Three antagonistic yeasts, Trichosporon pullulans (Lindner.) Diddens and Lodder, Cryptococcus laurentii (Kuffer.) Skinner and Rhodotorula glutinis (Fresen.) F. C. Harrison, selected from over 50 yeasts on apple fruits...Three antagonistic yeasts, Trichosporon pullulans (Lindner.) Diddens and Lodder, Cryptococcus laurentii (Kuffer.) Skinner and Rhodotorula glutinis (Fresen.) F. C. Harrison, selected from over 50 yeasts on apple fruits, were investigated of their biocontrol efficacy against blue mould rot caused by Penicillium expansum Link in apple fruits. T. pullulans was identified to be a new yeast antagonist and was the most effective at inhibiting blue mould rot in the three yeasts. The effects of different concentrations of the three yeasts and addition Of nutrients, as well as combination with calcium on controlling blue mould rot in apples were presented in the paper. The results indicated that the higher the yeast concentrations, the more effective the yeasts on biocontrol activity. Addition of nutrients reduced the biocontrol capacity of the yeasts. Combination of 0.18 mol/L CaCl2 with C. laurentii cell suspensions could significantly enhance its effect to P. expansum in apple fruits, while the efficacy of calcium on biocontrol activity of T. pullulans or R. glutinis was not remarkable.展开更多
A new natural product (1) together with 26 know compounds were isolated from the Bulbs of Ornithogalum caudatum. Their structures were established on the basis of spectral analyses as n-butyl pyroglutamate (1), nonade...A new natural product (1) together with 26 know compounds were isolated from the Bulbs of Ornithogalum caudatum. Their structures were established on the basis of spectral analyses as n-butyl pyroglutamate (1), nonadecyl alcohol(2), eicosanol(3), behenic acid(4), b-sitosterol(5), stigmasterol(6), glycerol 1-monocerotate(7), pyrocatechol(8), p-ethoxybenzoic acid(9), p-coumarinic acid(10), protocatechuric acid(11), ursolic acid(12), betulinic acid(13), fumaric acid(14), succinic acid(15), uracil(16), xanthine(17), quercetin(18), kaempferol (19), isorham-netin(20), adenosine(21), daucosterol(22), stigmasterol 3-O-b-D-glucopyranoside(23), quercetin 3-O-b-D-glucopyra-noside(24), kaempferol 3-O-b-D-glucopyranoside(25), rutin(26), and kaempferol 3-O-b-rutinoside(27). All of them, except compound 5, were isolated from this plant for the first time.展开更多
Based on the analysis of the main failures discovered in pavement on steel deck plate and the demanding service condition of the pavement on steel deck, high-temperature rutting test, low-temperature bending test and ...Based on the analysis of the main failures discovered in pavement on steel deck plate and the demanding service condition of the pavement on steel deck, high-temperature rutting test, low-temperature bending test and controlled stress flexural fatigue test are used to study the performance of asphalt mixtures modified by epoxy resin including high-temperature stability, low-temperature cracking-resistance, and fatigue cracking-resistance, which are served to evaluate the modification effect of epoxy resin of different contents. With the addition of epoxy resin, all the three performances are improved greatly. However, when the amount of epoxy resin added is over a certain value, the modification effect will be stable with no extra benefit detected. Finally, in terms of the properties of the three respects, 20%, 30%, 30% are given separately as the proposal adding contents.展开更多
Effect of salinity on survival,feeding behavior and growth of juvenile swimming crab P ortunus trituberculatus was investigated under 5 salinity levels of 5,10,20,30 and 40. The results show that the crab juveniles fe...Effect of salinity on survival,feeding behavior and growth of juvenile swimming crab P ortunus trituberculatus was investigated under 5 salinity levels of 5,10,20,30 and 40. The results show that the crab juveniles fed 2 or 3 times at the salinity 20 and 30,each lasted for about 25 minutes,for a total feeding time of 73.2±22.65 minutes per day. At these salinities,there were significantly higher in the frequency of feeding and in total feeding time than those at lower salinities of 5 and 10. All crab juveniles moulted when reared at a salinity of 20 during the 5 days duration of the experiment,which is significantly higher than those at other salinities. All juveniles survived at salinity 20,and the survivorship was not significantly different from that at 30,but was signif icantly higher than those at other salinities. The crab juveniles reared at a salinity of 20 had the highest value of food ration of 0.190 8±0.011 3 g/g BW,average body weight gain of 0.796±0.128 g,gain rate of 87%–96%,and food conversion ratio of 1.20±0.09. There was no significant difference in the values found between 20 and 30 but these values were significantly lower than that at the other salinities( P> 0.05). Highest activities of digestive enzymes(Amylase,Protease,Lipase) and lowest activities of protective enzymes(SOD,PO,CAT) were also obtained on crab juveniles reared at salinity of 20.展开更多
The research explored growth and development, economic profits, and eco- logical benefits of released black carps on basis of 21 group ecological data on 52 365 fish within 6 months. The results indicated that the age...The research explored growth and development, economic profits, and eco- logical benefits of released black carps on basis of 21 group ecological data on 52 365 fish within 6 months. The results indicated that the age and growth index of released black carp were normal and body length and size were coordinated; 88.89% released black carps exceeded theoretical weight, with an average of 25.15%, which indicated that black carps are hardly to reproduct naturally. In 2013, 310 000 black carps were released in the Reservoir, and 123 tons black carps were obtained, with direct economic value of 2.46 million yuan and indirect econom- ic value of 3.84 million yuan. It can be concluded based on averages that 123 tons black carps can be produced in 2013 and 3 690 kg nitrogen and 740 kg phospho- rus can be removed. The releasing of fish has shown much more economic, ecological and social benefits in Yantan Reservoir, but the hidden dangers still exist on fishery environment. Therefore, it is necessary to further increase the number of re- leased black carps in the Reservoir.展开更多
The effects of frozen storage at -18 ℃ up to 6 months, on the antioxidant properties, chemical composition and other physicochemical properties of myrtle berries (Myrtus comrnunis L.) has been evaluated. Berries sh...The effects of frozen storage at -18 ℃ up to 6 months, on the antioxidant properties, chemical composition and other physicochemical properties of myrtle berries (Myrtus comrnunis L.) has been evaluated. Berries showed a good resistance to storage decay, and weight loss remained after six months in the 15% range. Results showed that frozen storage up to 6 months affect individual antocyanins content in different ways. Nevertheless the total anthocyanins content was at the end of storage higher than in fresh fruits. The antioxidant capacity calculated with 2,2-diphenyl-l-picrylhidrazyl (DPPH) and 2,2'-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) increased during storage and the calculated r2 showed a positive correlation with the total anthocyanins content. Gluconic and fumaric acid did not changed, quinic acid decreased while malic and shikimic acid increased. The total organic acid content during storage was higher than in fresh fruits causing a slight decrease in pH. Fructose and glucose increased with the same rate and the ratio fructose/glucose remained unchanged (1.06 ± 0.01), CIE L^*a^*b^* coordinates showed a shift of the colour to tawny brown after six months storage.展开更多
Traditional thermal methods of drying food have often led to loss of flavours, nutrients, vitamins, etc., which encourages non-thermal pretreatments such as osmotic dehydration (OD) and/or high electric field (HEF...Traditional thermal methods of drying food have often led to loss of flavours, nutrients, vitamins, etc., which encourages non-thermal pretreatments such as osmotic dehydration (OD) and/or high electric field (HEF) application to improve the overall product quality. The aim of this study was to evaluate the effect of osmotic dehydration (50% sucrose) with high electric field strengths of 0.5 and 1.0 kV/cm as pretreatments on the drying kinetics and mass transfer of green apples during convective drying at 65 ~C and microwave drying at 1 W/g. The added value of the OD and HEF on the drying kinetics, and the effective mass transfer coefficients of the subsequent drying methods were investigated through this research. The efficacy of these pre-treatments was assessed and compared using cell disintegration index, product texture and thus bring forth new correlations between these pre-treatments and the cell disintegration index using dielectric spectroscopy and its effect on the product texture.展开更多
Peripheral primitive neuroectodermal tumor(pPNET) is an extremely rare disease entity of malignant tumors belonging to the Ewing sarcoma family that usually occurs in children and adolescents. We describe a 41-year-ol...Peripheral primitive neuroectodermal tumor(pPNET) is an extremely rare disease entity of malignant tumors belonging to the Ewing sarcoma family that usually occurs in children and adolescents. We describe a 41-year-old female who presented with right upper abdominal pain. Surgical resection and biopsy revealed small round-cell tumor. Combined with immunohistochemical analysis, pPNET was diagnosed. No evidence of recurrence was noted at 18 months postoperatively. Even thought pPNET is a highly malignant tumor, Wide tumor-free resection and multi-agent chemotherapy can also obtain good clinical outcomes.展开更多
The structural design of asphalt foaming device, the determination of foam chamber process and condition parameters are the key technologies to foaming effect of foam asphalt. In this paper, we analyze the research st...The structural design of asphalt foaming device, the determination of foam chamber process and condition parameters are the key technologies to foaming effect of foam asphalt. In this paper, we analyze the research status of foaming mechanism, foaming device design and determination of the various parameters. The paper puts forward opinions for asphalt foaming technology. And development trend of the asphalt foaming technology is analyzed.展开更多
In order to validate the control effects of integrated technology of medicine and fertilizer on tobacco bacterial wilt,field experiments were conducted by using youmeili and tetracycline as the test agents.The results...In order to validate the control effects of integrated technology of medicine and fertilizer on tobacco bacterial wilt,field experiments were conducted by using youmeili and tetracycline as the test agents.The results obtained were listed as follows:(1)The incidence rate of bacterial wilt ascended more quickly after July 10 th,the incidence of CK reached 78.30%on July 25 th.(2)The control effect of“youmeili 3 g+tetramycin 200 times liquid”reached 69.47%,significantly higher than other treatments.(3)The output value of“Youmeil 3 g+tetramycin 200 times liquid”served as 1635.66 yuan/667m^2,with the highest economic character in all treatments.In a word,integrated technology of medicine and fertilizer was a feasible approach to control tobacco bacterial wilt.展开更多
Objective To evaluate the predictive factors of refractory glaucoma treated with diode laser transscleral cyclophotocoagulation(TSCP) in a midterm observation.Methods Fifty-four consecutive patients(54 eyes) with refr...Objective To evaluate the predictive factors of refractory glaucoma treated with diode laser transscleral cyclophotocoagulation(TSCP) in a midterm observation.Methods Fifty-four consecutive patients(54 eyes) with refractory glaucoma were enrolled and underwent TSCP(power of 1.5-2.0 W,exposure time of 2 seconds and 20-50 applications).Patients were regularly followed up for 12 months.Intraocular pressure(IOP) was measured before TSCP treatment and at each follow-up visit.Patients were divided into the sensitive and insensitive groups according to the effect of a single treatment of TSCP on IOP.The success rate was defined as the percentage of eyes achieving an IOP between 5 and 21 mm Hg following TSCP therapy at their final follow up visit.Difference of age between the sensitive and insensitive groups was evaluated with Independent-samples T test and that of gender distribution of two groups was evaluated with Fisher's exact test.The success rate of different types of glaucoma to TSCP was calculated.Results A total of 32 patients were sensitive to TSCP(sensitive group) and 22 patients were insensitive to TSCP(insensitive group).The success rates of female(77.8%,14/18) and cases being over 50 years(71.4%,20/28) were higher than those of male(50.0%,18/36) and ones being under 50 years(46.2%,12/26)(all P>0.05).The age of the sensitive and insensitive groups was 56.0±15.5 and 46.4±15.4 years,respectively(P=0.029).The age(P=0.029) and gender distribution(P=0.046) of the two groups had significant difference.The success rate of neovascular glaucoma,primary angle-closure glaucoma,primary open angle glaucoma,traumatic glaucoma,uveitic glaucoma,and secondary glaucoma after silicone oil injection to TSCP was 57.1%,100.0%,50.0%,20.0%,81.8%,and 0%,respectively.Conclusion Age,gender,and type of glaucoma appear to be associated with effect of TSCP on IOP control.展开更多
Background Atherosclerotic plaques indicate the occurrence of ischemia events and it is a difficult task for clinical physicians. Grape seed proanthocyanidin extract (GSPE) has been reported to exert an antiatheroge...Background Atherosclerotic plaques indicate the occurrence of ischemia events and it is a difficult task for clinical physicians. Grape seed proanthocyanidin extract (GSPE) has been reported to exert an antiatherogenic effect by inducing regression of atherosclerotic plaques in animal experimental studies. In this study, the antiatherogenic effect of GSPE has been investigated in clinical use. Methods Consecu- tive 287 patients diagnosed with asymptomatic carotid plaques or abnormal plaque free carotid intima-media thickness (CIMT) were ran- domly assigned to the GSPE group (n = 146) or control group (n = 141). The patients in the GSPE group received GSPE 200 mg per day orally, while patients in the control group were only enrolled in a lifestyle intervention program. Carotid ultrasound examination was per- formed at baseline and 6, 12, 24 months during follow-up. Mean maximum CIMT (MMCIMT), plaque score, echogenicity of plaques and ischemic vascular events were recorded. Results As anticipated, after treatment, GSPE resulted in significant reduction in MMCIMT pro- gression (4.2% decrease after six months, 4.9% decrease after 12 months and 5.8% decrease after 24 months) and plaque score (10.9% de- crease after six months, 24.1% decrease after 12 months and 33.1% decrease after 24 months) for the primary outcome, while MMCIMT and plaque score were stable and even increased with the time going on in control group. The number of plaques and unstable plaques also de- creased after treatment of GSPE. Furthermore, the carotid plaque can disappear after treatment with GSPE. The incidence rate for transitory ischemic attack (TIA), arterial revascularization procedure, and hospital readmission for unstable angina in GSPE group were statistically significant lower (P = 0.02, 0.08, 0.002, respectively) compared with the control group. Conclusions GSPE inhibited the progression of MMCIMT and reduced carotid plaque size in GSPE treated patients, and with extended treatment, the superior efficacy on MMCIMT and carotid plaque occurred. Furthermore, the GSPE group showed lower rates of clinical vascular events.展开更多
In the oil sands industry, high temperature with the addition of a caustic dispersing agent has formed the basis of the Clark hot water extraction process used successfully on a commercial scale to recover bitumen fro...In the oil sands industry, high temperature with the addition of a caustic dispersing agent has formed the basis of the Clark hot water extraction process used successfully on a commercial scale to recover bitumen from surface mined oil sands ore since 1967. Processes different from the established Clark process (high temperature and caustic) have been developed to work at a range of temperatures with or without the use of sodium hydroxide. Large scale bitumen extraction pilot tests were performed with two different extraction processes and large strain consolidation tests were performed on the resulting different railings. These consolidation tests determined the compressibility and hydraulic conductivity relationships with void ratio which are engineering properties that influence the long-term disposal of the fine tailings. They were used in large strain consolidation numerical analyses of storage ponds to predict water release rates and changes to surface elevations that impact storage volumes and elevation of reclamation surfaces.展开更多
文摘Three antagonistic yeasts, Trichosporon pullulans (Lindner.) Diddens and Lodder, Cryptococcus laurentii (Kuffer.) Skinner and Rhodotorula glutinis (Fresen.) F. C. Harrison, selected from over 50 yeasts on apple fruits, were investigated of their biocontrol efficacy against blue mould rot caused by Penicillium expansum Link in apple fruits. T. pullulans was identified to be a new yeast antagonist and was the most effective at inhibiting blue mould rot in the three yeasts. The effects of different concentrations of the three yeasts and addition Of nutrients, as well as combination with calcium on controlling blue mould rot in apples were presented in the paper. The results indicated that the higher the yeast concentrations, the more effective the yeasts on biocontrol activity. Addition of nutrients reduced the biocontrol capacity of the yeasts. Combination of 0.18 mol/L CaCl2 with C. laurentii cell suspensions could significantly enhance its effect to P. expansum in apple fruits, while the efficacy of calcium on biocontrol activity of T. pullulans or R. glutinis was not remarkable.
基金This work was supported by the Ministry of Science and Technology of China (96-901-05-266).
文摘A new natural product (1) together with 26 know compounds were isolated from the Bulbs of Ornithogalum caudatum. Their structures were established on the basis of spectral analyses as n-butyl pyroglutamate (1), nonadecyl alcohol(2), eicosanol(3), behenic acid(4), b-sitosterol(5), stigmasterol(6), glycerol 1-monocerotate(7), pyrocatechol(8), p-ethoxybenzoic acid(9), p-coumarinic acid(10), protocatechuric acid(11), ursolic acid(12), betulinic acid(13), fumaric acid(14), succinic acid(15), uracil(16), xanthine(17), quercetin(18), kaempferol (19), isorham-netin(20), adenosine(21), daucosterol(22), stigmasterol 3-O-b-D-glucopyranoside(23), quercetin 3-O-b-D-glucopyra-noside(24), kaempferol 3-O-b-D-glucopyranoside(25), rutin(26), and kaempferol 3-O-b-rutinoside(27). All of them, except compound 5, were isolated from this plant for the first time.
文摘Based on the analysis of the main failures discovered in pavement on steel deck plate and the demanding service condition of the pavement on steel deck, high-temperature rutting test, low-temperature bending test and controlled stress flexural fatigue test are used to study the performance of asphalt mixtures modified by epoxy resin including high-temperature stability, low-temperature cracking-resistance, and fatigue cracking-resistance, which are served to evaluate the modification effect of epoxy resin of different contents. With the addition of epoxy resin, all the three performances are improved greatly. However, when the amount of epoxy resin added is over a certain value, the modification effect will be stable with no extra benefit detected. Finally, in terms of the properties of the three respects, 20%, 30%, 30% are given separately as the proposal adding contents.
基金Supported by the Science and Technology Innovation Team of Marine Crab Industry in Ningbo City(No.2011B81003)the National Natural Science Foundation of China(No.41276123)+2 种基金the National Spark Plan Program of China(No.2012GA701048)the Key Project of Ministry of Education,Science and Technology(No.212070)the K C Wong Magana Fund in Ningbo University
文摘Effect of salinity on survival,feeding behavior and growth of juvenile swimming crab P ortunus trituberculatus was investigated under 5 salinity levels of 5,10,20,30 and 40. The results show that the crab juveniles fed 2 or 3 times at the salinity 20 and 30,each lasted for about 25 minutes,for a total feeding time of 73.2±22.65 minutes per day. At these salinities,there were significantly higher in the frequency of feeding and in total feeding time than those at lower salinities of 5 and 10. All crab juveniles moulted when reared at a salinity of 20 during the 5 days duration of the experiment,which is significantly higher than those at other salinities. All juveniles survived at salinity 20,and the survivorship was not significantly different from that at 30,but was signif icantly higher than those at other salinities. The crab juveniles reared at a salinity of 20 had the highest value of food ration of 0.190 8±0.011 3 g/g BW,average body weight gain of 0.796±0.128 g,gain rate of 87%–96%,and food conversion ratio of 1.20±0.09. There was no significant difference in the values found between 20 and 30 but these values were significantly lower than that at the other salinities( P> 0.05). Highest activities of digestive enzymes(Amylase,Protease,Lipase) and lowest activities of protective enzymes(SOD,PO,CAT) were also obtained on crab juveniles reared at salinity of 20.
基金Supported by Guangxi Natural Science Foundation(2013GXNSFEA053003)Special Fund for Agro-scientific Research in the Public Interest(201303048)Germplasm Resource Protection Project of Ministry of Agriculture([2013]75)~~
文摘The research explored growth and development, economic profits, and eco- logical benefits of released black carps on basis of 21 group ecological data on 52 365 fish within 6 months. The results indicated that the age and growth index of released black carp were normal and body length and size were coordinated; 88.89% released black carps exceeded theoretical weight, with an average of 25.15%, which indicated that black carps are hardly to reproduct naturally. In 2013, 310 000 black carps were released in the Reservoir, and 123 tons black carps were obtained, with direct economic value of 2.46 million yuan and indirect econom- ic value of 3.84 million yuan. It can be concluded based on averages that 123 tons black carps can be produced in 2013 and 3 690 kg nitrogen and 740 kg phospho- rus can be removed. The releasing of fish has shown much more economic, ecological and social benefits in Yantan Reservoir, but the hidden dangers still exist on fishery environment. Therefore, it is necessary to further increase the number of re- leased black carps in the Reservoir.
文摘The effects of frozen storage at -18 ℃ up to 6 months, on the antioxidant properties, chemical composition and other physicochemical properties of myrtle berries (Myrtus comrnunis L.) has been evaluated. Berries showed a good resistance to storage decay, and weight loss remained after six months in the 15% range. Results showed that frozen storage up to 6 months affect individual antocyanins content in different ways. Nevertheless the total anthocyanins content was at the end of storage higher than in fresh fruits. The antioxidant capacity calculated with 2,2-diphenyl-l-picrylhidrazyl (DPPH) and 2,2'-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) increased during storage and the calculated r2 showed a positive correlation with the total anthocyanins content. Gluconic and fumaric acid did not changed, quinic acid decreased while malic and shikimic acid increased. The total organic acid content during storage was higher than in fresh fruits causing a slight decrease in pH. Fructose and glucose increased with the same rate and the ratio fructose/glucose remained unchanged (1.06 ± 0.01), CIE L^*a^*b^* coordinates showed a shift of the colour to tawny brown after six months storage.
文摘Traditional thermal methods of drying food have often led to loss of flavours, nutrients, vitamins, etc., which encourages non-thermal pretreatments such as osmotic dehydration (OD) and/or high electric field (HEF) application to improve the overall product quality. The aim of this study was to evaluate the effect of osmotic dehydration (50% sucrose) with high electric field strengths of 0.5 and 1.0 kV/cm as pretreatments on the drying kinetics and mass transfer of green apples during convective drying at 65 ~C and microwave drying at 1 W/g. The added value of the OD and HEF on the drying kinetics, and the effective mass transfer coefficients of the subsequent drying methods were investigated through this research. The efficacy of these pre-treatments was assessed and compared using cell disintegration index, product texture and thus bring forth new correlations between these pre-treatments and the cell disintegration index using dielectric spectroscopy and its effect on the product texture.
文摘Peripheral primitive neuroectodermal tumor(pPNET) is an extremely rare disease entity of malignant tumors belonging to the Ewing sarcoma family that usually occurs in children and adolescents. We describe a 41-year-old female who presented with right upper abdominal pain. Surgical resection and biopsy revealed small round-cell tumor. Combined with immunohistochemical analysis, pPNET was diagnosed. No evidence of recurrence was noted at 18 months postoperatively. Even thought pPNET is a highly malignant tumor, Wide tumor-free resection and multi-agent chemotherapy can also obtain good clinical outcomes.
基金Foundation of Xi'an Science Plan(CX12180(4))the Special Fund for Basic Scientific Research of Central Colleges of Chang’an University(CHD2010JC092)
文摘The structural design of asphalt foaming device, the determination of foam chamber process and condition parameters are the key technologies to foaming effect of foam asphalt. In this paper, we analyze the research status of foaming mechanism, foaming device design and determination of the various parameters. The paper puts forward opinions for asphalt foaming technology. And development trend of the asphalt foaming technology is analyzed.
基金Supported by Science and Technology Project of Yunnan Tobacco Company(2015YN07,2017YN26)~~
文摘In order to validate the control effects of integrated technology of medicine and fertilizer on tobacco bacterial wilt,field experiments were conducted by using youmeili and tetracycline as the test agents.The results obtained were listed as follows:(1)The incidence rate of bacterial wilt ascended more quickly after July 10 th,the incidence of CK reached 78.30%on July 25 th.(2)The control effect of“youmeili 3 g+tetramycin 200 times liquid”reached 69.47%,significantly higher than other treatments.(3)The output value of“Youmeil 3 g+tetramycin 200 times liquid”served as 1635.66 yuan/667m^2,with the highest economic character in all treatments.In a word,integrated technology of medicine and fertilizer was a feasible approach to control tobacco bacterial wilt.
文摘Objective To evaluate the predictive factors of refractory glaucoma treated with diode laser transscleral cyclophotocoagulation(TSCP) in a midterm observation.Methods Fifty-four consecutive patients(54 eyes) with refractory glaucoma were enrolled and underwent TSCP(power of 1.5-2.0 W,exposure time of 2 seconds and 20-50 applications).Patients were regularly followed up for 12 months.Intraocular pressure(IOP) was measured before TSCP treatment and at each follow-up visit.Patients were divided into the sensitive and insensitive groups according to the effect of a single treatment of TSCP on IOP.The success rate was defined as the percentage of eyes achieving an IOP between 5 and 21 mm Hg following TSCP therapy at their final follow up visit.Difference of age between the sensitive and insensitive groups was evaluated with Independent-samples T test and that of gender distribution of two groups was evaluated with Fisher's exact test.The success rate of different types of glaucoma to TSCP was calculated.Results A total of 32 patients were sensitive to TSCP(sensitive group) and 22 patients were insensitive to TSCP(insensitive group).The success rates of female(77.8%,14/18) and cases being over 50 years(71.4%,20/28) were higher than those of male(50.0%,18/36) and ones being under 50 years(46.2%,12/26)(all P>0.05).The age of the sensitive and insensitive groups was 56.0±15.5 and 46.4±15.4 years,respectively(P=0.029).The age(P=0.029) and gender distribution(P=0.046) of the two groups had significant difference.The success rate of neovascular glaucoma,primary angle-closure glaucoma,primary open angle glaucoma,traumatic glaucoma,uveitic glaucoma,and secondary glaucoma after silicone oil injection to TSCP was 57.1%,100.0%,50.0%,20.0%,81.8%,and 0%,respectively.Conclusion Age,gender,and type of glaucoma appear to be associated with effect of TSCP on IOP control.
文摘Background Atherosclerotic plaques indicate the occurrence of ischemia events and it is a difficult task for clinical physicians. Grape seed proanthocyanidin extract (GSPE) has been reported to exert an antiatherogenic effect by inducing regression of atherosclerotic plaques in animal experimental studies. In this study, the antiatherogenic effect of GSPE has been investigated in clinical use. Methods Consecu- tive 287 patients diagnosed with asymptomatic carotid plaques or abnormal plaque free carotid intima-media thickness (CIMT) were ran- domly assigned to the GSPE group (n = 146) or control group (n = 141). The patients in the GSPE group received GSPE 200 mg per day orally, while patients in the control group were only enrolled in a lifestyle intervention program. Carotid ultrasound examination was per- formed at baseline and 6, 12, 24 months during follow-up. Mean maximum CIMT (MMCIMT), plaque score, echogenicity of plaques and ischemic vascular events were recorded. Results As anticipated, after treatment, GSPE resulted in significant reduction in MMCIMT pro- gression (4.2% decrease after six months, 4.9% decrease after 12 months and 5.8% decrease after 24 months) and plaque score (10.9% de- crease after six months, 24.1% decrease after 12 months and 33.1% decrease after 24 months) for the primary outcome, while MMCIMT and plaque score were stable and even increased with the time going on in control group. The number of plaques and unstable plaques also de- creased after treatment of GSPE. Furthermore, the carotid plaque can disappear after treatment with GSPE. The incidence rate for transitory ischemic attack (TIA), arterial revascularization procedure, and hospital readmission for unstable angina in GSPE group were statistically significant lower (P = 0.02, 0.08, 0.002, respectively) compared with the control group. Conclusions GSPE inhibited the progression of MMCIMT and reduced carotid plaque size in GSPE treated patients, and with extended treatment, the superior efficacy on MMCIMT and carotid plaque occurred. Furthermore, the GSPE group showed lower rates of clinical vascular events.
文摘In the oil sands industry, high temperature with the addition of a caustic dispersing agent has formed the basis of the Clark hot water extraction process used successfully on a commercial scale to recover bitumen from surface mined oil sands ore since 1967. Processes different from the established Clark process (high temperature and caustic) have been developed to work at a range of temperatures with or without the use of sodium hydroxide. Large scale bitumen extraction pilot tests were performed with two different extraction processes and large strain consolidation tests were performed on the resulting different railings. These consolidation tests determined the compressibility and hydraulic conductivity relationships with void ratio which are engineering properties that influence the long-term disposal of the fine tailings. They were used in large strain consolidation numerical analyses of storage ponds to predict water release rates and changes to surface elevations that impact storage volumes and elevation of reclamation surfaces.