基于JB和B/S模式OA系统的设计与实现

基于JB和B/S模式开发的OA系统,采用三层Web应用体系结构的模块设计方法,借助JavaBean组件技术、JDBC接口技术来实现。文中介绍了系统的设计与实现过程,提供了公文管理JavaBean组件技术的关键代码,解决了系统实现中中文乱码等几个问题。

Real-Time Information System of Power Plant Based on B/S Computing Mode

This paper introduces the system structure and work principle of the upgraded real time information system in Wangting Power Plant, and then expounds the realization way and function features of this system on B/S computing mode. The results of field application show the new system has good capability, reliability and expandability.

Hepatitis B virus upregulates host expression of α-1,2-mannosidases via the PPARα pathway

AIM To assess the effects of hepatitis B virus(HBV) on the expression of host α-1,2-mannosidases and determine the underlying mechanisms.METHODS We measured the expression levels of MAN1A1, MAN1A2, MAN1B1, and MAN1C1 in cell lines HepG 2.2.15, HepN 10, HepA D38 and Hep G2 by Western blot. Viral antigens(HBs Ag and HBe Ag) in the culture medium were measured using the chemiluminescence method. HBV DNA quantification assays were performed using a commercial real-time PCR kit. Protein levels of human liver tissue α-1,2-mannosidases were also evaluated by Western blot. Plasmids containing seven individual viral genes of HBV(PTT22-HBx, PTT22-HBs, PTT22-pre S2, PTT22-pre S1, PTT22-HBc, PTT22-HBe, and PTT22-HBp) or control plasmids(PTT22-vector) were transfected into Hep G2 cells. MK886(PPARα) and GW9662(PPARγ) inhibitors were used to explore the effects of HBV on α-1,2-mannosidase expression after the PPARα and PPARγ pathways were blocked.RESULTS We showed that the expression of α-1,2-mannosidases was higher in stably transfected HBV cells than in controls. The expression levels of α-1,2-mannosidase were higher in AD38 cells than those in ND10 cells, which were in turn greater than those in G2.2.15 cells, and positively correlated with the expression of HBsA gin all the cell lines. Levels of α-1,2-mannosidase in nontumorous liver tissues of HBV-related HCC patients were also higher than in the tissues from non-HBVrelated HCC patients. Moreover, transfecting Hep G2 cells with a component of the HBV viral envelope also increased the expression of α-1,2-mannosidases. However, this envelope protein component could not induce MAN1C1 expression in the presence of a PPARα inhibitor, MK886. We also found that MK886 did not affect the expression of MAN1C1 in AD38 cells without tetracycline in the culture medium. This phenomenon was not observed in the case of GW9662.CONCLUSION Our results indicate that HBV increases the expression of α-mannosidases both in vitro and in vivo via activation of the PPARα pathway by its envelope protein.

Application Analysis of multimedia technology in the B-learning pedagogy

With the rapid development of modern information technology, in order to meet requirements of the new situation and new technologies, today＇ s teaching model has undergone a qualitative change. New teaching model are an entirely new challenge for health professional colleges, the college teachers and students. The Once chalk teaching is replaced by multimedia teaching, which is gradually popular in the country, including schools, tertiary institutions. But in recent years we have gradually discovered the shortcomings of multimedia teaching and thereby created a new hybrid teaching model B-Learning teaching. Multimedia technology effectively combining with the B-learning teaching model, will remove multimedia technology weaknesses, and better play their strengths in teaching.

The gene expression patterns of BMPR2,EP300,TGFβ2,and TNFAIP3 in B-Lymphoma cells

Objective: The results of a previous study showed that a clear dysregulation was evident in the global gene expression of the BCL11A-suppressed B-lymphoma cells. In this study, the bone morphogenetic protein receptor, type II(BMPR2), E1 A binding protein p300(EP300), transforming growth factor-β2(TGFβ2), and tumor necrosis factor, and alpha-induced protein 3(TNFAIP3) gene expression patterns in B-cell malignancies were studied. Methods: The relative expression levels of BMPR2, EP300, TGFβ2, and TNFAIP3 mRNA in B-lymphoma cell lines, myeloid cell lines, as well as in cells from healthy volunteers, were determined by real-time quantitative reverse transcriptpolymerase chain reaction(qRT-PCR) with SYBR Green Dye. Glyceraldehyde-3-phosphate dehydrogenase(GAPDH) was used as reference. Results: The expression level of TGFβ2 mRNA in B-lymphoma cell lines was significantly higher than those in the cells from the healthy control(P<0.05). However, the expression level of TNFAIP3 mRNA in B-malignant cells was significantly lower than that of the healthy control(P<0.05). The expression levels of BMPR2 and EP300 mRNA showed no significant difference between B-malignant cell lines and the healthy group(P>0.05). In B-lymphoma cell lines, correlation analyses revealed that the expression of BMPR2 and TNFAIP3(r=0.882, P=0.04) had significant positive relation. The expression levels of BMPR2, EP300, and TNFAIP3 mRNA in cell lines from myeloid leukemia were significantly lower than those in the cells from the healthy control(P<0.05). The expression levels of TGFβ2 mRNA showed no significant difference between myeloid leukemia cell lines and the healthy control or B-malignant cell lines(P>0.05). The expression levels of BMPR2, EP300, and TNFAIP3 mRNA in B-lymphoma cells were significantly higher than those of the myeloid leukemia cells(P<0.05).Conclusion: Different expression patterns of BMPR2, EP300, TGFβ2, and TNFAIP3 genes in B-lymphoma cells exist.

穿越灾难时代的文明延续者

在好莱坞影片《世界末日》中，人类抵御流星来袭和拯救地球的努力过程惊心动魄。影星布鲁斯·威利饰演了一个守护孤女的强悍父亲，智慧过人的钻探专家和工头，还有携火星钻探机赴太空炸毁流星的英雄。现在，另一个美国人莱斯特·R·布朗，正在用一本名为《B模式》的书，向世人展现同样拯救地球的意向。

Classification of EEG-based single-trial motor imagery tasks using a B-CSP method for BCI

Classifying single-trial electroencephalogram(EEG)based motor imagery(MI)tasks is extensively used to control brain-computer interface(BCI)applications,as a communication bridge between humans and computers.However,the low signal-to-noise ratio and individual differences of EEG can affect the classification results negatively.In this paper,we propose an improved common spatial pattern(B-CSP)method to extract features for alleviating these adverse effects.First,for different subjects,the method of Bhattacharyya distance is used to select the optimal frequency band of each electrode including strong event-related desynchronization(ERD)and event-related synchronization(ERS)patterns;then the signals of the optimal frequency band are decomposed into spatial patterns,and the features that can describe the maximum differences of two classes of MI are extracted from the EEG data.The proposed method is applied to the public data set and experimental data set to extract features which are input into a back propagation neural network(BPNN)classifier to classify single-trial MI EEG.Another two conventional feature extraction methods,original common spatial pattern(CSP)and autoregressive(AR),are used for comparison.An improved classification performance for both data sets(public data set:91.25%±1.77%for left hand vs.foot and84.50%±5.42%for left hand vs.right hand;experimental data set:90.43%±4.26%for left hand vs.foot)verifies the advantages of the B-CSP method over conventional methods.The results demonstrate that our proposed B-CSP method can classify EEG-based MI tasks effectively,and this study provides practical and theoretical approaches to BCI applications.

A survey on the local refinable splines

This paper provides a survey of local refinable splines,including hierarchical B-splines,T-splines,polynomial splines over T-meshes,etc.,with a view to applications in geometric modeling and iso-geometric analysis.We will identify the strengths and weaknesses of these methods and also offer suggestions for their using in geometric modeling and iso-geometric analysis.

Precision of future experiments measuring primordial tensor fluctuation

Recently the second phase of Background Imaging of Cosmic Extragalactic Polarization （BICEP2） claimed a detection of the tensor-to-scalar ratio （r） of primordial fluctuation at 50- confidence level. If it is true, this large and measurable amplitude （r - 0.2） of B-mode polarization indicates that it is possible to measure the shape of CMB B-mode polarization with future experiments. Given the current understanding of the experimental noise and foreground contamination, we forecast the precision of r and the tensor spectral index nt measurements from Planck, Spider and POLARBEAR with nt as a free parameter. We quantitatively determine the signal-to-noise of the measurement in r-nt parameter space for the three experiments. The forecasted signal-to-noise ratio of the B-mode polarization somewhat depends on r/t, but strongly depends on the true value of r.

新书架

(美)莱斯特·R·布朗 著林自新 暴永宁 等译东方出版社定价:21.00元 现代文明正处在困境之中。