The P XIII spectrum has been analyzed by several authors using different light sources. The semi-empirical oscillator strengths (gf) and the lifetimes presented in this work for all known P XIII spectral lines and ene...The P XIII spectrum has been analyzed by several authors using different light sources. The semi-empirical oscillator strengths (gf) and the lifetimes presented in this work for all known P XIII spectral lines and energy levels were carried out in a multi-configuration Hartree-Fock relativistic (HFR) approach. In this calculation, the electrostatic parameters were optimized by a least-squares procedure in order to improve the adjustment of theoretical to experimental energy levels. The method produces gf-values that are in agreement with intensity observations and lifetime values closer to the experimental ones.展开更多
Objective： To provide a comprehensive literature review on roles of coagulation factor XIII （FXIII） in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy. Data Sources： All articles in PubMed wit...Objective： To provide a comprehensive literature review on roles of coagulation factor XIII （FXIII） in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy. Data Sources： All articles in PubMed with key words ＂Coagulation factor XIII＂, ＂wound＂, ＂＇leukeraia＂, ＂tumor＂, ＂bone,＂ and ＂pregnancy＇＂ with published date from 2001 to 2016 were included in the study. Frequently cited publications before 2000 were also included. Study Selection： We reviewed the role of FXIll in biologic processes as documented in clinical, animal, and in vitro studies. Results： FXIII, a nlember of the transglutaminase （TG） family, plays key roles in various biological processes. Besides its well-known function in coagulation, the cross-linking of small molecules catalyzed by FXIII has been found in studies to help promote wound healing, improve bone metabolism, and prevent miscarriages. The study has also shown that FXIII concentration level differs in the blood of patients with leukemia and solid tumors and offers promises as a diagnostic indicator Conclusions： FXIII has many more biologic functions besides being known as coagulation factor. The TG activity of FXIII contributes to several processes, including wound healing, bone extracellular matrix stabilization, and the interaction between embryo and decidua of uterus. Further research is needed to elucidate the link between FXIII and leukemia and solid tumors.展开更多
BACKGROUND： Recurrent pregnancy loss （RPL） is a heterogeneous condition and thrombophilias have been considered as a probable cause. OBJECTIVE： The aim of this study was to investigate the prevalence of the coagul...BACKGROUND： Recurrent pregnancy loss （RPL） is a heterogeneous condition and thrombophilias have been considered as a probable cause. OBJECTIVE： The aim of this study was to investigate the prevalence of the coagulation factor XIII Va134Leu polymorphism among women with unexplained RPL. METHODS： A total of 140 women with a history of unexplained RPL and 100 age-matched healthy fertile women were recruited. The presence of FXIII Va134Leu polymorphism among the cases and controls was investigated using PCR-RFLP method. RESULTS： Genotype analyses of the subjects revealed that the patients had a significantly higher prevalence of V/L and L/L than the controls （P〈 0.05）： 33.5% vs. 15%, and 9.2% vs. 2%, respectively. CONCLUSION： These results indicate a significant association between FXIII Va134Leu polymorphism and unexplained RPL in the Iranian patient.展开更多
文摘The P XIII spectrum has been analyzed by several authors using different light sources. The semi-empirical oscillator strengths (gf) and the lifetimes presented in this work for all known P XIII spectral lines and energy levels were carried out in a multi-configuration Hartree-Fock relativistic (HFR) approach. In this calculation, the electrostatic parameters were optimized by a least-squares procedure in order to improve the adjustment of theoretical to experimental energy levels. The method produces gf-values that are in agreement with intensity observations and lifetime values closer to the experimental ones.
基金the Key Program of Chinese People’s Armed Police Forces,No.WKH2009Z04the Program of Logistics College of Chinese People’s Armed Police Forces,No.WHM201209~~
文摘Objective： To provide a comprehensive literature review on roles of coagulation factor XIII （FXIII） in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy. Data Sources： All articles in PubMed with key words ＂Coagulation factor XIII＂, ＂wound＂, ＂＇leukeraia＂, ＂tumor＂, ＂bone,＂ and ＂pregnancy＇＂ with published date from 2001 to 2016 were included in the study. Frequently cited publications before 2000 were also included. Study Selection： We reviewed the role of FXIll in biologic processes as documented in clinical, animal, and in vitro studies. Results： FXIII, a nlember of the transglutaminase （TG） family, plays key roles in various biological processes. Besides its well-known function in coagulation, the cross-linking of small molecules catalyzed by FXIII has been found in studies to help promote wound healing, improve bone metabolism, and prevent miscarriages. The study has also shown that FXIII concentration level differs in the blood of patients with leukemia and solid tumors and offers promises as a diagnostic indicator Conclusions： FXIII has many more biologic functions besides being known as coagulation factor. The TG activity of FXIII contributes to several processes, including wound healing, bone extracellular matrix stabilization, and the interaction between embryo and decidua of uterus. Further research is needed to elucidate the link between FXIII and leukemia and solid tumors.
文摘BACKGROUND： Recurrent pregnancy loss （RPL） is a heterogeneous condition and thrombophilias have been considered as a probable cause. OBJECTIVE： The aim of this study was to investigate the prevalence of the coagulation factor XIII Va134Leu polymorphism among women with unexplained RPL. METHODS： A total of 140 women with a history of unexplained RPL and 100 age-matched healthy fertile women were recruited. The presence of FXIII Va134Leu polymorphism among the cases and controls was investigated using PCR-RFLP method. RESULTS： Genotype analyses of the subjects revealed that the patients had a significantly higher prevalence of V/L and L/L than the controls （P〈 0.05）： 33.5% vs. 15%, and 9.2% vs. 2%, respectively. CONCLUSION： These results indicate a significant association between FXIII Va134Leu polymorphism and unexplained RPL in the Iranian patient.
