Since bamboo has the advantages of straight grain, beautiful color, high strength and toughness, and excellent abrasion resistance, bamboo-based panels have been widely used in the fields of vehicle, construction, shi...Since bamboo has the advantages of straight grain, beautiful color, high strength and toughness, and excellent abrasion resistance, bamboo-based panels have been widely used in the fields of vehicle, construction, ship building, furniture, and decoration to partly take the place of wood, steel, plastic etc in China. This paper briefly described the basic component units, including strip, sliver, and particle, of bamboo-based panel and pointed out that to design the structure of bamboo-based panels should follow the principle of symmetric structure, surface forming method, and structuring principle of equalizing stress. According to the processing methods and formation of component units, the authors classified the bamboo-based panels in China into 13 types and presented the manufacturing technique and uses of the bamboo products, such as plybamboo, bamboo flooring, and bamboo-wood composite products in detail. In the last part of the paper, much information were offered on the output, market, and selling prospect of each type of bamboo-based panels.展开更多
With the urgent shortage of forest resource in China, using agro-residues as raw materials of composite become increasingly important. Agro-residue is the most potential fiber resource, which is helpful to sustainable...With the urgent shortage of forest resource in China, using agro-residues as raw materials of composite become increasingly important. Agro-residue is the most potential fiber resource, which is helpful to sustainable development of composite industries in China. Based on a great deal of researches, this paper summarized and discussed some problems in using agro-residues as raw materials of composites, including raw material preparation, hot-pressing, bonding technology, preventing composite from going moldy. It is proposed that to manufacture the composite of rice straws or wheat straws, the isocayante resin is a suitable adhesive, and the appropriate technologies, bonding, and treatment measures are also needed.展开更多
Based on the achievements of domestic and foreign scholars,the concept of the creativity support system(CSS)is introduced and two basic characteristics of the CSS are concluded:one is based on information technology,t...Based on the achievements of domestic and foreign scholars,the concept of the creativity support system(CSS)is introduced and two basic characteristics of the CSS are concluded:one is based on information technology,the other is assisting users in creatively solving problems.Then,the rationale as well as the correlative knowledge of the creativity support system is analyzed.Finally,according to the software that has been developed,the creativity support system's characteristics of the function is discussed.展开更多
Pride and Prejudice is an appealing novel with the graciously ironic style written by Jane Aust--British realistic female novelist. This novel without much grievance and pretence in the 18th century presents a vivid p...Pride and Prejudice is an appealing novel with the graciously ironic style written by Jane Aust--British realistic female novelist. This novel without much grievance and pretence in the 18th century presents a vivid picture of the real life of a small English town. This paper attempts to explore the artistic features through three aspects, namely, deliberate artistic plans, unique characterizations and rich and colorful languages.展开更多
The age hardening behavior of gravity cast B356 aluminum alloy was investigated by differential scanning calorimetry(DSC), hardness measurements and tensile tests. Three different artificial aging temperatures were se...The age hardening behavior of gravity cast B356 aluminum alloy was investigated by differential scanning calorimetry(DSC), hardness measurements and tensile tests. Three different artificial aging temperatures were selected, namely 155, 165 and 180 °C, with heat treatment time from 40 min to 32 h. DSC analysis results show that cluster formation begins below room temperature(at around-10 °C). Since cluster formation influences the subsequent precipitation of the main strengthening β'' phase, it can be inferred that a delay between solutionizing and artificial aging has a detrimental effect on the mechanical properties of the alloy. It was also confirmed that the hardness and the tensile properties of the alloy reach the maximum values when β'' phase is completely developed during the artificial aging. This happens after 16 h for samples aged at 155 °C, after 6 h for samples aged at 165 °C and after 4 h for samples aged at 180 °C. A subsequent decrease of the mechanical properties, observed only in the sample aged at the highest temperature, with increasing aging time can be associated with the transformation of the coherent β'' phase into the semi-coherent β' phase. Finally, the activation energy associated with the precipitation of β'' phase was calculated to be 57.2 k J/mol.展开更多
AIM: To investigate the inhibitory effects of hepatitis B virus (HBV) replication and expression by transfecting artificial microRNA (amiRNA) into HepG2.2.15 cells. METHODS: Three amiRNA-HBV plasmids were constructed ...AIM: To investigate the inhibitory effects of hepatitis B virus (HBV) replication and expression by transfecting artificial microRNA (amiRNA) into HepG2.2.15 cells. METHODS: Three amiRNA-HBV plasmids were constructed and transfected into HepG2.2.15 cells. HBV antigen secretion was detected in the cells with transient and stable transfection by time-resolved fluoroimmunoassays (TRFIA). HBV DNA replication was examined by ? uorescence quantitative PCR, and the level of HBV S mRNA was measured by semi- quantitative RT-PCR. RESULTS: The efficiency of transient transfection of the vectors into 2.2.15 cells was 55%-60%. All the vectors had significant inhibition effects on HBsAg and HBeAg at 72 h and 96 h after transfection (P < 0.01 for all). The secretion of HBsAg and HBeAg into the supernatant was inhibited by 49.8% ± 4.7% and 39.9% ± 6.7%, respectively, at 72 h in amiRNA- HBV-S608 plasmid transfection group. The copy of HBV DNA within culture supernatant was also significantly decreased at 72 h and 96 h after transfection (P <0.01 for all). In the cells with stable transfection, the secretion of HBsAg and HBeAg into the supernatant was significantly inhibited in all three transfection groups (P < 0.01 for all, vs negative control). The copies of HBV DNA were inhibited by 33.4% ± 3.0%, 60.8% ± 2.3% and 70.1% ± 3.3%, respectively. CONCLUSION: In HepG2.2.15 cells, HBV replication and expression could be inhibited by artif icial microRNA targeting the HBV S coding region. Vector-based artificial microRNA could be a promising therapeutic approach for chronic HBV infection.展开更多
To solve soil shortage in reclaiming subsided land of coal mines, the principal chemical properties of artificial soil formed by mixing organic furfural residue and inorganic fly ash were examined. The results indicat...To solve soil shortage in reclaiming subsided land of coal mines, the principal chemical properties of artificial soil formed by mixing organic furfural residue and inorganic fly ash were examined. The results indicated that the artificial soil was suitable for agriculture use after irrigation and desalination, the available nutrients in the artificial soil could satisfy the growth demand of plants, and the pH tended to the neutrality.展开更多
In order to understand the effects of thinning on microsite conditions and natural regeneration in the larch plantation, thinning experiment was conducted in a 40-year-old Larix olgensis plantation in Qingyuan County ...In order to understand the effects of thinning on microsite conditions and natural regeneration in the larch plantation, thinning experiment was conducted in a 40-year-old Larix olgensis plantation in Qingyuan County in eastern Liaoning Province, China in 2003-2004 Five thinning treatments (0%, 10.2%, 19.8%, 29.7% and 40.3% thinned) were designed on the same site. After thinning, canopy openness and the microsite conditions such as photosynthetic photon flux density (PPFD), soil moisture content, and soil temperature were measured in one growing season. Meanwhile, the investigation of natural regeneration was conducted at the end of the growing season. The results showed that the canopy openness increased with the increase of thinning intensities. PPFD and soil temperature and soil moisture content in different soil layers were positively relative with canopy openness after thinning. The richness of regenerating tree species did not significantly increase (p=0.30) after one growing season since thinning, but the regeneration density and frequency of tree species increased significantly (p〈0.05). In addition, the number of regenerating tree species increased, and the increment was correlated with the characteristics of iudividual tree species. The increasing percentage of regenerating seedlings of the shade-intolerant tree species was more than that of shade-tolerant tree species. Among the investigated regeneration species, the biggest response of seedling emergency to the canopy openness was Phellodendron amurense. This paper confirmed the following conclusions: after thinning, the variety of regenerating tree species was correlative with the characteristics of regenerating tree species, and the distribution of unthinned trees and the site conditions in the investigated larch plantation were the additional factors influencing, the regeneration.展开更多
A two-stage oxidation—alkali leaching—acid leaching method was proposed to recovery Fe,V,and Ti in modified Ti-bearing blast furnace slag.The optimal experiment conditions of iron extraction were one-stage oxidation...A two-stage oxidation—alkali leaching—acid leaching method was proposed to recovery Fe,V,and Ti in modified Ti-bearing blast furnace slag.The optimal experiment conditions of iron extraction were one-stage oxidation time 40 s and holding time 8 min.The recovery rate of iron was 89.93%.The optimum experiment conditions of vanadium extraction were total oxidation time of 126 s,NaOH concentration of 4.0 mol/L,leaching temperature of 95℃,leaching time of 90 min,and the number of cycle was 4.The leaching rate of vanadium was 92.13%.The optimal experiment conditions of titanium extraction were HCl concentration of 4.5 mol/L,leaching temperature of 75℃,and leaching time of 90 min.The TiO_(2)content of synthetic rutile was 98.61%.展开更多
This study is aimed at investigating the potentials of ex vivo expansion and pluri-differentiation of cryopreservation of adult human bone marrow mesenchymal stem cells (hMSCs) into chondrocytes, adipocytes and neur...This study is aimed at investigating the potentials of ex vivo expansion and pluri-differentiation of cryopreservation of adult human bone marrow mesenchymal stem cells (hMSCs) into chondrocytes, adipocytes and neurocytes. Cryopreserved hMSCs were resuscitated and cultured for 15 passages, and then induced into chondrocytes, adipocytes and neurocytes with corresponding induction medium. The induced cells were observed for morphological properties and detected for expressions of type II collagen, triglyceride or neuron-specific enolase and nestin. The result showed that the resuscitated cells could differentiate into chondrocytes after exposure to transforming growth factor 61 (TGF-~0, insulin-like growth factor I (IGF-I) and vitamin C (Vc), and uniformly changed morphologically from a spindle-like fibroblastic appearance to a polygonal shape in three weeks. The induced cells were heterochromatic to safranin O and expressed cartilage matrix-procollagenal (If) mRNA. The resuscitated cells cultured in induction medium consisting of dexamethasone, 3-isobutyl-l-methylxanthine, indomethacin and IGF-I showed adipogenesis, and lipid vacuoles accumulation was detectable after 21 d. The resuscitated hMSCs were also induced into neurocytes and expressed nestin and neuron specific endolase (NSE) that were special surface markers associated with neural cells at different stage. This study suggested that the resuscitated hMSCs should be still a population ofpluripotential cells and that it could be used for establishing an abundant bMSC reservoir for further experiment and treatment of various clinical discases.展开更多
Combined with recent historical climate data and two periods of land use datasets from remote sensing data, we test the net primary productivity (NPP) data sets in North Chinamodelled by the satellite data-driven Glob...Combined with recent historical climate data and two periods of land use datasets from remote sensing data, we test the net primary productivity (NPP) data sets in North Chinamodelled by the satellite data-driven Global Production Efficiency Model (GLO-PEM) for detecting thewidespread spatial and temporal characteristics of the impacts of climate and land use change onthe regional NPP. Our results show that over the past 20 years, the mean annual temperature in thestudy region has remarkably increased by more than 0.064 ℃, but over the same period, there hasbeen a 1.49 mm decrease in annual precipitation and decrease in NPP by an annual rate of 6.9 TgC.The NPP changes in the study region were greatly affected by the average temperature andprecipitation by ten-day periods as well as the seasonal temperature and precipitation in the studyregion. The correlation between seasonal NPP and seasonal precipitation and temperature is highlyconsistent with land cover spatially, and the correlation coefficient changes with the changes ofvegetation types. The analysis reveals that the related areas in land use change only take up 5.45%of the whole studied region, so the climate changes dominate the impacts on the NPP in the wholestudy region (90% of the total). However, land use plays an absolute dominative role in areas withland cover changes, accounting for 97% of the total. From 1981 to 2000, the NPP in the whole studyregion remarkably reduced due to obvious precipitation decrease and temperature rise. Between twoperiods of land use (about 10 years), the changes in climate are predicted to promote a decrease inNPP by 78 ( + -0.6) TgC, and integrated impacts of climate changes and land use to promote adecrease in NPP by 87(+-0.8) TgC.展开更多
The land desertification in Xinjiang was monitored and analyzed based on RS and GIS techniques. Satellite data interpretation was adopted to obtain the general situation of Xinjiang’s land desertification in assistan...The land desertification in Xinjiang was monitored and analyzed based on RS and GIS techniques. Satellite data interpretation was adopted to obtain the general situation of Xinjiang’s land desertification in assistance with the sampling method and on-the-spot investigations. Related monitoring and investigations showed that Xinjiang was facing with severe wide range land desertification, and its desertified area made up 77.08% of the total monitoring area. As for land types, the desertified farmland accounted for 1.92% of the total monitoring area, desertified woodland 4%, desertified grassland 45%, and unused land 49%. Accordingly, as for desertification degrees, non-desertified land occupied 22.92%, weak desertified land 5.69%, medium-degree desertified land 16.58%, severe desertified land 33.19% and super severe desertified land 21.61%. Finally, as for inducing factors, wind-eroded desertification made up 58.23%, water-eroded desertification 8.69%, salinization desertification 6.52% and frozen-melt eroded desertification 3.64%. Xinjiang’s land desertification tended to get worse and the harnessing mission remained hard.展开更多
It is easy for teenagers to view pornographic pictures on social networks. Many researchers have studied the detection of real pornographic pictures, but there are few studies on those that are artificial. In this wor...It is easy for teenagers to view pornographic pictures on social networks. Many researchers have studied the detection of real pornographic pictures, but there are few studies on those that are artificial. In this work, we studied how to detect artificial pornographic pictures, especially when they are on social networks. The whole detection process can be divided into two stages: feature selection and picture detection. In the feature selection stage, seven types of features that favour picture detection were selected. In the picture detection stage, three steps were included. 1) In order to alleviate the imbalance in the number of artificial pornographic pictures and normal ones, the training dataset of artificial pornographic pictures was expanded. Therefore, the features which were extracted from the training dataset can also be expanded too. 2) In order to reduce the time of feature extraction, a fast method which extracted features based on the proportionally scaled picture rather than the original one was proposed. 3) Three tree models were compared and a gradient boost decision tree (GBDT) was selected for the final picture detection. Three sets of experimental results show that the proposed method can achieve better recognition precision and drastically reduce the time cost of the method.展开更多
An artificial neural network is used to predict the performance of fabrics in clothing manufacturing. The predictions are based on fabric mechanical properties measured on the FAST system. The influences of the differ...An artificial neural network is used to predict the performance of fabrics in clothing manufacturing. The predictions are based on fabric mechanical properties measured on the FAST system. The influences of the different ANNs construct on the convergence speed and the prediction accuracy are investigated. The result indicates that the BP neural network is an efficiency technique and has a wide prospect in the application to garment processing.展开更多
AIM: To investigate the role of artifi cial neural networks in predicting the presence of thyroid disease in atrophic body gastritis patients. METHODS: A dataset of 29 input variables of 253 atrophic body gastritis pa...AIM: To investigate the role of artifi cial neural networks in predicting the presence of thyroid disease in atrophic body gastritis patients. METHODS: A dataset of 29 input variables of 253 atrophic body gastritis patients was applied to artifi cial neural networks (ANNs) using a data optimisation procedure (standard ANNs,T&T-IS protocol,TWIST protocol). The target variable was the presence of thyroid disease. RESULTS: Standard ANNs obtained a mean accuracy of 64.4% with a sensitivity of 69% and a specifi city of 59.8% in recognizing atrophic body gastritis patients with thyroid disease. The optimization procedures (T&T-IS and TWIST protocol) improved the performance of the recognition task yielding a mean accuracy,sensitivity and specifi city of 74.7% and 75.8%,78.8% and 81.8%,and 70.5% and 69.9%,respectively. The increase of sensitivity of the TWIST protocol was statistically signifi cant compared to T&T-IS. CONCLUSION: This study suggests that artificial neural networks may be taken into consideration as a potential clinical decision-support tool for identifying ABG patients at risk for harbouring an unknown thyroid disease and thus requiring diagnostic work-up of their thyroid status.展开更多
With the rapid development of space technology,earth observation tech nology and sky observatory technolo-gy,they have played a more and more im portant part in monitoring and predi cting of earthquakes and volcanoes ...With the rapid development of space technology,earth observation tech nology and sky observatory technolo-gy,they have played a more and more im portant part in monitoring and predi cting of earthquakes and volcanoes i n the terres-trial land.In recent years,the rela ted agencies have done the experimen ts and researches on monitoring and p redicting of earthquakes and volcanoes in the forewarning period by means of many appr oaches,such as satellite thermal in frared re-mote sensing(TIRS),Global Positioning System(GPS),differential interferometric syn thesis aperture radar(D-INSAR),astronomical time-latitude residual anomaly,and Geographic Information Systems (GIS),etc.A quite large number of re-search foundation has been built in t he fundamental theories and applica tion methods.The experiments and re searches have shown that these technology is e fficient methods for high frequency crust movement.If the existed separate scientific forces and results are possibly asse mbled together to form a more complete integration monitoring system wit h the combina-tion of space,sky observation,grou nd,deep geology and macro anomaly,i t will come into a new stage of monitoring and predicting of earthquakes and volca nic eruptions.展开更多
基金This study was supported by National 9th-Five-Year Plan Project (No. 96-011-02-07-02).
文摘Since bamboo has the advantages of straight grain, beautiful color, high strength and toughness, and excellent abrasion resistance, bamboo-based panels have been widely used in the fields of vehicle, construction, ship building, furniture, and decoration to partly take the place of wood, steel, plastic etc in China. This paper briefly described the basic component units, including strip, sliver, and particle, of bamboo-based panel and pointed out that to design the structure of bamboo-based panels should follow the principle of symmetric structure, surface forming method, and structuring principle of equalizing stress. According to the processing methods and formation of component units, the authors classified the bamboo-based panels in China into 13 types and presented the manufacturing technique and uses of the bamboo products, such as plybamboo, bamboo flooring, and bamboo-wood composite products in detail. In the last part of the paper, much information were offered on the output, market, and selling prospect of each type of bamboo-based panels.
文摘With the urgent shortage of forest resource in China, using agro-residues as raw materials of composite become increasingly important. Agro-residue is the most potential fiber resource, which is helpful to sustainable development of composite industries in China. Based on a great deal of researches, this paper summarized and discussed some problems in using agro-residues as raw materials of composites, including raw material preparation, hot-pressing, bonding technology, preventing composite from going moldy. It is proposed that to manufacture the composite of rice straws or wheat straws, the isocayante resin is a suitable adhesive, and the appropriate technologies, bonding, and treatment measures are also needed.
基金The National Key Technology R&D Program of China during the 11th Five-Year Plan Period(No.2006BAH02A06)
文摘Based on the achievements of domestic and foreign scholars,the concept of the creativity support system(CSS)is introduced and two basic characteristics of the CSS are concluded:one is based on information technology,the other is assisting users in creatively solving problems.Then,the rationale as well as the correlative knowledge of the creativity support system is analyzed.Finally,according to the software that has been developed,the creativity support system's characteristics of the function is discussed.
文摘Pride and Prejudice is an appealing novel with the graciously ironic style written by Jane Aust--British realistic female novelist. This novel without much grievance and pretence in the 18th century presents a vivid picture of the real life of a small English town. This paper attempts to explore the artistic features through three aspects, namely, deliberate artistic plans, unique characterizations and rich and colorful languages.
基金funded by Regione Lombardia-MIUR (Research Program "2 MILLIMETRI" ID 30152773)
文摘The age hardening behavior of gravity cast B356 aluminum alloy was investigated by differential scanning calorimetry(DSC), hardness measurements and tensile tests. Three different artificial aging temperatures were selected, namely 155, 165 and 180 °C, with heat treatment time from 40 min to 32 h. DSC analysis results show that cluster formation begins below room temperature(at around-10 °C). Since cluster formation influences the subsequent precipitation of the main strengthening β'' phase, it can be inferred that a delay between solutionizing and artificial aging has a detrimental effect on the mechanical properties of the alloy. It was also confirmed that the hardness and the tensile properties of the alloy reach the maximum values when β'' phase is completely developed during the artificial aging. This happens after 16 h for samples aged at 155 °C, after 6 h for samples aged at 165 °C and after 4 h for samples aged at 180 °C. A subsequent decrease of the mechanical properties, observed only in the sample aged at the highest temperature, with increasing aging time can be associated with the transformation of the coherent β'' phase into the semi-coherent β' phase. Finally, the activation energy associated with the precipitation of β'' phase was calculated to be 57.2 k J/mol.
基金The National Natural Science Foundation ofChina, No. 30700698
文摘AIM: To investigate the inhibitory effects of hepatitis B virus (HBV) replication and expression by transfecting artificial microRNA (amiRNA) into HepG2.2.15 cells. METHODS: Three amiRNA-HBV plasmids were constructed and transfected into HepG2.2.15 cells. HBV antigen secretion was detected in the cells with transient and stable transfection by time-resolved fluoroimmunoassays (TRFIA). HBV DNA replication was examined by ? uorescence quantitative PCR, and the level of HBV S mRNA was measured by semi- quantitative RT-PCR. RESULTS: The efficiency of transient transfection of the vectors into 2.2.15 cells was 55%-60%. All the vectors had significant inhibition effects on HBsAg and HBeAg at 72 h and 96 h after transfection (P < 0.01 for all). The secretion of HBsAg and HBeAg into the supernatant was inhibited by 49.8% ± 4.7% and 39.9% ± 6.7%, respectively, at 72 h in amiRNA- HBV-S608 plasmid transfection group. The copy of HBV DNA within culture supernatant was also significantly decreased at 72 h and 96 h after transfection (P <0.01 for all). In the cells with stable transfection, the secretion of HBsAg and HBeAg into the supernatant was significantly inhibited in all three transfection groups (P < 0.01 for all, vs negative control). The copies of HBV DNA were inhibited by 33.4% ± 3.0%, 60.8% ± 2.3% and 70.1% ± 3.3%, respectively. CONCLUSION: In HepG2.2.15 cells, HBV replication and expression could be inhibited by artif icial microRNA targeting the HBV S coding region. Vector-based artificial microRNA could be a promising therapeutic approach for chronic HBV infection.
文摘To solve soil shortage in reclaiming subsided land of coal mines, the principal chemical properties of artificial soil formed by mixing organic furfural residue and inorganic fly ash were examined. The results indicated that the artificial soil was suitable for agriculture use after irrigation and desalination, the available nutrients in the artificial soil could satisfy the growth demand of plants, and the pH tended to the neutrality.
基金This study was supported by “the 100-Young-Research Project” of Chinese Academy of Sciences and National Natural Science Foundation of China (30371149)
文摘In order to understand the effects of thinning on microsite conditions and natural regeneration in the larch plantation, thinning experiment was conducted in a 40-year-old Larix olgensis plantation in Qingyuan County in eastern Liaoning Province, China in 2003-2004 Five thinning treatments (0%, 10.2%, 19.8%, 29.7% and 40.3% thinned) were designed on the same site. After thinning, canopy openness and the microsite conditions such as photosynthetic photon flux density (PPFD), soil moisture content, and soil temperature were measured in one growing season. Meanwhile, the investigation of natural regeneration was conducted at the end of the growing season. The results showed that the canopy openness increased with the increase of thinning intensities. PPFD and soil temperature and soil moisture content in different soil layers were positively relative with canopy openness after thinning. The richness of regenerating tree species did not significantly increase (p=0.30) after one growing season since thinning, but the regeneration density and frequency of tree species increased significantly (p〈0.05). In addition, the number of regenerating tree species increased, and the increment was correlated with the characteristics of iudividual tree species. The increasing percentage of regenerating seedlings of the shade-intolerant tree species was more than that of shade-tolerant tree species. Among the investigated regeneration species, the biggest response of seedling emergency to the canopy openness was Phellodendron amurense. This paper confirmed the following conclusions: after thinning, the variety of regenerating tree species was correlative with the characteristics of regenerating tree species, and the distribution of unthinned trees and the site conditions in the investigated larch plantation were the additional factors influencing, the regeneration.
基金financial support from the National Science and Technology Support Program of China(No.2015BAB18B00)。
文摘A two-stage oxidation—alkali leaching—acid leaching method was proposed to recovery Fe,V,and Ti in modified Ti-bearing blast furnace slag.The optimal experiment conditions of iron extraction were one-stage oxidation time 40 s and holding time 8 min.The recovery rate of iron was 89.93%.The optimum experiment conditions of vanadium extraction were total oxidation time of 126 s,NaOH concentration of 4.0 mol/L,leaching temperature of 95℃,leaching time of 90 min,and the number of cycle was 4.The leaching rate of vanadium was 92.13%.The optimal experiment conditions of titanium extraction were HCl concentration of 4.5 mol/L,leaching temperature of 75℃,and leaching time of 90 min.The TiO_(2)content of synthetic rutile was 98.61%.
基金Project supported by the Science Foundation (No. 2003C23015) and the Natural Science Foundation (No. Y204139) of Zhejiang Province, China
文摘This study is aimed at investigating the potentials of ex vivo expansion and pluri-differentiation of cryopreservation of adult human bone marrow mesenchymal stem cells (hMSCs) into chondrocytes, adipocytes and neurocytes. Cryopreserved hMSCs were resuscitated and cultured for 15 passages, and then induced into chondrocytes, adipocytes and neurocytes with corresponding induction medium. The induced cells were observed for morphological properties and detected for expressions of type II collagen, triglyceride or neuron-specific enolase and nestin. The result showed that the resuscitated cells could differentiate into chondrocytes after exposure to transforming growth factor 61 (TGF-~0, insulin-like growth factor I (IGF-I) and vitamin C (Vc), and uniformly changed morphologically from a spindle-like fibroblastic appearance to a polygonal shape in three weeks. The induced cells were heterochromatic to safranin O and expressed cartilage matrix-procollagenal (If) mRNA. The resuscitated cells cultured in induction medium consisting of dexamethasone, 3-isobutyl-l-methylxanthine, indomethacin and IGF-I showed adipogenesis, and lipid vacuoles accumulation was detectable after 21 d. The resuscitated hMSCs were also induced into neurocytes and expressed nestin and neuron specific endolase (NSE) that were special surface markers associated with neural cells at different stage. This study suggested that the resuscitated hMSCs should be still a population ofpluripotential cells and that it could be used for establishing an abundant bMSC reservoir for further experiment and treatment of various clinical discases.
基金National 973 Project No.2002CB412507+5 种基金 National Natural Science Foundation of China No.90202002 Knowledge Innovation Project of IGSNRR CAS No.CXIOG-E01-02-04 One Hundred Talents Program of CAS.
文摘Combined with recent historical climate data and two periods of land use datasets from remote sensing data, we test the net primary productivity (NPP) data sets in North Chinamodelled by the satellite data-driven Global Production Efficiency Model (GLO-PEM) for detecting thewidespread spatial and temporal characteristics of the impacts of climate and land use change onthe regional NPP. Our results show that over the past 20 years, the mean annual temperature in thestudy region has remarkably increased by more than 0.064 ℃, but over the same period, there hasbeen a 1.49 mm decrease in annual precipitation and decrease in NPP by an annual rate of 6.9 TgC.The NPP changes in the study region were greatly affected by the average temperature andprecipitation by ten-day periods as well as the seasonal temperature and precipitation in the studyregion. The correlation between seasonal NPP and seasonal precipitation and temperature is highlyconsistent with land cover spatially, and the correlation coefficient changes with the changes ofvegetation types. The analysis reveals that the related areas in land use change only take up 5.45%of the whole studied region, so the climate changes dominate the impacts on the NPP in the wholestudy region (90% of the total). However, land use plays an absolute dominative role in areas withland cover changes, accounting for 97% of the total. From 1981 to 2000, the NPP in the whole studyregion remarkably reduced due to obvious precipitation decrease and temperature rise. Between twoperiods of land use (about 10 years), the changes in climate are predicted to promote a decrease inNPP by 78 ( + -0.6) TgC, and integrated impacts of climate changes and land use to promote adecrease in NPP by 87(+-0.8) TgC.
文摘The land desertification in Xinjiang was monitored and analyzed based on RS and GIS techniques. Satellite data interpretation was adopted to obtain the general situation of Xinjiang’s land desertification in assistance with the sampling method and on-the-spot investigations. Related monitoring and investigations showed that Xinjiang was facing with severe wide range land desertification, and its desertified area made up 77.08% of the total monitoring area. As for land types, the desertified farmland accounted for 1.92% of the total monitoring area, desertified woodland 4%, desertified grassland 45%, and unused land 49%. Accordingly, as for desertification degrees, non-desertified land occupied 22.92%, weak desertified land 5.69%, medium-degree desertified land 16.58%, severe desertified land 33.19% and super severe desertified land 21.61%. Finally, as for inducing factors, wind-eroded desertification made up 58.23%, water-eroded desertification 8.69%, salinization desertification 6.52% and frozen-melt eroded desertification 3.64%. Xinjiang’s land desertification tended to get worse and the harnessing mission remained hard.
基金Projects(61573380,61303185) supported by the National Natural Science Foundation of ChinaProjects(2016M592450,2017M612585) supported by the China Postdoctoral Science FoundationProjects(2016JJ4119,2017JJ3416) supported by the Hunan Provincial Natural Science Foundation of China
文摘It is easy for teenagers to view pornographic pictures on social networks. Many researchers have studied the detection of real pornographic pictures, but there are few studies on those that are artificial. In this work, we studied how to detect artificial pornographic pictures, especially when they are on social networks. The whole detection process can be divided into two stages: feature selection and picture detection. In the feature selection stage, seven types of features that favour picture detection were selected. In the picture detection stage, three steps were included. 1) In order to alleviate the imbalance in the number of artificial pornographic pictures and normal ones, the training dataset of artificial pornographic pictures was expanded. Therefore, the features which were extracted from the training dataset can also be expanded too. 2) In order to reduce the time of feature extraction, a fast method which extracted features based on the proportionally scaled picture rather than the original one was proposed. 3) Three tree models were compared and a gradient boost decision tree (GBDT) was selected for the final picture detection. Three sets of experimental results show that the proposed method can achieve better recognition precision and drastically reduce the time cost of the method.
文摘An artificial neural network is used to predict the performance of fabrics in clothing manufacturing. The predictions are based on fabric mechanical properties measured on the FAST system. The influences of the different ANNs construct on the convergence speed and the prediction accuracy are investigated. The result indicates that the BP neural network is an efficiency technique and has a wide prospect in the application to garment processing.
基金funds from MIUR 2005 (Italian Ministry for University and Research) and University Sapienza Roma
文摘AIM: To investigate the role of artifi cial neural networks in predicting the presence of thyroid disease in atrophic body gastritis patients. METHODS: A dataset of 29 input variables of 253 atrophic body gastritis patients was applied to artifi cial neural networks (ANNs) using a data optimisation procedure (standard ANNs,T&T-IS protocol,TWIST protocol). The target variable was the presence of thyroid disease. RESULTS: Standard ANNs obtained a mean accuracy of 64.4% with a sensitivity of 69% and a specifi city of 59.8% in recognizing atrophic body gastritis patients with thyroid disease. The optimization procedures (T&T-IS and TWIST protocol) improved the performance of the recognition task yielding a mean accuracy,sensitivity and specifi city of 74.7% and 75.8%,78.8% and 81.8%,and 70.5% and 69.9%,respectively. The increase of sensitivity of the TWIST protocol was statistically signifi cant compared to T&T-IS. CONCLUSION: This study suggests that artificial neural networks may be taken into consideration as a potential clinical decision-support tool for identifying ABG patients at risk for harbouring an unknown thyroid disease and thus requiring diagnostic work-up of their thyroid status.
文摘With the rapid development of space technology,earth observation tech nology and sky observatory technolo-gy,they have played a more and more im portant part in monitoring and predi cting of earthquakes and volcanoes i n the terres-trial land.In recent years,the rela ted agencies have done the experimen ts and researches on monitoring and p redicting of earthquakes and volcanoes in the forewarning period by means of many appr oaches,such as satellite thermal in frared re-mote sensing(TIRS),Global Positioning System(GPS),differential interferometric syn thesis aperture radar(D-INSAR),astronomical time-latitude residual anomaly,and Geographic Information Systems (GIS),etc.A quite large number of re-search foundation has been built in t he fundamental theories and applica tion methods.The experiments and re searches have shown that these technology is e fficient methods for high frequency crust movement.If the existed separate scientific forces and results are possibly asse mbled together to form a more complete integration monitoring system wit h the combina-tion of space,sky observation,grou nd,deep geology and macro anomaly,i t will come into a new stage of monitoring and predicting of earthquakes and volca nic eruptions.