The structure, separation principle and feasibility research for a new type of vehicle air filter called the high speed rotary positive air filter were described. The analysis of the experimental data showed that the ...The structure, separation principle and feasibility research for a new type of vehicle air filter called the high speed rotary positive air filter were described. The analysis of the experimental data showed that the principle and structure of it were feasible and it possessed high separation efficiency and great self cleaning ability. Compared with the conventional air filter it also has lower air intake loss. So it is worth further practical research.展开更多
Binzhou section of Changshen highway was selected to study the effectiveness of road sweeping in decreasing the pollutant loads of highway runoff.With on-site continuous sampling the discharge rules of Cu Cd Pb and Zn...Binzhou section of Changshen highway was selected to study the effectiveness of road sweeping in decreasing the pollutant loads of highway runoff.With on-site continuous sampling the discharge rules of Cu Cd Pb and Zn are analyzed.The total and dissolved event mean concentrations of Cu Pb and Zn are calculated and the loads of heavy metals attached to particles sampled before and after rainfall are also studied.A test section on highway road was swept in different frequencies during a week and the amount of removed particles was measured.Based on the analysis of highway runoff and road sweeping a prediction equation is established to calculate the pollution control efficiency of the sweeping measure and the results indicate that the 1 time/week road sweeping method can remove 47.93% of dissolved Cu 46.87% of Pb and 44.21% of Zn.展开更多
AIM: To assess H pylori seroprevalence in lung cancer and determine whether there is a potential association between lung cancer and H pylori infection. METHODS: The study was conducted on forty consecutive patients w...AIM: To assess H pylori seroprevalence in lung cancer and determine whether there is a potential association between lung cancer and H pylori infection. METHODS: The study was conducted on forty consecutive patients with lung cancer, confirmed by pathology (32 men, 8 women; mean age 55.50 ± 11.91 years, range 16-77 years). Forty healthy subjects (25 men, 15 women; mean age 43.08 ± 12.60 years, range 20-79 years) from the patients’ family members were matched to each case subject on the basis of age and socioeconomic status. H pylori infection was detected with a commercially available immunoglobulin G (IgG) enzyme-linked immunosorbent assay (Trinity kit, Biotech co., USA), previously validated in adults (86% sensitivity, 96% specificity) against a gold standard of culture and histology. RESULTS: H pylori seropositivity was present in 52.5% of patients with lung cancer in comparison to 45.0% of healthy control subjects. Although H pylori seropositivity was more frequent in lung cancer patients than in controls, the difference did not reach statistical significance (OR = 1.35, 95% CI = 0.56-3.25; P = 0.65). In addition, there was no significant difference between cases and controls in terms of gastrointestinal symptoms. CONCLUSION: The earlier described association between H pylori infection and lung cancer was not supported in this study. Further studies with larger sample sizes should be undertaken to assess the frequency of H pylori infection in patients with lung cancer and their potential association.展开更多
AIM:To evaluate possible risk factors for the spread of hepatitis C infection and to analyze the characteristics of the epidemiological and clinical patterns among the patients with hepatitis C infection. METHODS: D...AIM:To evaluate possible risk factors for the spread of hepatitis C infection and to analyze the characteristics of the epidemiological and clinical patterns among the patients with hepatitis C infection. METHODS: During a five-year period a cross-sectional study was conducted among HCV positive individuals referred to the Ahwaz JundiShapour University Hospitals (AJSUH) and Hepatitis Clinic from 1 Sept 1999 to 1 Sept 2003. The control group consisted of first time blood donors referred to the Regional Blood Transfusion organization. Enzyme-linked immunosorbent assay and recombinant immunoblot assay anti-hepatitis C virus (HCV) tests were performed for two groups. Positive serum specimens were retested using polymerase chain reaction (PCR) for HCV RNA. Risk factors were evaluated using a questionnaire. Reported risk factors among infected subjects ("HCV-positive") were compared to those of subjects never exposed ("HCV-negative") to HCV. RESULTS: A total of 514 subjects were studied for HCV, of which 254 were HCV-positive and 260 HCV- negative donors comprised the control group. Mean age of the patients was 28.4 (Std 15.22) years. HCV-positive subjects were more likely to be of male gender (63% versus 37%). Transfusion 132 (52%), non-intravenous (n-iv) drug abuse and iv drug abuse 37 (14.5%), haemodialysis 25 (10%), receiving wounds at war and extramarital sexual activities (2.4%), tattooing (3.6%) were found to be independent risk factors of being HCV-positive. No apparent risk factors could be demonstrated in 29 (11.2%) of the positive cases. CONCLUSION: Our data indicate that a history of transfusion and iv drug abuse and haemodialysis are important risk factors for HCV infection in our area and that more careful pretransfusion screening of blood for anti- HCV must be introduced in our blood banks. Improvements in certain lifestyle patterns, and customs in this area may be essential to prevent transmission of the infection.展开更多
AIM: To investigate the seroprevalence of Helicobacter pylori (H. pylorl) and its relationship to nutritional fac- tors in female Vietnamese immigrants to Korea. METHODS: A total of 390 female immigrants from Viet...AIM: To investigate the seroprevalence of Helicobacter pylori (H. pylorl) and its relationship to nutritional fac- tors in female Vietnamese immigrants to Korea. METHODS: A total of 390 female immigrants from Vietnam and 206 Korean male spouses participated in the study. Blood samples from 321 female immigrants and 201 Korean male spouses were analyzed for H. py- Iori antibodies. Data on age, sex, alcohol consumption, smoking status, dietary nutritional factors and gastro- intestinal symptoms were collected using question- naires. The daily intakes of the following nutrients were estimated: energy, protein, niacin, lipid, fiber, calcium, iron, sodium, potassium, zinc, folate, cholesterol, and vitamins A, B1, B2, B6, C and E. RESULTS: The prevalence of H. py/ori positivity was lower in the immigrants than in age-matched Koreanfemales (55.7% vs 71.4%, respectively; P 〈 0.0001) and the domestic population of Vietnam. The preva- lence of H. pylori positivity among married couples was 31.7% for both spouses. There were no statistically sig- nificant differences in the incidence of smoking, amount of alcohol consumed, or nutritional factors between the H. pylori-positive and negative groups. CONCLUSION: The prevalence of H. pylori positivity was lower among female Vietnamese immigrants than among Korean females. Nutritional factors did not differ between the H. pylori-positive and negative groups.展开更多
AIM: To investigate the seroprevalence and molecular characteristics of hepatitis E virus (HEV) in the illegal blood donors (IBDs) of central China in the early 1990s.
AIM:To determine the seroprevalence of anti-hepatitis A virus (HAV) antibodies in patients with chronic liver disease (CLD) and to justify the need for hepatitis A vaccination.METHODS:Patients (n=119) were enrolled be...AIM:To determine the seroprevalence of anti-hepatitis A virus (HAV) antibodies in patients with chronic liver disease (CLD) and to justify the need for hepatitis A vaccination.METHODS:Patients (n=119) were enrolled between July and September 2009.The diagnosis of CLD was based on the presence of viral markers for more than 6 mo.The diagnosis of liver cirrhosis was based on clinical,biochemical and radiological profiles.Patient serum was tested for anti-HAV IgG.RESULTS:The overall anti-HAV seroprevalence was 88.2%.The aetiology of CLD was hepatitis B in 96 patients (80.7%) and hepatitis C in 23 patients (19.3%).Mean age was 44.4 ± 14 years.Patients were grouped according to age as follows:24 (20.2%) patients in the 21-30 years age group,22 (18.5%) in the 31-40 years age group,31 (26.1%) in the 41-50 years age group,23(19.3%) in the 51-60 years age group and 19 (16.0%) patients aged greater than 60 years,with reported seroprevalences of 66.7%,95.5%,93.5%,91.3% and 94.7%,respectively.There was a marked increase of seroprevalence in subjects older than 30 years (P=0.001).CONCLUSION:Our study demonstrated that patients aged greater than 30 years of age were likely to have natural immunity to hepatitis A.Therefore,hepatitis A vaccination may not be routinely required in this age group.展开更多
Historical records of metal inputs were studied by using a sediment core collected from a sand-rich mudflat in the Qinjiang River estuary, China. 210Pb chronology was used to reconstruct the fluxes of Hg, Cu, Pb, Zn, ...Historical records of metal inputs were studied by using a sediment core collected from a sand-rich mudflat in the Qinjiang River estuary, China. 210Pb chronology was used to reconstruct the fluxes of Hg, Cu, Pb, Zn, Cd, Cr and As to the core site during the last 86 years. Based on the constant initial concentration model, the sedimentation rates are 1.18 cm year-1 in the top 30 cm sandy layer and 0.92 cm year-1 in the muddy bottom layer. To compensate for grain-size and mineralogy effects on metal concentra-tions, aluminum was used as the normalizing element. The enrichment factors (EF) indicate that the natural inputs had prevailed up to the early 1980s. After this period, the intensity of human activities has resulted in continual increasing trend of metals towards the surface. Recent sediment samples from the Qinjiang River estuary are found moderately enriched by Cd (EF>1.5) and slightly enriched by other metals (EF<1.5). Considering that the drainage area of the Qinjiang River is mostly agricultural land, the increased Cd may be due to the usage of fertilizers and pesticides in agricultural activities and the combustion of fossil fuels.展开更多
This study estimates direct radiative forcing by tropospheric ozone and all aerosols between the years 1850 and 2000, using the new IPCC AR5 (the Intergovernmental Panel on Climate Change Fifth Assessment Report) em...This study estimates direct radiative forcing by tropospheric ozone and all aerosols between the years 1850 and 2000, using the new IPCC AR5 (the Intergovernmental Panel on Climate Change Fifth Assessment Report) emissions inventories and a fully coupled chemistry-aerosol general circulation model. As compared to the previous Global Emissions Inventory Activity (GEIA) data, that have been commonly used for forcing estimates since 1990, the IPCC AR5 emissions inventories report lower anthropogenic emissions of organic carbon and black carbon aerosols and higher sulfur and NOx emissions. The simulated global and annual mean burdens of sulfate, nitrate, black carbon (BC), primary organic aerosol (POA), secondary organic aerosol (SOA), and ozone were 0.79, 0.35, 0.05, 0.49, 0.34, and 269 Tg, respectively, in the year 1850, and 1.90, 0.90, 0.11, 0.71, 0.32, and 377 Tg, respectively, in the year 2000. The estimated annual mean top of the atmosphere (TOA) direct radiative forcing of all anthropogenic aerosols based on the AR5 emissions inventories is -0.60 W m^-2 on a global mean basis from 1850 to 2000. However, this is -2.40 W m-2 when forcing values are averaged over eastern China (18-45°N and 95-125°E). The value for tropospheric ozone is 0.17 W m^-1 on a global mean basis and 0.24 W m^-2 over eastern China. Forcing values indicate that the climatic effect of aerosols over eastern China is much more significant than the globally averaged effect.展开更多
AIM: To identify cancer stern cells (CSCs) in human gallbladder carcinomas (GBCs). METHODS: Primary GBC cells were cultured under serum-free conditions to produce floating spheres. The stem-cell properties of th...AIM: To identify cancer stern cells (CSCs) in human gallbladder carcinomas (GBCs). METHODS: Primary GBC cells were cultured under serum-free conditions to produce floating spheres. The stem-cell properties of the sphere-forming cells, including self-renewal, differentiation potential, chemoresistance and tumorigenicity, were determined in vitro or in vivo. Cell surface expression of CD133 was investigated in primary tumors and in spheroid cells using flow cytometry. The sphere-colony-formation ability and tumorigenicity of CD133+ cells were assayed.floating spheroids were generated from primary GBC cells, and these sphere-forming cells could generate new progeny spheroids in serum-free media. Spheroid cells were differentiated under serum-containing conditions with downregulation of the stem cell markers Oct-4, Nanog, and nestin (P 〈 0.05). The differentiated cells showed lower spheroid-colony-formation ability than the original spheroid cells (P 〈 0.05). Spheroid ceils were more resistant to chemotherapeutic reagents than the congenetic adherent cells (P 〈 0.05). Flow cytometry showed enriched CD133+ population in sphereforming cells (P 〈 0.05). CD133+ cells possessed high colony-formation ability than the CD133 population (P 〈 0.01). CD133+ cells injected into nude mice revealed higher tumorigenicity than their antigen-negative counterparts (P 〈 0.05). CONCLUSION: CD133 may be a cell surface marker for CSCs in GBC.展开更多
The accuracy of the traditional assessment method of the quality of experience(Qo E) has been facing challenges with the growth of high-definition(HD) video streaming services.Image display-quality damage is the main ...The accuracy of the traditional assessment method of the quality of experience(Qo E) has been facing challenges with the growth of high-definition(HD) video streaming services.Image display-quality damage is the main factor that affects the Qo E in HD video services through UDP network transmission.In this paper,we introduce a novel objective factor known as image damage accumulation(IDA) to assess user's Qo E in HD video services.First,this paper quantitatively analyzed the effect on user quality of experience by IDA and established a mapping relationship between mean opinion scores and IDA.Furthermore,the probability of image damage caused by compression and transmission were analyzed.Based on this analysis,an objective Qo E assessment and prediction method for HD video stream service that evaluated the user experience according to IDA are proposed.The proposed method can achieve assessment and prediction accuracy on three distinct subjective tests.展开更多
AIM: To fi nd the current seroepidemiology of hepatitis A virus (HAV) in Kuwait.METHODS: A total of 2851 Kuwaitis applying for new jobs were screened.RESULTS: HAV-positive cases were 28.8%; 59% were males and 41% were...AIM: To fi nd the current seroepidemiology of hepatitis A virus (HAV) in Kuwait.METHODS: A total of 2851 Kuwaitis applying for new jobs were screened.RESULTS: HAV-positive cases were 28.8%; 59% were males and 41% were females. The highest prevalence was in the Ahmadi area. High prevalence was among the group of non-educated rather than educated parents. This is the fi rst study in Kuwait demonstrating the shifting epidemiology of HAV.CONCLUSION: This study reflects the need of the Kuwaiti population for an HAV vaccine.展开更多
AIM: To determine the seroprevalence of Hepatitis A (HAV) amongst Saudi children and compare it with previously reported prevalence data from the same population. METHODS: A total of 1357 students were randomly se...AIM: To determine the seroprevalence of Hepatitis A (HAV) amongst Saudi children and compare it with previously reported prevalence data from the same population. METHODS: A total of 1357 students were randomly selected between the ages of 16 and 18 years (689 males and 668 females) from three different regions of Saudi Arabia (Madinah, AI-Qaseem, and Aseer) and tested for anti-HAV-IgG.RESULTS: The overall prevalence of anti-HAV-IgG among the study population was 18.6%. There was no difference between males and females but there was a significant difference in the seroprevalence (P = 0.0001) between the three different regions, with Madinah region showing the highest prevalence (27.4%). When classified according to socioeconomic status, lower class students had a prevalence of 36.6%, lower middle class 16.6%, upper middle class 9.6%, and upper class 5.9% (P = 0.0001). Comparing the current study results with those of previous studies in 1989 and 1997 involving the same population, there was a marked reduction in the overall prevalence of HAV from 52% in 1989, to 25% in 1997, to 18.6% in 2008 (P 〈 0.0001).CONCLUSION: Over the last 18 years, there has been a marked decline in the prevalence of HAV in Saudi children and adolescents. The current low prevalence rates call for strict adherence to vaccination policies in high-risk patients and raises the question of a universal HAV vaccination program.展开更多
AIM: To analyze the hemodynamic and respiratory effects of propofol on patients undergoing gastroscopy and colonoscopy. METHODS: In this prospective study, conducted over a period of three years, 1,104 patients refe...AIM: To analyze the hemodynamic and respiratory effects of propofol on patients undergoing gastroscopy and colonoscopy. METHODS: In this prospective study, conducted over a period of three years, 1,104 patients referred for a same day GI endoscopy procedure were analyzed. All patients were given a propofol bolus (0.5-1.5 mg/kg). Arterial blood pressure (BP) was monitored at 3 rain intervals and heart rate and oxygen saturation (SpO2) were recorded continuously by pulse oximetry. Analyzed data acquisition was carried out before, during, and after the procedure. RESULTS: A statistically significant reduction in mean arterial pressure was demonstrated (P〈0.001) when compared to pre-intervention values, but severe hypotension, defined as a systolic blood pressure below 60mmHg, was noted in only 5 patients (0.5%). Oxygen saturation decreased from 96.5% to 94.4 % (P〈0.001). A critical decrease in oxygen saturation (〈90%) was documented in 27 patients (2.4%). CONCLUSION: Our results showed that propofol provided good sedation with excellent pain control, a short recovery time and no significant hemodynamic side effelts if carefully titrated. All the patients (and especially ASA Ⅲ group) require monitoring and care of an anesthesiologist.展开更多
文摘The structure, separation principle and feasibility research for a new type of vehicle air filter called the high speed rotary positive air filter were described. The analysis of the experimental data showed that the principle and structure of it were feasible and it possessed high separation efficiency and great self cleaning ability. Compared with the conventional air filter it also has lower air intake loss. So it is worth further practical research.
基金The National Science and Technology Major Project of China(No.2008ZX07010-008-04)
文摘Binzhou section of Changshen highway was selected to study the effectiveness of road sweeping in decreasing the pollutant loads of highway runoff.With on-site continuous sampling the discharge rules of Cu Cd Pb and Zn are analyzed.The total and dissolved event mean concentrations of Cu Pb and Zn are calculated and the loads of heavy metals attached to particles sampled before and after rainfall are also studied.A test section on highway road was swept in different frequencies during a week and the amount of removed particles was measured.Based on the analysis of highway runoff and road sweeping a prediction equation is established to calculate the pollution control efficiency of the sweeping measure and the results indicate that the 1 time/week road sweeping method can remove 47.93% of dissolved Cu 46.87% of Pb and 44.21% of Zn.
文摘AIM: To assess H pylori seroprevalence in lung cancer and determine whether there is a potential association between lung cancer and H pylori infection. METHODS: The study was conducted on forty consecutive patients with lung cancer, confirmed by pathology (32 men, 8 women; mean age 55.50 ± 11.91 years, range 16-77 years). Forty healthy subjects (25 men, 15 women; mean age 43.08 ± 12.60 years, range 20-79 years) from the patients’ family members were matched to each case subject on the basis of age and socioeconomic status. H pylori infection was detected with a commercially available immunoglobulin G (IgG) enzyme-linked immunosorbent assay (Trinity kit, Biotech co., USA), previously validated in adults (86% sensitivity, 96% specificity) against a gold standard of culture and histology. RESULTS: H pylori seropositivity was present in 52.5% of patients with lung cancer in comparison to 45.0% of healthy control subjects. Although H pylori seropositivity was more frequent in lung cancer patients than in controls, the difference did not reach statistical significance (OR = 1.35, 95% CI = 0.56-3.25; P = 0.65). In addition, there was no significant difference between cases and controls in terms of gastrointestinal symptoms. CONCLUSION: The earlier described association between H pylori infection and lung cancer was not supported in this study. Further studies with larger sample sizes should be undertaken to assess the frequency of H pylori infection in patients with lung cancer and their potential association.
文摘AIM:To evaluate possible risk factors for the spread of hepatitis C infection and to analyze the characteristics of the epidemiological and clinical patterns among the patients with hepatitis C infection. METHODS: During a five-year period a cross-sectional study was conducted among HCV positive individuals referred to the Ahwaz JundiShapour University Hospitals (AJSUH) and Hepatitis Clinic from 1 Sept 1999 to 1 Sept 2003. The control group consisted of first time blood donors referred to the Regional Blood Transfusion organization. Enzyme-linked immunosorbent assay and recombinant immunoblot assay anti-hepatitis C virus (HCV) tests were performed for two groups. Positive serum specimens were retested using polymerase chain reaction (PCR) for HCV RNA. Risk factors were evaluated using a questionnaire. Reported risk factors among infected subjects ("HCV-positive") were compared to those of subjects never exposed ("HCV-negative") to HCV. RESULTS: A total of 514 subjects were studied for HCV, of which 254 were HCV-positive and 260 HCV- negative donors comprised the control group. Mean age of the patients was 28.4 (Std 15.22) years. HCV-positive subjects were more likely to be of male gender (63% versus 37%). Transfusion 132 (52%), non-intravenous (n-iv) drug abuse and iv drug abuse 37 (14.5%), haemodialysis 25 (10%), receiving wounds at war and extramarital sexual activities (2.4%), tattooing (3.6%) were found to be independent risk factors of being HCV-positive. No apparent risk factors could be demonstrated in 29 (11.2%) of the positive cases. CONCLUSION: Our data indicate that a history of transfusion and iv drug abuse and haemodialysis are important risk factors for HCV infection in our area and that more careful pretransfusion screening of blood for anti- HCV must be introduced in our blood banks. Improvements in certain lifestyle patterns, and customs in this area may be essential to prevent transmission of the infection.
文摘AIM: To investigate the seroprevalence of Helicobacter pylori (H. pylorl) and its relationship to nutritional fac- tors in female Vietnamese immigrants to Korea. METHODS: A total of 390 female immigrants from Vietnam and 206 Korean male spouses participated in the study. Blood samples from 321 female immigrants and 201 Korean male spouses were analyzed for H. py- Iori antibodies. Data on age, sex, alcohol consumption, smoking status, dietary nutritional factors and gastro- intestinal symptoms were collected using question- naires. The daily intakes of the following nutrients were estimated: energy, protein, niacin, lipid, fiber, calcium, iron, sodium, potassium, zinc, folate, cholesterol, and vitamins A, B1, B2, B6, C and E. RESULTS: The prevalence of H. py/ori positivity was lower in the immigrants than in age-matched Koreanfemales (55.7% vs 71.4%, respectively; P 〈 0.0001) and the domestic population of Vietnam. The preva- lence of H. pylori positivity among married couples was 31.7% for both spouses. There were no statistically sig- nificant differences in the incidence of smoking, amount of alcohol consumed, or nutritional factors between the H. pylori-positive and negative groups. CONCLUSION: The prevalence of H. pylori positivity was lower among female Vietnamese immigrants than among Korean females. Nutritional factors did not differ between the H. pylori-positive and negative groups.
基金Supported by The Natural Science Foundation of Maanshan,China (2008-40) (To Zhan SW and Zheng JX)
文摘AIM: To investigate the seroprevalence and molecular characteristics of hepatitis E virus (HEV) in the illegal blood donors (IBDs) of central China in the early 1990s.
基金Supported by Short term grant No. 304/PPSP/61310014 from the Universiti Sains Malaysia
文摘AIM:To determine the seroprevalence of anti-hepatitis A virus (HAV) antibodies in patients with chronic liver disease (CLD) and to justify the need for hepatitis A vaccination.METHODS:Patients (n=119) were enrolled between July and September 2009.The diagnosis of CLD was based on the presence of viral markers for more than 6 mo.The diagnosis of liver cirrhosis was based on clinical,biochemical and radiological profiles.Patient serum was tested for anti-HAV IgG.RESULTS:The overall anti-HAV seroprevalence was 88.2%.The aetiology of CLD was hepatitis B in 96 patients (80.7%) and hepatitis C in 23 patients (19.3%).Mean age was 44.4 ± 14 years.Patients were grouped according to age as follows:24 (20.2%) patients in the 21-30 years age group,22 (18.5%) in the 31-40 years age group,31 (26.1%) in the 41-50 years age group,23(19.3%) in the 51-60 years age group and 19 (16.0%) patients aged greater than 60 years,with reported seroprevalences of 66.7%,95.5%,93.5%,91.3% and 94.7%,respectively.There was a marked increase of seroprevalence in subjects older than 30 years (P=0.001).CONCLUSION:Our study demonstrated that patients aged greater than 30 years of age were likely to have natural immunity to hepatitis A.Therefore,hepatitis A vaccination may not be routinely required in this age group.
基金supported by the National Basic Research Program of China (973 Pro-gram) under grant No.2010CB951203the National 908 Program under grant No.GX908 (supplement)
文摘Historical records of metal inputs were studied by using a sediment core collected from a sand-rich mudflat in the Qinjiang River estuary, China. 210Pb chronology was used to reconstruct the fluxes of Hg, Cu, Pb, Zn, Cd, Cr and As to the core site during the last 86 years. Based on the constant initial concentration model, the sedimentation rates are 1.18 cm year-1 in the top 30 cm sandy layer and 0.92 cm year-1 in the muddy bottom layer. To compensate for grain-size and mineralogy effects on metal concentra-tions, aluminum was used as the normalizing element. The enrichment factors (EF) indicate that the natural inputs had prevailed up to the early 1980s. After this period, the intensity of human activities has resulted in continual increasing trend of metals towards the surface. Recent sediment samples from the Qinjiang River estuary are found moderately enriched by Cd (EF>1.5) and slightly enriched by other metals (EF<1.5). Considering that the drainage area of the Qinjiang River is mostly agricultural land, the increased Cd may be due to the usage of fertilizers and pesticides in agricultural activities and the combustion of fossil fuels.
基金supported by the National Natural Science Foundation of China (Grant Nos.90711004 and40825016)the Chinese Academy of Sciences (Grant Nos.KZCX2-YW-Q1 and KZCX2-YW-Q11-03)
文摘This study estimates direct radiative forcing by tropospheric ozone and all aerosols between the years 1850 and 2000, using the new IPCC AR5 (the Intergovernmental Panel on Climate Change Fifth Assessment Report) emissions inventories and a fully coupled chemistry-aerosol general circulation model. As compared to the previous Global Emissions Inventory Activity (GEIA) data, that have been commonly used for forcing estimates since 1990, the IPCC AR5 emissions inventories report lower anthropogenic emissions of organic carbon and black carbon aerosols and higher sulfur and NOx emissions. The simulated global and annual mean burdens of sulfate, nitrate, black carbon (BC), primary organic aerosol (POA), secondary organic aerosol (SOA), and ozone were 0.79, 0.35, 0.05, 0.49, 0.34, and 269 Tg, respectively, in the year 1850, and 1.90, 0.90, 0.11, 0.71, 0.32, and 377 Tg, respectively, in the year 2000. The estimated annual mean top of the atmosphere (TOA) direct radiative forcing of all anthropogenic aerosols based on the AR5 emissions inventories is -0.60 W m^-2 on a global mean basis from 1850 to 2000. However, this is -2.40 W m-2 when forcing values are averaged over eastern China (18-45°N and 95-125°E). The value for tropospheric ozone is 0.17 W m^-1 on a global mean basis and 0.24 W m^-2 over eastern China. Forcing values indicate that the climatic effect of aerosols over eastern China is much more significant than the globally averaged effect.
文摘AIM: To identify cancer stern cells (CSCs) in human gallbladder carcinomas (GBCs). METHODS: Primary GBC cells were cultured under serum-free conditions to produce floating spheres. The stem-cell properties of the sphere-forming cells, including self-renewal, differentiation potential, chemoresistance and tumorigenicity, were determined in vitro or in vivo. Cell surface expression of CD133 was investigated in primary tumors and in spheroid cells using flow cytometry. The sphere-colony-formation ability and tumorigenicity of CD133+ cells were assayed.floating spheroids were generated from primary GBC cells, and these sphere-forming cells could generate new progeny spheroids in serum-free media. Spheroid cells were differentiated under serum-containing conditions with downregulation of the stem cell markers Oct-4, Nanog, and nestin (P 〈 0.05). The differentiated cells showed lower spheroid-colony-formation ability than the original spheroid cells (P 〈 0.05). Spheroid ceils were more resistant to chemotherapeutic reagents than the congenetic adherent cells (P 〈 0.05). Flow cytometry showed enriched CD133+ population in sphereforming cells (P 〈 0.05). CD133+ cells possessed high colony-formation ability than the CD133 population (P 〈 0.01). CD133+ cells injected into nude mice revealed higher tumorigenicity than their antigen-negative counterparts (P 〈 0.05). CONCLUSION: CD133 may be a cell surface marker for CSCs in GBC.
基金supported by the 863 Program(2014AA01A701)NSFC(61271187)+1 种基金the PAPD fundthe CICAEET fund
文摘The accuracy of the traditional assessment method of the quality of experience(Qo E) has been facing challenges with the growth of high-definition(HD) video streaming services.Image display-quality damage is the main factor that affects the Qo E in HD video services through UDP network transmission.In this paper,we introduce a novel objective factor known as image damage accumulation(IDA) to assess user's Qo E in HD video services.First,this paper quantitatively analyzed the effect on user quality of experience by IDA and established a mapping relationship between mean opinion scores and IDA.Furthermore,the probability of image damage caused by compression and transmission were analyzed.Based on this analysis,an objective Qo E assessment and prediction method for HD video stream service that evaluated the user experience according to IDA are proposed.The proposed method can achieve assessment and prediction accuracy on three distinct subjective tests.
文摘AIM: To fi nd the current seroepidemiology of hepatitis A virus (HAV) in Kuwait.METHODS: A total of 2851 Kuwaitis applying for new jobs were screened.RESULTS: HAV-positive cases were 28.8%; 59% were males and 41% were females. The highest prevalence was in the Ahmadi area. High prevalence was among the group of non-educated rather than educated parents. This is the fi rst study in Kuwait demonstrating the shifting epidemiology of HAV.CONCLUSION: This study reflects the need of the Kuwaiti population for an HAV vaccine.
基金Supported by Grant Number 113-27-AT ON6/6/2007 from King Abdulaziz City for Science and Technology, Kingdom of Saudi Arabia
文摘AIM: To determine the seroprevalence of Hepatitis A (HAV) amongst Saudi children and compare it with previously reported prevalence data from the same population. METHODS: A total of 1357 students were randomly selected between the ages of 16 and 18 years (689 males and 668 females) from three different regions of Saudi Arabia (Madinah, AI-Qaseem, and Aseer) and tested for anti-HAV-IgG.RESULTS: The overall prevalence of anti-HAV-IgG among the study population was 18.6%. There was no difference between males and females but there was a significant difference in the seroprevalence (P = 0.0001) between the three different regions, with Madinah region showing the highest prevalence (27.4%). When classified according to socioeconomic status, lower class students had a prevalence of 36.6%, lower middle class 16.6%, upper middle class 9.6%, and upper class 5.9% (P = 0.0001). Comparing the current study results with those of previous studies in 1989 and 1997 involving the same population, there was a marked reduction in the overall prevalence of HAV from 52% in 1989, to 25% in 1997, to 18.6% in 2008 (P 〈 0.0001).CONCLUSION: Over the last 18 years, there has been a marked decline in the prevalence of HAV in Saudi children and adolescents. The current low prevalence rates call for strict adherence to vaccination policies in high-risk patients and raises the question of a universal HAV vaccination program.
基金Supported by "Bates" Clinic, Svetice 15, Zagreb, Croatia, in the form of grant, equipment and drugs
文摘AIM: To analyze the hemodynamic and respiratory effects of propofol on patients undergoing gastroscopy and colonoscopy. METHODS: In this prospective study, conducted over a period of three years, 1,104 patients referred for a same day GI endoscopy procedure were analyzed. All patients were given a propofol bolus (0.5-1.5 mg/kg). Arterial blood pressure (BP) was monitored at 3 rain intervals and heart rate and oxygen saturation (SpO2) were recorded continuously by pulse oximetry. Analyzed data acquisition was carried out before, during, and after the procedure. RESULTS: A statistically significant reduction in mean arterial pressure was demonstrated (P〈0.001) when compared to pre-intervention values, but severe hypotension, defined as a systolic blood pressure below 60mmHg, was noted in only 5 patients (0.5%). Oxygen saturation decreased from 96.5% to 94.4 % (P〈0.001). A critical decrease in oxygen saturation (〈90%) was documented in 27 patients (2.4%). CONCLUSION: Our results showed that propofol provided good sedation with excellent pain control, a short recovery time and no significant hemodynamic side effelts if carefully titrated. All the patients (and especially ASA Ⅲ group) require monitoring and care of an anesthesiologist.