《观察水》教学案例与分析

本教学场景是根据义务教育课程标准实验教科书科学《生命之源——水》（苏教版）中相关内容截取的。旨在引导学生通过对多种感官的运用去认识水的各种性质．能用语言、文字、图画等多种方式表达自己的发现，即描述观察水的结果．学会认识物体的各种方法．在多种液体中快速鉴别出水，从而知道水是没有颜色、没有气味、没有昧道、透明的液体；知道水有浮力，会做验证水有浮力的实验：了解水的溶解现象，能完成水的溶解实验。

利用“观察课”提高学生的科学素养

观察力是人们从事观察活动的能力,以《观察水》为例,引导学生利用自己的感官有目的地观察水,认识水的基本特征,形成科学的观察与思维习惯,提高科学素养.

我对水的沸腾实验的一些改进

苏科版八年级物理上册的《观察水的沸腾》这个实验，是学生学习物理以来的第一次分组实验，做好这个实验的重要性是不言而喻的。因为在这个实验中不仅要培养学生的观察能力、实验能力，而且要促进学生对重要物理规律的正确理解。同时，它还能培养学生的分析概括能力和语言表达能力。

Research on Embryonic Development of Loach

[Objective] Aim to know the whole process of embryonic development of loach. [Method] DOM + LHRH-A2 was used to induce spawning of loach,then after fertilization,the embryos were cultured into freshwater water with temperature from 24 to 26 ℃ and pH from 7.0 to 7.5. The embryonic development of loach was observed and 27 concrete morphological characteristics and development time of loach from fertilized egg to newly hatched larval period were described in detail. [Result] The embryonic development of loach could be divided into cleavage stage,blastocyst stage,gastrula stage,neurula stage and organogenesis stage. The loach embryo from fertilized egg to out membrane period was 30 h 45 min in fresh water from 24 to 26 ℃ and pH from 7.0 to 7.5. [Conclusion] It provided important reference for studying artificial propagation and genetic breeding of loach.

细微之处“求”科学

科学课堂中有些所谓细枝末节不但会影响教学目标的达成，而且还会影响学生的科学精神和科学态度的形成。

巧用趣味活动 开启探索科学的旅程

观察是儿童认识世界的基本方法。随着年龄的增长,儿童的观察能力逐步发展,这不仅增强了他们获取信息的能力,更有助于他们区分主观世界和客观世界。在苏教版科学一年级上册就安排了《认识感官》一课,之前认识感官的活动是安排在三年级《观察水》一课中的。那现在设计在了一年级,教师又应该如何根据学生的年龄特点进行教学设计呢?笔者结合课标的要求进行了教材的重组,对一年级科学教学进行了初探。

思维导图在科学教学设计中的应用

本文通过具体的教学实践,从教学设计方面说明思维导图在小学科学中的应用;并说明了思维导图在其中所具有的优势以及应该注意的地方。以《观察水》为课例进行了举例说明,最后对思维导图应用于教育教学的局限性以及未来的研究方向进行了说明。

Subclinical high altitude pulmonary edema: A clinical observation of 12 cases in Yushu

During the Yushu Earthquake on April 14,2010,a high incidence of acute high altitude illness was observed in the mountain rescuers,and 0.73 % of these patients suffered from high altitude pulmonary edema,of which 12 patients developed subclinical pulmonary edema and concomitantly contracted acute mountain sickness. Symptoms and signs were atypically high heart rate with high respiratory rate,striking cyanosis,and significantly low oxygen saturation,whereas no moist rates were heard on auscultation,and Chest X-ray showed peripheral with a patchy distribution of mottled infiltrations in one or both lung fields. We believe that subclinical high altitude pulmonary edema is an earliest stage of pulmonary edema at high altitude. The possible pathogenesis and the diagnosis were discussed.

Optimization of Groundwater Level Monitoring Network Using GIS-based Geostatistical Method and Multi-parameter Analysis:A Case Study in Wainganga Sub-basin,India

Groundwater is one of the most important resources, its monitoring and optimized management has now become the priority to satisfy the demand of rapidly increasing population. In many developing countries, optimized groundwater level monitoring networks are rarely designed to build up a strong groundwater level data base, and to reduce operation time and cost. The paper presents application of geostatistical method to optimize existing network of observation wells for 18 sub-watersheds within the Wainganga Sub-basin located in the central part of India. The average groundwater level fluctuation(GWLF) from 37 observation wells is compared with parameters like lineament density, recharge, density of irrigation wells, land use and hydrogeology(LiRDLH) of Wainganga Sub-basin and analyzed stochastically in Geographic Information System(GIS) environment using simple, ordinary, disjunctive and universal kriging methods. Semivariogram analyses have been performed separately for all kriging methods to fit the best theoretical model with experimental model. Results from gaussian, spherical, exponential and circular theoretical models were compared with those of experimental models obtained from the groundwater level data. Spatial analyses conclude that the exponential semivariogram model obtained from ordinary kriging gives the best fit model. Study demonstrates that ordinary kriging gives the optimal solution and additional number of observation wells can be added utilizing the error variance for optimal design of groundwater level monitoring networks. This study describes the use of Geostatistics methods in GIS to predict the groundwater level and upgrade groundwater level monitoring networks from the randomly distributed observation wells considering multiple parameters such as GWLF and LiRDLH. The method proposed in the present study is observed to be an efficient method for selecting observation well locations in a complex geological set up. The study concludes that minimum 82 wells are required for proper monitoring of groundwater level in the study area.

Observations on shell growth and morphology of the bivalve Ruditapes philippinarum

The bivalve Ruditapes philippinarum is not only one of the main mollusc species in the west Pacific Ocean, but also one of the main species for aquaculture in China. Knowledge of growth of the R. philippinarum shell will improve our understanding of the shell as an environmental archive. It is also useful for the aquaculture of R. philippinarum. In this research, a hanging box culture method was introduced in the culture of R. philippinarum. The bivalves were cultured for 126 days, from March 31 to August 3, 2002. The average growth rates of shell width, height, and thickness were 0.069, 0.046, and 0.032 mm/d, respectively. The mean increase of average individual wet mass was 0.028 g/d. The largest growth rates of both shell and average individual wet mass occurred in June, indicating that water temperature and bivalve reproduction were 2 important factors. The shell morphology underwent significant changes with shell growth. The ratio of height to thickness (value of B/C) shifted 1.58 in the first 60 days to 1.54 in the last 30 days, which was resulted from the change in major shell growth direction. Periodic changes in the B/C ratio led to corrugated shell form, which could be used to determine the age of the shell.

Hemolysis results in impaired intestinal microcirculation and intestinal epithelial cell injury

AIM:To study the effect of circulating cell-free oxy-hemoglobin(FHb) on intestinal microcirculation and intestinal epithelial injury in a rat model. METHODS:To induce elevated intravascular circulating FHb,male Sprague-Dawley rats received water or FHb infusion.Microcirculatory changes in jejunum,ileum and colon were evaluated using fluorescent microspheres.Intestinal injury was quantified as plasmatic release of ileal lipid binding protein(iLBP) and verified by histological analysis of the ileum. RESULTS:Water and FHb infusions resulted,when compared with saline infusion,in reduced intestinal microcirculation(after 30 min P<0.05,or better;after 60 min FHb infusion P<0.05 for jejunum and colon) .Circulating FHb levels correlated significantly with release of iLBP(Spearman r=0.72,P=0.0011) .Epithelial cell injury of the villi was histologically observed after water and FHb infusions. CONCLUSION:This study shows that circulating FHb leads to a reduction in intestinal microcirculatory blood flow with marked injury to intestinal epithelial cells. These data support the hypothesis that circulating FHb contributes to the development of intestinal injury.

Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)

AIM： TO establish which scolicidal agents are superior and more suitable for regular use. METHODS： Echinococcus granu/osus protoscoleces were obtained from 25 patients with liver hydatid cysts. Various concentrations of albendazole sulfone, albendazole sulfoxide, and albendazole sulfone and albendazole sulfoxide mixed together in concentrations of 50 μg/mL, and H202 in a concentration of 4%, NaCI 20%, and 1.5% cetrimide-0.15% chlorhexidine （10% Savlon-Turkey） were used to determine the scolicidal effects. Albendazole （ABZ） derivatives and other scolicidal agents were applied to a minimum of 100 scoleces for 5 and 10 min. The degree of viability was calculated according to the number of living scolices per field from a total of 100 scolices observed under the microscope. RESULTS： After 5 min, ABZ sulfone was 97.3% effective, ABZ sulfoxide was 98.4% effective, and the combined solution was 98.6% effective. When sulfone, sulfoxide and the combined solutions were compared, the combined solution seemed more effective than sulfone. However, there was no difference when the combined solution was compared with sulfoxide. After 10 min, hypertonic salt water, sulfone, sulfoxide, and the combined solution compared to other solutions looked more effective and this was statistically significant on an advanced level. When sulfone, sulfoxide, and the combined solutions were compared with each other, the combined solution appeared more effective than sulfone. When the combined solution was compared with sulfoxide, there was no difference. CONCLUSION： Despite being active, ABZ metabolites did not provide a marked advantage over 20% hypertonic saline. According to these results, we think creating a newly improved and more active preparation is necessary for hydatid cyst treatment.

Efficacy of MK615 for the treatment of patients with liver disorders

AIM： To investigate the hepatoprotective effect of MK615, a Japanese apricot extract, in an animal model, and its clinical therapeutic effect. METHODS： Wistar rats were administered physiologi- cal saline （4 mL/kg） or MK615 solution （4 mL/kg） for 7 d. On the sixth d, acute hepatic injury was induced by administering a single intraperitoneal injection （ip） of D-galactosamine hydrochloride （D-GaIN） （600 mg/kg）. Plasma levels of alanine aminotransferase （ALT） and aspartate aminotransferase （AST） were determined, and liver tissues were used for histopathological analy- sis. Fifty-eight patients with liver disorders [hepatitis C （n = 40）, non-alcoholic fatty liver disease （n = 15）, and autoimmune liver disease （n = 3）] were orally admin- istered commercially available Misatol ME-containing MK615 （13 g/d） daily for 12 wk. Blood and urine were sampled immediately before and 6 wk, 12 wk, and 16 wk after the start of intake to measure various bio- chemical parameters. The percentage change in ALT and AST levels after 12 wk from the pre-intake baseline served as a primary endpoint. RESULTS： D-GaIN effectively induced acute hepatic injury in the rats. At 48 h after the ip injection of D-GaIN, the plasma levels of ALT （475.6 ：t： 191.5 IU/L vs 225.3 ＋ 194.2 IU/L, P 〈 0.05） and AST （1253.9：1：223.4 IU/L vs 621.9 ＋ 478.2 IU/L, P 〈 0.05） in the MK615 group were significantly lower than the control group. Scattered single cell necrosis, loss of hepatocytes, and extensive inflammatory cell infiltration were observed in hepatic tissue samples collected from the control group. However, these findings were less pronounced in the group receiving MK615. At the end of the clinical study, serum ALT and AST levels were significantly de- creased compared with pre-intake baseline levels from 103.5 ：l： 58.8 IU/L to 71.8 ＋ 39.3 IU/L （P 〈 0.05） and from 93.5 ：E 55.6 IU/L to 65.5 ＋ 34.8 IU/L （P 〈 0.05）, respectively. A reduction of 〉~ 30% from the pre-study baseline ALT level was observed in 26 （45%） of the 58 patients, while 25 （43%） patients exhibited similar AST level reductions. The chronic hepatitis C group exhibit- ed significant ALT and AST level reductions from 93.4：1： 51.1 IU/L to 64.6 ＋ 35.1 IU/L （P 〈 0.05） and from 94.2 ＋ 55.5 IU/L to 67.2：1：35.6 IU/L （P 〈 0.05）, respective- ly. A reduction of 〉~ 30% from the pre-study baseline ALT level was observed in 20 （50%） of the 40 patients.ALT levels in both the combined ursodeoxycholic acid （UDCA） treatment and the UDCA uncombined groups were significantly lower after Misatol ME administration. MK615 protected hepatocytes from D-GaiN-induced cytotoxicity in rats. Misatol ME decreased elevated ALT and AST levels in patients with liver disorders. CONCLUSION： These results suggest that MK615 and Misatol ME are promising hepatoprotective agents for patients with liver disorders.

Ethical Trading： The Implications of the Human Rights Watch Report on South African Fruit Exports

This paper presents an ex-ante assessment of the potential implications of the 2011 Human Rights Watch Report on the South African fruit industry. The report explicitly mentions the lack of compliance with ethical codes within the fruit industry, the prevalence of exploitative conditions for farm workers and diverse human rights abuses in farms. The report recommends import ban on culprits as well as engaging third party auditing to ensure compliance. The high vulnerability of the smallholder farmers justified the special interest in the implications on their reputation and hence their ability to access profitable export markets. Although large-scale commercial farmers are potentially at risk of reputational damage due to the Human Rights Watch Report, they are better able to cope owing to their stronger capital base. The opinions of knowledgeable industry insiders were therefore elicited through qualitative research that used a five-point Likert scale to assess perceptions about market access. On the basis of the results, it is probable that the report will lead to improved working conditions for farm workers, improved concern for consumers＇ health, and enforcement of legislation by the govemment. The negative implications involve increased competition, possibility of retailers＇ rationalising their supply base and increased evaluation that ends at the farm gate. There is also high probability of increased marginalisation of the already disadvantaged smallholder suppliers, and possible increase in costs of auditing and accreditation for the entire fruit industry. Thus, active collaboration among all stakeholders to ensure the competitiveness of the fruit industry is inevitable.

Earth Observation as a Support to Improve Water Use in Irrigated Agriculture

By the end of sixties, several satellites were launched to observe the earth; among them the Landsat missions have been important to study natural resources, especially in agriculture. Currently, Landsat 7, with some problems, and Landsat 5 are useful to evaluate crop development. A project called ＂Participatory multi-Level EO-assisted tools for Irrigation water management and Agricultural Decision-Support＂ （PLEIADES） was financed by the European Commission. This project considers eleven countries and 23 research institutions, Mexico being one of the selected countries. Landsat images are a basic tool of this project. Some of the results obtained in this study are presented in this article. By using w^getation indices obtained by the combinations of reflectances in different bands of the electromagnetic spectrum, it has been possible to estimate the behavior of several biophysical parameters of crops which are used to evaluate plant development, water stress, spatial soil variation, and the effect of plagues and crop diseases. To facilitate this process, a visor was developed, named SPIDER （System of Participatory Information Decision support and Expert knowledge for River basin management） whose use in this work is explained.

Effect of Zn content on tensile and electrochemical properties of 3003 Al alloy

The effect of Zn addition on the microstructure, tensile properties and electrochemical properties of as-annealed 3003 Al alloy was investigated through TEM observations, tensile tests and Tafel polarization analysis. High density precipitates are observed in the Zn-containing alloys and the alloy with 1.8% Zn addition also has rod-like precipitates. Tensile test results indicate that Zn has a great effect on tensile strength of 3003 Al alloy. The alloy with 1.5% Zn addition has the highest ultimate tensile strength. The electrochemical results indicate that Zn addition to 3003 Al alloy also has great impact on the corrosion potential of the 3003 A1 alloy in 0.5% NaCl solution and ethylene glycol-water solution. The corrosion potential varies with the Zn content and shifts negatively.

Progresses on microwave remote sensing of land surface parameters

Highly accurate observations at various scales on the land surface are urgently needed for the studies of many areas,such as hydrology,meteorology,and agriculture.With the rapid development of remote sensing techniques,remote sensing has had the capacity of monitoring many factors of the Earth's land surface.Especially,the space-borne microwave remote sensing systems have been widely used in the quantitative monitoring of global snow,soil moisture,and vegetation parameters with their all-weather,all-time observation capabilities and their sensitivities to the characteristics of land surface factors.Based on the electromagnetic theories and microwave radiative transfer equations,researchers have achieved great successes in the microwave remote sensing studies for different sensors in recent years.This article has systematically reviewed the progresses on five research areas including microwave theoretical modeling,microwave inversion on soil moisture,snow,vegetation and land surface temperatures.Through the further enrichment of remote sensing datasets and the development of remote sensing theories and inversion techniques,remote sensing including microwave remote sensing will play a more important role in the studies and applications of the Earth systems.