By analyzing the change of an index for the characteristics of South Asia High and variations of upper-air troughs in 2002–2005,we studied the impact of South Asia high on the beginning and ending of the Mei-yu(i.e.s...By analyzing the change of an index for the characteristics of South Asia High and variations of upper-air troughs in 2002–2005,we studied the impact of South Asia high on the beginning and ending of the Mei-yu(i.e.sustained rain corresponding to the ripening season of plum)in Jiangsu province.Statistic verification is conducted on the relationships between the index and the Mei-yu season in 1991–2005 to examine the impacts of the SAH characteristics index on a rain intensity index of Mei-yu and regional distribution of a characteristics index for different annual patterns of Mei-yu.Historical composite is performed of the 100-hPa circulation field for these patterns using the 100-hPa geopotential height of Northern Hemisphere from 2002 to 2005 and 45-year NCEP reanalysis to study the difference in the circulation for different patterns of Mei-yu.Diagnostic and statistic conclusions,which share much in common,have been obtained as follows.(1)The characteristics preceding to and the advancement/retreat of SAH and the movement of westerly troughs are the factors that influence the onset time of the Mei-yu season;after the Mei-yu onset,the progression/withdrawal of SAH and how farther east it extends are determining how long the Mei-yu lasts and when it ends.(2)During the Mei-yu,the general 100-hPa circulation situation and average characteristics of the SAH are well corresponding to the characteristics of the season and annual patterns of Mei-yu.In addition,the averages of the SAH ridgeline and east-extending index for June,July and the Mei-yu season have some implications to the forecast of the index of Mei-yu intensity.These conclusions can be served as powerful means in determining the starting/ending dates, duration and annual pattern of the Mei-yu season.展开更多
Objective To analyze the reasons of misdiagnosis of primary syphilitic chancre and strengthen the understanding of atypical features of this disease.Methods A case series of twenty-seven challenging primary syphilis p...Objective To analyze the reasons of misdiagnosis of primary syphilitic chancre and strengthen the understanding of atypical features of this disease.Methods A case series of twenty-seven challenging primary syphilis patients who were not immediately recognized as chancre was included in our study.The clinical data including the patients’age,sex,skin lesions,HIV status,syphilis serologic test results,treatment,and follow-up results were collected.Hematoxylin-eosin and immunohistochemistry staining of skin biopsy sections were reviewed.Results Four female cases with extragenital chancres presenting as erythema or erosive skin lesions on the nipple were misdiagnosed as Paget’s disease or eczema.The disorder of missed or misdiagnosed male cases manifested as syphilitic balanitis or multiple chancres on the penis root and adjacent pubis rather than coronal sulcus or frenum.Patients with nonreactive nontreponemal tests at initial presentation were also easily missed or misdiagnosed.Conclusion Primary syphilis presenting as multiple lesions rather than a single chancre,at atypical locations,or with a nonreactive nontreponemal test result,tends to be missed or misdiagnosed.展开更多
Objective: To study the occurrence and development ofprimary syphilis from a morphological and structural aspect.Method: The ultrastructural pathological changes of syphiliticchancre were examined by transmission elec...Objective: To study the occurrence and development ofprimary syphilis from a morphological and structural aspect.Method: The ultrastructural pathological changes of syphiliticchancre were examined by transmission electron microscopy(TEM). Results: The pathological changes of syphilitic chancreoccur mainly in the dermal layer, manifested as partialthinning or lysis of the capillary basal membrane,proliferation of capillary endothelial cells, thickening of somecollagen fibers and rupture of collagen fibers surrounding Tpallidum, structural disruption of the axons of terminal nerves,disarrangement of the sheath of the myelinated nerve fiberswith separation of laminae and the attachment of T pallidumon its outer membrane, appearance of slightly swollen Tpallidum in the plasma of the capillary endothelial cells andfibroblasts, and infiltration of neutrophils, macrophages andplasma cells containing T pallidum and its debris frequentlylined by a clear sheath. Conclusion: The pathogenesis and injury of mechanism inprimary syphilis can be explained morphologically by itscharacteristic ultrastructural pathological changes.展开更多
This case report describes an extremely rare complication of a Meckel's diverticulum:enterocutaneous fistula of the diverticulum.The presence of Meckel's diverticulum is a well known entity,but subcutaneous pe...This case report describes an extremely rare complication of a Meckel's diverticulum:enterocutaneous fistula of the diverticulum.The presence of Meckel's diverticulum is a well known entity,but subcutaneous perforation of the diverticulum is very rare.Here we report the case of a patient with the complaint of a right lower quadrant abscess,preoperatively diagnosed as enterocutaneous fistula,which was determined intraoperatively to be a fistula resulting from Meckel's diverticulum.展开更多
Research data showed that syndromic approach could successfully manage gonococcal and chlamydial infections in males and syphilis and chancroid in males and females. However, low sensitivity, specificity and positive ...Research data showed that syndromic approach could successfully manage gonococcal and chlamydial infections in males and syphilis and chancroid in males and females. However, low sensitivity, specificity and positive predictive value were found in the syndromic management of vaginal discharge. It is recommended that the syndromic algorithm for management of vaginal discharge used when serving high-risk and symptomatic women.展开更多
基金Special Projects for Forecaster China Meteorological Administration(CMAYBY2011-017)
文摘By analyzing the change of an index for the characteristics of South Asia High and variations of upper-air troughs in 2002–2005,we studied the impact of South Asia high on the beginning and ending of the Mei-yu(i.e.sustained rain corresponding to the ripening season of plum)in Jiangsu province.Statistic verification is conducted on the relationships between the index and the Mei-yu season in 1991–2005 to examine the impacts of the SAH characteristics index on a rain intensity index of Mei-yu and regional distribution of a characteristics index for different annual patterns of Mei-yu.Historical composite is performed of the 100-hPa circulation field for these patterns using the 100-hPa geopotential height of Northern Hemisphere from 2002 to 2005 and 45-year NCEP reanalysis to study the difference in the circulation for different patterns of Mei-yu.Diagnostic and statistic conclusions,which share much in common,have been obtained as follows.(1)The characteristics preceding to and the advancement/retreat of SAH and the movement of westerly troughs are the factors that influence the onset time of the Mei-yu season;after the Mei-yu onset,the progression/withdrawal of SAH and how farther east it extends are determining how long the Mei-yu lasts and when it ends.(2)During the Mei-yu,the general 100-hPa circulation situation and average characteristics of the SAH are well corresponding to the characteristics of the season and annual patterns of Mei-yu.In addition,the averages of the SAH ridgeline and east-extending index for June,July and the Mei-yu season have some implications to the forecast of the index of Mei-yu intensity.These conclusions can be served as powerful means in determining the starting/ending dates, duration and annual pattern of the Mei-yu season.
基金Supported by Beijing Municipal Science and Technology Commission(Z191100006619011)Capital’s Funds for Health Improvement and Research(2020-2-4016)。
文摘Objective To analyze the reasons of misdiagnosis of primary syphilitic chancre and strengthen the understanding of atypical features of this disease.Methods A case series of twenty-seven challenging primary syphilis patients who were not immediately recognized as chancre was included in our study.The clinical data including the patients’age,sex,skin lesions,HIV status,syphilis serologic test results,treatment,and follow-up results were collected.Hematoxylin-eosin and immunohistochemistry staining of skin biopsy sections were reviewed.Results Four female cases with extragenital chancres presenting as erythema or erosive skin lesions on the nipple were misdiagnosed as Paget’s disease or eczema.The disorder of missed or misdiagnosed male cases manifested as syphilitic balanitis or multiple chancres on the penis root and adjacent pubis rather than coronal sulcus or frenum.Patients with nonreactive nontreponemal tests at initial presentation were also easily missed or misdiagnosed.Conclusion Primary syphilis presenting as multiple lesions rather than a single chancre,at atypical locations,or with a nonreactive nontreponemal test result,tends to be missed or misdiagnosed.
文摘Objective: To study the occurrence and development ofprimary syphilis from a morphological and structural aspect.Method: The ultrastructural pathological changes of syphiliticchancre were examined by transmission electron microscopy(TEM). Results: The pathological changes of syphilitic chancreoccur mainly in the dermal layer, manifested as partialthinning or lysis of the capillary basal membrane,proliferation of capillary endothelial cells, thickening of somecollagen fibers and rupture of collagen fibers surrounding Tpallidum, structural disruption of the axons of terminal nerves,disarrangement of the sheath of the myelinated nerve fiberswith separation of laminae and the attachment of T pallidumon its outer membrane, appearance of slightly swollen Tpallidum in the plasma of the capillary endothelial cells andfibroblasts, and infiltration of neutrophils, macrophages andplasma cells containing T pallidum and its debris frequentlylined by a clear sheath. Conclusion: The pathogenesis and injury of mechanism inprimary syphilis can be explained morphologically by itscharacteristic ultrastructural pathological changes.
文摘This case report describes an extremely rare complication of a Meckel's diverticulum:enterocutaneous fistula of the diverticulum.The presence of Meckel's diverticulum is a well known entity,but subcutaneous perforation of the diverticulum is very rare.Here we report the case of a patient with the complaint of a right lower quadrant abscess,preoperatively diagnosed as enterocutaneous fistula,which was determined intraoperatively to be a fistula resulting from Meckel's diverticulum.
文摘Research data showed that syndromic approach could successfully manage gonococcal and chlamydial infections in males and syphilis and chancroid in males and females. However, low sensitivity, specificity and positive predictive value were found in the syndromic management of vaginal discharge. It is recommended that the syndromic algorithm for management of vaginal discharge used when serving high-risk and symptomatic women.
