Neurenteric cysts are extremely rare congenital anomalies, often presenting in the first 5 years of life, and are caused by an incomplete separation of the notochord from the foregut during the third week of embryogen...Neurenteric cysts are extremely rare congenital anomalies, often presenting in the first 5 years of life, and are caused by an incomplete separation of the notochord from the foregut during the third week of embryogenesis. They are frequently accompanied with spinal or gastrointestinal abnormalities, but the latter may be absent in adults. Although usually located in the thorax, neurenteric cysts may be found along the entire spine. We present a 24-year-old woman admitted for epigastric pain, nausea, vomiting, low grade fever and leucocytosis. She underwent cystgastrostomy for a Ioculated cyst of the distal pancreas at the age of 4 years, which recurred when she was at the age of 11 years. Ultrasound and computer tomograghy （CT） scan revealed a 16 cmx 15 cm cystic mass in the body and tail of pancreas, with a 6-7 mm thickened wall. Laboratory data and chest X-ray were normal and spinal radiographs did not show any structural abnormalities. The patient underwent a complete cyst excision, and after an uneventful recovery, remained symptom-free without recurrence during the 5-year follow-up. The cyst was found to contain 1200 mL of pale viscous fluid. It was covered by a primitive singlelayered cuboidal epithelium, along with specialized antral glandular parenchyma and hypoplastic primitive gastric mucosa. Focal glandular groups resembling those of the body of the stomach were also seen. In addition, ciliary respiratory epithelium, foci of squamous metaplasia and mucinous glands were present. The wall of the cyst contained a muscular layer, neuroglial tissue with plexogenic nerve fascicles, Paccini corpuscle-like structures, hyperplastic neuroganglionar elements and occasional psammomatous bodies, as well as fibroblast-like areas of surrounding stroma. Cartilagenous tissue was not found in any part of the cyst. Immunohistochemistry confirmed the presence of neurogenic elements marked by S-100, GFAP, NF and NSE. The gastric epithelium showed mostly CK7 and EMA immunoexpression, and the respiratory epithelium revealed a CK8 and CK18 immunoprofile without CK 10/13 positive elements, though neither CEA or AFP positive cells were found. To our knowledge, this is the first reported case of an abdominally located neurenteric cyst with no associated spinal anomalies.展开更多
To improve current understanding of the water cycle,energy partitioning and CO2 exchange over hilly zone vegetative land surfaces in the subtropical monsoon environment of southern China,a long-term field experiment o...To improve current understanding of the water cycle,energy partitioning and CO2 exchange over hilly zone vegetative land surfaces in the subtropical monsoon environment of southern China,a long-term field experiment observatory was set up at Ningxiang,eastern Hunan Province.This paper presents a preliminary analysis of the field observations at the observatory collected from August to November 2012.Results show that significant diurnal variations in soil temperature occur only in shallow soil layers(0.05,0.10,and 0.20 m),and that heavy rainfall affects soil moisture in the deep layers(≥ 0.40 m).During the experimental period,significant diurnal variations in albedo,radiation components,energy components,and CO2 flux were observed,but little seasonal variation.Strong photosynthesis in the vegetation canopy enhanced the CO2 absorption and the latent heat released in daylight hours;Latent heat of evaporation was the main consumer of available energy in late summer.Because the field experiment data are demonstrably reliable,the observatory will provide reliable long-term measurements for future investigations of the land-atmosphere interaction over hilly land surfaces in the subtropical monsoon region of southern China.展开更多
AIM: To examine the protective effect of green tea extract (GT) on hepatic fi brosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats.METHODS: HSC-T6, a rat hepatic stellate cell line, was used as an in ...AIM: To examine the protective effect of green tea extract (GT) on hepatic fi brosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats.METHODS: HSC-T6, a rat hepatic stellate cell line, was used as an in vitro assay system. Cell proliferation, collagen content, and type 1 collagen expression were examined in activated HSC-T6 cells. Collagen was determined by estimating the hydroxyproline content. In rats with DMN-induced hepatic fi brosis, serum aspartate aminotransferase and alanine aminotransferase concentrations, liver hydroxyproline and lipid peroxides were determined. Pathologic changes were examined by hematoxylin & eosin staining.RESULTS: GT administration prevented the development of hepatic fibrosis in the rat model of DMN-induced liver fi brosis. These results were confi rmed both by liver histology and by quantitative measurement of hepatic hydroxyproline content, a marker of liver collagen deposition. Accordingly, inhibition of proliferation, reduced collagen deposition, and type 1 collagen expression were observed in activated HSC-T6 cells following GT treatment. These results imply that GT reduced the proliferation of activated HSC and down regulated the collagen content and expression of collagen type 1, thereby ameliorating hepatic fibrosis.CONCLUSION: This study demonstrates that greentea administration can effectively improve liver fibrosis caused by DMN, and may be used as a therapeutic option and preventive measure against hepatic f ibrosis.展开更多
The non-linear relationships between the contents of ginsenoside Rg 1, Rb 1, Rd and Panax notoginseng saponins(PNS) in Panax notoginseng root herb and the near infrared(NIR) diffuse reflectance spectra of the herb wer...The non-linear relationships between the contents of ginsenoside Rg 1, Rb 1, Rd and Panax notoginseng saponins(PNS) in Panax notoginseng root herb and the near infrared(NIR) diffuse reflectance spectra of the herb were established by means of artificial neural networks(ANNs). Four three-layered perception feed-forward networks were trained with an error back-propagation algorithm. The significant principal components of the NIR spectral data matrix were utilized as the input of the networks. The networks architecture and parameters were selected so as to offer less prediction errors. Relative prediction errors for Rg 1, Rb 1, Rd and PNS obtained with the optimum ANN models were 8.99%, 6.54%, 8.29%, and 5.17%, respectively, which were superior to those obtained with PLSR methods. It is verified that ANN is a suitable approach to model this complex non-linearity. The developed method is fast, non-destructive and accurate and it provides a new efficient approach for determining the active components in the complex system of natural herbs.展开更多
A validation study of land surface temperature (LST) obtained from the Ka band (37 GHz) vertically polarized brightness temperature over northern China is presented.The remotely sensed LST derived jointly by the Vrije...A validation study of land surface temperature (LST) obtained from the Ka band (37 GHz) vertically polarized brightness temperature over northern China is presented.The remotely sensed LST derived jointly by the Vrije Universiteit Amsterdam and the NASA Goddard Space Flight Center (VUA-NASA) from the Advanced Microwave Scanning Radiometer-Earth Observing System (AMSR-E) were compared to the daily in-situ top soil temperature/infrared surface temperature observations from eleven/three Enhanced Coordinated Observation stations in arid and semi-arid regions of northern China.The VUA-NASA LST from the descending path exhibited a stronger correspondence to the in-situ infrared surface temperature than soil temperature observations,whereas correlations (R 2) of the latter ranged from 0.41 to 0.86.Meanwhile,the ascending overpass LST was generally warmer than the in-situ soil temperature observations at all stations,and the correlation (R 2) was between 0.07 and 0.72.Furthermore,the correlation of the descending path was generally greater than that of the ascending path at the same station.The descending path VUA-NASA LST was sensitive to precipitation and presented good agreement with ground temperature dynamics.The analyses demonstrated that the descending overpass LST was reliable to reflect reasonable patterns of temperature dynamics for land surface temperature in the region.展开更多
The aim of this work was to study the effect of condensed tannins （CT） on the kinetic of gas production in vitro, on the three main species of Azorean pasture： Trifolium repens, Lotus corniculatus and Lolium perenn...The aim of this work was to study the effect of condensed tannins （CT） on the kinetic of gas production in vitro, on the three main species of Azorean pasture： Trifolium repens, Lotus corniculatus and Lolium perenne, using Quebracho extract as the source of CT, and also to calculate total tannins and condensed tannins on the species studied. Lotus corniculatus, Lolium perenne and Trifolium repens were tested in vitro with the inclusion of Quebracho extract in doses of 0%, 2.5% and 5% DM. The total content in tannins was determined in the 3 species. We have found, in comparison with standard tannic acid, that tannins exist in the flower of T. repens （0.81 equivalents of tannic acid） and in L .corniculatus （1.07 equivalents of tannic acid） but not in L .perenne （0 equivalents of tannic acid）. The concentration of condensed tannins in the 3 species was： 0.34 mg/mL for T. repens; 0.83 mg/mL for L. corniculatus and 0 mg/ml for L. perenne. We verified that a significant reduction （P 〈 0.05） of gas production happened for doses of 5% of CT in comparison with the other two concentrations： 0% and 2.5% of CT. The results of this study express a reduction of the fermentation rate, which implies a reduction of gas production, so, a reduction of methane emission to the atmosphere and an increase of exploitation of the protein by ruminants.展开更多
One major feature of printing and publishing in England in the 16th and 17th centuries and repeated in subsequent centuries was that of travel tales to foreign spaces where Protestant males not only met believers in I...One major feature of printing and publishing in England in the 16th and 17th centuries and repeated in subsequent centuries was that of travel tales to foreign spaces where Protestant males not only met believers in Islam but also encountered other Europeans （mostly Catholics） in those foreign spaces. This paper will attempt to show those travellers＇ tales written by Englishmen of the early modern period as well as subsequently were not only based upon Protestant foundations but also contributed to the making of the nation.展开更多
文摘Neurenteric cysts are extremely rare congenital anomalies, often presenting in the first 5 years of life, and are caused by an incomplete separation of the notochord from the foregut during the third week of embryogenesis. They are frequently accompanied with spinal or gastrointestinal abnormalities, but the latter may be absent in adults. Although usually located in the thorax, neurenteric cysts may be found along the entire spine. We present a 24-year-old woman admitted for epigastric pain, nausea, vomiting, low grade fever and leucocytosis. She underwent cystgastrostomy for a Ioculated cyst of the distal pancreas at the age of 4 years, which recurred when she was at the age of 11 years. Ultrasound and computer tomograghy （CT） scan revealed a 16 cmx 15 cm cystic mass in the body and tail of pancreas, with a 6-7 mm thickened wall. Laboratory data and chest X-ray were normal and spinal radiographs did not show any structural abnormalities. The patient underwent a complete cyst excision, and after an uneventful recovery, remained symptom-free without recurrence during the 5-year follow-up. The cyst was found to contain 1200 mL of pale viscous fluid. It was covered by a primitive singlelayered cuboidal epithelium, along with specialized antral glandular parenchyma and hypoplastic primitive gastric mucosa. Focal glandular groups resembling those of the body of the stomach were also seen. In addition, ciliary respiratory epithelium, foci of squamous metaplasia and mucinous glands were present. The wall of the cyst contained a muscular layer, neuroglial tissue with plexogenic nerve fascicles, Paccini corpuscle-like structures, hyperplastic neuroganglionar elements and occasional psammomatous bodies, as well as fibroblast-like areas of surrounding stroma. Cartilagenous tissue was not found in any part of the cyst. Immunohistochemistry confirmed the presence of neurogenic elements marked by S-100, GFAP, NF and NSE. The gastric epithelium showed mostly CK7 and EMA immunoexpression, and the respiratory epithelium revealed a CK8 and CK18 immunoprofile without CK 10/13 positive elements, though neither CEA or AFP positive cells were found. To our knowledge, this is the first reported case of an abdominally located neurenteric cyst with no associated spinal anomalies.
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDA05110102)the National Natural Science Foundation of China (Grant No.41075062)the National Basic Research Program of China (Grant No. 2010CB951001)
文摘To improve current understanding of the water cycle,energy partitioning and CO2 exchange over hilly zone vegetative land surfaces in the subtropical monsoon environment of southern China,a long-term field experiment observatory was set up at Ningxiang,eastern Hunan Province.This paper presents a preliminary analysis of the field observations at the observatory collected from August to November 2012.Results show that significant diurnal variations in soil temperature occur only in shallow soil layers(0.05,0.10,and 0.20 m),and that heavy rainfall affects soil moisture in the deep layers(≥ 0.40 m).During the experimental period,significant diurnal variations in albedo,radiation components,energy components,and CO2 flux were observed,but little seasonal variation.Strong photosynthesis in the vegetation canopy enhanced the CO2 absorption and the latent heat released in daylight hours;Latent heat of evaporation was the main consumer of available energy in late summer.Because the field experiment data are demonstrably reliable,the observatory will provide reliable long-term measurements for future investigations of the land-atmosphere interaction over hilly land surfaces in the subtropical monsoon region of southern China.
文摘AIM: To examine the protective effect of green tea extract (GT) on hepatic fi brosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats.METHODS: HSC-T6, a rat hepatic stellate cell line, was used as an in vitro assay system. Cell proliferation, collagen content, and type 1 collagen expression were examined in activated HSC-T6 cells. Collagen was determined by estimating the hydroxyproline content. In rats with DMN-induced hepatic fi brosis, serum aspartate aminotransferase and alanine aminotransferase concentrations, liver hydroxyproline and lipid peroxides were determined. Pathologic changes were examined by hematoxylin & eosin staining.RESULTS: GT administration prevented the development of hepatic fibrosis in the rat model of DMN-induced liver fi brosis. These results were confi rmed both by liver histology and by quantitative measurement of hepatic hydroxyproline content, a marker of liver collagen deposition. Accordingly, inhibition of proliferation, reduced collagen deposition, and type 1 collagen expression were observed in activated HSC-T6 cells following GT treatment. These results imply that GT reduced the proliferation of activated HSC and down regulated the collagen content and expression of collagen type 1, thereby ameliorating hepatic fibrosis.CONCLUSION: This study demonstrates that greentea administration can effectively improve liver fibrosis caused by DMN, and may be used as a therapeutic option and preventive measure against hepatic f ibrosis.
文摘The non-linear relationships between the contents of ginsenoside Rg 1, Rb 1, Rd and Panax notoginseng saponins(PNS) in Panax notoginseng root herb and the near infrared(NIR) diffuse reflectance spectra of the herb were established by means of artificial neural networks(ANNs). Four three-layered perception feed-forward networks were trained with an error back-propagation algorithm. The significant principal components of the NIR spectral data matrix were utilized as the input of the networks. The networks architecture and parameters were selected so as to offer less prediction errors. Relative prediction errors for Rg 1, Rb 1, Rd and PNS obtained with the optimum ANN models were 8.99%, 6.54%, 8.29%, and 5.17%, respectively, which were superior to those obtained with PLSR methods. It is verified that ANN is a suitable approach to model this complex non-linearity. The developed method is fast, non-destructive and accurate and it provides a new efficient approach for determining the active components in the complex system of natural herbs.
基金supported by the National Basic Research Program of China (Grant No.2009CB723904)the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No.XDA05090201)
文摘A validation study of land surface temperature (LST) obtained from the Ka band (37 GHz) vertically polarized brightness temperature over northern China is presented.The remotely sensed LST derived jointly by the Vrije Universiteit Amsterdam and the NASA Goddard Space Flight Center (VUA-NASA) from the Advanced Microwave Scanning Radiometer-Earth Observing System (AMSR-E) were compared to the daily in-situ top soil temperature/infrared surface temperature observations from eleven/three Enhanced Coordinated Observation stations in arid and semi-arid regions of northern China.The VUA-NASA LST from the descending path exhibited a stronger correspondence to the in-situ infrared surface temperature than soil temperature observations,whereas correlations (R 2) of the latter ranged from 0.41 to 0.86.Meanwhile,the ascending overpass LST was generally warmer than the in-situ soil temperature observations at all stations,and the correlation (R 2) was between 0.07 and 0.72.Furthermore,the correlation of the descending path was generally greater than that of the ascending path at the same station.The descending path VUA-NASA LST was sensitive to precipitation and presented good agreement with ground temperature dynamics.The analyses demonstrated that the descending overpass LST was reliable to reflect reasonable patterns of temperature dynamics for land surface temperature in the region.
文摘The aim of this work was to study the effect of condensed tannins （CT） on the kinetic of gas production in vitro, on the three main species of Azorean pasture： Trifolium repens, Lotus corniculatus and Lolium perenne, using Quebracho extract as the source of CT, and also to calculate total tannins and condensed tannins on the species studied. Lotus corniculatus, Lolium perenne and Trifolium repens were tested in vitro with the inclusion of Quebracho extract in doses of 0%, 2.5% and 5% DM. The total content in tannins was determined in the 3 species. We have found, in comparison with standard tannic acid, that tannins exist in the flower of T. repens （0.81 equivalents of tannic acid） and in L .corniculatus （1.07 equivalents of tannic acid） but not in L .perenne （0 equivalents of tannic acid）. The concentration of condensed tannins in the 3 species was： 0.34 mg/mL for T. repens; 0.83 mg/mL for L. corniculatus and 0 mg/ml for L. perenne. We verified that a significant reduction （P 〈 0.05） of gas production happened for doses of 5% of CT in comparison with the other two concentrations： 0% and 2.5% of CT. The results of this study express a reduction of the fermentation rate, which implies a reduction of gas production, so, a reduction of methane emission to the atmosphere and an increase of exploitation of the protein by ruminants.
文摘One major feature of printing and publishing in England in the 16th and 17th centuries and repeated in subsequent centuries was that of travel tales to foreign spaces where Protestant males not only met believers in Islam but also encountered other Europeans （mostly Catholics） in those foreign spaces. This paper will attempt to show those travellers＇ tales written by Englishmen of the early modern period as well as subsequently were not only based upon Protestant foundations but also contributed to the making of the nation.
