AIM:To quantitatively assess the relationship between energy intake and the incidence of digestive cancers in a meta-analysis of cohort studies.METHODS:We searched MEDLINE,EMBASE,Science Citation Index Expanded,and th...AIM:To quantitatively assess the relationship between energy intake and the incidence of digestive cancers in a meta-analysis of cohort studies.METHODS:We searched MEDLINE,EMBASE,Science Citation Index Expanded,and the bibliographies of retrieved articles.Studies were included if they reported relative risks(RRs) and corresponding 95% CIs of digestive cancers with respect to total energy intake.When RRs were not available in the published article,they were computed from the exposure distributions.Data were extracted independently by two investigators and discrepancies were resolved by discussion with a third investigator.We performed fixed-effects meta-analyses and meta-regressions to compute the summary RR for highest versus lowest category of energy intake and for per unit energy intake and digestive cancer incidence by giving each study-specific RR a weight that was proportional to its precision.RESULTS:Nineteen studies consisting of 13 independent cohorts met the inclusion criteria.The studiesincluded 995 577 participants and 5620 incident cases of digestive cancer with an average follow-up of 11.1 years.A significant inverse association was observed between energy intake and the incidence of digestive cancers.The RR of digestive cancers for the highest compared to the lowest caloric intake category was 0.90(95% CI 0.81-0.98,P < 0.05).The RR for an increment of 239 kcal/d energy intake was 0.97(95% CI 0.95-0.99,P < 0.05) in the fixed model.In subgroup analyses,we noted that energy intake was associated with a reduced risk of colorectal cancer(RR 0.90,95% CI 0.81-0.99,P < 0.05) and an increased risk of gastric cancer(RR 1.19,95% CI 1.08-1.31,P < 0.01).There appeared to be no association with esophageal(RR 0.96,95% CI 0.86-1.07,P > 0.05) or pancreatic(RR 0.79,95% CI 0.49-1.09,P > 0.05) cancer.Associations were also similar in studies from North America and Europe.The RR was 1.02(95% CI 0.79-1.25,P > 0.05) when considering the six studies conducted in North America and 0.87(95% CI 0.77-0.98,P < 0.05) for the five studies from Europe.CONCLUSION:Our findings suggest that high energy intake may reduce the total digestive cancer incidence and has a preventive effect on colorectal cancer.展开更多
This paper considers a discrete-time queue with N-policy and LAS-DA(late arrival system with delayed access) discipline.By using renewal process theory and probability decomposition techniques,the authors derive the r...This paper considers a discrete-time queue with N-policy and LAS-DA(late arrival system with delayed access) discipline.By using renewal process theory and probability decomposition techniques,the authors derive the recursive expressions of the queue-length distributions at epochs n^-,n^+,and n.Furthermore,the authors obtain the stochastic decomposition of the queue length and the relations between the equilibrium distributions of the queue length at different epochs(n^-,n^+,n and departure epoch D_n).展开更多
In this paper we study a queueing system with state-dependent services and state-dependent vacations, or simply G/M（n）/1/K. Since the service rate is state-dependent, this system includes G/M/c and G/M/c/K queues wi...In this paper we study a queueing system with state-dependent services and state-dependent vacations, or simply G/M（n）/1/K. Since the service rate is state-dependent, this system includes G/M/c and G/M/c/K queues with various types of station vacations as special cases. We provide a recursive algorithm using the supplementary variable technique to numerically compute the stationary queue length distribution of the system. The only input requirement is the Laplace-Stieltjes transform of the interarrival distribution as well as the state-dependent service rate and state-dependent vacation rate. In a subsequent companion paper, we study its dual system M（n）/G/1/K queue with statedependent vacations.展开更多
This paper considers the Geom/G/1 queueing model with feedback according to a late arrival system with delayed access （LASDA）. Using recursive method, this paper studies the transient property of the queue size from...This paper considers the Geom/G/1 queueing model with feedback according to a late arrival system with delayed access （LASDA）. Using recursive method, this paper studies the transient property of the queue size from the initial state N（0＋） = i. Some new results about the recursive expression of the transient queue size distribution at any epoch n＋ and the recursive formulae of the equilibrium distribution are obtained. Furthermore, the recursive formulae of the equilibrium queue size distribution at epoch n-, and n are obtained, too. The important relations between stationary queue size distributions at different epochs are discovered （being different from the relations given in M/G/I queueing system）. The model discussed in this paper can be widely applied in all kinds of communications and computer network.展开更多
We study a single-server queueing system with state-dependent arrivals and general service distribution, or simply M（n）/G/1/K, where the server follows an N policy and takes multiple vacations when the system is emp...We study a single-server queueing system with state-dependent arrivals and general service distribution, or simply M（n）/G/1/K, where the server follows an N policy and takes multiple vacations when the system is empty. We provide a recursive algorithm using the supplementary variable technique to numerically compute the stationary queue length distribution of the system. The only input requirements are the Laplace-Stieltjes transforms of the service time distribution and the vacation time distribution, and the state-dependent arrival rate. The computational complexity of the algorithm is O（K^3）.展开更多
文摘AIM:To quantitatively assess the relationship between energy intake and the incidence of digestive cancers in a meta-analysis of cohort studies.METHODS:We searched MEDLINE,EMBASE,Science Citation Index Expanded,and the bibliographies of retrieved articles.Studies were included if they reported relative risks(RRs) and corresponding 95% CIs of digestive cancers with respect to total energy intake.When RRs were not available in the published article,they were computed from the exposure distributions.Data were extracted independently by two investigators and discrepancies were resolved by discussion with a third investigator.We performed fixed-effects meta-analyses and meta-regressions to compute the summary RR for highest versus lowest category of energy intake and for per unit energy intake and digestive cancer incidence by giving each study-specific RR a weight that was proportional to its precision.RESULTS:Nineteen studies consisting of 13 independent cohorts met the inclusion criteria.The studiesincluded 995 577 participants and 5620 incident cases of digestive cancer with an average follow-up of 11.1 years.A significant inverse association was observed between energy intake and the incidence of digestive cancers.The RR of digestive cancers for the highest compared to the lowest caloric intake category was 0.90(95% CI 0.81-0.98,P < 0.05).The RR for an increment of 239 kcal/d energy intake was 0.97(95% CI 0.95-0.99,P < 0.05) in the fixed model.In subgroup analyses,we noted that energy intake was associated with a reduced risk of colorectal cancer(RR 0.90,95% CI 0.81-0.99,P < 0.05) and an increased risk of gastric cancer(RR 1.19,95% CI 1.08-1.31,P < 0.01).There appeared to be no association with esophageal(RR 0.96,95% CI 0.86-1.07,P > 0.05) or pancreatic(RR 0.79,95% CI 0.49-1.09,P > 0.05) cancer.Associations were also similar in studies from North America and Europe.The RR was 1.02(95% CI 0.79-1.25,P > 0.05) when considering the six studies conducted in North America and 0.87(95% CI 0.77-0.98,P < 0.05) for the five studies from Europe.CONCLUSION:Our findings suggest that high energy intake may reduce the total digestive cancer incidence and has a preventive effect on colorectal cancer.
基金supported by the National Natural Science Foundation of China under Grant No.70871084The Specialized Research Fund for the Doctoral Program of Higher Education of China under Grant No. 200806360001a grant from the "project 211(PhaseⅢ)" of the Southwestern University of Finance and Economics, Scientific Research Fund of Southwestern University of Finance and Economics
文摘This paper considers a discrete-time queue with N-policy and LAS-DA(late arrival system with delayed access) discipline.By using renewal process theory and probability decomposition techniques,the authors derive the recursive expressions of the queue-length distributions at epochs n^-,n^+,and n.Furthermore,the authors obtain the stochastic decomposition of the queue length and the relations between the equilibrium distributions of the queue length at different epochs(n^-,n^+,n and departure epoch D_n).
基金supported by National Science Foundation under DMI-0200306supported in part by a grant from National Natural Science Foundation of China under No.70228001.
文摘In this paper we study a queueing system with state-dependent services and state-dependent vacations, or simply G/M（n）/1/K. Since the service rate is state-dependent, this system includes G/M/c and G/M/c/K queues with various types of station vacations as special cases. We provide a recursive algorithm using the supplementary variable technique to numerically compute the stationary queue length distribution of the system. The only input requirement is the Laplace-Stieltjes transform of the interarrival distribution as well as the state-dependent service rate and state-dependent vacation rate. In a subsequent companion paper, we study its dual system M（n）/G/1/K queue with statedependent vacations.
基金supported by the National Natural Science Foundation of China under Grant No. 70871084the Specialized Research Fund for the Doctoral Program of Higher Education of China under Grant No 200806360001the Scientific Research Fund of Southwestern University of Finance and Economics
文摘This paper considers the Geom/G/1 queueing model with feedback according to a late arrival system with delayed access （LASDA）. Using recursive method, this paper studies the transient property of the queue size from the initial state N（0＋） = i. Some new results about the recursive expression of the transient queue size distribution at any epoch n＋ and the recursive formulae of the equilibrium distribution are obtained. Furthermore, the recursive formulae of the equilibrium queue size distribution at epoch n-, and n are obtained, too. The important relations between stationary queue size distributions at different epochs are discovered （being different from the relations given in M/G/I queueing system）. The model discussed in this paper can be widely applied in all kinds of communications and computer network.
基金partially supported by National Science Foundation under DMI-0200306supported in part by a grant from National Natural Science Foundation of China under No.70228001.
文摘We study a single-server queueing system with state-dependent arrivals and general service distribution, or simply M（n）/G/1/K, where the server follows an N policy and takes multiple vacations when the system is empty. We provide a recursive algorithm using the supplementary variable technique to numerically compute the stationary queue length distribution of the system. The only input requirements are the Laplace-Stieltjes transforms of the service time distribution and the vacation time distribution, and the state-dependent arrival rate. The computational complexity of the algorithm is O（K^3）.
