Peeling trunk,binding insect-attracting belt,cleaning orchard and soil-covering under the crown were the control methods on overwintering generation of oriental fruit moth.However,they had not been applied widely on t...Peeling trunk,binding insect-attracting belt,cleaning orchard and soil-covering under the crown were the control methods on overwintering generation of oriental fruit moth.However,they had not been applied widely on the production because of the lack of systematic quantitative evaluation.Aiming at this fact,the control effects of these technical measures were studied in peach with different ripening period.The results showed that peeling trunk was the best with the control effect of88.64%.The control effect of binding insect-attracting belt of grass bundle was74.13%,which was the most economical and efficient.Covering with soil layer of 3cm under the crown during the middle ten days of March could holdback the adult getting out from soil.Cleaning deadwood could clean out the overwintering larvae on the ground.展开更多
The subcutaneous implantable cardioverter defibrillators (SICD) is an altemative to the transvenous ICD for the prevention of sudden cardiac death (SCD). Multiple studies have shown that the SICD is safe and effec...The subcutaneous implantable cardioverter defibrillators (SICD) is an altemative to the transvenous ICD for the prevention of sudden cardiac death (SCD). Multiple studies have shown that the SICD is safe and effective in treating ventricular arrhythmias. While earlier stud- ies mainly enrolled younger patients with channelopathies, more recent reports included patients with "typical" indications for ICD therapy for the prevention of SCD. In this review we summarize the data available to date on the SICD while highlighting its pros and cons.展开更多
The relative potentials of either heartwood extracts (air dry extracts in 60 percent methanol) of very durable woods (Afzelia africana J.E. Smith; Erythrophleum suaveolens (Guill & Perr.) Brenam. Syn. E guinensis ...The relative potentials of either heartwood extracts (air dry extracts in 60 percent methanol) of very durable woods (Afzelia africana J.E. Smith; Erythrophleum suaveolens (Guill & Perr.) Brenam. Syn. E guinensis G.Don. or Milicia excelsa (Welw) C.C. Berg. Syn. Chlorophora excelsa (Welw) Benth.) or any of two proprietary wood preservatives (AWPA type 揅? Chromated Copper Arsenate (CCA) or 5 percent solution of AWPA Standard Designation P ??type 揅? Pentanchlorophenol (Penta) in light oil solvent) to suppress attack on pressure treated Antiaris toxicaria Lesch Sapwood by either any of three species of decaying fungi (Coridopsis Polyzona Klotzch; Lenzites trabea; or Trametes cingulata Fr.) under soil block exposure conditions were investigated and threshold values determined. Extract/preservative dosages were either 8.009; 24.778; 48.056; 96.111 or 144.167 kg穖-3 (0.5; 1.5; 3.0; 6.0 or 9.0 1b/ft3). Exposure was for either 14 or 28 weeks and in accordance with ASTM D1413 72 Provisions. Conclusions reached were that at threshold values the ability of either any of the heartwood extracts or proprietary wood preservatives to suppress attack under conditions in this study was significant at 0.01. Relative efficacy of those biocides was dependent on fungal species. Neither any of the heartwood extracts nor any of the proprietary wood preservatives (except in the case of Trametes cingulata attack on CCA treated wood at highest retention level) was able to confer 搗ery durable?rating on treated wood. Possible reasons for the reduced relative durability of extracts visa vis native heartwood were advanced. At the highest retention level (144.167 kg穖-3) there was no significant difference (at 0.05 level) between efficacy of each of the heartwood extracts and any of the proprietary wood preservatives (CCA or Penta).展开更多
Objective:To observe psychological changes of the armed policemen under stress state and the effect of acupuncture intervention for exploring possible measures in raising the armed policemen's capability in dealin...Objective:To observe psychological changes of the armed policemen under stress state and the effect of acupuncture intervention for exploring possible measures in raising the armed policemen's capability in dealing with the suddenly-occurred accidents. Methods: In the first part of the study for observing psychological changes, a total of 90 volunteer armed policemen participating in anti-terrorism maneuver were randomly and evenly divided into anti-chemical weapon group, flight reconnaissance group and hostage-rescuing group. 30 logistic personals were selected to form control group. Symptom Checklist-90 (SCL-90) questionnaire was used to assess the psychological state of these anti-terrorism policemen. In the second part of the study for observing the effect of acupuncture, 60 policemen with anxiety and depression who were determined by Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) were randomly and evenly divided into non-acupuncture and acupuncture groups, and other 30 policemen with normal psychological state were selected to form control group. Two weeks before anti-terrorism maneuver, participants of acupuncture group were asked to receive continuous acupuncture treatment of bilateral Neiguan (内关 PC 6) and Zusanli (足三里 ST 36), once daily, 15 min every time. Results:Comparison among the first 4 groups displayed that the total scores, scores of body feeling reactions, interpersonal relation, depression, anxiety, terror, and psychological problems of flight reconnaissance and hostage-rescuing groups were significantly higher than those of control group (P<0.05-0.01), suggesting that the psychological stress pressure was strongest in flight reconnaissance policemen and secondary in hostage-rescuing policemen, followed by anti-chemical weapon policemen. Following administration of acupuncture intervention, scores of both SDS and SAS in acupuncture group were considerably lower than those of non-acupuncture group (P< 0.01), showing that acupuncture intervention could reduce psychological stress reactions in the armed policemen undergoing anti-terrorism exercise. Conclusion: Before anti-terrorism exercise,neerly all the armed policemen have different degrees of psychological problems, while acupuncture intervention can improve their psychological state.展开更多
AIM: Cardiotonic Pill (CP), an oral herbal medicine that includes Danshen (Salviae Miltiorrhizae), Panax notoginseny and Dyroblanops aromatica gaettn, has been clinically used for vascular diseases such as occlusive v...AIM: Cardiotonic Pill (CP), an oral herbal medicine that includes Danshen (Salviae Miltiorrhizae), Panax notoginseny and Dyroblanops aromatica gaettn, has been clinically used for vascular diseases such as occlusive vasculitis, coronary diseases, atherosclerosis, and cerebral infarction. The main component, Salviae Miltiorrhizae, has been reported to prevent cerebral and intestinal reperfusion injury. However, little is known about the effect of CP on hepatic microcirculation. Thus, this study aimed to determine whether CP could affect hepatic microvascular dysfunction elicited by gut ischemia/ reperfusion (I/R) in rats fed ethanol chronically. METHODS: Male Wistar rats were pair-fed with a liquid diet containing ethanol or isocaloric control diet for 6 wk. After laparotomy, one lobe of the liver was examined through an inverted intravital microscope. The rats were exposed to 30 min of gut ischemia followed by 60 min of reperfusion. Rhodamine-6G-labeled leukocytes in the sinusoids were observed 90 min after the onset of superior mesenteric artery occlusion. Plasma tumor necrosis factor (TNF)-α and endotoxin levels were measured 1 h after the onset of reperfusion. Plasma alanine aminotransferase (ALT) activities were measured 6 h after the onset of reperfusion. In another set of experiments, CP (0.8 g/kg, intragastrically) was administered 1 and 24 h before the onset of ischemia. RESULTS: In control rats, gut I/R elicited increases in the number of stationary leukocytes, and plasma TNF-α and endotoxin levels and plasma ALT activities. These changes were mitigated by pretreatment with CP. In ethanol-fed rats, the gut I/R-induced increases in the number of stationary leukocytes, plasma endotoxin levels and ALT activities were enhanced. Pretreatment with CP attenuated the enhancement of gut I/R-induced responses by chronic ethanol consumption. CONCLUSION: These results suggest that CP prevents the gut I/R-induced hepatic microvascular dysfunction and hepatocellular injury. A reduction of inflammatory responses such as TNF-α production via reduction of blood endotoxin levels appears to be involved in the mechanisms. Chronic ethanol consumption enhances gut I/R-induced hepatic microvascular and hepatocellular injury. CP also attenuates an enhancement of gut I/R-induced responses by chronic ethanol consumption via the reduction of blood endotoxin levels.展开更多
AIM: To study the hemodynamic effects of spironolactone with propranolol vs propranolol alone in the secondary prophylaxis of variceal bleeding. METHODS: Thirty-five cirrhotics with variceal bleeding randomly received...AIM: To study the hemodynamic effects of spironolactone with propranolol vs propranolol alone in the secondary prophylaxis of variceal bleeding. METHODS: Thirty-five cirrhotics with variceal bleeding randomly received propranolol (n = 17: Group A) or spironolactone plus propranolol (n = 18: Group B). Hemodynamic assessment was performed at baseline and on the eighth day. RESULTS: Spironolactone with propranolol caused a greater reduction in the hepatic venous pressure gradient than propranolol alone (26.94% vs 10.2%; P < 0.01). Fourteen out of eighteen patients on the combination treatment had a reduction in hepatic venous pressure gradient to ≤ 12 mmHg or a 20% reduction from baseline in contrast to only six out of seventeen (6/17) on propranolol alone (P < 0.05). CONCLUSION: Spironolactone with propranolol results in a better response with a greater reduction in hepatic venous pressure gradient in the secondary prophylaxis of variceal bleeding. A greater number of patients may be protected by this combination therapy than by propranolol alone. Hence, this combination may be recommended for secondary prophylaxis in patients with variceal bleeding.展开更多
High-density lipoproteins (HDLs) have been well established to protect against the development of atherosclerotic cardiovascular disease. It has become apparent that in addition to the promotion of reverse cholester...High-density lipoproteins (HDLs) have been well established to protect against the development of atherosclerotic cardiovascular disease. It has become apparent that in addition to the promotion of reverse cholesterol transport, HDLs possess a number of additional functional properties that may contribute to their beneficial influence on the arterial wall. A number of exciting therapeutic strategies have been developed that target HDL and its ability to protect against the development of atherosclerotic plaque. This paper will review how the promotion of the functional properties of HDL inhibits the formation of atherosclerotic plaque and stabilises lesions in patients with established disease.展开更多
1 BackgroundIn the United States, life expectancy is rising, particularly among the older population (〉 65 years), with projected estimates approaching 20% by year 2050. Despite improved survival estimates, cardiov...1 BackgroundIn the United States, life expectancy is rising, particularly among the older population (〉 65 years), with projected estimates approaching 20% by year 2050. Despite improved survival estimates, cardiovascular diseases remain the leading cause of morbidity and mortality resulting in substantial increase in health care cost. For younger adults, the evidence for secondary cardiovascular prevention is well established and corroborated by robust data. However, the application of risk reduction strategies in older populations remains an area of active debate. Many assume that vulnerability to chronic cardiovascular diseases is an inexorable part of aging such that the risks attributable to prevention outweigh potential benefits.展开更多
Most transactional memory (TM) research focused on multi-core processors, and others investigated at the clusters, leaving the area of non-uniform memory access (NUMA) system unexplored. The existing TM implementation...Most transactional memory (TM) research focused on multi-core processors, and others investigated at the clusters, leaving the area of non-uniform memory access (NUMA) system unexplored. The existing TM implementations made significant performance degradation on NUMA system because they ignored the slower remote memory access. To solve this problem, a latency-based conflict detection and a forecasting-based conflict prevention method were proposed. Using these techniques, the NUMA aware TM system was presented. By reducing the remote memory access and the abort rate of transaction, the experiment results show that the NUMA aware strategies present good practical TM performance on NUMA system.展开更多
AIM:To evaluate pretreatment serum carcinoembryonic antigen(CEA) as a predictor of survival for patients with locally advanced gastric cancer receiving perioperative chemotherapy.METHODS:We retrospectively studied a c...AIM:To evaluate pretreatment serum carcinoembryonic antigen(CEA) as a predictor of survival for patients with locally advanced gastric cancer receiving perioperative chemotherapy.METHODS:We retrospectively studied a cohort of 228 gastric cancer patients who underwent D2 gastrectomy combined with chemotherapy at the Sun Yat-sen University Cancer Center between January 2005 and December 2009.Among them,168 patients received 6-12 cycles of oxaliplatin-based adjuvant(post-operative) chemotherapy,while 60 received perioperative chemotherapy(2 cycles of FOLFOX6 or XELOX before surgery and 4-10 cycles after surgery).Serum CEA was measured using an enzyme immunoassay.The followup lasted until December 2010.RESULTS:In the group that had elevated serum CEA,the difference in survival time between patients receiving perioperative chemotherapy and those receiving adjuvant chemotherapy had no statistical significance(P > 0.05).However,in the group that had normal serum CEA,patients receiving perioperative chemotherapy had a longer survival time.In multivariate analysis,T staging and lymph node metastatic rate were independent prognostic factors for the patients.Perioperative chemotherapy improved the overall survival of patients who had a normal pretreatment CEA level(P = 0.070).CONCLUSION:Normal pretreatment serum CEA is a predictor of survival for patients receiving perioperative chemotherapy.展开更多
AIM: The use of low-dose aspirin to prevent cardiovascular disease events is well established. However, the incidence and predictors of upper gastrointestinal bleeding (UGIB) with its use are unknown. We studied pr...AIM: The use of low-dose aspirin to prevent cardiovascular disease events is well established. However, the incidence and predictors of upper gastrointestinal bleeding (UGIB) with its use are unknown. We studied prospectively the incidence and outcome of peptic ulceration in low-dose aspirin users. METHODS: A total of 991 patients with coronary artery disease (CAD) on low-dose aspirin were prospectively followed-up for two years for the occurrence and clinical features of first hospitalized episode of UGIB. RESULTS: UGIB had a bimodal presentation with 45% occurring within four months of aspirin initiation and had an overall prevalence of 1.5% per year. There was no UGIB-related death. Hypertension (OR = 4.6, 95%CI 1.5 - 14.7, P = 0.009), history of peptic ulceration (OR = 3.1, 95%CI 1.1 - 9.0, P = 0.039), tertiary education (OR = 3.08, 95%CI 1.1 - 9.0, P = 0.039) and higher lean body mass (P = 0.016) were independent factors associated with UGIB. Use of nitrate did not reduce UGIB. CONCLUSION: The incidence of UGIB in patients with CAD on long-term low-dose aspirin is low, but is accompanied with significant morbidity. With prolonged use of aspirin, UGIB continues to be a problem for those with risk factors and especially in patients with a history of peptic ulcers, in which UGIB tends to occur early after aspirin therapy.展开更多
Objectives:This study aims to determine if patients with acute myocardial infarction differ in illness perception and secondary prevention outcomes depending on the treatment they received.Methods:A repeated measures ...Objectives:This study aims to determine if patients with acute myocardial infarction differ in illness perception and secondary prevention outcomes depending on the treatment they received.Methods:A repeated measures design was used to compare patients with acute myocardial infarction receiving three different treatment modalities:ST-elevation myocardial infarction treated by primary percutaneous coronary intervention,ST-elevation myocardial infarction treated by thrombolytic therapy,and non ST-elevation myocardial infarction treated by medication.A convenient sampling technique was used to recruit 206 patients with acute myocardial infarction who agreed to participate in the current study.Patients'illness perception,physical activity,and demographical and clinical data were collected during hospital admission and again at 6 months.Results:A total of 186 patients completed the study.Results showed that the primary percutaneous coronary intervention group perceived their illness as acute rather than chronic(P=0.034)and has lower personal control(P=0.032),higher treatment control(P=0.025),and higher perception of illness coherence(P=0.022)compared with patients receiving thrombolytic therapy and treated after non-ST segment infarction.Moreover,they report low control of their blood pressure(P=0.013)and less physical activity(P=0.001).Conclusion:The results of this study revealed that patients'treated with primary percutaneous coronary intervention had negative illness perception and limited behavioral changes 6 months after hospitalization in comparison with other treatment modalities such as percutaneous coronary intervention and thrombolytic treatment.Further research is recommended to confirm this association with longer follow-up study and among different cultures.展开更多
Background Influenza vaccination has been clinically shown to reduce adverse cardiovascular outcomes in acute coronary syndrome (ACS) patients, but the economic perspectives can provide important data to make inform...Background Influenza vaccination has been clinically shown to reduce adverse cardiovascular outcomes in acute coronary syndrome (ACS) patients, but the economic perspectives can provide important data to make informed decisions. This study aimed to perform the economic evaluation of lifelong annual influenza vaccination for cardiovascular events and well-established pneumonia prevention. Methods Lifetime costs, life-expectancy, and quality-adjusted live years (QALYs) were estimated beyond one-year cycle length of a six-health states Markov model condition on whether a hospitalization for ACS, stroke, heart failure, pneumonia, no hospitalizations occurred, or death. The comparison of three age-groups of 40-49, 50-65, and 〉 65 years scenario was performed. Incremental cost-effectiveness ratio (ICER) and net monetary benefit (NMB) were presented as a societal perspective in 2016. The model robustness was determined by one-way and prob- abilistic sensitivity analyses. Results The influenza vaccination was cost-effective in all age-groups, by dominant ICERs (lower cost with higher effectiveness) which was completely lower than acceptable willingness-to-pay threshold of Thailand [160,000 THB (4,466.8 USD) per QALYs], with a great incremental value of NMB. Especially, the 50-year-old-and- above scenario was shown as the most benefit at 129,092 THB (3,603.9 USD) for each patient. Conclusions The annually additional influenza vaccination to standard treatment in ACS was cost-effective in all age-groups, which should be considered in clinical practice and health-policy making process.展开更多
The breeding and communication of cult are all realized on the base of psychological activities, psychological factors play an important role in preventing and resisting breeding and communication of cult, and in this...The breeding and communication of cult are all realized on the base of psychological activities, psychological factors play an important role in preventing and resisting breeding and communication of cult, and in this paper, it demonstrates respectively at this point, and starts from forming the long-term mechanism of the Chinese cult governance and proposes the conception and specific suggestions accordingly of establishing the national psychological assistance system to prevent and resist breeding and communication of cult展开更多
This paper attempts to analyze Blanche's psyche in relation to her employing defense mechanism to restore her mental health and herself in A Streetcar Named Desire (1947) by the American playwright Tennessee Willia...This paper attempts to analyze Blanche's psyche in relation to her employing defense mechanism to restore her mental health and herself in A Streetcar Named Desire (1947) by the American playwright Tennessee Williams. It focuses on her replacing reality with fantastic embodiments or illusion. She has taken unacceptable impulses into acceptable forms by unconsciously blocking the impulses such as superego and thereby reducing agony for the earlier traumatic experiences left indelible marks on her mind, and anxiety for survival. Her anxiety becomes too overwhelming that her ego urgently employs defense mechanisms to protect her. With her new hopes and dreams she desires to replace the highly stressful loss. Under mental and social stress, her illusion and her falsification of reality nevertheless became unable to overcome recurring trauma-causing situation in reality and her healing process thereby leaving her on the verge of extinction.展开更多
Shopping malls are accessed by people from all walks of life and, therefore, provision of adequate fire safety measures is equally important. In Dares Salaam, Tanzania, at large construction, use of shopping malls is ...Shopping malls are accessed by people from all walks of life and, therefore, provision of adequate fire safety measures is equally important. In Dares Salaam, Tanzania, at large construction, use of shopping malls is a relatively new experience, and risks associated with use of shopping malls, such as fire outbreak, are not evident to frequent users. The main purpose of the study is to assess awareness of fire safety measures for users and staff of two shopping malls located in Dares Salaam. The research adopted a case study strategy, and 100 respondents were involved in the study. Both random and purposive sampling methods were used to select respondents for the study. Multiple sources of evidence were used in data collection, namely literature review, observations, questionnaires and interviews. Findings indicate that both shopping malls have in place fairly fire prevention measures with varying degrees. Majority of staff and users indicated that they know fire safety measures but their poor knowledge was reflected in assessing them on diferent equipment and installations, such as foam, hose reel, sprinklers and drenchers. The paper concludes that awarenes of fire safety measure of users and staff of the two shopping malls is relatively low. It is, therefore, recommended that provision of fire safety training and instructions, such as posters for users and seminars for staff of shopping malls, shall be a main focus of shopping malls owners and responsible authorities.展开更多
The World Health Organization (WHO) standard assay for determining antibody level is the rapid fluorescent focus inhibition test (RFFIT) and is used to determine the degree of immunity after vaccination against ra...The World Health Organization (WHO) standard assay for determining antibody level is the rapid fluorescent focus inhibition test (RFFIT) and is used to determine the degree of immunity after vaccination against rabies. To compare the difference in RFFIT results between the laboratories of The National Institute of Infectious Disease in Japan (NIID) and the Chinese Centre for Disease Control (CCDC) as well the influence of the choice of standard serum (STD) for the detection, the two laboratories detection methods were simultaneously manipulated by RFFIT. The reference serums used in NIID and the WHO standard serum used in CCDC were compared in the same RFFIT detection to determine the titer of four sera samples C1, Sl, S2 and S4 in parallel, and the titers of the detected sera samples were calculated using the standard formula for neutralizing antibody titer. No significant difference was found in RFFIT methods from the two laboratories and the RFFIT testing procedures of the two laboratories have good consistency. However, different titers were obtained with the tentative internal standard serum (TI-STD) produced by adjusting to 2.0 IU of WHO standard serum in NIID and the WHO STD. The titer determined with the TI-STD was higher than that determined with WHO STD, This difference appears to be significant and requires further investigation展开更多
The joint of clay core-wall and concrete cut-off wall is one of the weakest parts in high earth and rockftll dams.A kind of highly plastic clay is always fixed on the joint to fit the large shear deformation between c...The joint of clay core-wall and concrete cut-off wall is one of the weakest parts in high earth and rockftll dams.A kind of highly plastic clay is always fixed on the joint to fit the large shear deformation between clay core-wall and concrete cut-offwall,so the hydro-mechanical coupling mechanisms on the joint under high stress,high hydraulic gradient,and large shear deformation are of great importance for the evaluation of dam safety.The hydro-mechanical coupling characteristics of the joint of the highly plastic clay and the concrete cut-off wall in a high earth and rockfill dam in China were studied by using a newly designed soil-structure contact erosion apparatus.The experimental results indicate that:1) Shear failure on the joint is due to the hydro-mechanical coupling effect of stress and seepage failure.The seepage failure will induce the final shear failure when the ratio of deviatoric stress to confining pressure is within 1.0-1.2; 2) A negative exponential permeability empirical model for the joint denoted by a newly defined principal stress function,which considers the coupling effect of confining pressure and axial pressure on the permeability,is established based on hydro-mechanical coupling experiments.3) The variation of the settlement before and after seepage failure is very different.The settlement before seepage failure changes very slowly,while it increases significantly after the seepage failure.4) The stress-strain relationship is of a strain softening type.5) Flow along the joint still follows Darcian flow rule.The results will provide an important theoretical basis for the further evaluation on the safety of the high earth and rockfill dam.展开更多
Two-dimensional physical models of low crested breakwaters were tested to establish the effect of water depth, crest width, slope, stone size, core permeability and incident wave characteristics on the wave transforma...Two-dimensional physical models of low crested breakwaters were tested to establish the effect of water depth, crest width, slope, stone size, core permeability and incident wave characteristics on the wave transformation processes. The structure of the breakwaters can be used as coastal protection system by reducing the amount of incoming wave energy. Effect of slope, core permeability, water depth and incident wave characteristics on the stability was also studied. The breakwater model consisted of a core and two armour layers attacked by irregular waves. This paper discusses and compares the test results with the existing design equations. In general, the existing design equations do not seem to predict the wave transmission and reflection accurately for the range of test data. In the range of variable tested, it was observed that the water depth, crest width and wave period have a significant influence on wave transmission process. Further, results show strong influence of the water depth and wave period on the wave reflection process. The structural stability of low crested breakwaters is very much affected by the water depth and wave period.展开更多
文摘Peeling trunk,binding insect-attracting belt,cleaning orchard and soil-covering under the crown were the control methods on overwintering generation of oriental fruit moth.However,they had not been applied widely on the production because of the lack of systematic quantitative evaluation.Aiming at this fact,the control effects of these technical measures were studied in peach with different ripening period.The results showed that peeling trunk was the best with the control effect of88.64%.The control effect of binding insect-attracting belt of grass bundle was74.13%,which was the most economical and efficient.Covering with soil layer of 3cm under the crown during the middle ten days of March could holdback the adult getting out from soil.Cleaning deadwood could clean out the overwintering larvae on the ground.
文摘The subcutaneous implantable cardioverter defibrillators (SICD) is an altemative to the transvenous ICD for the prevention of sudden cardiac death (SCD). Multiple studies have shown that the SICD is safe and effective in treating ventricular arrhythmias. While earlier stud- ies mainly enrolled younger patients with channelopathies, more recent reports included patients with "typical" indications for ICD therapy for the prevention of SCD. In this review we summarize the data available to date on the SICD while highlighting its pros and cons.
文摘The relative potentials of either heartwood extracts (air dry extracts in 60 percent methanol) of very durable woods (Afzelia africana J.E. Smith; Erythrophleum suaveolens (Guill & Perr.) Brenam. Syn. E guinensis G.Don. or Milicia excelsa (Welw) C.C. Berg. Syn. Chlorophora excelsa (Welw) Benth.) or any of two proprietary wood preservatives (AWPA type 揅? Chromated Copper Arsenate (CCA) or 5 percent solution of AWPA Standard Designation P ??type 揅? Pentanchlorophenol (Penta) in light oil solvent) to suppress attack on pressure treated Antiaris toxicaria Lesch Sapwood by either any of three species of decaying fungi (Coridopsis Polyzona Klotzch; Lenzites trabea; or Trametes cingulata Fr.) under soil block exposure conditions were investigated and threshold values determined. Extract/preservative dosages were either 8.009; 24.778; 48.056; 96.111 or 144.167 kg穖-3 (0.5; 1.5; 3.0; 6.0 or 9.0 1b/ft3). Exposure was for either 14 or 28 weeks and in accordance with ASTM D1413 72 Provisions. Conclusions reached were that at threshold values the ability of either any of the heartwood extracts or proprietary wood preservatives to suppress attack under conditions in this study was significant at 0.01. Relative efficacy of those biocides was dependent on fungal species. Neither any of the heartwood extracts nor any of the proprietary wood preservatives (except in the case of Trametes cingulata attack on CCA treated wood at highest retention level) was able to confer 搗ery durable?rating on treated wood. Possible reasons for the reduced relative durability of extracts visa vis native heartwood were advanced. At the highest retention level (144.167 kg穖-3) there was no significant difference (at 0.05 level) between efficacy of each of the heartwood extracts and any of the proprietary wood preservatives (CCA or Penta).
文摘Objective:To observe psychological changes of the armed policemen under stress state and the effect of acupuncture intervention for exploring possible measures in raising the armed policemen's capability in dealing with the suddenly-occurred accidents. Methods: In the first part of the study for observing psychological changes, a total of 90 volunteer armed policemen participating in anti-terrorism maneuver were randomly and evenly divided into anti-chemical weapon group, flight reconnaissance group and hostage-rescuing group. 30 logistic personals were selected to form control group. Symptom Checklist-90 (SCL-90) questionnaire was used to assess the psychological state of these anti-terrorism policemen. In the second part of the study for observing the effect of acupuncture, 60 policemen with anxiety and depression who were determined by Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) were randomly and evenly divided into non-acupuncture and acupuncture groups, and other 30 policemen with normal psychological state were selected to form control group. Two weeks before anti-terrorism maneuver, participants of acupuncture group were asked to receive continuous acupuncture treatment of bilateral Neiguan (内关 PC 6) and Zusanli (足三里 ST 36), once daily, 15 min every time. Results:Comparison among the first 4 groups displayed that the total scores, scores of body feeling reactions, interpersonal relation, depression, anxiety, terror, and psychological problems of flight reconnaissance and hostage-rescuing groups were significantly higher than those of control group (P<0.05-0.01), suggesting that the psychological stress pressure was strongest in flight reconnaissance policemen and secondary in hostage-rescuing policemen, followed by anti-chemical weapon policemen. Following administration of acupuncture intervention, scores of both SDS and SAS in acupuncture group were considerably lower than those of non-acupuncture group (P< 0.01), showing that acupuncture intervention could reduce psychological stress reactions in the armed policemen undergoing anti-terrorism exercise. Conclusion: Before anti-terrorism exercise,neerly all the armed policemen have different degrees of psychological problems, while acupuncture intervention can improve their psychological state.
文摘AIM: Cardiotonic Pill (CP), an oral herbal medicine that includes Danshen (Salviae Miltiorrhizae), Panax notoginseny and Dyroblanops aromatica gaettn, has been clinically used for vascular diseases such as occlusive vasculitis, coronary diseases, atherosclerosis, and cerebral infarction. The main component, Salviae Miltiorrhizae, has been reported to prevent cerebral and intestinal reperfusion injury. However, little is known about the effect of CP on hepatic microcirculation. Thus, this study aimed to determine whether CP could affect hepatic microvascular dysfunction elicited by gut ischemia/ reperfusion (I/R) in rats fed ethanol chronically. METHODS: Male Wistar rats were pair-fed with a liquid diet containing ethanol or isocaloric control diet for 6 wk. After laparotomy, one lobe of the liver was examined through an inverted intravital microscope. The rats were exposed to 30 min of gut ischemia followed by 60 min of reperfusion. Rhodamine-6G-labeled leukocytes in the sinusoids were observed 90 min after the onset of superior mesenteric artery occlusion. Plasma tumor necrosis factor (TNF)-α and endotoxin levels were measured 1 h after the onset of reperfusion. Plasma alanine aminotransferase (ALT) activities were measured 6 h after the onset of reperfusion. In another set of experiments, CP (0.8 g/kg, intragastrically) was administered 1 and 24 h before the onset of ischemia. RESULTS: In control rats, gut I/R elicited increases in the number of stationary leukocytes, and plasma TNF-α and endotoxin levels and plasma ALT activities. These changes were mitigated by pretreatment with CP. In ethanol-fed rats, the gut I/R-induced increases in the number of stationary leukocytes, plasma endotoxin levels and ALT activities were enhanced. Pretreatment with CP attenuated the enhancement of gut I/R-induced responses by chronic ethanol consumption. CONCLUSION: These results suggest that CP prevents the gut I/R-induced hepatic microvascular dysfunction and hepatocellular injury. A reduction of inflammatory responses such as TNF-α production via reduction of blood endotoxin levels appears to be involved in the mechanisms. Chronic ethanol consumption enhances gut I/R-induced hepatic microvascular and hepatocellular injury. CP also attenuates an enhancement of gut I/R-induced responses by chronic ethanol consumption via the reduction of blood endotoxin levels.
文摘AIM: To study the hemodynamic effects of spironolactone with propranolol vs propranolol alone in the secondary prophylaxis of variceal bleeding. METHODS: Thirty-five cirrhotics with variceal bleeding randomly received propranolol (n = 17: Group A) or spironolactone plus propranolol (n = 18: Group B). Hemodynamic assessment was performed at baseline and on the eighth day. RESULTS: Spironolactone with propranolol caused a greater reduction in the hepatic venous pressure gradient than propranolol alone (26.94% vs 10.2%; P < 0.01). Fourteen out of eighteen patients on the combination treatment had a reduction in hepatic venous pressure gradient to ≤ 12 mmHg or a 20% reduction from baseline in contrast to only six out of seventeen (6/17) on propranolol alone (P < 0.05). CONCLUSION: Spironolactone with propranolol results in a better response with a greater reduction in hepatic venous pressure gradient in the secondary prophylaxis of variceal bleeding. A greater number of patients may be protected by this combination therapy than by propranolol alone. Hence, this combination may be recommended for secondary prophylaxis in patients with variceal bleeding.
文摘High-density lipoproteins (HDLs) have been well established to protect against the development of atherosclerotic cardiovascular disease. It has become apparent that in addition to the promotion of reverse cholesterol transport, HDLs possess a number of additional functional properties that may contribute to their beneficial influence on the arterial wall. A number of exciting therapeutic strategies have been developed that target HDL and its ability to protect against the development of atherosclerotic plaque. This paper will review how the promotion of the functional properties of HDL inhibits the formation of atherosclerotic plaque and stabilises lesions in patients with established disease.
文摘1 BackgroundIn the United States, life expectancy is rising, particularly among the older population (〉 65 years), with projected estimates approaching 20% by year 2050. Despite improved survival estimates, cardiovascular diseases remain the leading cause of morbidity and mortality resulting in substantial increase in health care cost. For younger adults, the evidence for secondary cardiovascular prevention is well established and corroborated by robust data. However, the application of risk reduction strategies in older populations remains an area of active debate. Many assume that vulnerability to chronic cardiovascular diseases is an inexorable part of aging such that the risks attributable to prevention outweigh potential benefits.
基金Projects(61003075, 61170261) supported by the National Natural Science Foundation of China
文摘Most transactional memory (TM) research focused on multi-core processors, and others investigated at the clusters, leaving the area of non-uniform memory access (NUMA) system unexplored. The existing TM implementations made significant performance degradation on NUMA system because they ignored the slower remote memory access. To solve this problem, a latency-based conflict detection and a forecasting-based conflict prevention method were proposed. Using these techniques, the NUMA aware TM system was presented. By reducing the remote memory access and the abort rate of transaction, the experiment results show that the NUMA aware strategies present good practical TM performance on NUMA system.
基金Supported by Grant from the State Key Program of the National Natural Science Foundation of China,No. 81030043
文摘AIM:To evaluate pretreatment serum carcinoembryonic antigen(CEA) as a predictor of survival for patients with locally advanced gastric cancer receiving perioperative chemotherapy.METHODS:We retrospectively studied a cohort of 228 gastric cancer patients who underwent D2 gastrectomy combined with chemotherapy at the Sun Yat-sen University Cancer Center between January 2005 and December 2009.Among them,168 patients received 6-12 cycles of oxaliplatin-based adjuvant(post-operative) chemotherapy,while 60 received perioperative chemotherapy(2 cycles of FOLFOX6 or XELOX before surgery and 4-10 cycles after surgery).Serum CEA was measured using an enzyme immunoassay.The followup lasted until December 2010.RESULTS:In the group that had elevated serum CEA,the difference in survival time between patients receiving perioperative chemotherapy and those receiving adjuvant chemotherapy had no statistical significance(P > 0.05).However,in the group that had normal serum CEA,patients receiving perioperative chemotherapy had a longer survival time.In multivariate analysis,T staging and lymph node metastatic rate were independent prognostic factors for the patients.Perioperative chemotherapy improved the overall survival of patients who had a normal pretreatment CEA level(P = 0.070).CONCLUSION:Normal pretreatment serum CEA is a predictor of survival for patients receiving perioperative chemotherapy.
文摘AIM: The use of low-dose aspirin to prevent cardiovascular disease events is well established. However, the incidence and predictors of upper gastrointestinal bleeding (UGIB) with its use are unknown. We studied prospectively the incidence and outcome of peptic ulceration in low-dose aspirin users. METHODS: A total of 991 patients with coronary artery disease (CAD) on low-dose aspirin were prospectively followed-up for two years for the occurrence and clinical features of first hospitalized episode of UGIB. RESULTS: UGIB had a bimodal presentation with 45% occurring within four months of aspirin initiation and had an overall prevalence of 1.5% per year. There was no UGIB-related death. Hypertension (OR = 4.6, 95%CI 1.5 - 14.7, P = 0.009), history of peptic ulceration (OR = 3.1, 95%CI 1.1 - 9.0, P = 0.039), tertiary education (OR = 3.08, 95%CI 1.1 - 9.0, P = 0.039) and higher lean body mass (P = 0.016) were independent factors associated with UGIB. Use of nitrate did not reduce UGIB. CONCLUSION: The incidence of UGIB in patients with CAD on long-term low-dose aspirin is low, but is accompanied with significant morbidity. With prolonged use of aspirin, UGIB continues to be a problem for those with risk factors and especially in patients with a history of peptic ulcers, in which UGIB tends to occur early after aspirin therapy.
文摘Objectives:This study aims to determine if patients with acute myocardial infarction differ in illness perception and secondary prevention outcomes depending on the treatment they received.Methods:A repeated measures design was used to compare patients with acute myocardial infarction receiving three different treatment modalities:ST-elevation myocardial infarction treated by primary percutaneous coronary intervention,ST-elevation myocardial infarction treated by thrombolytic therapy,and non ST-elevation myocardial infarction treated by medication.A convenient sampling technique was used to recruit 206 patients with acute myocardial infarction who agreed to participate in the current study.Patients'illness perception,physical activity,and demographical and clinical data were collected during hospital admission and again at 6 months.Results:A total of 186 patients completed the study.Results showed that the primary percutaneous coronary intervention group perceived their illness as acute rather than chronic(P=0.034)and has lower personal control(P=0.032),higher treatment control(P=0.025),and higher perception of illness coherence(P=0.022)compared with patients receiving thrombolytic therapy and treated after non-ST segment infarction.Moreover,they report low control of their blood pressure(P=0.013)and less physical activity(P=0.001).Conclusion:The results of this study revealed that patients'treated with primary percutaneous coronary intervention had negative illness perception and limited behavioral changes 6 months after hospitalization in comparison with other treatment modalities such as percutaneous coronary intervention and thrombolytic treatment.Further research is recommended to confirm this association with longer follow-up study and among different cultures.
文摘Background Influenza vaccination has been clinically shown to reduce adverse cardiovascular outcomes in acute coronary syndrome (ACS) patients, but the economic perspectives can provide important data to make informed decisions. This study aimed to perform the economic evaluation of lifelong annual influenza vaccination for cardiovascular events and well-established pneumonia prevention. Methods Lifetime costs, life-expectancy, and quality-adjusted live years (QALYs) were estimated beyond one-year cycle length of a six-health states Markov model condition on whether a hospitalization for ACS, stroke, heart failure, pneumonia, no hospitalizations occurred, or death. The comparison of three age-groups of 40-49, 50-65, and 〉 65 years scenario was performed. Incremental cost-effectiveness ratio (ICER) and net monetary benefit (NMB) were presented as a societal perspective in 2016. The model robustness was determined by one-way and prob- abilistic sensitivity analyses. Results The influenza vaccination was cost-effective in all age-groups, by dominant ICERs (lower cost with higher effectiveness) which was completely lower than acceptable willingness-to-pay threshold of Thailand [160,000 THB (4,466.8 USD) per QALYs], with a great incremental value of NMB. Especially, the 50-year-old-and- above scenario was shown as the most benefit at 129,092 THB (3,603.9 USD) for each patient. Conclusions The annually additional influenza vaccination to standard treatment in ACS was cost-effective in all age-groups, which should be considered in clinical practice and health-policy making process.
文摘The breeding and communication of cult are all realized on the base of psychological activities, psychological factors play an important role in preventing and resisting breeding and communication of cult, and in this paper, it demonstrates respectively at this point, and starts from forming the long-term mechanism of the Chinese cult governance and proposes the conception and specific suggestions accordingly of establishing the national psychological assistance system to prevent and resist breeding and communication of cult
文摘This paper attempts to analyze Blanche's psyche in relation to her employing defense mechanism to restore her mental health and herself in A Streetcar Named Desire (1947) by the American playwright Tennessee Williams. It focuses on her replacing reality with fantastic embodiments or illusion. She has taken unacceptable impulses into acceptable forms by unconsciously blocking the impulses such as superego and thereby reducing agony for the earlier traumatic experiences left indelible marks on her mind, and anxiety for survival. Her anxiety becomes too overwhelming that her ego urgently employs defense mechanisms to protect her. With her new hopes and dreams she desires to replace the highly stressful loss. Under mental and social stress, her illusion and her falsification of reality nevertheless became unable to overcome recurring trauma-causing situation in reality and her healing process thereby leaving her on the verge of extinction.
文摘Shopping malls are accessed by people from all walks of life and, therefore, provision of adequate fire safety measures is equally important. In Dares Salaam, Tanzania, at large construction, use of shopping malls is a relatively new experience, and risks associated with use of shopping malls, such as fire outbreak, are not evident to frequent users. The main purpose of the study is to assess awareness of fire safety measures for users and staff of two shopping malls located in Dares Salaam. The research adopted a case study strategy, and 100 respondents were involved in the study. Both random and purposive sampling methods were used to select respondents for the study. Multiple sources of evidence were used in data collection, namely literature review, observations, questionnaires and interviews. Findings indicate that both shopping malls have in place fairly fire prevention measures with varying degrees. Majority of staff and users indicated that they know fire safety measures but their poor knowledge was reflected in assessing them on diferent equipment and installations, such as foam, hose reel, sprinklers and drenchers. The paper concludes that awarenes of fire safety measure of users and staff of the two shopping malls is relatively low. It is, therefore, recommended that provision of fire safety training and instructions, such as posters for users and seminars for staff of shopping malls, shall be a main focus of shopping malls owners and responsible authorities.
基金Grant from National Institute of Infectious Diseases(NIID)National Department Public Benefit Research Foundation (201103032)
文摘The World Health Organization (WHO) standard assay for determining antibody level is the rapid fluorescent focus inhibition test (RFFIT) and is used to determine the degree of immunity after vaccination against rabies. To compare the difference in RFFIT results between the laboratories of The National Institute of Infectious Disease in Japan (NIID) and the Chinese Centre for Disease Control (CCDC) as well the influence of the choice of standard serum (STD) for the detection, the two laboratories detection methods were simultaneously manipulated by RFFIT. The reference serums used in NIID and the WHO standard serum used in CCDC were compared in the same RFFIT detection to determine the titer of four sera samples C1, Sl, S2 and S4 in parallel, and the titers of the detected sera samples were calculated using the standard formula for neutralizing antibody titer. No significant difference was found in RFFIT methods from the two laboratories and the RFFIT testing procedures of the two laboratories have good consistency. However, different titers were obtained with the tentative internal standard serum (TI-STD) produced by adjusting to 2.0 IU of WHO standard serum in NIID and the WHO STD. The titer determined with the TI-STD was higher than that determined with WHO STD, This difference appears to be significant and requires further investigation
基金Projects(51009053,51079039)supported by the National Natural Science Foundation of ChinaProject(20100094120004)supported by the Doctoral Program of Higher Education of China
文摘The joint of clay core-wall and concrete cut-off wall is one of the weakest parts in high earth and rockftll dams.A kind of highly plastic clay is always fixed on the joint to fit the large shear deformation between clay core-wall and concrete cut-offwall,so the hydro-mechanical coupling mechanisms on the joint under high stress,high hydraulic gradient,and large shear deformation are of great importance for the evaluation of dam safety.The hydro-mechanical coupling characteristics of the joint of the highly plastic clay and the concrete cut-off wall in a high earth and rockfill dam in China were studied by using a newly designed soil-structure contact erosion apparatus.The experimental results indicate that:1) Shear failure on the joint is due to the hydro-mechanical coupling effect of stress and seepage failure.The seepage failure will induce the final shear failure when the ratio of deviatoric stress to confining pressure is within 1.0-1.2; 2) A negative exponential permeability empirical model for the joint denoted by a newly defined principal stress function,which considers the coupling effect of confining pressure and axial pressure on the permeability,is established based on hydro-mechanical coupling experiments.3) The variation of the settlement before and after seepage failure is very different.The settlement before seepage failure changes very slowly,while it increases significantly after the seepage failure.4) The stress-strain relationship is of a strain softening type.5) Flow along the joint still follows Darcian flow rule.The results will provide an important theoretical basis for the further evaluation on the safety of the high earth and rockfill dam.
文摘Two-dimensional physical models of low crested breakwaters were tested to establish the effect of water depth, crest width, slope, stone size, core permeability and incident wave characteristics on the wave transformation processes. The structure of the breakwaters can be used as coastal protection system by reducing the amount of incoming wave energy. Effect of slope, core permeability, water depth and incident wave characteristics on the stability was also studied. The breakwater model consisted of a core and two armour layers attacked by irregular waves. This paper discusses and compares the test results with the existing design equations. In general, the existing design equations do not seem to predict the wave transmission and reflection accurately for the range of test data. In the range of variable tested, it was observed that the water depth, crest width and wave period have a significant influence on wave transmission process. Further, results show strong influence of the water depth and wave period on the wave reflection process. The structural stability of low crested breakwaters is very much affected by the water depth and wave period.