HFB) for diminutive colorectal polyps.METHODSThis prospective, randomized single-center clinical trial included consecutive patients ≥ 20 years of age with diminutive colorectal polyps 3-5 mm from December 2014 to October 2015. The primary outcome measures were en-bloc resection (endoscopic evaluation) and complete resection rates (pathological evaluation). The secondary outcome measures were the immediate bleeding or immediate perforation rate after polypectomy, delayed bleeding or delayed perforation rate after polypectomy, use of clipping for bleeding or perforation, and polyp retrieval rate. Prophylactic clipping after polyp removal wasn’t routinely performed.RESULTSTwo hundred eight patients were randomized into the CSP (102), HFB (106) and 283 polyps were evaluated (CSP: 148, HFB: 135). The en-bloc resection rate was significantly higher with CSP than with HFB [99.3% (147/148) vs 80.0% (108/135), P < 0.0001]. The complete resection rate was significantly higher with CSP than with HFB [80.4% (119/148) vs 47.4% (64/135), P < 0.0001]. The immediate bleeding rate was similar between the groups [8.6% (13/148) vs 8.1% (11/135), P = 1.000], and endoscopic hemostasis with hemoclips was successful in all cases. No cases of perforation or delayed bleeding occurred. The rate of severe tissue injury to the pathological specimen was higher HFB than CSP [52.6% (71/135) vs 1.3% (2/148), P < 0.0001]. Polyp retrieval failure was encountered CSP (7), HFB (2).CONCLUSIONCSP is more effective than HFB for resecting diminutive polyps. Further long-term follow-up study is required.
基金Supported by the National Key Technologies Research and Development Program during the 10th Five-year Plan Period(2004BA319B1)the Educational Commission of Liaoning Province of China(2008S117)
文摘The physical models of the outer and inner half coil jackets were simplified to two types of coiled ducts.The mathematic models of incompressible fluid at the condition of laminar flow and heat transfer in the two types of jackets for cooling process reactor were set up and solved by the semi-implicit method for pressure linked equa-tions consistent （SIMPLEC） algorithm based on a control volume method.The flow and temperature fields were given and the effects of Dean and Prandtl numbers on flow and heat transfer were studied.The results show that flow in the inner half coil jacket is found to exhibit transition of secondary flow pattern from two vortices to four vortices when the Dean number increases,but that in the outer half coil jacket is not found.The critical Dean num-ber is about 96.The inner half coil jacket has stronger heat transfer ability than the outer half coil jacket and this superiority is more evident with larger Prandtl number.However,as the Dean number is greater than 105,the flow resistance enhances more severely in the inner jacket than the outer jacket.For both jackets,the centers of the heated wall are the poorest for heat transfer.
基金Supported by the NSF of Renmin University of China
文摘For most of circular graph the length of the minimum cycle basis is given. For the others a bound of the length of the minimum cycle basis is given and the given bound is reached.
