AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens. METHODS: We recruited 105 su...AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens. METHODS: We recruited 105 subjects to form three different target groups: treated group (n=44) undergoing treatment for IBS, untreated group (n =31) meeting the Rome Ⅱ criteria without treatment for IBS, control group (n = 30) with no IBS symptoms. RESULTS: SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P〈0.01). The number of positive SPTs was greater in the IBS group than in the control group (P〈 0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P= 0.03). CONCLUSION: Positive food SPT is higher in IBS patients than in controls.展开更多
基金Supported by a grant from the Korea Society of Neurogastroen-terology and Motility Research Funds (project No. 2003530)
文摘AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens. METHODS: We recruited 105 subjects to form three different target groups: treated group (n=44) undergoing treatment for IBS, untreated group (n =31) meeting the Rome Ⅱ criteria without treatment for IBS, control group (n = 30) with no IBS symptoms. RESULTS: SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P〈0.01). The number of positive SPTs was greater in the IBS group than in the control group (P〈 0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P= 0.03). CONCLUSION: Positive food SPT is higher in IBS patients than in controls.