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放疗后复发的晚期上段食管癌内镜下缩瘤术的临床价值
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作者 杨书红 郭金东 +2 位作者 刘俊 赵建华 李明峰 《现代消化及介入诊疗》 2023年第7期894-900,共7页
目的针对放疗后复发的晚期上段食管癌实施内镜下缩瘤术,评价该技术的安全性、可行性和有效性。方法收集我院、中国人民解放军海军特色医学中心消化内科和上海市胸科医院放疗科2014.1.1-2022.10.31因放疗后复发的晚期上段食管癌82例,分... 目的针对放疗后复发的晚期上段食管癌实施内镜下缩瘤术,评价该技术的安全性、可行性和有效性。方法收集我院、中国人民解放军海军特色医学中心消化内科和上海市胸科医院放疗科2014.1.1-2022.10.31因放疗后复发的晚期上段食管癌82例,分为缩瘤术治疗组(内镜下球囊扩张+氩离子凝固术(APC)和对照组(单纯内镜下球囊扩张)。治疗组43例,对照组39例。治疗组d1内镜下球囊扩张+APC,d8视狭窄情况决定是否行球囊扩张,但均行APC治疗,治疗结束后休息20天行第二个疗程,共治疗3个周期(84天),对照组治疗时间和周期同治疗组。评估患者梗阻等级、KPS评分、疼痛评分、血红蛋白水平等指标,观察患者食道梗阻的再通、进食状态的改善、病灶出血的控制及球囊扩张的频次等情况。结果治疗组和对照组d1均需实施内镜下球囊扩张,以内镜是否能在扩张后顺利通过狭窄段作为扩张效果的评判,治疗组和对照组扩张成功率为39例(90.6%)和37例(94.8%),d8治疗组21例(48.8%),对照组35例(89.7%)均需再次扩张;在后续的两疗程中,治疗组有7例(16.27%)病人因出现不同程度的梗阻需行球囊扩张,而对照组中有36例(92.3%)(P<0.001)出现不同程度再狭窄并需要再次行球囊扩张治疗。三个疗程结束后随访患者再狭窄而接受球囊扩张的间隔时间,治疗组平均61.25日,显著优于对照组32.20日(P<0.001)。治疗组3疗程后平均血红蛋白水平、疼痛评分优于对照组(P=0.047、0.028);两组间治疗前后平均KPS评分、梗阻等级没有统计学差异。ETR组的中位OS为12.71个月较对照组的10.23个月延长(P=0.048)。ETR组的半年、1年、2年生存率为90.7%、60.5%、34.9%,对照组的半年、1年、2年生存率为84.7%、35.9%、21.5%,其中1年生存率差异有统计学意义(P=0.047)。结论内镜下缩瘤术可以作为放疗后复发的晚期上段食管癌患者有效的治疗方法,较单纯内镜下扩张治疗具有:肿瘤负荷减轻明显,病人进食状态改善显著,扩张治疗周期明显延长,在控制患者病灶慢性出血、改善疼痛等体验上有显著意义,解决了该类病人因位置过高而不能放置支架或支架放置后极易引发出血的风险,值得在临床工作中积极推广。 展开更多
关键词 上段食管癌 放射治疗 食道梗阻 内镜下球囊扩张术 内镜下缩瘤术 氩离子凝固术
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内镜下缩瘤术治疗老年晚期胃癌的临床疗效 被引量:1
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作者 李朝燕 顾剑锋 +4 位作者 丁威 席素娟 岳海燕 熊伟民 李明峰 《世界华人消化杂志》 CAS 2016年第28期3991-3997,共7页
目的回顾性分析106例老年晚期胃癌病例,评价内镜下缩瘤术对老年晚期胃癌预后的影响.方法将收集的老年晚期胃癌病例分为采用内镜下缩瘤术治疗的治疗组和仅接受最佳支持治疗的同期对照组,主要观察指标为有效率和生存期.完成4疗程以上缩瘤... 目的回顾性分析106例老年晚期胃癌病例,评价内镜下缩瘤术对老年晚期胃癌预后的影响.方法将收集的老年晚期胃癌病例分为采用内镜下缩瘤术治疗的治疗组和仅接受最佳支持治疗的同期对照组,主要观察指标为有效率和生存期.完成4疗程以上缩瘤术治疗后评估短期疗效及不良反应.采用Cox多因素分析方法 ,在基线均衡的条件下比较两组胃癌病例的生存期,Kaplan-Meier法估算中位生存时间.结果收集中国人民解放军第455医院消化肿瘤科2010-01-01/2015-06-30诊治的老年晚期胃癌患106例,治疗组为51例,对照组为55例,治疗组和对照组的近期有效率分别为76.5%和27.3%(P<0.05).C o x多因素回归分析示:内镜下缩瘤治疗(P=0.000)、肿瘤大小(P=0.000)是影响老年晚期胃癌病例生存期的独立的预后因素,在组间基线均衡的条件下,治疗组(51例)的中位生存期较对照组(55例)延长(12.496 mo vs 8.384 mo,P=0.000),采用内镜下缩瘤治疗的相对危险度:0.430(95%CI:0.274-0.675).治疗组1、2年生存率较对照组明显延长(52.8%vs 29.1%、22.9%vs 2.8%).结论内镜下缩瘤术对晚期胃癌具有较好临床疗效,可延长老年晚期胃癌患者的生存期,使其生存获益. 展开更多
关键词 晚期胃癌 老年 内镜下缩瘤术 生存期 预后
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CAD三维建模在矿井非正规煤仓下缩口施工中的应用 被引量:3
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作者 陈业强 李洋 陈磊 《内蒙古煤炭经济》 2019年第12期152-152,154,共2页
本文以福城矿业公司+740三号煤仓下缩口施工为例,介绍CAD三维设计在矿井大型非正规煤仓下缩口施工中的应用。通过绘制煤仓下缩口三维立体图,可以快速提取浇筑碹弓子的尺寸及下缩口施工大样图,为大型非正规煤仓下缩口的施工控制带来了便利。
关键词 煤仓下缩 建模 混凝土浇筑
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大直径嵌岩桩残余应变状态分析 被引量:5
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作者 印长俊 王星华 夏力农 《岩土力学》 EI CAS CSCD 北大核心 2008年第11期3095-3098,共4页
通过对2根大直径嵌岩灌注桩(人工挖孔)加载前应变状态连续监测,初步分析了桩身残余产生的原因、分布规律和对桩受力性状的影响,并得到如下结论:(1)混凝土的干缩是产生残余应变的主要因素;(2)桩身的残余应变随空间和时间变化是有规律的,... 通过对2根大直径嵌岩灌注桩(人工挖孔)加载前应变状态连续监测,初步分析了桩身残余产生的原因、分布规律和对桩受力性状的影响,并得到如下结论:(1)混凝土的干缩是产生残余应变的主要因素;(2)桩身的残余应变随空间和时间变化是有规律的,但诸多施工因素(如爆破,地下水和浇注方式)会使其分布不均匀或弱化桩侧岩石的约束力;(3)桩身局部的残余应变会超过混凝土的极限拉应变而产生裂缝,失去对桩身钢筋的保护能力,并且桩身整体收缩会减小桩端与地基的接触力。以上结论可为工程实践提供参考。 展开更多
关键词 大直径 嵌岩桩 下缩 残余应变 温度
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综放支架液压系统可靠性实测分析 被引量:4
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作者 张玉国 何富连 +2 位作者 臧传伟 瞿群迪1刘克功 赵洪亮 《矿山压力与顶板管理》 2000年第3期12-14,共3页
根据五阳煤矿综放采场液压支架活柱下缩量的实测数据 ,运用方差分析方法对支架活柱下缩量进行显著性检验和考察支架液压系统可靠性 ,进而推出支架立柱液压系统可靠性的评判标准。
关键词 液压系统 综放支架 一元方差分析 活柱下缩 可靠性
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基于三量协同监测的采场来压识别预警系统研发 被引量:3
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作者 万勇 《自动化仪表》 CAS 2020年第8期91-95,102,共6页
根据《2013-2017年度全国煤矿安全事故案例汇编》,煤矿矿压监测单纯依靠应力监测和人工测距,存在工作量大、值班人员多、稳定性低的现状。对近几年煤矿采场来压、支架工作阻力、顶底板移近量、活柱下缩量监测进行了研究,创新性地研究了... 根据《2013-2017年度全国煤矿安全事故案例汇编》,煤矿矿压监测单纯依靠应力监测和人工测距,存在工作量大、值班人员多、稳定性低的现状。对近几年煤矿采场来压、支架工作阻力、顶底板移近量、活柱下缩量监测进行了研究,创新性地研究了基于三量协同监测采场来压识别和预警系统。该系统能对顶板周期来压时间、步距、强度、支架倾角、支柱移近速率及升降状态等作记录分析,并对下一周期来压进行预测,减少了顶板监测人员数量,提高了劳动效率,实现了减员增效。该研究成果对贯彻落实《关于开展“机械化换人、自动化减人”科技强安专项行动的通知(安监总科技[2015]63号)》起到积极、有效的推进作用,并对煤矿采场矿压研究理论、控制技术及顶板灾害预测相关科研课题起到抛砖引玉效应,具有广阔的市场前景。 展开更多
关键词 采场来压 支架工作阻力 顶底板移近量 活柱下缩 三量协同 离层位移 移近量 围岩应力
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集贤煤矿五层煤矿压显现规律
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作者 任玉民 刘绍文 《黑龙江科技信息》 2004年第2期48-48,共1页
双矿集团集贤煤矿五层煤是集贤煤矿乃至双矿集团的主力煤层,我们在回采五层煤首采面4305一片时由于没有对五层煤进行矿压观测,我们用经验公式计算支护密度,致使工作面靠煤壁处多次切开,形成台阶下沉,使工作面单体支柱大量损坏,大... 双矿集团集贤煤矿五层煤是集贤煤矿乃至双矿集团的主力煤层,我们在回采五层煤首采面4305一片时由于没有对五层煤进行矿压观测,我们用经验公式计算支护密度,致使工作面靠煤壁处多次切开,形成台阶下沉,使工作面单体支柱大量损坏,大量单体被压靠,给生产期间回撤单体工作造成很大困难,同时也有赴掌子的危险,为了解决这个问题。 展开更多
关键词 煤矿 顶板矿压 显现规律 活柱下缩 底裤钻底量 支柱载荷
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三软煤层工作面矿压显现规律实测研究 被引量:2
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作者 孙平勇 李洪彪 《江西煤炭科技》 2014年第3期168-170,共3页
通过现场实测,掌握了三软煤层21090综采工作面的来压步距、来压强度、动载系数、煤壁片帮和活柱下缩变化等矿压显现规律,分析了采场液压支架的适应性。提出提高支架初撑力、加快推进速度和利用矿压显现规律提前加固煤壁和顶板等安全措... 通过现场实测,掌握了三软煤层21090综采工作面的来压步距、来压强度、动载系数、煤壁片帮和活柱下缩变化等矿压显现规律,分析了采场液压支架的适应性。提出提高支架初撑力、加快推进速度和利用矿压显现规律提前加固煤壁和顶板等安全措施来控制片帮和顶板冒漏,该研究成果为宁庄井三软煤层的安全开采提供了科学实测依据。 展开更多
关键词 三软煤层 矿压规律 片帮 活柱下缩
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基于长观孔水位变化的压架突水灾害预警 被引量:1
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作者 李晋 《山西焦煤科技》 2018年第1期10-13,共4页
基于长观孔水位的变化,以某矿松散含水层采煤工作面回采为研究背景,研究松散含水层采煤工作面压架突水灾害预警。研究结果表明:水位与采动之间存在联动关系,即工作面回采便会引起长观孔水位的升降变化。通过计算近2~3天的平均降速,并与... 基于长观孔水位的变化,以某矿松散含水层采煤工作面回采为研究背景,研究松散含水层采煤工作面压架突水灾害预警。研究结果表明:水位与采动之间存在联动关系,即工作面回采便会引起长观孔水位的升降变化。通过计算近2~3天的平均降速,并与预警值对比,若发现水位呈连续下降现象,水位降深累计超过1 m,再结合工作面压力情况,如果工作面普遍剧烈来压并发生活柱大量下缩的情况,那么需要发布压架突水灾害预警,同时依据地质条件建立了基于长观孔水位降速的压架突水灾害预警系统。 展开更多
关键词 工作面回采 长观孔水位 活柱下缩 压架突水
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Rock burst proneness prediction by acoustic emission test during rock deformation 被引量:14
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作者 张志镇 高峰 尚晓吉 《Journal of Central South University》 SCIE EI CAS 2014年第1期373-380,共8页
Rock burst is a severe disaster in mining and underground engineering,and it is important to predict the rock burst risk for minimizing the loss during the constructing process.The rock burst proneness was connected w... Rock burst is a severe disaster in mining and underground engineering,and it is important to predict the rock burst risk for minimizing the loss during the constructing process.The rock burst proneness was connected with the acoustic emission(AE) parameter in this work,which contributes to predicting the rock burst risk using AE technique.Primarily,a rock burst proneness index is proposed,and it just depends on the heterogeneous degree of rock material.Then,the quantificational formula between the value of rock burst proneness index and the accumulative AE counts in rock sample under uniaxial compression with axial strain increases is developed.Finally,three kinds of rock samples,i.e.,granite,limestone and sandstone are tested about variation of the accumulative AE counts under uniaxial compression,and the test data are fitted well with the theoretic formula. 展开更多
关键词 rock mechanics rock burst proneness PREDICTION accumulative acoustic emission counts Weibull statistical distribution
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Numerical Calculation of Supercavitating Flows over the Disk Cavitator of a Subsonic Underwater Projectile 被引量:3
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作者 Qingchang Meng Zhihong Zhang Jubin Liu 《Journal of Marine Science and Application》 CSCD 2015年第3期283-289,共7页
To deal with the effect of compressible fluids on the supercavitating flow over the subsonic disk cavitator of a projectile, a finite volume method is formulated based on the ideal compressible potential theory. By us... To deal with the effect of compressible fluids on the supercavitating flow over the subsonic disk cavitator of a projectile, a finite volume method is formulated based on the ideal compressible potential theory. By using the continuity equation and Tait state equation as well as Riabouchinsky closure model, an“inverse problem”solution is presented for the supercavitating flow. According to the impenetrable condition on the surface of supercavity, a new iterative method for the supercavity shape is designed to deal with the effect of compressibility on the supercavity shape, pressure drag coefficient and density field. By this method, the very low cavitation number can be computed. The calculated results agree well with the experimental data and empirical formula. At the subsonic condition, the fluid compressibility will make supercavity length and radius increase. The supercavity expands, but remains spheroid. The effect on the first 1/3 part of supercavity is not obvious. The drag coefficient of projectile increases as the cavitation number or Mach number increases. With Mach number increasing, the compressibility is more and more significant. The compressibility must be considered as far as the accurate calculation of supercavitating flow is concerned. 展开更多
关键词 underwater projectile subsonic projectile SUPERCAVITATION supercavitating flow finite volume method potential flow fluid mechanics disk cavitator
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Time Evolution and Squeezing of Degenerate and Non-degenerate Coupled Parametric Down-Conversion with Driving Term
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作者 LI Jiang-Fan FANG Jia-Yuan XIAO Fu-Liang LIU Xin-Hai WANG Cheng-Zhi 《Communications in Theoretical Physics》 SCIE CAS CSCD 2009年第3期514-518,共5页
By properly selecting the time-dependent unitary transformation for the linear combination of the number operators, we construct a time-dependent invariant and derive the corresponding auxiliary equations for the dege... By properly selecting the time-dependent unitary transformation for the linear combination of the number operators, we construct a time-dependent invariant and derive the corresponding auxiliary equations for the degenerate and non-degenerate coupled parametric down-conversion system with driving term. By means of this invariant and the Lewis-Riesenfeld quantum invariant theory, we obtain closed formulae of the quantum state and the evolution operator of the system. We show that the time evolution of the quantum system directly leads to production of various generalized one- and two-mode combination squeezed states, and the squeezed effect is independent of the driving term of the Hamiltonian. In some special cases, the current solution can reduce to the results of the previous works. 展开更多
关键词 coupled parametric down-conversion time evolution Lewis-Riesenfeld invariant theory Schrodinger equation squeezed states
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An underwater acoustic data compression method based on compressed sensing 被引量:1
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作者 郭晓乐 杨坤德 +1 位作者 史阳 段睿 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第8期1981-1989,共9页
The use of underwater acoustic data has rapidly expanded with the application of multichannel, large-aperture underwater detection arrays. This study presents an underwater acoustic data compression method that is bas... The use of underwater acoustic data has rapidly expanded with the application of multichannel, large-aperture underwater detection arrays. This study presents an underwater acoustic data compression method that is based on compressed sensing. Underwater acoustic signals are transformed into the sparse domain for data storage at a receiving terminal, and the improved orthogonal matching pursuit(IOMP) algorithm is used to reconstruct the original underwater acoustic signals at a data processing terminal. When an increase in sidelobe level occasionally causes a direction of arrival estimation error, the proposed compression method can achieve a 10 times stronger compression for narrowband signals and a 5 times stronger compression for wideband signals than the orthogonal matching pursuit(OMP) algorithm. The IOMP algorithm also reduces the computing time by about 20% more than the original OMP algorithm. The simulation and experimental results are discussed. 展开更多
关键词 compressed sensing underwater acoustic signal compression ratio improved orthogonal matching pursuit(IOMP)
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Functional reconstruction of ischemic contracture in the lower limb 被引量:1
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作者 TANG Hao ZHANG Shao-cheng TAN Zhang-yong ZHU Hong-wei ZHANG Qiu-lin LI Ming 《Chinese Journal of Traumatology》 CAS 2011年第2期96-99,共4页
Objective: To discuss the method of functional reconstruction of ischemic contracture in the lower limb and propose a classification protocol for ischemic contracture in the lower limb based on its severity and progn... Objective: To discuss the method of functional reconstruction of ischemic contracture in the lower limb and propose a classification protocol for ischemic contracture in the lower limb based on its severity and prognosis. Methods: Atotal of 42 patients with ischemic contracture in the lower limb were included in this study. According to different types of disturbance and degrees of severity, surgical reconstructions consisting of nerve decompression, tendon lengthening or transfer, intrinsic foot muscle release and sural-tibial nerve anastomosis were performed in every patient. Results: Postoperatively, all patients were able to walk on flat ground. Drop foot was corrected in 10 patients, and 5 patients still felt some difficulty during stair activity. Split Achilles tendon transfer to flexor hallucis longus tendon was performed in 12 patients, and their walking stability was improved. Seven patients accepted ipsilateral suraltibial nerve anastomosis, and sensitivity recovery reached to S2 in 2 patients and S3 in 5 patients. Conclusions: Iscbemic contracture in the lower limb is a devastating complication after lower limb trauma. The prevention of contracture is much more important than the treatment of an established contracture. Split Achilles tendon transfer to flexor hallucis longus tendon and sural-tibial nerve anastomosis, which was initially implemented by us, could improve the functional recovery of ischemic contracture in lower limbs, and thus provides a new alternative for functional reconstruction of ischemic contracture in the lower limb. 展开更多
关键词 Ischemic contracture CLASSIFICATION Recovery of function
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Underwater sonar target imaging via compressed sensing with M sequences 被引量:1
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作者 Huichen YAN Jia XU +2 位作者 Xiang-Gen XIA Xudong ZHANG Teng LONG 《Science China Earth Sciences》 SCIE EI CAS CSCD 2016年第12期111-120,共10页
Due to the low sound propagation speed, the tradeoff between high azimuth resolution and wide imaging swath has severely limited the application of sonar underwater target imaging. However, based on compressed sensing... Due to the low sound propagation speed, the tradeoff between high azimuth resolution and wide imaging swath has severely limited the application of sonar underwater target imaging. However, based on compressed sensing(CS) technique, it is feasible to image targets with merely one pulse and thus avoid the above tradeoff. To investigate the possible waveforms for CS-based underwater imaging, the deterministic M sequences widely used in sonar applications are introduced in this paper. By analyzing the compressive matrix constructed from M sequences, the coherence parameter and the restricted isometry property(RIP) of the matrix are derived. Also, the feasibility and advances of M sequence are demonstrated by being compared with the existing Alltop sequence in underwater CS imaging framework. Finally, the results of numerical simulations and a real experiment are provided to reveal the effectiveness of the proposed signal. 展开更多
关键词 SONAR high-resolution imaging compressed sensing M sequence coherence parameter restricted isometry property
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