目的:观察柴胡桂枝干姜汤治疗上热下寒型失眠的临床疗效。方法:选择2023年4—10月安阳市中医院脑病三科门诊诊治的100例上热下寒型失眠患者,按照随机数字表法分为对照组和试验组,每组各50例。对照组给予艾司唑仑片治疗,试验组给予柴胡...目的:观察柴胡桂枝干姜汤治疗上热下寒型失眠的临床疗效。方法:选择2023年4—10月安阳市中医院脑病三科门诊诊治的100例上热下寒型失眠患者,按照随机数字表法分为对照组和试验组,每组各50例。对照组给予艾司唑仑片治疗,试验组给予柴胡桂枝干姜汤加减治疗。比较两组患者的临床疗效、不良反应积分及治疗前后中医证候积分、匹兹堡睡眠治疗指数、世界卫生组织生存质量测定量表简表(the world health organization quality of life scale,WHOQOL-BREF)积分变化情况。结果:两组患者治疗后中医证候积分低于本组治疗前,且治疗后试验组低于对照组(P<0.05)。试验组有效率为92.0%,高于对照组的86.0%,差异有统计学意义(P<0.05)。两组患者治疗后匹兹堡睡眠指数低于本组治疗前,且治疗后试验组低于对照组(P<0.05)。两组患者治疗后WHOQOL-BREF评分高于本组治疗前,且治疗后试验组高于对照组(P<0.05)。对照组不良反应积分为(2.72±0.73)分,试验组不良反应积分为(0.60±0.67)分,差异具有统计学意义(P<0.05)。结论:柴胡桂枝干姜汤加减治疗上热下寒型失眠临床疗效确切,可改善患者的临床症状,提高睡眠质量及生活质量。展开更多
介绍王作顺教授以经方为主辨证治疗上热下寒病证的临床经验。上热下寒证属寒热错杂的复杂临床证候,其基本病机为人体阴阳气机升降失常。王作顺教授认为,现代人由于饮食不节、起居失常、精神压力等各种因素而常见上热下寒体质,并在临床...介绍王作顺教授以经方为主辨证治疗上热下寒病证的临床经验。上热下寒证属寒热错杂的复杂临床证候,其基本病机为人体阴阳气机升降失常。王作顺教授认为,现代人由于饮食不节、起居失常、精神压力等各种因素而常见上热下寒体质,并在临床辨证中擅长运用乌梅丸、柴胡桂枝干姜汤等经方加减化裁,运用平调寒热之法加以治疗,使机体达阴平阳秘之态而获痊愈。This article introduces Professor Wang Zuoshun’s clinical experience in treating upper heat and lower cold syndrome, a complex clinical condition characterized by mixed cold and heat, primarily with classical formulas based on syndrome differentiation. The fundamental pathogenesis of this syndrome involves the imbalance of ascending and descending movements of Yin and Yang qi in the human body. Professor Wang Zuoshun believes that modern individuals commonly exhibit an upper heat and lower cold constitution due to various factors such as improper diet, irregular lifestyle, and mental stress. In clinical syndrome differentiation, he excels at using modified versions of classical formulas such as Wumei Pill and Chaihu Guizhi Ganjiang Decoction, employing methods to harmonize cold and heat, thereby restoring the body to a state of balanced Yin and Yang and achieving recovery.展开更多
文摘目的:观察柴胡桂枝干姜汤治疗上热下寒型失眠的临床疗效。方法:选择2023年4—10月安阳市中医院脑病三科门诊诊治的100例上热下寒型失眠患者,按照随机数字表法分为对照组和试验组,每组各50例。对照组给予艾司唑仑片治疗,试验组给予柴胡桂枝干姜汤加减治疗。比较两组患者的临床疗效、不良反应积分及治疗前后中医证候积分、匹兹堡睡眠治疗指数、世界卫生组织生存质量测定量表简表(the world health organization quality of life scale,WHOQOL-BREF)积分变化情况。结果:两组患者治疗后中医证候积分低于本组治疗前,且治疗后试验组低于对照组(P<0.05)。试验组有效率为92.0%,高于对照组的86.0%,差异有统计学意义(P<0.05)。两组患者治疗后匹兹堡睡眠指数低于本组治疗前,且治疗后试验组低于对照组(P<0.05)。两组患者治疗后WHOQOL-BREF评分高于本组治疗前,且治疗后试验组高于对照组(P<0.05)。对照组不良反应积分为(2.72±0.73)分,试验组不良反应积分为(0.60±0.67)分,差异具有统计学意义(P<0.05)。结论:柴胡桂枝干姜汤加减治疗上热下寒型失眠临床疗效确切,可改善患者的临床症状,提高睡眠质量及生活质量。
文摘介绍王作顺教授以经方为主辨证治疗上热下寒病证的临床经验。上热下寒证属寒热错杂的复杂临床证候,其基本病机为人体阴阳气机升降失常。王作顺教授认为,现代人由于饮食不节、起居失常、精神压力等各种因素而常见上热下寒体质,并在临床辨证中擅长运用乌梅丸、柴胡桂枝干姜汤等经方加减化裁,运用平调寒热之法加以治疗,使机体达阴平阳秘之态而获痊愈。This article introduces Professor Wang Zuoshun’s clinical experience in treating upper heat and lower cold syndrome, a complex clinical condition characterized by mixed cold and heat, primarily with classical formulas based on syndrome differentiation. The fundamental pathogenesis of this syndrome involves the imbalance of ascending and descending movements of Yin and Yang qi in the human body. Professor Wang Zuoshun believes that modern individuals commonly exhibit an upper heat and lower cold constitution due to various factors such as improper diet, irregular lifestyle, and mental stress. In clinical syndrome differentiation, he excels at using modified versions of classical formulas such as Wumei Pill and Chaihu Guizhi Ganjiang Decoction, employing methods to harmonize cold and heat, thereby restoring the body to a state of balanced Yin and Yang and achieving recovery.