The most commonly found fingermarks at crime scenes are latent and, thus, an efficient method for detecting latent fingermarks is very important. However, traditional developing techniques have drawbacks such as low d...The most commonly found fingermarks at crime scenes are latent and, thus, an efficient method for detecting latent fingermarks is very important. However, traditional developing techniques have drawbacks such as low detection sensitivity, high background interference, complicated operation, and high toxicity. To tackle this challenge, we employed fluorescent NaYF4：Yb, Er upconversion nanoparticles （UCNPs）, which can fluoresce visible light when excited by 980 nm human-safe near-infrared light, to stain the latent fingermarks on various substrate surfaces. The UCNPs were successfully used as a novel fluorescent label for the detection of latent fingermarks with high sensitivity, low background, high efficiency, and low toxicity on various substrates including non-infiltrating materials （glass, marble, aluminum alloy sheets, stainless steel sheets, aluminum foils, and plastic cards）, semi-infiltrating materials （floor leathers, ceramic tiles, wood floor, and painted wood）, and infiltrating materials such as various types of papers. This work shows that UCNPs are a versatile fluorescent label for the facile detection of fingermarks on virtually any material, enabling their practical applications in forensic sciences.展开更多
基金This work is supported by the National Natural Science Foundation of China （No. 21205139）, the Application and Innovation Project of Chinese Ministry of Public Security （No. 2012YYCXXJXY127）, and the Program for Liaoning Excellent Talents in University （No. LJQ2014130）. MYY is thankful for the grant support from the National Natural Science Foundation of China （Nos. 20804037 and 21172194） and National High Technology Research and Development Program 863 （No. 2013AA102507）. YZ, PHQ and CBM would like to thank the financial support from National Institutes of Health （No. EB015190）, National Natural Science Foundation （No. CMMI-1234957 and DMR-0847758）, Department of Defense Peer Reviewed Medical Research Program （No. W81XWH-12-1-0384）, Oklahoma Center for the Advancement of Science and Technology （No. HR14-160） and Oklahoma Center for Adult Stem Cell Research （No. 434003）.
文摘The most commonly found fingermarks at crime scenes are latent and, thus, an efficient method for detecting latent fingermarks is very important. However, traditional developing techniques have drawbacks such as low detection sensitivity, high background interference, complicated operation, and high toxicity. To tackle this challenge, we employed fluorescent NaYF4：Yb, Er upconversion nanoparticles （UCNPs）, which can fluoresce visible light when excited by 980 nm human-safe near-infrared light, to stain the latent fingermarks on various substrate surfaces. The UCNPs were successfully used as a novel fluorescent label for the detection of latent fingermarks with high sensitivity, low background, high efficiency, and low toxicity on various substrates including non-infiltrating materials （glass, marble, aluminum alloy sheets, stainless steel sheets, aluminum foils, and plastic cards）, semi-infiltrating materials （floor leathers, ceramic tiles, wood floor, and painted wood）, and infiltrating materials such as various types of papers. This work shows that UCNPs are a versatile fluorescent label for the facile detection of fingermarks on virtually any material, enabling their practical applications in forensic sciences.
