Objective Bromocriptine and other dopamine D2 receptor agonists can affect a range of behaviors in nonhuman primates, particularly those behaviors associated with motor and mental function, such as suppressant behavio...Objective Bromocriptine and other dopamine D2 receptor agonists can affect a range of behaviors in nonhuman primates, particularly those behaviors associated with motor and mental function, such as suppressant behaviors and hallucinatory-like behaviors in monkeys. Besides bromocriptine, the dysfunction of the rapid eye movement sleep (REM) mechanism may also contribute to hallucinations. Dissociation of wakefulness, REM, and non-REM (NREM) can cause a series of psychotic symptoms. Methods In present study, we simultaneously recorded auditory evoked potentials (AEP) from five cerebral regions in monkeys during normal and psychotomimetic states to investigate and compare state-dependent changes in AEE Results Phase reversal of peak-to-baseline amplitude of 250 ms component (PBA250) in dorsolateral prefrontal cortex was common characteristic of hallucinatory-like and REM, and that hallucinatory-like and REM shared the equivalent modulatory orderliness of the PBA250 in dorsolateral prefrontal cortex. This result suggests that hallucinatory-like and REM share an equivalent electrophysiological modulatory in dorsolateral prefrontal cortex. Conclusion Our results reveal that emergence of the N250 in dorsolateral prefrontal cortex is an exclusive marker that may help to discern whether hallucinatory-like behaviors is exhibited, which suggests that dorsolateral prefrontal cortex may be the most pivotal region for exhibition of hallucinatory-like behaviors.展开更多
This paper deals with the applicability of human rights in general and of third-generation human right in particular. It offers an explanation of the pathetic status of human rights and suggests an alternative approac...This paper deals with the applicability of human rights in general and of third-generation human right in particular. It offers an explanation of the pathetic status of human rights and suggests an alternative approach towards "third-generation" human rights, i.e., the rights of communities. It argues that since an immanent dichotomy exists between the political aspect of human rights--the fact that their addressee is the state government--and their universal aspect, i.e., the fact that they belong to everyone and their fulfillment is demanded by international bodies, very often their possessors cannot capitalize them. Third-generation human rights encounter additional problems. Very often their respondent--the state government----cannot comply with their demands, and according to the Kantian principle "Ought Implies Can," they should be addressed towards someone who can in fact fulfill them. This article thus suggests addressing third-generation human rights towards the international community. This may exclude them from the current category of human rights, and create the need to establish a new category such as Community Rights. Such classification may bear the advantage of making these rights more applicable and accessible than they are at present.展开更多
Bazin favored every means to increase the "reality coefficient" in cinema. He specially prized cinema showing events integrally, what means, on the one hand, to show simultaneously and fully all the characters and a...Bazin favored every means to increase the "reality coefficient" in cinema. He specially prized cinema showing events integrally, what means, on the one hand, to show simultaneously and fully all the characters and all the objects pertaining to an event, and on the other to show the event integrally as it develops in time. Additionally Bazin showed that such a procedure reduces the purely literary component in cinema, and, correspondingly, increases its illusory force--as to the fictional reality presented. Yet, Bazin's work is not systematic, giving us brilliant insights scattered through many essays. Following Bazin's main idea, this presentation attempts to systematically discuss the illusory potential of the shot presenting an event integrally as compared with the imaginary, that is, literary character introduced in cinema by suggesting an event by means of montage and fragmentary shots. We proceed by means of a detailed consideration of the belief-structure of the aesthetic experience corresponding to the single shot integrally showing an event and to montage suggesting an event by means of fragmentary shots. The core of the presentation lies in defining the concept of aesthetic belief as the propositional attitude having the structure accepting that P without believing that P is the case. We will carefully distinguish that structure in the case of illusion from the case of imagination as well as from illusion as sensory-based deception.展开更多
基金supported by the grants from the Program of Chinese Acad emy of Sciences(No.KJCX1-07)National Basic Research Priorities Programme of China(No.G1999054000)+3 种基金Huo Yingdong Grant(No.91038)National Natural Science Foundation of China(No.30200068)Famous Doctors Program of Health Department of Guangdong Province(No.21)International Collaboration Key Project from the National Natural Science Foundation of China(No.30420120048).
文摘Objective Bromocriptine and other dopamine D2 receptor agonists can affect a range of behaviors in nonhuman primates, particularly those behaviors associated with motor and mental function, such as suppressant behaviors and hallucinatory-like behaviors in monkeys. Besides bromocriptine, the dysfunction of the rapid eye movement sleep (REM) mechanism may also contribute to hallucinations. Dissociation of wakefulness, REM, and non-REM (NREM) can cause a series of psychotic symptoms. Methods In present study, we simultaneously recorded auditory evoked potentials (AEP) from five cerebral regions in monkeys during normal and psychotomimetic states to investigate and compare state-dependent changes in AEE Results Phase reversal of peak-to-baseline amplitude of 250 ms component (PBA250) in dorsolateral prefrontal cortex was common characteristic of hallucinatory-like and REM, and that hallucinatory-like and REM shared the equivalent modulatory orderliness of the PBA250 in dorsolateral prefrontal cortex. This result suggests that hallucinatory-like and REM share an equivalent electrophysiological modulatory in dorsolateral prefrontal cortex. Conclusion Our results reveal that emergence of the N250 in dorsolateral prefrontal cortex is an exclusive marker that may help to discern whether hallucinatory-like behaviors is exhibited, which suggests that dorsolateral prefrontal cortex may be the most pivotal region for exhibition of hallucinatory-like behaviors.
文摘This paper deals with the applicability of human rights in general and of third-generation human right in particular. It offers an explanation of the pathetic status of human rights and suggests an alternative approach towards "third-generation" human rights, i.e., the rights of communities. It argues that since an immanent dichotomy exists between the political aspect of human rights--the fact that their addressee is the state government--and their universal aspect, i.e., the fact that they belong to everyone and their fulfillment is demanded by international bodies, very often their possessors cannot capitalize them. Third-generation human rights encounter additional problems. Very often their respondent--the state government----cannot comply with their demands, and according to the Kantian principle "Ought Implies Can," they should be addressed towards someone who can in fact fulfill them. This article thus suggests addressing third-generation human rights towards the international community. This may exclude them from the current category of human rights, and create the need to establish a new category such as Community Rights. Such classification may bear the advantage of making these rights more applicable and accessible than they are at present.
文摘Bazin favored every means to increase the "reality coefficient" in cinema. He specially prized cinema showing events integrally, what means, on the one hand, to show simultaneously and fully all the characters and all the objects pertaining to an event, and on the other to show the event integrally as it develops in time. Additionally Bazin showed that such a procedure reduces the purely literary component in cinema, and, correspondingly, increases its illusory force--as to the fictional reality presented. Yet, Bazin's work is not systematic, giving us brilliant insights scattered through many essays. Following Bazin's main idea, this presentation attempts to systematically discuss the illusory potential of the shot presenting an event integrally as compared with the imaginary, that is, literary character introduced in cinema by suggesting an event by means of montage and fragmentary shots. We proceed by means of a detailed consideration of the belief-structure of the aesthetic experience corresponding to the single shot integrally showing an event and to montage suggesting an event by means of fragmentary shots. The core of the presentation lies in defining the concept of aesthetic belief as the propositional attitude having the structure accepting that P without believing that P is the case. We will carefully distinguish that structure in the case of illusion from the case of imagination as well as from illusion as sensory-based deception.